ID18416A - Inhibitor metaloprotease diheterosiklik - Google Patents
Inhibitor metaloprotease diheterosiklikInfo
- Publication number
- ID18416A ID18416A IDP972993A ID972993A ID18416A ID 18416 A ID18416 A ID 18416A ID P972993 A IDP972993 A ID P972993A ID 972993 A ID972993 A ID 972993A ID 18416 A ID18416 A ID 18416A
- Authority
- ID
- Indonesia
- Prior art keywords
- diheterosiclic
- metaloprotease
- inhibitors
- metaloprotease inhibitors
- diheterosiclic metaloprotease
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/06—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2484696P | 1996-08-28 | 1996-08-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID18416A true ID18416A (id) | 1998-04-09 |
Family
ID=21822698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDP972993A ID18416A (id) | 1996-08-28 | 1997-08-28 | Inhibitor metaloprotease diheterosiklik |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US6121258A (de) |
| EP (1) | EP0923561B1 (de) |
| JP (1) | JP3347331B2 (de) |
| KR (1) | KR20000035920A (de) |
| CN (1) | CN1228772A (de) |
| AR (1) | AR009457A1 (de) |
| AT (1) | ATE226573T1 (de) |
| AU (1) | AU734834B2 (de) |
| BR (1) | BR9712085A (de) |
| CA (1) | CA2263917A1 (de) |
| CO (1) | CO4920240A1 (de) |
| CZ (1) | CZ62699A3 (de) |
| DE (1) | DE69716615T2 (de) |
| DK (1) | DK0923561T3 (de) |
| HU (1) | HUP0000210A3 (de) |
| ID (1) | ID18416A (de) |
| IL (1) | IL128664A (de) |
| NO (1) | NO314934B1 (de) |
| NZ (1) | NZ334254A (de) |
| PE (1) | PE2599A1 (de) |
| PL (1) | PL331795A1 (de) |
| SK (1) | SK25799A3 (de) |
| TR (1) | TR199900382T2 (de) |
| WO (1) | WO1998008823A1 (de) |
| ZA (1) | ZA977696B (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0927168T3 (da) * | 1996-08-28 | 2003-03-10 | Procter & Gamble | 1,3-diheterocykliske metalloproteaseinhibitorer |
| KR100352316B1 (ko) | 1997-07-31 | 2002-09-12 | 더 프록터 앤드 갬블 캄파니 | 메탈로프로테아제억제제로서사용되는술포닐아미노치환히드록삼산유도체 |
| US6410580B1 (en) | 1998-02-04 | 2002-06-25 | Novartis Ag | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| JP4750272B2 (ja) | 1998-02-04 | 2011-08-17 | ノバルティス アーゲー | マトリックス分解メタロプロテイナーゼを阻害するスルホニルアミノ誘導体 |
| US6846478B1 (en) | 1998-02-27 | 2005-01-25 | The Procter & Gamble Company | Promoting whole body health |
| AU1708099A (en) | 1998-06-03 | 1999-12-20 | Amgen, Inc. | N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
| US6333340B1 (en) * | 1998-08-14 | 2001-12-25 | Gpi Nil Holdings, Inc. | Small molecule sulfonamides for vision and memory disorders |
| US6339101B1 (en) * | 1998-08-14 | 2002-01-15 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders |
| US6509337B1 (en) * | 1998-09-17 | 2003-01-21 | Pfizer Inc. | Arylsulfonyl Hydroxamic Acid derivatives as MMP and TNF inhibitors |
| US6300341B1 (en) | 1998-09-30 | 2001-10-09 | The Procter & Gamble Co. | 2-substituted heterocyclic sulfonamides |
| BR9914197A (pt) * | 1998-09-30 | 2001-07-03 | Procter & Gamble | Processo de tratamento da perda de cabelos com o uso de cetoamidas |
| US6307049B1 (en) | 1998-09-30 | 2001-10-23 | The Procter & Gamble Co. | Heterocyclic 2-substituted ketoamides |
