ID27364A - Metode untuk menghambat mrp1 - Google Patents

Metode untuk menghambat mrp1

Info

Publication number
ID27364A
ID27364A IDW20002003A ID20002003A ID27364A ID 27364 A ID27364 A ID 27364A ID W20002003 A IDW20002003 A ID W20002003A ID 20002003 A ID20002003 A ID 20002003A ID 27364 A ID27364 A ID 27364A
Authority
ID
Indonesia
Prior art keywords
inhibiting mrp1
mrp1
inhibiting
Prior art date
Application number
IDW20002003A
Other languages
English (en)
Inventor
Joseph Michael Gruber
Julian Stanley Kroin
Bryan Hurst Norman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID27364A publication Critical patent/ID27364A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Control Of The Air-Fuel Ratio Of Carburetors (AREA)
  • Magnetically Actuated Valves (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IDW20002003A 1998-04-08 1999-04-07 Metode untuk menghambat mrp1 ID27364A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8108098P 1998-04-08 1998-04-08

Publications (1)

Publication Number Publication Date
ID27364A true ID27364A (id) 2001-04-05

Family

ID=22161981

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002003A ID27364A (id) 1998-04-08 1999-04-07 Metode untuk menghambat mrp1

Country Status (18)

Country Link
US (1) US6369070B1 (id)
EP (1) EP1067928A4 (id)
JP (1) JP2002510625A (id)
KR (1) KR20010042471A (id)
CN (1) CN1304306A (id)
AU (1) AU3476999A (id)
BR (1) BR9910112A (id)
CA (1) CA2327617A1 (id)
EA (1) EA200001034A1 (id)
HR (1) HRP20000646A2 (id)
HU (1) HUP0101508A3 (id)
ID (1) ID27364A (id)
IL (1) IL138389A0 (id)
NO (1) NO20005023L (id)
PL (1) PL343313A1 (id)
SK (1) SK14982000A3 (id)
TR (1) TR200002851T2 (id)
WO (1) WO1999051228A1 (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60025744D1 (de) * 1999-10-07 2006-04-13 Lilly Co Eli Kondensierte dihydrochinolinon-derivate zur hemmung von mrp1
US6743794B2 (en) 1999-12-22 2004-06-01 Eli Lilly And Company Methods and compounds for inhibiting MRP1
WO2001046199A1 (en) * 1999-12-22 2001-06-28 Eli Lilly And Company Methods and compounds for inhibiting mrp1
WO2001096346A1 (en) * 2000-06-14 2001-12-20 Eli Lilly And Company Tricyclic compounds as mrp1-inhibitors
WO2002024705A1 (en) * 2000-09-22 2002-03-28 Eli Lilly And Company Stereoselective process for preparing cyclohexyl amine derivatives
JP2004529919A (ja) * 2001-04-09 2004-09-30 イーライ・リリー・アンド・カンパニー Ｍｒｐ１を阻害するための化合物および方法
US7101891B2 (en) 2001-04-09 2006-09-05 Eli Lilly And Company Compounds and pharmaceutical compositions for inhibiting MRP1
CA2442530A1 (en) * 2001-04-09 2002-10-17 Rosanne Bonjouklian Compounds and methods for inhibiting mrp1
EP1684762A4 (en) * 2003-11-13 2009-06-17 Ambit Biosciences Corp UREA DERIVATIVES AS MODULATORS OF KINASE
WO2005113519A1 (en) * 2004-05-14 2005-12-01 Irm Llc Compounds and compositions as ppar modulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588731A (en) * 1985-06-21 1986-05-13 Roussel Uclaf Derivatives of isoxazolo[4,5-c]quinoline(2H)-3-one and method of preparation and use as anxiolytic agents
US5744485A (en) 1994-03-25 1998-04-28 Vertex Pharmaceuticals Incorporated Carbamates and ureas as modifiers of multi-drug resistance
US5717092A (en) 1996-03-29 1998-02-10 Vertex Pharmaceuticals Inc. Compounds with improved multi-drug resistance activity

Also Published As

Publication number Publication date
TR200002851T2 (tr) 2000-12-21
HUP0101508A2 (hu) 2001-10-28
EP1067928A1 (en) 2001-01-17
US6369070B1 (en) 2002-04-09
BR9910112A (pt) 2000-12-26
HRP20000646A2 (en) 2001-06-30
AU3476999A (en) 1999-10-25
CA2327617A1 (en) 1999-10-14
JP2002510625A (ja) 2002-04-09
NO20005023D0 (no) 2000-10-05
HUP0101508A3 (en) 2002-04-29
IL138389A0 (en) 2001-10-31
SK14982000A3 (sk) 2001-05-10
PL343313A1 (en) 2001-08-13
CN1304306A (zh) 2001-07-18
WO1999051228A1 (en) 1999-10-14
EP1067928A4 (en) 2001-11-14
NO20005023L (no) 2000-12-05
KR20010042471A (ko) 2001-05-25
EA200001034A1 (ru) 2001-04-23

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