HUT75223A - Process for the production of combinatorial compound libraries - Google Patents
Process for the production of combinatorial compound libraries Download PDFInfo
- Publication number
- HUT75223A HUT75223A HU9601588A HU9601588A HUT75223A HU T75223 A HUT75223 A HU T75223A HU 9601588 A HU9601588 A HU 9601588A HU 9601588 A HU9601588 A HU 9601588A HU T75223 A HUT75223 A HU T75223A
- Authority
- HU
- Hungary
- Prior art keywords
- ligand
- library
- ligands
- tag
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93810864 | 1993-12-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9601588D0 HU9601588D0 (en) | 1996-08-28 |
| HUT75223A true HUT75223A (en) | 1997-04-28 |
Family
ID=8215084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9601588A HUT75223A (en) | 1993-12-09 | 1994-11-28 | Process for the production of combinatorial compound libraries |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0733213A1 (ja) |
| JP (1) | JPH09508355A (ja) |
| AU (1) | AU1068295A (ja) |
| CA (1) | CA2175078A1 (ja) |
| FI (1) | FI962371L (ja) |
| HU (1) | HUT75223A (ja) |
| IL (1) | IL111906A0 (ja) |
| NO (1) | NO962186L (ja) |
| WO (1) | WO1995016209A1 (ja) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7034110B2 (en) | 1994-01-05 | 2006-04-25 | Arqule, Inc. | Method of identifying chemical compounds having selected properties for a particular application |
| US5712171A (en) | 1995-01-20 | 1998-01-27 | Arqule, Inc. | Method of generating a plurality of chemical compounds in a spatially arranged array |
| AU5110096A (en) * | 1995-03-28 | 1996-10-16 | Novartis Ag | Process for the production of combinatorial compound libraries |
| AU7247896A (en) * | 1995-09-29 | 1997-04-17 | Scripps Research Institute, The | Protein signature analysis |
| EP0868427B1 (en) * | 1995-12-18 | 2003-05-14 | Praecis Pharmaceuticals Incorporated | Methods for identifying compounds that bind to a target |
| US5866341A (en) * | 1996-04-03 | 1999-02-02 | Chugai Pharmaceutical Co., Ltd. | Compositions and methods for screening drug libraries |
| US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
| ATE481487T1 (de) | 1998-11-27 | 2010-10-15 | Ucb Sa | Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung |
| AU3494500A (en) * | 1999-02-17 | 2000-09-04 | Deltagen Proteomics, Inc. | Methods for substrate-ligand interaction screening |
| WO2000057183A1 (en) * | 1999-03-23 | 2000-09-28 | Biovation Limited | Protein isolation and analysis |
| US6911429B2 (en) | 1999-04-01 | 2005-06-28 | Transition Therapeutics Inc. | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| US6864235B1 (en) | 1999-04-01 | 2005-03-08 | Eva A. Turley | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| WO2000066259A1 (en) | 1999-05-05 | 2000-11-09 | Ut-Battelle, Llc | Method and apparatus for combinatorial chemistry |
| US7351540B1 (en) | 2000-03-17 | 2008-04-01 | Merck Patent Gmbh | Protein isolation and analysis |
| WO2001086296A2 (en) * | 2000-05-05 | 2001-11-15 | Agilix Corporation | Highly multiplexed reporter carrier systems |
| DE10117274B4 (de) * | 2001-04-06 | 2005-03-03 | Hte Ag The High Throughput Experimentation Company | Verfahren zur Analyse und Archivierung von wenigstens einer Materialbibliothek |
| EP1967525B1 (en) | 2001-05-08 | 2012-11-14 | Darwin Molecular Corporation | A method for regulating immune function in primates using the foxp3 protein |
| CA2466861A1 (en) * | 2001-11-06 | 2003-07-10 | Agilix Corporation | Sensitive coded detection systems |
| EP1572976B1 (en) | 2002-11-21 | 2010-09-15 | Celltech R & D, Inc. | Modulating immune responses |
| DE602005023286D1 (de) | 2004-03-31 | 2010-10-14 | Kazuo Shinya | Verfahren zum biosubstanzeinfang, zur strukturanalyse oder/und identifizierung unter verwendung einer markierungssubstanz |
| WO2022235929A1 (en) | 2021-05-05 | 2022-11-10 | Radius Pharmaceuticals, Inc. | Animal model having homologous recombination of mouse pth1 receptor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02104595A (ja) * | 1988-03-04 | 1990-04-17 | Univ Alabama | 非ペプチドのペプチド相当物及びそのデザイン方法 |
| US5650489A (en) * | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| DE69227895D1 (de) * | 1991-02-04 | 1999-01-28 | Akzo Nobel Nv | FAKTOR IIa INHIBITOREN |
| US5770358A (en) * | 1991-09-18 | 1998-06-23 | Affymax Technologies N.V. | Tagged synthetic oligomer libraries |
-
1994
- 1994-11-28 JP JP7515935A patent/JPH09508355A/ja active Pending
- 1994-11-28 AU AU10682/95A patent/AU1068295A/en not_active Abandoned
- 1994-11-28 EP EP95901447A patent/EP0733213A1/en not_active Withdrawn
- 1994-11-28 HU HU9601588A patent/HUT75223A/hu unknown
- 1994-11-28 WO PCT/EP1994/003936 patent/WO1995016209A1/en not_active Ceased
- 1994-11-28 CA CA002175078A patent/CA2175078A1/en not_active Abandoned
- 1994-11-28 FI FI962371A patent/FI962371L/fi not_active Application Discontinuation
- 1994-12-07 IL IL11190694A patent/IL111906A0/xx unknown
-
1996
- 1996-05-29 NO NO962186A patent/NO962186L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO962186D0 (no) | 1996-05-29 |
| IL111906A0 (en) | 1995-03-15 |
| EP0733213A1 (en) | 1996-09-25 |
| AU1068295A (en) | 1995-06-27 |
| WO1995016209A1 (en) | 1995-06-15 |
| FI962371A7 (fi) | 1996-06-07 |
| HU9601588D0 (en) | 1996-08-28 |
| FI962371A0 (fi) | 1996-06-07 |
| JPH09508355A (ja) | 1997-08-26 |
| NO962186L (no) | 1996-05-29 |
| CA2175078A1 (en) | 1995-06-15 |
| FI962371L (fi) | 1996-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DGB9 | Succession in title of applicant |
Owner name: NOVARTIS AG., CH |
|
| DFD9 | Temporary protection cancelled due to non-payment of fee |