ID22064A - Bahan kristal cefditoren pivoksil dan pembuatannya - Google Patents

Bahan kristal cefditoren pivoksil dan pembuatannya

Info

Publication number
ID22064A
ID22064A IDW990100A ID990100A ID22064A ID 22064 A ID22064 A ID 22064A ID W990100 A IDW990100 A ID W990100A ID 990100 A ID990100 A ID 990100A ID 22064 A ID22064 A ID 22064A
Authority
ID
Indonesia
Prior art keywords
crystal
pivoxic
production
materials
crystal materials
Prior art date
Application number
IDW990100A
Other languages
English (en)
Inventor
Kiyoshi Yasui
Masahiro Onodera
Masamichi Sukegawa
Tatsuo Watanabe
Yuichi Yamamoto
Yasushi Murai
Katsuhara Iinuma
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of ID22064A publication Critical patent/ID22064A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
IDW990100A 1996-09-20 1997-09-19 Bahan kristal cefditoren pivoksil dan pembuatannya ID22064A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24956196 1996-09-20

Publications (1)

Publication Number Publication Date
ID22064A true ID22064A (id) 1999-08-26

Family

ID=17194838

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990100A ID22064A (id) 1996-09-20 1997-09-19 Bahan kristal cefditoren pivoksil dan pembuatannya

Country Status (25)

Country Link
US (2) US6294669B1 (id)
EP (1) EP0937083B1 (id)
JP (1) JP3403206B2 (id)
KR (1) KR100441907B1 (id)
CN (1) CN1116299C (id)
AR (1) AR008483A1 (id)
AT (1) ATE238310T1 (id)
AU (1) AU714735B2 (id)
BR (1) BR9712072A (id)
CA (1) CA2265686C (id)
CZ (1) CZ295199B6 (id)
DE (1) DE69721290T2 (id)
EA (1) EA001526B1 (id)
ES (1) ES2198593T3 (id)
HU (1) HU224196B1 (id)
ID (1) ID22064A (id)
IL (1) IL129016A (id)
NZ (1) NZ334883A (id)
PL (1) PL189548B1 (id)
PT (1) PT937083E (id)
RO (1) RO120196B1 (id)
SK (1) SK284973B6 (id)
TR (1) TR199900614T2 (id)
UA (1) UA55426C2 (id)
WO (1) WO1998012200A1 (id)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU224196B1 (hu) * 1996-09-20 2005-06-28 Meiji Seika Kaisha Ltd. Cefditoren-pivoxil kristályos formája, és eljárás annak előállítására
PT1051978E (pt) 1998-01-07 2012-11-20 Meiji Seika Pharma Co Ltd Composições de cefalosporina amorfa cristalograficamente estável e processo para a sua produção
AR025976A1 (es) 1999-10-08 2002-12-26 Affinium Pharm Inc Inhibidores de fab i.
HU226640B1 (en) * 1999-10-18 2009-05-28 Egis Gyogyszergyar Nyilvanosan Process for producing amorphous atorvastatin calcium salt
JP2001131071A (ja) * 1999-10-29 2001-05-15 Meiji Seika Kaisha Ltd 非晶質および非晶質を含有する医薬組成物
CA2444597A1 (en) * 2001-04-06 2002-10-06 Affinium Pharmaceuticals, Inc. Fab i inhibitors
ES2361739T3 (es) * 2002-08-16 2011-06-21 Immunogen, Inc. Reticulantes con elevada reactividad y solubilidad y su uso en la preparación de conjugados para el suministro dirigido de fármacos de molécula pequeña.
EP1555024B1 (en) * 2002-10-02 2010-09-29 Meiji Seika Kaisha Ltd. Antibacterial medicinal composition of enhanced oral absorptivity
WO2004046154A1 (en) * 2002-11-15 2004-06-03 Orchid Chemicals & Pharmaceuticals Ltd Novel amorphous hydrate of a cephalosporin antibiotic
CA2508792C (en) 2002-12-06 2013-02-05 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) * 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
JP5230934B2 (ja) * 2003-03-27 2013-07-10 バジリア ファルマスーチカ アーゲー 結晶形態のセファロスポリン
US8088387B2 (en) * 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
WO2005016936A2 (en) * 2003-08-14 2005-02-24 Ranbaxy Laboratories Limited Process for selective preparation of z-isomer of cefditoren and pharmaceutically acceptable salts and esters thereof
PT1671635E (pt) 2003-10-08 2012-01-17 Meiji Seika Pharma Co Ltd Composição de antibiótico amorfo contendo cefditoreno pivoxil
JP2007510709A (ja) * 2003-11-07 2007-04-26 ランバクシー ラボラトリーズ リミテッド 高純度３−（２−置換ビニル）セファロスポリンの製法
JP2005162696A (ja) * 2003-12-04 2005-06-23 Nichiko Pharmaceutical Co Ltd 溶出性に優れたセフジトレンピボキシル製剤
CA2568914C (en) * 2004-06-04 2013-09-24 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
WO2006024900A1 (en) * 2004-08-31 2006-03-09 Ranbaxy Laboratories Limited Highly pure cefditoren pivoxil
EP1973902A2 (en) * 2005-12-05 2008-10-01 Affinium Pharmaceuticals, Inc. 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
US20080069879A1 (en) * 2006-05-02 2008-03-20 Ravishekhar Bhiwgade Stable solid dosage form containing amorphous cefditoren pivoxil and process for preparation thereof
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
US8263613B2 (en) * 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
EP2520578A1 (en) 2011-05-06 2012-11-07 Lupin Limited Process for purification of cephalosporins
CN103421025B (zh) * 2012-05-21 2016-05-11 上海医药工业研究院 制备7α-甲氧基头孢菌素C的方法
SMT201900411T1 (it) 2012-06-19 2019-09-09 Debiopharm Int Sa Derivati di profaramci di (e)-n-metil-n-((3-metilbenzofuran-2-il)metil -3-(7-osso-5,6,7,8-tetraidro-1,8-naftiridin-3-il)acrilammide
KR101561963B1 (ko) * 2013-05-23 2015-10-22 영진약품공업 주식회사 세프디토렌 피복실의 신규 결정 형태 및 이의 제조 방법
CN103665002B (zh) * 2013-12-18 2016-02-03 成都医路康医学技术服务有限公司 一种头孢妥仑匹酯的制备方法
WO2016114727A1 (en) 2015-01-16 2016-07-21 Öğün Yusuf Toktamiş Cefditoren pivoxil compositions with improved stability and production methods thereof
BR122023021456A2 (pt) 2016-02-26 2024-02-20 Debiopharm International S.A. Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
FI3923914T3 (fi) 2019-02-14 2023-04-27 Debiopharm Int Sa Afabisiiniformulaatio, menetelmä sen valmistamiseksi
MA56184A (fr) 2019-06-14 2022-04-20 Debiopharm Int Sa Afabicine pour utilisation dans le traitement d'infections bactériennes impliquant un biofilm

