ID24101A - Turunan-turunan triazolobenzazepine trisiklik, proses pembuatan yang sama, dan zat-zat antialergi - Google Patents

Turunan-turunan triazolobenzazepine trisiklik, proses pembuatan yang sama, dan zat-zat antialergi

Info

Publication number
ID24101A
ID24101A IDW20000808A ID20000808A ID24101A ID 24101 A ID24101 A ID 24101A ID W20000808 A IDW20000808 A ID W20000808A ID 20000808 A ID20000808 A ID 20000808A ID 24101 A ID24101 A ID 24101A
Authority
ID
Indonesia
Prior art keywords
tricyclic
triazolobenzazepine
antialergy
derives
substance
Prior art date
Application number
IDW20000808A
Other languages
English (en)
Indonesian (id)
Inventor
Yasuo Ohtsuka
Toshio Nishizuka
Sohjiro Shiokawa
Seiji Tsutsumi
Mami Kawaguchi
Hideo Kitagawa
Hiromi Takata
Takashi Shishikura
Toyoaki Ishikura
Kenichi Fushihara
Yumiko Okada
Sachiko Miyamato
Maki Shiobara
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of ID24101A publication Critical patent/ID24101A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDW20000808A 1997-09-29 1998-09-29 Turunan-turunan triazolobenzazepine trisiklik, proses pembuatan yang sama, dan zat-zat antialergi ID24101A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26461197 1997-09-29
JP5206398 1998-03-04

Publications (1)

Publication Number Publication Date
ID24101A true ID24101A (id) 2000-07-06

Family

ID=26392670

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000808A ID24101A (id) 1997-09-29 1998-09-29 Turunan-turunan triazolobenzazepine trisiklik, proses pembuatan yang sama, dan zat-zat antialergi

Country Status (24)

Country Link
US (3) US6372735B1 (no)
EP (1) EP1026167B1 (no)
JP (1) JP3188482B2 (no)
KR (1) KR100389140B1 (no)
CN (2) CN1312135C (no)
AT (1) ATE233764T1 (no)
AU (1) AU744636B2 (no)
BR (1) BR9814055B1 (no)
CA (1) CA2305307C (no)
DE (1) DE69811930T2 (no)
DK (1) DK1026167T3 (no)
ES (1) ES2191963T3 (no)
HU (1) HUP0004020A3 (no)
ID (1) ID24101A (no)
IL (1) IL135303A0 (no)
NO (2) NO319542B1 (no)
NZ (1) NZ503601A (no)
PL (1) PL339544A1 (no)
PT (1) PT1026167E (no)
RU (1) RU2198885C2 (no)
SK (1) SK283869B6 (no)
TR (1) TR200000808T2 (no)
TW (1) TW510902B (no)
WO (1) WO1999016770A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4376628B2 (ja) * 2001-12-26 2009-12-02 明治製菓株式会社 三環性トリアゾロベンゾアゼピン誘導体の非晶質物質
JP4434747B2 (ja) * 2002-02-01 2010-03-17 明治製菓株式会社 １，２，３−トリアゾール化合物の製造法
ATE543497T1 (de) 2002-07-09 2012-02-15 Bristol Myers Squibb Co Substituierte heterozyklische derivate als mittel gegen diabetes und adipositas und verfahren
PL374860A1 (en) 2002-07-09 2005-11-14 Bristol-Myers Squibb Company Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
WO2004113343A1 (ja) * 2003-06-19 2004-12-29 Meiji Seika Kaisha, Ltd. 三環性トリアゾロベンゾアゼピン誘導体の新規結晶性物質
JPWO2004113451A1 (ja) * 2003-06-20 2006-08-17 明治製菓株式会社 難溶性物質と水溶性高分子との共沈物およびその製造方法
EP2261226B1 (en) 2004-05-14 2015-04-01 Millennium Pharmaceuticals, Inc. Methods for preparing aurora kinase inhibitors
MX2008011178A (es) 2006-03-02 2008-09-25 Meiji Seika Kaisha Agente profilàctico o terapèutico para enfermedad oftàlmica alèrgica o enfermedad nasal alèrgica, que comprende derivado tricìclico de triazolobenzacepina.
EP2094711B8 (de) * 2006-09-25 2018-03-28 Forschungsverbund Berlin e.V. Strukturmimetika prolinreicher peptide und ihre pharmazeutische verwendung
CL2007003244A1 (es) * 2006-11-16 2008-04-04 Millennium Pharm Inc Compuestos derivados de pirimido[5,4-d][2]benzazepina; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer.
ES2360461T3 (es) 2007-12-18 2011-06-06 Meiji Seika Kaisha Ltd. Agente preventivo o terapéutico para enfermedad inflamatoria del intestino.
JP5738196B2 (ja) 2008-12-22 2015-06-17 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． オーロラキナーゼ阻害剤および抗ｃｄ２０抗体の併用
JO3635B1 (ar) 2009-05-18 2020-08-27 Millennium Pharm Inc مركبات صيدلانية صلبة وطرق لانتاجها
US9107911B2 (en) 2010-01-07 2015-08-18 Alkermes Pharma Ireland Limited Prodrugs of heteraromatic compounds
BR112012020557A8 (pt) 2010-02-19 2018-01-02 Millennium Pharm Inc formas cristalinas de 4-{[9-cloro-7-(2-flúor-6-metoifenil)-5h-pirimido[5,4-d][2]benzazepin-2-il]amino}-2-metoxibenzoato de sódio
US20130303519A1 (en) 2012-03-20 2013-11-14 Millennium Pharmaceuticals, Inc. Methods of treating cancer using aurora kinase inhibitors
US9724354B2 (en) 2013-03-22 2017-08-08 Millennium Pharmaceuticals, Inc. Combination of catalytic mTORC1/2 inhibitors and selective inhibitors of Aurora A kinase
WO2017015316A1 (en) 2015-07-21 2017-01-26 Millennium Pharmaceuticals, Inc. Administration of aurora kinase inhibitor and chemotherapeutic agents
CN111788187A (zh) * 2017-12-29 2020-10-16 生物马林药物股份有限公司 用于疾病治疗的乙醇酸氧化酶抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1046937C (zh) 1993-04-16 1999-12-01 盐野义制药株式会社 木酚素系化合物的制备方法
DE69427023T2 (de) * 1993-12-28 2001-10-31 Meiji Seika K.K., Tokio/Tokyo Tricyclische benzazepin-und benzothiazepin derivate
CN1066148C (zh) * 1995-06-15 2001-05-23 明治制果株式会社 三环性苯并氮杂䓬化合物
CA2247453A1 (en) * 1996-03-08 1997-09-12 Joseph James Lewis Azolobenzazepine derivatives as neurologically active agents
US20070059533A1 (en) * 2005-09-12 2007-03-15 Burdette Steven R Thermal reflow of glass and fused silica body

