ID22876A - QUINOLIN-4-CARBOXAMIDE DEGREE AS RECIPIENT OF NK-2 AND NK-3 ANTAGONISTS - Google Patents

QUINOLIN-4-CARBOXAMIDE DEGREE AS RECIPIENT OF NK-2 AND NK-3 ANTAGONISTS

Info

Publication number
ID22876A
ID22876A IDW991432A ID991432A ID22876A ID 22876 A ID22876 A ID 22876A ID W991432 A IDW991432 A ID W991432A ID 991432 A ID991432 A ID 991432A ID 22876 A ID22876 A ID 22876A
Authority
ID
Indonesia
Prior art keywords
quinolin
carboxamide
antagonists
recipient
degree
Prior art date
Application number
IDW991432A
Other languages
Indonesian (id)
Inventor
Giuseppe Arnaldo Mari Giardina
Mario Grugni
Devide Graziani
Luca Francesco Raveglia
Original Assignee
Smithkline Beecham Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9710750.2A external-priority patent/GB9710750D0/en
Priority claimed from IT002354 external-priority patent/IT1295358B1/en
Priority claimed from ITMI972775 external-priority patent/IT1296976B1/en
Application filed by Smithkline Beecham Spa filed Critical Smithkline Beecham Spa
Publication of ID22876A publication Critical patent/ID22876A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IDW991432A 1997-05-23 1998-05-18 QUINOLIN-4-CARBOXAMIDE DEGREE AS RECIPIENT OF NK-2 AND NK-3 ANTAGONISTS ID22876A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9710750.2A GB9710750D0 (en) 1997-05-23 1997-05-23 Novel compounds
IT002354 IT1295358B1 (en) 1997-10-17 1997-10-17 New quinoline arylmethylcarboxamide are NK-2 and NK-3 receptor antagonists - useful for treating asthma, arthritis, dermatitis, organ transplant, anxiety, depression, angina, pain, Alzheimer's disease
ITMI972775 IT1296976B1 (en) 1997-12-16 1997-12-16 New quinoline arylmethylcarboxamide are NK-2 and NK-3 receptor antagonists - useful for treating asthma, arthritis, dermatitis, organ transplant, anxiety, depression, angina, pain, Alzheimer's disease

Publications (1)

Publication Number Publication Date
ID22876A true ID22876A (en) 1999-12-16

Family

ID=27268859

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW991432A ID22876A (en) 1997-05-23 1998-05-18 QUINOLIN-4-CARBOXAMIDE DEGREE AS RECIPIENT OF NK-2 AND NK-3 ANTAGONISTS

Country Status (26)

Country Link
EP (1) EP0983262B1 (en)
JP (1) JP2002500645A (en)
CN (1) CN1264378A (en)
AP (1) AP9901695A0 (en)
AR (1) AR012732A1 (en)
AT (1) ATE244711T1 (en)
AU (1) AU8209898A (en)
BG (1) BG104009A (en)
BR (1) BR9809652A (en)
CA (1) CA2291111A1 (en)
CO (1) CO4950515A1 (en)
DE (1) DE69816290T2 (en)
DZ (1) DZ2498A1 (en)
EA (1) EA199901062A1 (en)
ES (1) ES2201509T3 (en)
HU (1) HUP0002300A3 (en)
ID (1) ID22876A (en)
IL (1) IL133036A0 (en)
MA (1) MA26501A1 (en)
NO (1) NO995711L (en)
OA (1) OA11515A (en)
PE (1) PE75199A1 (en)
PL (1) PL336942A1 (en)
SK (1) SK159299A3 (en)
TR (1) TR199902883T2 (en)
WO (1) WO1998052942A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780875B2 (en) * 1998-11-20 2004-08-24 Smithkline Beecham S.P.A. Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists
JP2002530377A (en) * 1998-11-20 2002-09-17 スミスクライン・ビーチャム・ソシエタ・ペル・アチオニ Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists
GB9825554D0 (en) * 1998-11-20 1999-01-13 Smithkline Beecham Spa Novel Compounds
ATE247652T1 (en) 1999-03-29 2003-09-15 Neurogen Corp 4-SUBSTITUTED QUINOLINE DERIVATIVES AS NK-3 AND/OR GABA(A) RECEPTOR LIGANDS
WO2000064877A1 (en) * 1999-04-26 2000-11-02 Neurogen Corporation 2-aminoquinolinecarboxamides: neurokinin receptor ligands
WO2002013825A1 (en) * 2000-08-11 2002-02-21 Smithkline Beecham P.L.C. Novel pharmaceutical use of quinnoline derivatives
EP1334089A1 (en) * 2000-11-13 2003-08-13 GlaxoSmithKline S.p.A. Quinoline derivatives as nk-3 and nk-2 antagonists
WO2002044165A1 (en) * 2000-11-28 2002-06-06 Glaxosmithkline Spa Quinoline derivatives as nk-3 antagonists
GB0028964D0 (en) * 2000-11-28 2001-01-10 Smithkline Beecham Spa Novel compounds
US6540733B2 (en) 2000-12-29 2003-04-01 Corazon Technologies, Inc. Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion
EP1385839B1 (en) * 2001-04-11 2006-02-22 GlaxoSmithKline S.p.A. 3-substituted quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists
GB0109122D0 (en) * 2001-04-11 2001-05-30 Smithkline Beecham Spa Novel compounds
MY134211A (en) * 2001-05-18 2007-11-30 Smithkline Beecham Corp Novel use
GB0425075D0 (en) * 2004-11-12 2004-12-15 Smithkline Beecham Corp Novel compounds
GB0425077D0 (en) * 2004-11-12 2004-12-15 Smithkline Beecham Corp Novel compounds
GB0425076D0 (en) * 2004-11-12 2004-12-15 Smithkline Beecham Corp Novel compounds
CA2611060A1 (en) * 2005-06-03 2006-12-07 R. Thomas Simpson Quinoline derivatives as nk3 antagonists
GB0515580D0 (en) 2005-07-29 2005-09-07 Merck Sharp & Dohme Therapeutic compounds
AR057130A1 (en) 2005-09-21 2007-11-14 Astrazeneca Ab ALKYL SULFOXIDE QUINOLINS AND A PHARMACEUTICAL COMPOSITION
DE202007017299U1 (en) * 2007-12-12 2009-04-23 Drebo Werkzeugfabrik Gmbh drill

