ID21878A - Turunan-turunan tiazola, proses pembuatan pemakaian, dan metodenya yang menghambat pengikatan protein-protein adhesif - Google Patents

Turunan-turunan tiazola, proses pembuatan pemakaian, dan metodenya yang menghambat pengikatan protein-protein adhesif

Info

Publication number
ID21878A
ID21878A IDP990002A ID990002A ID21878A ID 21878 A ID21878 A ID 21878A ID P990002 A IDP990002 A ID P990002A ID 990002 A ID990002 A ID 990002A ID 21878 A ID21878 A ID 21878A
Authority
ID
Indonesia
Prior art keywords
tiazola
usage
decreases
methods
manufacturing process
Prior art date
Application number
IDP990002A
Other languages
English (en)
Inventor
Leo Alig
Albrecht Edenhoeer
Kurt Hilperi
Thomas Weller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ID21878A publication Critical patent/ID21878A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IDP990002A 1998-01-02 1999-01-04 Turunan-turunan tiazola, proses pembuatan pemakaian, dan metodenya yang menghambat pengikatan protein-protein adhesif ID21878A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98100007 1998-01-02

Publications (1)

Publication Number Publication Date
ID21878A true ID21878A (id) 1999-08-05

Family

ID=8231230

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP990002A ID21878A (id) 1998-01-02 1999-01-04 Turunan-turunan tiazola, proses pembuatan pemakaian, dan metodenya yang menghambat pengikatan protein-protein adhesif

Country Status (28)

Country Link
US (1) US6001855A (id)
JP (1) JP3154982B2 (id)
KR (1) KR100312900B1 (id)
CN (1) CN1098849C (id)
AR (1) AR014211A1 (id)
AT (1) ATE217621T1 (id)
AU (1) AU718659B2 (id)
BR (1) BR9805750A (id)
CA (1) CA2257322C (id)
CO (1) CO4990935A1 (id)
DE (1) DE69805392T2 (id)
DK (1) DK0928793T3 (id)
ES (1) ES2176895T3 (id)
HR (1) HRP980644B1 (id)
HU (1) HUP9803041A3 (id)
ID (1) ID21878A (id)
IL (1) IL127784A (id)
MA (1) MA26590A1 (id)
NO (1) NO312134B1 (id)
PE (1) PE20000116A1 (id)
PL (1) PL330620A1 (id)
PT (1) PT928793E (id)
RU (1) RU2166503C2 (id)
SG (1) SG72911A1 (id)
TR (1) TR199802766A2 (id)
UY (1) UY25335A1 (id)
YU (1) YU60998A (id)
ZA (1) ZA9811923B (id)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0104202A3 (en) 1998-10-22 2003-12-29 Hoffmann La Roche Thiazole-derivatives, process for their preparation and pharmaceutical compositions containing them
JP4517454B2 (ja) * 2000-06-01 2010-08-04 宇部興産株式会社 ４−（１−フルオロエチル）チアゾール−５−カルボン酸アミド誘導体及び農園芸用の有害生物防除剤
US6420566B2 (en) * 2000-06-09 2002-07-16 Aventis Pharma S.A. Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof
US6451821B1 (en) * 2000-06-09 2002-09-17 Aventis Pharma S.A. Use of 2-aminothiazoline derivatives as inhibitors of inducible no-synthase
WO2017095991A1 (en) * 2015-12-04 2017-06-08 Janssen Biotech, Inc. Treatment of retinal degeneration using progenitor cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2138803B (en) * 1983-04-26 1986-06-18 Shionogi & Co 2-guanidino-4-hydroxymethylthiazole and derivatives thereof
GB8714920D0 (en) * 1987-06-25 1987-07-29 Shell Int Research Thiazole derivatives
IL95548A0 (en) * 1989-09-15 1991-06-30 Fujisawa Pharmaceutical Co Thiazole derivatives,processes for the preparation thereof and pharmaceutical composition containing the same
TW201303B (id) * 1990-07-05 1993-03-01 Hoffmann La Roche
JPH0867676A (ja) * 1994-03-30 1996-03-12 Eisai Kagaku Kk 保護アミノチアゾリル酢酸誘導体
IL123164A (en) * 1995-08-30 2001-03-19 Searle & Co Meta-guanidine urea thiourea or azacyclic amino benzoic acid derivatives and pharmaceutical compositions containing them
AU713676B2 (en) * 1996-01-16 1999-12-09 Merck & Co., Inc. Integrin receptor antagonists
KR19980071340A (ko) * 1997-02-13 1998-10-26 미우라 유이찌 클로로아세틸아미노티아졸아세트산 유도체의 제조 방법
WO1998054164A1 (en) * 1997-05-30 1998-12-03 Takeda Chemical Industries, Ltd. Sulfonamide derivatives, their production and use

