ID27364A - Metode untuk menghambat mrp1 - Google Patents

Metode untuk menghambat mrp1

Info

Publication number
ID27364A
ID27364A IDW20002003A ID20002003A ID27364A ID 27364 A ID27364 A ID 27364A ID W20002003 A IDW20002003 A ID W20002003A ID 20002003 A ID20002003 A ID 20002003A ID 27364 A ID27364 A ID 27364A
Authority
ID
Indonesia
Prior art keywords
inhibiting mrp1
mrp1
inhibiting
Prior art date
Application number
IDW20002003A
Other languages
English (en)
Inventor
Joseph Michael Gruber
Julian Stanley Kroin
Bryan Hurst Norman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID27364A publication Critical patent/ID27364A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Control Of The Air-Fuel Ratio Of Carburetors (AREA)
  • Magnetically Actuated Valves (AREA)
IDW20002003A 1998-04-08 1999-04-07 Metode untuk menghambat mrp1 ID27364A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8108098P 1998-04-08 1998-04-08

Publications (1)

Publication Number Publication Date
ID27364A true ID27364A (id) 2001-04-05

Family

ID=22161981

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002003A ID27364A (id) 1998-04-08 1999-04-07 Metode untuk menghambat mrp1

Country Status (18)

Country Link
US (1) US6369070B1 (id)
EP (1) EP1067928A4 (id)
JP (1) JP2002510625A (id)
KR (1) KR20010042471A (id)
CN (1) CN1304306A (id)
AU (1) AU3476999A (id)
BR (1) BR9910112A (id)
CA (1) CA2327617A1 (id)
EA (1) EA200001034A1 (id)
HR (1) HRP20000646A2 (id)
HU (1) HUP0101508A3 (id)
ID (1) ID27364A (id)
IL (1) IL138389A0 (id)
NO (1) NO20005023L (id)
PL (1) PL343313A1 (id)
SK (1) SK14982000A3 (id)
TR (1) TR200002851T2 (id)
WO (1) WO1999051228A1 (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224189B1 (en) * 1999-10-07 2006-01-25 Eli Lilly And Company Condensed dihydroquinolinone derivatives for inhibiting mrp1
US6743794B2 (en) 1999-12-22 2004-06-01 Eli Lilly And Company Methods and compounds for inhibiting MRP1
ES2233487T3 (es) * 1999-12-22 2005-06-16 Eli Lilly And Company Procedimientos y compuestos para la inhibicion de mrp1.
EP1301518A1 (en) 2000-06-14 2003-04-16 Eli Lilly And Company Tricyclic compounds as mrp1-inhibitors
JP2004509897A (ja) * 2000-09-22 2004-04-02 イーライ・リリー・アンド・カンパニー シクロヘキシルアミン誘導体の立体選択的製造方法
JP2004525952A (ja) * 2001-04-09 2004-08-26 イーライ・リリー・アンド・カンパニー Ｍｒｐ１を阻害するための化合物および医薬組成物
WO2002081482A1 (en) * 2001-04-09 2002-10-17 Eli Lilly And Company Compounds and methods for inhibiting mrp1
US7064131B2 (en) 2001-04-09 2006-06-20 Eli Lilly And Company Compounds and methods for inhibiting MRP1
WO2005048953A2 (en) * 2003-11-13 2005-06-02 Ambit Biosciences Corporation Amide derivatives as kinase modulators
CA2564429A1 (en) * 2004-05-14 2005-12-01 Irm Llc Compounds and compositions as ppar modulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588731A (en) * 1985-06-21 1986-05-13 Roussel Uclaf Derivatives of isoxazolo[4,5-c]quinoline(2H)-3-one and method of preparation and use as anxiolytic agents
US5744485A (en) 1994-03-25 1998-04-28 Vertex Pharmaceuticals Incorporated Carbamates and ureas as modifiers of multi-drug resistance
US5717092A (en) 1996-03-29 1998-02-10 Vertex Pharmaceuticals Inc. Compounds with improved multi-drug resistance activity

Also Published As

Publication number Publication date
HUP0101508A3 (en) 2002-04-29
TR200002851T2 (tr) 2000-12-21
KR20010042471A (ko) 2001-05-25
CA2327617A1 (en) 1999-10-14
NO20005023D0 (no) 2000-10-05
CN1304306A (zh) 2001-07-18
EA200001034A1 (ru) 2001-04-23
NO20005023L (no) 2000-12-05
EP1067928A1 (en) 2001-01-17
AU3476999A (en) 1999-10-25
HUP0101508A2 (hu) 2001-10-28
SK14982000A3 (sk) 2001-05-10
US6369070B1 (en) 2002-04-09
BR9910112A (pt) 2000-12-26
EP1067928A4 (en) 2001-11-14
WO1999051228A1 (en) 1999-10-14
IL138389A0 (en) 2001-10-31
HRP20000646A2 (en) 2001-06-30
PL343313A1 (en) 2001-08-13
JP2002510625A (ja) 2002-04-09

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