ID17468A - Senyawa-senyawa xanthin yang mempunyai terminal rantai-rantai cabang alkunol teraminasi - Google Patents

Senyawa-senyawa xanthin yang mempunyai terminal rantai-rantai cabang alkunol teraminasi

Info

Publication number: ID17468A
Authority: ID; Indonesia
Prior art keywords: alkunol; amused; xanthin; branches; compounds
Prior art date: 1996-06-07

Application number

IDP971927A

Other languages

English (en)

Indonesian (id)

Inventor

Ulrich Dr Gebert

Elisabeth Dr Defossa

Uwe Dr Heinelt

Karl Dr Rudolphi

John J Dr Grome

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-07

Filing date

1997-06-05

Publication date

1998-01-08

1996-06-07 Priority claimed from DE19622734A external-priority patent/DE19622734A1/de

1996-09-11 Priority claimed from DE1996136882 external-priority patent/DE19636882A1/de

1997-06-05 Application filed by Hoechst Ag filed Critical Hoechst Ag

1998-01-08 Publication of ID17468A publication Critical patent/ID17468A/id

Links

LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurology (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IDP971927A 1996-06-07 1997-06-05 Senyawa-senyawa xanthin yang mempunyai terminal rantai-rantai cabang alkunol teraminasi ID17468A (id)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19622734A DE19622734A1 (de)	1996-06-07	1996-06-07	Xanthinverbindungen mit terminal aminierten Alkinol-Seitenketten
DE1996136882 DE19636882A1 (de)	1996-09-11	1996-09-11	Xanthinverbindungen mit terminal aminierten Alkinol-Seitenketten

Publications (1)

Publication Number	Publication Date
ID17468A true ID17468A (id)	1998-01-08

Family

ID=26026371

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDP971927A ID17468A (id)	1996-06-07	1997-06-05	Senyawa-senyawa xanthin yang mempunyai terminal rantai-rantai cabang alkunol teraminasi

Country Status (26)

Country	Link
US (1)	US5965555A (fr)
EP (1)	EP0811623B1 (fr)
JP (1)	JP4263778B2 (fr)
KR (1)	KR100531964B1 (fr)
CN (1)	CN1064361C (fr)
AR (1)	AR013821A1 (fr)
AT (1)	ATE200288T1 (fr)
AU (1)	AU712717B2 (fr)
BR (1)	BR9703500B1 (fr)
CA (1)	CA2207258C (fr)
CZ (1)	CZ292509B6 (fr)
DE (1)	DE59703271D1 (fr)
DK (1)	DK0811623T3 (fr)
ES (1)	ES2155640T3 (fr)
GR (1)	GR3035711T3 (fr)
HU (1)	HU224702B1 (fr)
ID (1)	ID17468A (fr)
IL (1)	IL120998A (fr)
MX (1)	MX9704201A (fr)
MY (1)	MY117764A (fr)
NO (1)	NO307787B1 (fr)
NZ (1)	NZ328018A (fr)
PL (1)	PL186238B1 (fr)
PT (1)	PT811623E (fr)
RU (1)	RU2204561C2 (fr)
TW (1)	TW384289B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2284708A (en) *	1993-12-07	1995-06-14	At & T Corp	Method for passivation of multi-quantum well infrared photodetectors (QWIPS) to reduce dark current and to improve dark current uniformity
SI1953162T1 (sl) *	2001-02-24	2012-09-28	Boehringer Ingelheim Pharma	Ksantinski derivati, njihova priprava in njihova uporaba kot zdravila
AU2002322562A1 (en) *	2001-07-19	2003-03-03	Medical College Of Georgia Research Institute	Novel analogs of choline for neuroprotection and cognitive enhancement in neurodegenerative disorders
US7407955B2 (en)	2002-08-21	2008-08-05	Boehringer Ingelheim Pharma Gmbh & Co., Kg	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
CA2496249C (fr) *	2002-08-21	2012-01-24	Boehringer Ingelheim Pharma Gmbh & Co. Kg	8-[3-amino-piperidin-1-yl]-xanthines, leur production et leur utilisation comme medicament
US7501426B2 (en)	2004-02-18	2009-03-10	Boehringer Ingelheim International Gmbh	8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de)	2004-11-05	2006-05-11	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de)	2005-07-30	2007-02-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (fr)	2006-05-04	2007-11-07	Boehringer Ingelheim Pharma GmbH & Co.KG	Compositions d'inhibiteurs de la DPP IV
PE20080251A1 (es) *	2006-05-04	2008-04-25	Boehringer Ingelheim Int	Usos de inhibidores de dpp iv
BRPI0711558A2 (pt) *	2006-05-04	2011-11-08	Boeringer Ingelheim Internat Gmbh	polimorfos
NZ600126A (en) *	2007-08-17	2013-12-20	Boehringer Ingelheim Int	Purine derivatives for use in the treatment of fap-related diseases
PE20140960A1 (es)	2008-04-03	2014-08-15	Boehringer Ingelheim Int	Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) *	2008-06-03	2010-02-23	Boehringer Ingelheim Int	Tratamiento de nafld
UY32030A (es)	2008-08-06	2010-03-26	Boehringer Ingelheim Int	"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
BRPI0916997A2 (pt)	2008-08-06	2020-12-15	Boehringer Ingelheim International Gmbh	Inibidor de dpp-4 e seu uso
KR101657960B1 (ko) *	2008-08-15	2016-09-20	베링거 인겔하임 인터내셔날 게엠베하	Ｆａｂ-관련 질환의 치료에 사용하기 위한 푸린 유도체
AU2009290911A1 (en)	2008-09-10	2010-03-18	Boehringer Ingelheim International Gmbh	Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en)	2018-11-20	2020-05-21	Boehringer Ingelheim International Gmbh	Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
EP2382216A1 (fr)	2008-12-23	2011-11-02	Boehringer Ingelheim International GmbH	Formes de sel d'un composé organique
AR074990A1 (es)	2009-01-07	2011-03-02	Boehringer Ingelheim Int	Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
EA034869B1 (ru)	2009-11-27	2020-03-31	Бёрингер Ингельхайм Интернациональ Гмбх	Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин
MX341025B (es)	2010-05-05	2016-08-04	Boehringer Ingelheim Int Gmbh *	Terapia de combinacion.
PH12012502524A1 (en)	2010-06-24	2014-02-10	Boehringer Ingelheim Int	Diabetes therapy
US9034883B2 (en)	2010-11-15	2015-05-19	Boehringer Ingelheim International Gmbh	Vasoprotective and cardioprotective antidiabetic therapy
EP3517539B1 (fr)	2011-07-15	2022-12-14	Boehringer Ingelheim International GmbH	Dérivé de quinazoline dimère substitué, sa préparation et son utilisation dans des compositions pharmaceutiques pour le traitement du diabète de type i et ii
US9555001B2 (en)	2012-03-07	2017-01-31	Boehringer Ingelheim International Gmbh	Pharmaceutical composition and uses thereof
US20130303554A1 (en)	2012-05-14	2013-11-14	Boehringer Ingelheim International Gmbh	Use of a dpp-4 inhibitor in sirs and/or sepsis
JP6224084B2 (ja)	2012-05-14	2017-11-01	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (fr)	2012-05-24	2013-11-28	Boehringer Ingelheim International Gmbh	Dérivé de xanthine en tant qu'inhibiteur de la dpp-4 à utiliser dans la modification de l'apport alimentaire et dans la régulation des préférences alimentaires
US9526728B2 (en)	2014-02-28	2016-12-27	Boehringer Ingelheim International Gmbh	Medical use of a DPP-4 inhibitor
CN109310697A (zh)	2016-06-10	2019-02-05	勃林格殷格翰国际有限公司	利格列汀和二甲双胍的组合