Also Published As

Publication number Publication date
NO20043765L (no) 2000-05-18
DE69811930D1 (de) 2003-04-10
CA2305307C (en) 2004-11-30
CN1312135C (zh) 2007-04-25
AU744636B2 (en) 2002-02-28
TR200000808T2 (tr) 2000-08-21
PL339544A1 (en) 2000-12-18
DE69811930T2 (de) 2003-12-18
WO1999016770A1 (en) 1999-04-08
AU9186998A (en) 1999-04-23
NO20001500L (no) 2000-05-18
SK283869B6 (sk) 2004-03-02
US7022860B2 (en) 2006-04-04
JP3188482B2 (ja) 2001-07-16
HUP0004020A3 (en) 2002-12-28
NO319542B1 (no) 2005-08-29
RU2198885C2 (ru) 2003-02-20
PT1026167E (pt) 2003-07-31
SK4252000A3 (en) 2000-10-09
EP1026167B1 (en) 2003-03-05
HUP0004020A2 (hu) 2001-09-28
CN1523019A (zh) 2004-08-25
US6372735B1 (en) 2002-04-16
US7238812B2 (en) 2007-07-03
US20020137739A1 (en) 2002-09-26
HK1032782A1 (en) 2002-08-30
KR20010030784A (ko) 2001-04-16
BR9814055B1 (pt) 2009-05-05
CN1278262A (zh) 2000-12-27
BR9814055A (pt) 2000-09-26
TW510902B (en) 2002-11-21
NO20001500D0 (no) 2000-03-23
NZ503601A (en) 2002-02-01
ATE233764T1 (de) 2003-03-15
IL135303A0 (en) 2001-05-20
EP1026167A1 (en) 2000-08-09
CA2305307A1 (en) 1999-04-08
DK1026167T3 (da) 2003-05-26
CN1155599C (zh) 2004-06-30
US20060074074A1 (en) 2006-04-06
EP1026167A4 (en) 2001-07-11
KR100389140B1 (ko) 2003-06-25
ES2191963T3 (es) 2003-09-16

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