ID21927A - Asam aminoalkanafosfonat tersubstitusi - Google Patents

Asam aminoalkanafosfonat tersubstitusi

Info

Publication number
ID21927A
ID21927A IDW990225A ID990225A ID21927A ID 21927 A ID21927 A ID 21927A ID W990225 A IDW990225 A ID W990225A ID 990225 A ID990225 A ID 990225A ID 21927 A ID21927 A ID 21927A
Authority
ID
Indonesia
Prior art keywords
pct
aliphatic
araliphatic
date apr
cycloaliphatic
Prior art date
Application number
IDW990225A
Other languages
English (en)
Inventor
Pierre Acklin
Hans Allgeter
Yves Auberson
Silvio Ofner
Siem Jacob Veenstra
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ID21927A publication Critical patent/ID21927A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994—Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW990225A 1996-10-24 1997-10-22 Asam aminoalkanafosfonat tersubstitusi ID21927A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH262196 1996-10-24

Publications (1)

Publication Number Publication Date
ID21927A true ID21927A (id) 1999-08-12

Family

ID=4237878

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990225A ID21927A (id) 1996-10-24 1997-10-22 Asam aminoalkanafosfonat tersubstitusi

Country Status (23)

Country Link
US (1) US6117873A (id)
EP (1) EP0934326B1 (id)
JP (1) JP3908790B2 (id)
KR (1) KR20000052747A (id)
CN (1) CN1092202C (id)
AT (1) ATE325128T1 (id)
AU (1) AU5188598A (id)
BR (1) BR9713489A (id)
CA (1) CA2269807C (id)
CZ (1) CZ141399A3 (id)
DE (1) DE59712642D1 (id)
ES (1) ES2264171T3 (id)
HU (1) HUP0000383A3 (id)
ID (1) ID21927A (id)
IL (1) IL129394A (id)
NO (1) NO991902L (id)
NZ (1) NZ334891A (id)
PL (1) PL192286B1 (id)
PT (1) PT934326E (id)
RU (1) RU2181362C2 (id)
SK (1) SK282548B6 (id)
TR (1) TR199900897T2 (id)
WO (1) WO1998017672A1 (id)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2645199A (en) * 1998-11-18 2000-06-05 Viktor Veniaminovich Tets Dialkyl-1-aryl-1-(2,4-dioxo-5-amino-1,3-pyrimidin-5-yl)methy lphosphonates
US7205404B1 (en) * 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
JP2004513891A (ja) * 2000-09-27 2004-05-13 アイレックス　オンコロジー　リサーチ　エス．エイ． α−置換β−アミノエチルホスホネート
GB0025849D0 (en) 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
US6492517B1 (en) * 2001-07-19 2002-12-10 Air Products And Chemicals, Inc. Method for preparing halomethyl heterocyclic compounds
TW200403066A (en) * 2002-04-30 2004-03-01 Novartis Ag New uses of substituted aminoalkanephosphonic acids
GB0307860D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
GB0310868D0 (en) * 2003-05-12 2003-06-18 Novartis Ag Organic compounds
GB0324541D0 (en) * 2003-10-21 2003-11-26 Novartis Ag Organic compounds
GB0324542D0 (en) * 2003-10-21 2003-11-26 Novartis Ag Organic compounds
GB0325175D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325173D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325172D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325390D0 (en) * 2003-10-30 2003-12-03 Novartis Ag Organic compounds
US7829552B2 (en) * 2003-11-19 2010-11-09 Metabasis Therapeutics, Inc. Phosphorus-containing thyromimetics
GB0405034D0 (en) * 2004-03-05 2004-04-07 Novartis Ag Organic compounds
CA2603258A1 (en) * 2005-04-04 2006-10-12 Eisai Co., Ltd. Dihydropyridine compounds and compositions for headaches
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
JP2008542301A (ja) 2005-05-26 2008-11-27 メタバシス・セラピューティクス・インコーポレイテッド 脂肪性肝疾患の処置のための甲状腺ホルモン様薬剤
MX2007014501A (es) * 2005-05-26 2008-02-07 Metabasis Therapeutics Inc Tiromimeticos novedosos que contienen acido fosfinico.
US20080108622A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
US20080108603A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
GB0708507D0 (en) * 2007-05-02 2007-06-13 Queen Mary & Westfield College Substituted phosphonates and their use
US8349828B2 (en) 2008-02-20 2013-01-08 Actelion Pharmaceuticals Ltd. Azatricyclic antibiotic compounds
EP2326619B1 (en) 2008-08-01 2019-02-27 Bioxiness Pharmaceuticals, Inc. Methionine analogs and methods of using same
PT2344495E (pt) 2008-10-07 2015-04-01 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
WO2010101967A2 (en) * 2009-03-04 2010-09-10 Idenix Pharmaceuticals, Inc. Phosphothiophene and phosphothiazole hcv polymerase inhibitors
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
JP2017520545A (ja) 2014-07-02 2017-07-27 リガンド・ファーマシューティカルズ・インコーポレイテッド プロドラッグ化合物およびそれらの使用
EP3541395A4 (en) 2016-11-21 2020-07-01 Viking Therapeutics, Inc. GLYCOGENOSIS TREATMENT METHODS
EP3634426A4 (en) 2017-06-05 2021-04-07 Viking Therapeutics, Inc. COMPOSITIONS FOR TREATMENT OF FIBROSE
CA3087932A1 (en) 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof
CA3094167A1 (en) 2018-03-22 2019-09-26 Viking Therapeutics, Inc. Crystalline forms and methods of producing crystalline forms of a compound
WO2020117962A1 (en) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation
CN114409890A (zh) * 2022-02-28 2022-04-29 中国科学院长春应用化学研究所 一种氨基功能化的聚乙二醇衍生物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
CA2095444C (en) * 1990-11-06 2001-06-19 Shuichi Sakamoto Fused pyrazine derivatives
US5118675A (en) * 1991-02-15 1992-06-02 American Home Products Corporation Quinoxaline phosphono-amino acids
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
ES2313714T3 (es) * 1992-06-22 2009-03-01 The Regents Of The University Of California Antagonistas de receptores de glicina y uso de los mismos.
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
PL324340A1 (en) * 1995-07-10 1998-05-25 Ciba Geigy Ag Novel quinoxalinophosphonic and quinoxalinoalkanophosphonic acids
MY132385A (en) * 1995-08-31 2007-10-31 Novartis Ag 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives

Also Published As

Publication number Publication date
NO991902L (no) 1999-06-21
ES2264171T3 (es) 2006-12-16
EP0934326B1 (de) 2006-05-03
EP0934326A1 (de) 1999-08-11
IL129394A0 (en) 2000-02-17
JP2001502681A (ja) 2001-02-27
IL129394A (en) 2002-05-23
DE59712642D1 (de) 2006-06-08
WO1998017672A1 (de) 1998-04-30
CN1092202C (zh) 2002-10-09
JP3908790B2 (ja) 2007-04-25
CA2269807A1 (en) 1998-04-30
TR199900897T2 (xx) 1999-07-21
HUP0000383A3 (en) 2003-01-28
HUP0000383A2 (hu) 2001-05-28
SK282548B6 (sk) 2002-10-08
CZ141399A3 (cs) 1999-07-14
US6117873A (en) 2000-09-12
CA2269807C (en) 2007-04-10
CN1234037A (zh) 1999-11-03
SK52399A3 (en) 2000-04-10
KR20000052747A (ko) 2000-08-25
PL332775A1 (en) 1999-10-11
AU5188598A (en) 1998-05-15
ATE325128T1 (de) 2006-06-15
BR9713489A (pt) 2000-02-29
NZ334891A (en) 2001-04-27
RU2181362C2 (ru) 2002-04-20
PT934326E (pt) 2006-08-31
NO991902D0 (no) 1999-04-21
PL192286B1 (pl) 2006-09-29

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