| TR200101549T2 (tr) * | 1998-12-02 | 2001-11-21 | Pfizer Products Inc. | p53-Familyasından bir proteinin yapısal kararlılığının canlandırılmasına yönelik metotlar. |
| US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
| US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
| AR022423A1 (es) * | 1999-01-27 | 2002-09-04 | American Cyanamid Co | Compuestos derivados de acidos 2,3,4,5-tetrahidro-1h-[1,4]benzodiazepina-3-hidroxamicos, composicion farmaceutica que los comprenden, y el uso de losmismos para la manufactura de un medicamento |
| US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
| US6544984B1 (en) | 1999-01-27 | 2003-04-08 | American Cyanamid Company | 2,3,4,5-tetrahydro-1H-(1,4)benzodiazepine-3-hydroxamic acids |
| US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| CN1178915C (zh) | 1999-01-27 | 2004-12-08 | 惠氏控股有限公司 | 含有炔基的异羟肟酸衍生物、其制备及其作为基质金属蛋白酶抑制剂/TNF-α转变酶抑制剂的用途 |
| HK1044935A1 (zh) | 1999-03-03 | 2002-11-08 | The Procter & Gamble Company | 双异取代的金属蛋白酶抑制剂 |
| PL350340A1 (en) | 1999-03-03 | 2002-12-02 | Procter & Gamble | Alkenyl- and alkynyl-containing metalloprotease inhibitors |
| JP2003523337A (ja) * | 2000-02-21 | 2003-08-05 | 藤沢薬品工業株式会社 | マトリックスメタロプロタアーゼ阻害剤としてのチアゼピニルヒドロキサム酸誘導体 |
| JP4754155B2 (ja) | 2000-06-30 | 2011-08-24 | ザ プロクター アンド ギャンブル カンパニー | 全身の健康の増進 |
| US8283135B2 (en) | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| MXPA03011095A (es) * | 2001-05-29 | 2005-04-28 | Guilford Pharm Inc | Metodo para tratar una lesion nerviosa causada por cirugia. |
| MXPA04004010A (es) | 2001-11-01 | 2004-07-23 | Wyeth Corp | Acidos hidroxamicos de aril sulfonamida alenicos como inhibidores de tace y metaloproteinasa de matriz. |
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
| US7199155B2 (en) | 2002-12-23 | 2007-04-03 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors |
| CA2526222A1 (en) * | 2003-05-16 | 2004-12-02 | Arriva Pharmaceuticals, Inc. | Treatment of respiratory disease associated with matrix metalloprotease inhibitors |
| CA2536041A1 (en) * | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| JP4777738B2 (ja) * | 2004-10-14 | 2011-09-21 | 株式会社 資生堂 | Ａｄａｍ活性阻害物質によるしわの防止または改善 |
| JP2007119444A (ja) * | 2005-09-29 | 2007-05-17 | Shiseido Co Ltd | Ａｄａｍ阻害剤によるしわの防止または改善 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8601368D0 (en) * | 1986-01-21 | 1986-02-26 | Ici America Inc | Hydroxamic acids |
| DK77487A (da) * | 1986-03-11 | 1987-09-12 | Hoffmann La Roche | Hydroxylaminderivater |
| FR2609289B1 (fr) * | 1987-01-06 | 1991-03-29 | Bellon Labor Sa Roger | Nouveaux composes a activite d'inhibiteurs de collagenase, procede pour les preparer et compositions pharmaceutiques contenant ces composes |
| GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| GB8919251D0 (en) * | 1989-08-24 | 1989-10-04 | British Bio Technology | Compounds |
| DE4011172A1 (de) * | 1990-04-06 | 1991-10-10 | Degussa | Verbindungen zur bekaempfung von pflanzenkrankheiten |
| US5183900A (en) * | 1990-11-21 | 1993-02-02 | Galardy Richard E | Matrix metalloprotease inhibitors |
| US5189178A (en) * | 1990-11-21 | 1993-02-23 | Galardy Richard E | Matrix metalloprotease inhibitors |
| GB9102635D0 (en) * | 1991-02-07 | 1991-03-27 | British Bio Technology | Compounds |