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4007197A (en) *	1975-06-10	1977-02-08	The Dow Chemical Company	Process for preparing phosphorothioates and phenylphosphonothioates
DE3525801A1 (de) *	1985-07-19	1987-01-22	Hoechst Ag	Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
EP0223403B1 (fr) *	1985-10-25	1993-08-04	Beecham Group Plc	Dérivé de pipéridine, sa préparation et son utilisation comme médicament
GB8621870D0 (en) *	1986-09-11	1986-10-15	Beecham Group Plc	Active compounds
GB8826595D0 (en) *	1988-11-14	1988-12-21	Beecham Wuelfing Gmbh & Co Kg	Active compounds
US5473070A (en) *	1992-11-16	1995-12-05	Cell Therapeutics, Inc.	Substituted long chain alcohol xanthine compounds
IT1274241B (it) *	1993-12-03	1997-07-15	Smithkline Beecham Farma	Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono
RU2075572C1 (ru) *	1994-11-22	1997-03-20	Алексей Егорович Пережилов	Способ формирования изоляционной завесы вокруг горных выработок

1997
- 1997-05-30 US US08/866,347 patent/US5965555A/en not_active Expired - Lifetime
- 1997-06-03 EP EP97108871A patent/EP0811623B1/fr not_active Expired - Lifetime
- 1997-06-03 DK DK97108871T patent/DK0811623T3/da active
- 1997-06-03 ES ES97108871T patent/ES2155640T3/es not_active Expired - Lifetime
- 1997-06-03 PT PT97108871T patent/PT811623E/pt unknown
- 1997-06-03 DE DE59703271T patent/DE59703271D1/de not_active Expired - Lifetime
- 1997-06-03 AT AT97108871T patent/ATE200288T1/de active
- 1997-06-04 CN CN97112930A patent/CN1064361C/zh not_active Expired - Fee Related
- 1997-06-05 NZ NZ328018A patent/NZ328018A/en not_active IP Right Cessation
- 1997-06-05 ID IDP971927A patent/ID17468A/id unknown
- 1997-06-05 AR ARP970102447A patent/AR013821A1/es active IP Right Grant
- 1997-06-05 IL IL12099897A patent/IL120998A/xx not_active IP Right Cessation
- 1997-06-05 CZ CZ19971742A patent/CZ292509B6/cs not_active IP Right Cessation
- 1997-06-05 AU AU24699/97A patent/AU712717B2/en not_active Ceased
- 1997-06-06 HU HU9701018A patent/HU224702B1/hu not_active IP Right Cessation
- 1997-06-06 NO NO972581A patent/NO307787B1/no not_active IP Right Cessation
- 1997-06-06 RU RU97109533/04A patent/RU2204561C2/ru not_active IP Right Cessation
- 1997-06-06 MY MYPI97002536A patent/MY117764A/en unknown
- 1997-06-06 JP JP16346697A patent/JP4263778B2/ja not_active Expired - Fee Related
- 1997-06-06 CA CA002207258A patent/CA2207258C/fr not_active Expired - Fee Related
- 1997-06-06 MX MX9704201A patent/MX9704201A/es not_active IP Right Cessation
- 1997-06-06 PL PL97320414A patent/PL186238B1/pl not_active IP Right Cessation
- 1997-06-07 KR KR1019970023483A patent/KR100531964B1/ko not_active Expired - Fee Related
- 1997-06-09 BR BRPI9703500-9A patent/BR9703500B1/pt not_active IP Right Cessation
- 1997-06-24 TW TW086108159A patent/TW384289B/zh active
2001
- 2001-04-06 GR GR20010400561T patent/GR3035711T3/el unknown