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
US5827845A (en) * 1993-09-29 1998-10-27 Meiji Seika Kaisha, Ltd. Cephalosporin derivative
EP0658558B1 (en) * 1993-11-17 2001-01-24 Biochemie Gesellschaft M.B.H. Separation of cephalosporin isomers
HU224196B1 (hu) * 1996-09-20 2005-06-28 Meiji Seika Kaisha Ltd. Cefditoren-pivoxil kristályos formája, és eljárás annak előállítására

Also Published As

Publication number Publication date
EA001526B1 (ru) 2001-04-23
JP2001500521A (ja) 2001-01-16
HU224196B1 (hu) 2005-06-28
TR199900614T2 (xx) 1999-06-21
EP0937083B1 (en) 2003-04-23
US20020002279A1 (en) 2002-01-03
HUP9903454A3 (en) 2001-04-28
PT937083E (pt) 2003-08-29
CN1116299C (zh) 2003-07-30
CA2265686C (en) 2006-10-31
AU4222297A (en) 1998-04-14
DE69721290D1 (de) 2003-05-28
PL189548B1 (pl) 2005-08-31
AU714735B2 (en) 2000-01-13
NZ334883A (en) 2000-09-29
KR100441907B1 (ko) 2004-07-27
EP0937083A1 (en) 1999-08-25
US6294669B1 (en) 2001-09-25
SK284973B6 (sk) 2006-03-02
SK35499A3 (en) 2000-03-13
KR20000048496A (ko) 2000-07-25
IL129016A (en) 2003-01-12
WO1998012200A1 (en) 1998-03-26
CA2265686A1 (en) 1998-03-26
BR9712072A (pt) 1999-08-24
ATE238310T1 (de) 2003-05-15
CZ97599A3 (cs) 1999-08-11
DE69721290T2 (de) 2004-01-22
PL332314A1 (en) 1999-08-30
AR008483A1 (es) 2000-01-19
CZ295199B6 (cs) 2005-06-15
US6441162B2 (en) 2002-08-27
HK1022912A1 (en) 2000-08-25
IL129016A0 (en) 2000-02-17
EA199900311A1 (ru) 1999-10-28
HUP9903454A2 (hu) 2000-03-28
UA55426C2 (uk) 2003-04-15
CN1234036A (zh) 1999-11-03
ES2198593T3 (es) 2004-02-01
RO120196B1 (ro) 2005-10-28
JP3403206B2 (ja) 2003-05-06

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