ID18075A - Penghambat thrombin - Google Patents

Penghambat thrombin

Info

Publication number
ID18075A
ID18075A IDP972947A ID972947A ID18075A ID 18075 A ID18075 A ID 18075A ID P972947 A IDP972947 A ID P972947A ID 972947 A ID972947 A ID 972947A ID 18075 A ID18075 A ID 18075A
Authority
ID
Indonesia
Prior art keywords
delayer
thrombin
thrombin delayer
Prior art date
Application number
IDP972947A
Other languages
English (en)
Indonesian (id)
Inventor
Van Boeckel
Adang Anton Egbert Peter
Peters Jacobus Albertus Maria
Rewinkel Johannes Bernar Maria
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of ID18075A publication Critical patent/ID18075A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDP972947A 1996-08-23 1997-08-22 Penghambat thrombin ID18075A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96202336 1996-08-23

Publications (1)

Publication Number Publication Date
ID18075A true ID18075A (id) 1998-02-26

Family

ID=8224306

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP972947A ID18075A (id) 1996-08-23 1997-08-22 Penghambat thrombin

Country Status (10)

Country Link
EP (1) EP0956293B1 (de)
AR (1) AR009302A1 (de)
AT (1) ATE282629T1 (de)
AU (1) AU4618197A (de)
DE (1) DE69731664D1 (de)
ID (1) ID18075A (de)
IL (1) IL121474A0 (de)
TW (1) TW515803B (de)
WO (1) WO1998007308A2 (de)
ZA (1) ZA977209B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0884325A1 (de) * 1997-04-24 1998-12-16 Akzo Nobel N.V. Inhibitoren des Thrombins, die einen peptid-Heterocyclus aufweisen
US5877156A (en) * 1997-04-24 1999-03-02 Akzo Nobel, N.V. Thrombin inhibitors
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
US7951823B2 (en) 2006-05-23 2011-05-31 Irm Llc Compounds and compositions as channel activating protease inhibitors
RU2419625C2 (ru) 2006-05-23 2011-05-27 Айрм Ллк Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы
KR20090108131A (ko) 2007-02-09 2009-10-14 아이알엠 엘엘씨 채널 활성화 프로테아제 억제제로서의 화합물 및 조성물
CN117143179B (zh) * 2023-09-18 2024-07-12 安徽峆一药业股份有限公司 一种凝血酶发色底物s-2238的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672582A (en) * 1993-04-30 1997-09-30 Merck & Co., Inc. Thrombin inhibitors
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
ZA951617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
JPH10513151A (ja) * 1994-12-22 1998-12-15 バイオケム ファーマ インコーポレイテッド トロンビン阻害剤としての複素環式ケトアルギニンペプチド
US5827860A (en) * 1995-06-07 1998-10-27 Ortho Pharmaceutical Corporation Peptidyl heterocycles useful in the treatment of thrombin related disorders
IL119466A (en) * 1995-11-03 2001-08-26 Akzo Nobel Nv Thrombin inhibitors, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1998007308A3 (en) 2000-08-24
ATE282629T1 (de) 2004-12-15
DE69731664D1 (de) 2004-12-23
AR009302A1 (es) 2000-04-12
AU4618197A (en) 1998-03-06
WO1998007308A2 (en) 1998-02-26
TW515803B (en) 2003-01-01
IL121474A0 (en) 1998-02-08
EP0956293A1 (de) 1999-11-17
EP0956293B1 (de) 2004-11-17
ZA977209B (en) 1998-02-20

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