ID23415A - Azapeptida siklik dengan efek angiogenik - Google Patents

Azapeptida siklik dengan efek angiogenik

Info

Publication number
ID23415A
ID23415A IDW991514A ID991514A ID23415A ID 23415 A ID23415 A ID 23415A ID W991514 A IDW991514 A ID W991514A ID 991514 A ID991514 A ID 991514A ID 23415 A ID23415 A ID 23415A
Authority
ID
Indonesia
Prior art keywords
azapeptides
cycle
angiogenic effects
angiogenic
effects
Prior art date
Application number
IDW991514A
Other languages
English (en)
Inventor
Alfred Jonczyk
Simon Goodman
Horst Kessler
Jochen Wermuth
Jorg Schmitt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ID23415A publication Critical patent/ID23415A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IDW991514A 1997-07-04 1998-06-29 Azapeptida siklik dengan efek angiogenik ID23415A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19728524A DE19728524A1 (de) 1997-07-04 1997-07-04 Cyclische Azapeptide

Publications (1)

Publication Number Publication Date
ID23415A true ID23415A (id) 2000-04-20

Family

ID=7834596

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW991514A ID23415A (id) 1997-07-04 1998-06-29 Azapeptida siklik dengan efek angiogenik

Country Status (20)

Country Link
US (1) US6534478B1 (id)
EP (1) EP1001979B1 (id)
JP (1) JP2002511872A (id)
KR (1) KR20010014267A (id)
CN (1) CN1261895A (id)
AR (1) AR010924A1 (id)
AT (1) ATE297947T1 (id)
AU (1) AU733831B2 (id)
BR (1) BR9810394A (id)
CA (1) CA2297181A1 (id)
DE (2) DE19728524A1 (id)
HU (1) HUP0003357A3 (id)
ID (1) ID23415A (id)
NO (1) NO20000016D0 (id)
PL (1) PL337616A1 (id)
RU (1) RU2188205C2 (id)
SK (1) SK173599A3 (id)
TW (1) TW482768B (id)
WO (1) WO1999001472A1 (id)
ZA (1) ZA985896B (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA71608C2 (en) * 1999-03-11 2004-12-15 Merck Patent Gmbh A method for producing the cyclic pentapeptide
AU5566300A (en) 1999-06-22 2001-01-09 Takeda Chemical Industries Ltd. Acylhydrazine derivatives, process for preparing the same and use thereof
GB0217017D0 (en) * 2002-07-23 2002-08-28 Bioacta Ltd Peptide 2
WO2008033557A2 (en) * 2006-09-15 2008-03-20 Siemens Medical Solutions Usa, Inc. Click chemistry-derived cyclic peptidomimetics as integrin markers
EP2182974B1 (en) * 2007-07-27 2015-08-26 Siemens Medical Solutions USA, Inc. Cyclic azapeptides as integrin markers
WO2009134382A2 (en) 2008-04-30 2009-11-05 Siemens Medical Solutions Usa, Inc. Cyclopeptides containing rgd mimetics as imaging markers for integrins
CA2726050A1 (en) 2008-05-30 2009-12-10 Siemens Medical Solutions Usa, Inc. Achievement of high therapeutic index through molecular imaging guided targeted drug treatment
CA2665302A1 (en) * 2009-05-01 2010-11-01 Universite De Montreal Cd36 modulation and uses thereof
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
KR101335203B1 (ko) * 2010-03-26 2013-11-29 숙명여자대학교산학협력단 혈관신생촉진용 펩타이드 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them
ES2121088T3 (es) * 1992-06-04 1998-11-16 Merrell Pharma Inc Analogos de peptidos limitados conformacionalmente como agentes antiplaquetarios.
UA43823C2 (uk) * 1992-07-06 2002-01-15 Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
AU1975695A (en) * 1994-03-04 1995-09-18 Du Pont Merck Pharmaceutical Company, The Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex
US5858972A (en) * 1996-01-11 1999-01-12 La Jolla Cancer Research Foundation Antithrombotic agents and methods of use
ZA978758B (en) * 1996-10-02 1999-03-30 Du Pont Merck Pharma Technetium-99m-labeled chelator incorporated cyclic peptides that bind to the GPIIb/IIIa receptor as imaging agents
DE19653036A1 (de) * 1996-12-19 1998-06-25 Merck Patent Gmbh Cyclopeptidderivate

Also Published As

Publication number Publication date
JP2002511872A (ja) 2002-04-16
KR20010014267A (ko) 2001-02-26
AU733831B2 (en) 2001-05-24
SK173599A3 (en) 2000-06-12
EP1001979B1 (de) 2005-06-15
AU8541198A (en) 1999-01-25
RU2188205C2 (ru) 2002-08-27
NO20000016L (no) 2000-01-03
WO1999001472A1 (de) 1999-01-14
BR9810394A (pt) 2000-09-05
AR010924A1 (es) 2000-07-12
EP1001979A1 (de) 2000-05-24
ZA985896B (en) 1999-06-14
ATE297947T1 (de) 2005-07-15
NO20000016D0 (no) 2000-01-03
PL337616A1 (en) 2000-08-28
CN1261895A (zh) 2000-08-02
DE19728524A1 (de) 1999-01-07
HUP0003357A2 (hu) 2001-02-28
US6534478B1 (en) 2003-03-18
TW482768B (en) 2002-04-11
CA2297181A1 (en) 1999-01-14
HUP0003357A3 (en) 2001-12-28
DE59812870D1 (de) 2005-07-21

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