TR199802482T2 - Anti-n�rodejenaratif olarak etkili-10-aminoalifatil-dibenz $b,f] oksepin tuzlar�. - Google Patents
Anti-n�rodejenaratif olarak etkili-10-aminoalifatil-dibenz $b,f] oksepin tuzlar�.Info
- Publication number
- TR199802482T2 TR199802482T2 TR1998/02482T TR9802482T TR199802482T2 TR 199802482 T2 TR199802482 T2 TR 199802482T2 TR 1998/02482 T TR1998/02482 T TR 1998/02482T TR 9802482 T TR9802482 T TR 9802482T TR 199802482 T2 TR199802482 T2 TR 199802482T2
- Authority
- TR
- Turkey
- Prior art keywords
- aliphatic
- aminoaliphatyl
- dibenz
- salts
- oxepin
- Prior art date
Links
- 230000002555 anti-neurodegenerative effect Effects 0.000 title abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- ATYBXHSAIOKLMG-UHFFFAOYSA-N oxepin Chemical compound O1C=CC=CC=C1 ATYBXHSAIOKLMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH135296 | 1996-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199802482T2 true TR199802482T2 (xx) | 1999-02-22 |
Family
ID=4208469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/02482T TR199802482T2 (xx) | 1996-05-30 | 1997-05-28 | Anti-n�rodejenaratif olarak etkili-10-aminoalifatil-dibenz $b,f] oksepin tuzlar�. |
Country Status (10)
| Country | Link |
|---|---|
| AR (1) | AR008371A1 (id) |
| AU (1) | AU3030397A (id) |
| CO (1) | CO5080765A1 (id) |
| CZ (1) | CZ296134B6 (id) |
| ID (1) | ID18178A (id) |
| PE (1) | PE70398A1 (id) |
| PL (1) | PL191728B1 (id) |
| TR (1) | TR199802482T2 (id) |
| WO (1) | WO1997045422A1 (id) |
| ZA (1) | ZA974802B (id) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000075127A1 (en) * | 1999-06-03 | 2000-12-14 | Nippon Suisan Kaisha, Ltd. | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof |
| US7355042B2 (en) | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| AU2003235799A1 (en) * | 2002-01-08 | 2003-07-24 | Nordic Bioscience A/S | Modulation of iamt (pimt or pcmt) in immune system |
| TW200505435A (en) * | 2003-01-29 | 2005-02-16 | Novartis Ag | Treatment of ocular disorders |
| AR046320A1 (es) * | 2003-11-06 | 2005-11-30 | Novartis Ag | Composiciones farmaceuticas estabilizadas de dibenzo-oxepina. |
| KR101264444B1 (ko) | 2004-09-21 | 2013-05-20 | 히프니언 인크. | 록사핀 유사체 및 이것의 사용 방법 |
| WO2006049734A2 (en) | 2004-10-29 | 2006-05-11 | Hypnion, Inc. | Quetiapine analogs and methods of use thereof |
| EP1757284A1 (en) * | 2005-08-25 | 2007-02-28 | Santhera Pharmaceuticals (Schweiz) AG | Use of N-(dibenz(b,f)oxepin-10ylmethyl)-N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of muscular dystrophy |
| EP1842539A1 (en) * | 2006-04-05 | 2007-10-10 | Santhera Pharmaceuticals (Schweiz) AG | Use of N- (dibenz(b,f)oxepin-10-ylmethyl)N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of congenital muscular dystrophy or myopathy resulting from collagen VI deficiency |
| US9937144B2 (en) | 2013-01-30 | 2018-04-10 | The Johns Hopkins University | Treatment of drug abuse by preventing GAPDH nitrosylation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3100207A (en) * | 1959-07-08 | 1963-08-06 | Smith Kline French Lab | 10-aminoalkylbenzo[b,f]thiepin and -dibenz[b,f]oxepin derivatives |
| DE1493782B1 (de) * | 1964-06-29 | 1969-12-11 | Geigy Ag J R | Basisch substituierte Dibenzo[b,f]-oxepine und deren nicht-toxische Salze |
| CH585745A5 (id) * | 1973-06-08 | 1977-03-15 | Hoffmann La Roche | |
| DE59607332D1 (de) * | 1995-02-08 | 2001-08-30 | Novartis Ag | Antineurodegenerativ wirksame 10-Aminoaliphatyl-dibenz- b,f oxepine |
-
1997
- 1997-05-27 AR ARP970102247A patent/AR008371A1/es unknown
- 1997-05-28 PL PL330238A patent/PL191728B1/pl unknown
- 1997-05-28 CZ CZ0387898A patent/CZ296134B6/cs not_active IP Right Cessation
- 1997-05-28 WO PCT/EP1997/002794 patent/WO1997045422A1/en not_active Ceased
- 1997-05-28 AU AU30303/97A patent/AU3030397A/en not_active Abandoned
- 1997-05-28 TR TR1998/02482T patent/TR199802482T2/xx unknown
- 1997-05-28 PE PE1997000433A patent/PE70398A1/es not_active IP Right Cessation
- 1997-05-29 CO CO97029926A patent/CO5080765A1/es unknown
- 1997-05-30 ID IDP971845A patent/ID18178A/id unknown
- 1997-05-30 ZA ZA974802A patent/ZA974802B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA974802B (en) | 1998-11-30 |
| CZ387898A3 (cs) | 1999-02-17 |
| AU3030397A (en) | 1998-01-05 |
| AR008371A1 (es) | 2000-01-19 |
| ID18178A (id) | 1998-03-12 |
| PE70398A1 (es) | 1998-11-09 |
| PL191728B1 (pl) | 2006-06-30 |
| CO5080765A1 (es) | 2001-09-25 |
| CZ296134B6 (cs) | 2006-01-11 |
| WO1997045422A1 (en) | 1997-12-04 |
| PL330238A1 (en) | 1999-05-10 |
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