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69531458T2 (en) * 1994-05-27 2004-08-05 Glaxosmithkline S.P.A. CHINOLINE DERIVATIVES AS TACHYKININ NK3 RECEPTOR ANTAGONISTS
AR004735A1 (en) * 1995-11-24 1999-03-10 Smithkline Beecham Spa CHINOLEIN 4-AMIDO SUBSTITUTED, A PROCEDURE FOR ITS PREPARATION, A PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM AND THE USE OF THE SAME FOR THE PREPARATION OF A MEDICINAL PRODUCT.

Also Published As

Publication number Publication date
EP0983262A1 (en) 2000-03-08
HUP0002300A3 (en) 2002-01-28
BR9809652A (en) 2001-09-11
TR199902883T2 (en) 2000-05-22
IL133036A0 (en) 2001-03-19
EA199901062A1 (en) 2000-08-28
CA2291111A1 (en) 1998-11-26
DE69816290D1 (en) 2003-08-14
AP9901695A0 (en) 1999-12-31
HUP0002300A2 (en) 2001-06-28
ES2201509T3 (en) 2004-03-16
CO4950515A1 (en) 2000-09-01
SK159299A3 (en) 2000-06-12
OA11515A (en) 2004-02-04
JP2002500645A (en) 2002-01-08
MA26501A1 (en) 2004-12-20
AR012732A1 (en) 2000-11-08
EP0983262B1 (en) 2003-07-09
NO995711L (en) 2000-01-19
ATE244711T1 (en) 2003-07-15
NO995711D0 (en) 1999-11-22
AU8209898A (en) 1998-12-11
PE75199A1 (en) 1999-10-22
PL336942A1 (en) 2000-07-17
CN1264378A (en) 2000-08-23
DE69816290T2 (en) 2004-05-27
DZ2498A1 (en) 2003-01-25
BG104009A (en) 2000-07-31
WO1998052942A1 (en) 1998-11-26

Similar Documents

Publication Publication Date Title
ID26099A (en) AMIDA DEGREE AND NOSICEPTIN ANTAGONISTS
ID29434A (en) COMBINATIONS OF HERBISIDE AND SECURITY
ID30401A (en) INDOL DRIVES AND ITS USE AS MCP-1 ANTAGONISTS
ID27031A (en) COMPOSITION OF ENTERIC PHARMACEUTICAL PHARMACEUTICAL AND MANUFACTURE METHOD
ID19253A (en) VITRONEKTIN RECEPTOR ANTAGONISTS, ITS MANUFACTURE AND USE OF IT
NO995852D0 (en) New form of S-omeprazole
ID23575A (en) PIRAZOLOPIRIMIDINA-PIRAZOLOPIRIMIDINA AND PIRAZOLOTRIAZINA-PIRAZOLOTRIAZINA
DE69712003D1 (en) Modification of xylanase to improve thermophilicity, alkophilicity and thermostability
ID29688A (en) LIGHTS ARE SHAPED LIGHTS AND METHODS OF MAKING LIGHTS
ID29543A (en) OSAZOL AND TIAZOL SUBSTITUTES SUBSTITUTED AS τhPPAR AND αhPPAR ACTIVATORS
DE60132709D1 (en) DETERMINATION OF THE EFFECTIVE COMPOSITION OF HYDROCARBON GASES
ID22889A (en) ETHYLENA COOPOLYMER COMPOSITION AND ITS USE
ID22956A (en) SYNTHESA OF DISULFIDA AND ORGANIC POLICULFIDA
PL347721A1 (en) Quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists
ID26599A (en) TRIAZOLA AND IMIDAZOLA DOWN
ID24196A (en) COMPOSITION AND USE
PL336942A1 (en) Derivatives of quinoline-4-carboxamide as antagonists of nk-2 and nk-3 receptor
DE69903961D1 (en) MUSCARINAGONISTS AND ANTAGONISTS
ID24828A (en) PHARMACY COMPOSITIONS OF TIZOKSIANIDA AND NITAZOKSANIDA
ID19245A (en) VITRONEKTIN RECEPTOR ANTAGONISTS, THE PRODUCTION AND USE OF IT
ATE274024T1 (en) OXYGEN ABSORBING COMPOSITION AND METHOD OF APPLICATION THEREOF
ID28732A (en) COMBINATIONS OF ASOSATIVE THREATENERS AND COMPOSITION OF WATER PROTECTOR COATS
ID28025A (en) METHOD OF MAKING AMINONITRIL AND DIAMINA
ID23258A (en) WITHDRAWAL-DELIVERY AND METHODS
EP1237570A4 (en) FRAGMENTS AND ANTAGONISTS OF THE HEAT SHOCK PROTEIN 60