| GB9107368D0 (en) * | 1991-04-08 | 1991-05-22 | Smithkline Beecham Plc | Novel compounds |
| IL98681A (en) * | 1991-06-30 | 1997-06-10 | Yeda Rehovot And Dev Company L | Pharmaceutical compositions comprising hydroxamate derivatives for iron removal from mammalian cells and from pathogenic organisms and some novel hydroxamate derivatives |
| DE4127842A1 (de) * | 1991-08-22 | 1993-02-25 | Rhone Poulenc Rorer Gmbh | 5-((omega)-arylalky)-2-thienyl alkansaeuren, ihre salze und/oder ihre derivate |
| JPH05125029A (ja) * | 1991-11-06 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド化合物又はその塩 |
| EP0634998B1 (de) * | 1992-04-07 | 1997-03-19 | British Biotech Pharmaceuticals Limited | Hydroxamsäure enthaltende collagenase-inhibitoren und cytokinaktivitätsinhibitoren |
| WO1993021942A2 (en) * | 1992-05-01 | 1993-11-11 | British Biotech Pharmaceuticals Limited | Use of mmp inhibitors |
| AU666727B2 (en) * | 1992-06-25 | 1996-02-22 | F. Hoffmann-La Roche Ag | Hydroxamic acid derivatives |
| GB9215665D0 (en) * | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
| GB9223904D0 (en) * | 1992-11-13 | 1993-01-06 | British Bio Technology | Inhibition of cytokine production |
| US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| GB9411598D0 (en) * | 1994-06-09 | 1994-08-03 | Hoffmann La Roche | Hydroxamic acid derivatives |
| JPH10501806A (ja) * | 1994-06-22 | 1998-02-17 | ブリティッシュ バイオテック ファーマシューティカルズ リミテッド | 金属タンパク質分解酵素阻害剤 |
| DK0821671T3 (da) * | 1995-04-20 | 2001-04-23 | Pfizer | Arylsulfonylhydroxamsyrederivater som MMP- og TNF-inhibitorer |
| KR100475206B1 (ko) * | 1995-11-13 | 2005-12-16 | 훽스트 악티엔게젤샤프트 | 사이클릭및헤테로사이클릭N-치환된α-이미노하이드록삼산및카복실산 |
| ES2233275T3 (es) * | 1995-12-08 | 2005-06-16 | Agouron Pharmaceuticals, Inc. | Intermediarios que sirven para la preparacion de inhibidores de metaloproteinasas. |
| ES2183905T3 (es) * | 1995-12-20 | 2003-04-01 | Hoffmann La Roche | Inhibidores de metaloproteasa de matriz. |
-
1997
- 1997-08-22 AT AT97939443T patent/ATE226573T1/de not_active IP Right Cessation
- 1997-08-22 WO PCT/US1997/014553 patent/WO1998008823A1/en not_active Ceased
- 1997-08-22 EP EP97939443A patent/EP0923561B1/de not_active Expired - Lifetime
- 1997-08-22 DE DE69716615T patent/DE69716615T2/de not_active Expired - Fee Related
- 1997-08-22 AU AU41530/97A patent/AU734834B2/en not_active Ceased
- 1997-08-22 KR KR1019997001656A patent/KR20000035920A/ko not_active Ceased
- 1997-08-22 DK DK97939443T patent/DK0923561T3/da active
- 1997-08-22 BR BR9712085-5A patent/BR9712085A/pt unknown
- 1997-08-22 SK SK257-99A patent/SK25799A3/sk unknown
- 1997-08-22 NZ NZ334254A patent/NZ334254A/xx unknown
- 1997-08-22 HU HU0000210A patent/HUP0000210A3/hu unknown
- 1997-08-22 CA CA002263917A patent/CA2263917A1/en not_active Abandoned
- 1997-08-22 CN CN97197544A patent/CN1228772A/zh active Pending
- 1997-08-22 CZ CZ99626A patent/CZ62699A3/cs unknown
- 1997-08-22 JP JP51171398A patent/JP3347331B2/ja not_active Expired - Fee Related
- 1997-08-22 PL PL97331795A patent/PL331795A1/xx unknown
- 1997-08-22 IL IL12866497A patent/IL128664A/xx not_active IP Right Cessation
- 1997-08-22 TR TR1999/00382T patent/TR199900382T2/xx unknown
