ID18178A - GARAM10-AMINOALIFATIL-DIBENZ (b,f) OKSEPIN YANG EFEKTIF SEBAGAI ANTI-NEURODEGENERASI - Google Patents

GARAM10-AMINOALIFATIL-DIBENZ (b,f) OKSEPIN YANG EFEKTIF SEBAGAI ANTI-NEURODEGENERASI

Info

Publication number
ID18178A
ID18178A IDP971845A ID971845A ID18178A ID 18178 A ID18178 A ID 18178A ID P971845 A IDP971845 A ID P971845A ID 971845 A ID971845 A ID 971845A ID 18178 A ID18178 A ID 18178A
Authority
ID
Indonesia
Prior art keywords
salt10
octepins
aminoalifatil
dibenz
neurodegeneration
Prior art date
Application number
IDP971845A
Other languages
English (en)
Inventor
Kaspar Dr Zimmermann
Silvio Dr Roggo
Claudia Dr Betschart
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ID18178A publication Critical patent/ID18178A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDP971845A 1996-05-30 1997-05-30 GARAM10-AMINOALIFATIL-DIBENZ (b,f) OKSEPIN YANG EFEKTIF SEBAGAI ANTI-NEURODEGENERASI ID18178A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH135296 1996-05-30

Publications (1)

Publication Number Publication Date
ID18178A true ID18178A (id) 1998-03-12

Family

ID=4208469

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP971845A ID18178A (id) 1996-05-30 1997-05-30 GARAM10-AMINOALIFATIL-DIBENZ (b,f) OKSEPIN YANG EFEKTIF SEBAGAI ANTI-NEURODEGENERASI

Country Status (10)

Country Link
AR (1) AR008371A1 (id)
AU (1) AU3030397A (id)
CO (1) CO5080765A1 (id)
CZ (1) CZ296134B6 (id)
ID (1) ID18178A (id)
PE (1) PE70398A1 (id)
PL (1) PL191728B1 (id)
TR (1) TR199802482T2 (id)
WO (1) WO1997045422A1 (id)
ZA (1) ZA974802B (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000075127A1 (en) * 1999-06-03 2000-12-14 Nippon Suisan Kaisha, Ltd. Tricyclic fused heterocycle compounds, process for preparing the same and use thereof
US7355042B2 (en) 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
AU2003235799A1 (en) * 2002-01-08 2003-07-24 Nordic Bioscience A/S Modulation of iamt (pimt or pcmt) in immune system
TW200505435A (en) * 2003-01-29 2005-02-16 Novartis Ag Treatment of ocular disorders
AR046320A1 (es) * 2003-11-06 2005-11-30 Novartis Ag Composiciones farmaceuticas estabilizadas de dibenzo-oxepina.
KR101264444B1 (ko) 2004-09-21 2013-05-20 히프니언 인크. 록사핀 유사체 및 이것의 사용 방법
WO2006049734A2 (en) 2004-10-29 2006-05-11 Hypnion, Inc. Quetiapine analogs and methods of use thereof
EP1757284A1 (en) * 2005-08-25 2007-02-28 Santhera Pharmaceuticals (Schweiz) AG Use of N-(dibenz(b,f)oxepin-10ylmethyl)-N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of muscular dystrophy
EP1842539A1 (en) * 2006-04-05 2007-10-10 Santhera Pharmaceuticals (Schweiz) AG Use of N- (dibenz(b,f)oxepin-10-ylmethyl)N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of congenital muscular dystrophy or myopathy resulting from collagen VI deficiency
US9937144B2 (en) 2013-01-30 2018-04-10 The Johns Hopkins University Treatment of drug abuse by preventing GAPDH nitrosylation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3100207A (en) * 1959-07-08 1963-08-06 Smith Kline French Lab 10-aminoalkylbenzo[b,f]thiepin and -dibenz[b,f]oxepin derivatives
DE1493782B1 (de) * 1964-06-29 1969-12-11 Geigy Ag J R Basisch substituierte Dibenzo[b,f]-oxepine und deren nicht-toxische Salze
CH585745A5 (id) * 1973-06-08 1977-03-15 Hoffmann La Roche
DE59607332D1 (de) * 1995-02-08 2001-08-30 Novartis Ag Antineurodegenerativ wirksame 10-Aminoaliphatyl-dibenz- b,f oxepine

Also Published As

Publication number Publication date
TR199802482T2 (xx) 1999-02-22
ZA974802B (en) 1998-11-30
CZ387898A3 (cs) 1999-02-17
AU3030397A (en) 1998-01-05
AR008371A1 (es) 2000-01-19
PE70398A1 (es) 1998-11-09
PL191728B1 (pl) 2006-06-30
CO5080765A1 (es) 2001-09-25
CZ296134B6 (cs) 2006-01-11
WO1997045422A1 (en) 1997-12-04
PL330238A1 (en) 1999-05-10

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