Also Published As

Publication number	Publication date
DK0811623T3 (da)	2001-07-23
BR9703500A (pt)	1998-10-06
JPH1059968A (ja)	1998-03-03
MX9704201A (es)	1998-04-30
TW384289B (en)	2000-03-11
CN1169994A (zh)	1998-01-14
CA2207258A1 (fr)	1997-12-07
NO307787B1 (no)	2000-05-29
RU2204561C2 (ru)	2003-05-20
MY117764A (en)	2004-08-30
HU224702B1 (en)	2006-01-30
IL120998A (en)	2000-07-16
ATE200288T1 (de)	2001-04-15
HUP9701018A2 (hu)	1998-12-28
DE59703271D1 (de)	2001-05-10
BR9703500B1 (pt)	2010-05-18
CA2207258C (fr)	2006-08-08
NO972581D0 (no)	1997-06-06
NZ328018A (en)	1998-09-24
KR19980024046A (ko)	1998-07-06
EP0811623B1 (fr)	2001-04-04
PL320414A1 (en)	1997-12-08
CZ174297A3 (en)	1997-12-17
NO972581L (no)	1997-12-08
US5965555A (en)	1999-10-12
GR3035711T3 (en)	2001-07-31
JP4263778B2 (ja)	2009-05-13
AR013821A1 (es)	2001-01-31
PL186238B1 (pl)	2003-12-31
HUP9701018A3 (en)	2000-01-28
EP0811623A1 (fr)	1997-12-10
KR100531964B1 (ko)	2006-03-17
CN1064361C (zh)	2001-04-11
PT811623E (pt)	2001-09-28
AU2469997A (en)	1997-12-11
IL120998A0 (en)	1997-11-20
CZ292509B6 (cs)	2003-10-15
HU9701018D0 (en)	1997-07-28
ES2155640T3 (es)	2001-05-16
AU712717B2 (en)	1999-11-11

Publication	Publication Date	Title
DE69519608D1 (de)	2001-01-18	Wasserdichter Verbinder
DE69515777D1 (de)	2000-04-27	Wasserdichter Verbinder
DE69828371D1 (de)	2005-02-03	Wasserdichter Verbinder
DE69831142D1 (de)	2005-09-15	Weiblicher steckverbinder
DE69423420D1 (de)	2000-04-20	Wasserdichter Verbinder
DE69617355D1 (de)	2002-01-10	Modularer Steckverbinder
DE69700207D1 (de)	1999-06-10	Modularer elekrischer Verbinder
DE69715800D1 (de)	2002-10-31	Verbinderteile
DE69939206D1 (de)	2008-09-11	Wasserdichter verbinder
GB2321347B (en)	1999-02-17	Waterproof connector and method of manufacturing the same
DE69902863D1 (de)	2002-10-17	Wasserdichter Verbinder
DE69924186D1 (de)	2005-04-21	Wasserdichter Verbinder
DE69933076D1 (de)	2006-10-19	Wasserdichter Verbinder und dessen Zusammenbau
DE59602143D1 (de)	1999-07-15	Riemenverbinder
DE69922589D1 (de)	2005-01-20	Wasserdichter Verbinder
DE69838190D1 (de)	2007-09-20	Wasserdichter Verbinder
DE59401596D1 (de)	1997-02-27	Riemenverbinder
DE69836511D1 (de)	2007-01-04	Verbesserter umgossener Verbinder und dessen Herstellungsverfahren
DE69802585D1 (de)	2002-01-03	Modularer Steckverbinder
EP0692846A3 (fr)	1997-05-28	Connecteur verrouillable
DE69514499D1 (de)	2000-02-17	Stromverbinder
FR2727256B3 (fr)	1996-09-27	Connecteur etanche ameliore
IT1286439B1 (it)	1998-07-08	Connettore elettrico impermeabilizzato
DE19780125D2 (de)	1999-07-15	Steckverbindung
ATA185596A (de)	1998-06-15	Schmuckstück