Also Published As

Publication number Publication date
TR199802766A3 (tr) 1999-07-21
TR199802766A2 (xx) 1999-07-21
PE20000116A1 (es) 2000-02-11
PT928793E (pt) 2002-10-31
CO4990935A1 (es) 2000-12-26
HUP9803041A3 (en) 2001-04-28
CN1098849C (zh) 2003-01-15
AU718659B2 (en) 2000-04-20
MA26590A1 (fr) 2004-12-20
NO312134B1 (no) 2002-03-25
PL330620A1 (en) 1999-07-05
JP2000053678A (ja) 2000-02-22
US6001855A (en) 1999-12-14
ZA9811923B (en) 2000-06-29
KR19990066903A (ko) 1999-08-16
RU2166503C2 (ru) 2001-05-10
AR014211A1 (es) 2001-02-07
HU9803041D0 (en) 1999-02-01
NO986160L (no) 1999-07-05
JP3154982B2 (ja) 2001-04-09
YU60998A (sh) 2001-12-26
BR9805750A (pt) 2001-04-24
DE69805392D1 (de) 2002-06-20
HK1021733A1 (en) 2000-06-30
DE69805392T2 (de) 2002-12-19
KR100312900B1 (ko) 2002-01-17
HRP980644A2 (en) 1999-10-31
CA2257322C (en) 2003-11-04
IL127784A0 (en) 1999-10-28
AU9614598A (en) 1999-07-22
NO986160D0 (no) 1998-12-28
CA2257322A1 (en) 1999-07-02
IL127784A (en) 2001-09-13
UY25335A1 (es) 2001-01-31
CN1227225A (zh) 1999-09-01
HRP980644B1 (en) 2003-08-31
DK0928793T3 (da) 2002-09-09
ATE217621T1 (de) 2002-06-15
ES2176895T3 (es) 2002-12-01
SG72911A1 (en) 2000-05-23
HUP9803041A2 (hu) 2000-04-28

Similar Documents

Publication Publication Date Title
ID21361A (id) Baterai dan metode pembuatannya
ID18046A (id) Senyawa siklik campuran, pembuatan dan penngunaannya.
ID19824A (id) Turunan-turunan ditiolan, pembuatannya dan pengaruh terapinya
DE69835106D1 (de) Eingebetteter logischer Analysator
EE05538B1 (et) Interleukiin-18 seostuvad valgud, nende valmistamine ja kasutamine
ID19290A (id) Turunan-turunan propiofenon dan proses pembuatannya
NO2010022I2 (no) Denosumab
ID24929A (id) Turunan 2-aril-8-oksodihidropurin, proses pembuatannya, komposisi farmasinya yang mengandungnya, dan senyawa antaranya
ID23985A (id) Baterai dan metode pembuatannya
ID28787A (id) 2-fenilbenzimidazol tersubstitusi, pembuatannya dan penggunaannya
EP1003689A4 (en) GETTER MATERIALS FOR AMMONIA CRACKING
DK0954410T3 (da) Fremstilling afämànstrede slibeoverflader
IL200404A0 (en) 191P4D12(b) PROTEINS, POLYNUCLEOTIDES ENCODING THE SAME; ANTIBODIES BINDING THERETO AND USES THEREOF
ID28728A (id) Komposisi dan proses pengkrepan
ID28997A (id) Kedok sekali pakai, dan proses pembuatannya
AU1220001A (en) Novel proteins and polynucleotides encoding them
ID30506A (id) Proses pengembangan ko-produksi 6-aminokapronitril dan heksametilenadiamino
ID26074A (id) Monofilamen dan proses produksinya
TR199802394A3 (tr) Proteinleri stabilize etmek için gelistirilmis proses.
ID26902A (id) Proses dan radas untuk pembuatan melamina
ID24600A (id) Proses pembuatan poliol-poliol polieter dan poliol yang dibuat bersamaan
ID23304A (id) Turunan-turunan diaza-spiro [3,5] nonana, proses pembuatan dan penggunaannya
ID22877A (id) Proses pembuatan diena terkonjugasi yang dimurnikan
ID26344A (id) Pakaian atas sekali pakai dan proses pembuatannya
NO983166L (no) Ny fremstillingsprosess