- 1997-08-26 US US08/918,957 patent/US6121258A/en not_active Expired - Fee Related
- 1997-08-27 ZA ZA9707696A patent/ZA977696B/xx unknown
- 1997-08-27 CO CO97049501A patent/CO4920240A1/es unknown
- 1997-08-27 AR ARP970103902A patent/AR009457A1/es unknown
- 1997-08-28 ID IDP972993A patent/ID18416A/id unknown
- 1997-08-28 PE PE1997000767A patent/PE2599A1/es not_active Application Discontinuation
-
1999
- 1999-02-18 NO NO19990759A patent/NO314934B1/no not_active IP Right Cessation
-
2000
- 2000-03-01 US US09/516,726 patent/US6399598B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AR009457A1 (es) | 2000-04-26 |
| JP3347331B2 (ja) | 2002-11-20 |
| DE69716615T2 (de) | 2003-06-18 |
| HUP0000210A2 (hu) | 2001-04-28 |
| AU734834B2 (en) | 2001-06-21 |
| WO1998008823A1 (en) | 1998-03-05 |
| DK0923561T3 (da) | 2003-02-24 |
| TR199900382T2 (xx) | 1999-05-21 |
| DE69716615D1 (de) | 2002-11-28 |
| ATE226573T1 (de) | 2002-11-15 |
| KR20000035920A (ko) | 2000-06-26 |
| SK25799A3 (en) | 1999-12-10 |
| US6121258A (en) | 2000-09-19 |
| US6399598B1 (en) | 2002-06-04 |
| EP0923561B1 (de) | 2002-10-23 |
| NO990759L (no) | 1999-04-27 |
| CZ62699A3 (cs) | 1999-07-14 |
| CN1228772A (zh) | 1999-09-15 |
| JP2000516953A (ja) | 2000-12-19 |
| IL128664A (en) | 2003-07-06 |
| ZA977696B (en) | 1998-02-23 |
| PL331795A1 (en) | 1999-08-02 |
| CO4920240A1 (es) | 2000-05-29 |
| NO990759D0 (no) | 1999-02-18 |
| CA2263917A1 (en) | 1998-03-05 |
| IL128664A0 (en) | 2000-01-31 |
| NZ334254A (en) | 2000-11-24 |
| NO314934B1 (no) | 2003-06-16 |
| PE2599A1 (es) | 1999-03-03 |
| AU4153097A (en) | 1998-03-19 |
| EP0923561A1 (de) | 1999-06-23 |
| BR9712085A (pt) | 2000-10-24 |
| HUP0000210A3 (en) | 2001-07-30 |
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|---|---|---|
| ID19198A (id) | Inhibitor metaloprotease heterosiklik | |
| ID18416A (id) | Inhibitor metaloprotease diheterosiklik | |
| ID18141A (id) | Inhibitor metaloprotease 1,3-diheterosiklik | |
| FI963597L (fi) | Isoprenyylitransferaasi-inhibiittoreita | |
| NO972930D0 (no) | Fibronectin-adhesjonsinhibitorer | |
| FI972160A0 (fi) | Matriisimetalloproteaasi-inhibiittorit | |
| DE69736445D1 (de) | Refluxinhibitoren | |
| FI951553L (fi) | 1H-indoli-glyoksyyliamidi-sPLA2-inhibiittoreita | |
| DK1027332T3 (da) | Hidtil ukendte lactametalloproteaseinhibitorer | |
| DK0958287T3 (da) | Sulfamidmetalloprotease-inhibitorer | |
| ID27574A (id) | Inhibitor enzim | |
| ATE239755T1 (de) | Thrombin inhibitoren | |
| DK0956294T3 (da) | Thrombininhibitorer | |
| PT927183E (pt) | Inibidores espirociclicos de metaloproteases | |
| NO20003256D0 (no) | ACE inhibitor-MMP inhibitor kombinasjoner | |
| BR9707086A (pt) | Inibidores de proteinase aspartila | |
| DE69736109D1 (de) | Differenzierungsinhibitor | |
| PT948483E (pt) | Inibidores da farnesil-transferase | |
| DE69526475D1 (de) | 5-Alphareduktase-Inhibitoren | |
| ATE252547T1 (de) | Matrixmetalloproteinaseinhibitoren | |
| NO983283D0 (no) | Hydrokamsyre-baserte Kollagenase-inhibitorer | |
| ATE282629T1 (de) | Thrombininhibitoren | |
| DE69720957T2 (de) | Ace-hemmer | |
| BR9610514A (pt) | Inibidores cicloantihelmínticos | |
| EP1007548A4 (de) | Tsetse-thrombin inhibitor |