ID27854A - Senyawa-senyawa siklik yang berguna dalam pengobatan disilipidaemia, atherosklerosis dan diabetis, komposisi-komposisi farmasi dan proses penyiapannya - Google Patents

Senyawa-senyawa siklik yang berguna dalam pengobatan disilipidaemia, atherosklerosis dan diabetis, komposisi-komposisi farmasi dan proses penyiapannya

Info

Publication number
ID27854A
ID27854A IDW20010261A ID20010261A ID27854A ID 27854 A ID27854 A ID 27854A ID W20010261 A IDW20010261 A ID W20010261A ID 20010261 A ID20010261 A ID 20010261A ID 27854 A ID27854 A ID 27854A
Authority
ID
Indonesia
Prior art keywords
compounds
atherosclerosis
disilipidaemia
cycle
preparation processes
Prior art date
Application number
IDW20010261A
Other languages
English (en)
Inventor
Jean-Jacques Berthelon
Daniel Guerrier
Eric Raspe
Jean-Jacques Zeiller
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ID27854A publication Critical patent/ID27854A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
IDW20010261A 1998-07-17 1999-07-09 Senyawa-senyawa siklik yang berguna dalam pengobatan disilipidaemia, atherosklerosis dan diabetis, komposisi-komposisi farmasi dan proses penyiapannya ID27854A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9809164A FR2781222A1 (fr) 1998-07-17 1998-07-17 Composes cycliques utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procede de preparation

Publications (1)

Publication Number Publication Date
ID27854A true ID27854A (id) 2001-04-26

Family

ID=9528730

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010261A ID27854A (id) 1998-07-17 1999-07-09 Senyawa-senyawa siklik yang berguna dalam pengobatan disilipidaemia, atherosklerosis dan diabetis, komposisi-komposisi farmasi dan proses penyiapannya

Country Status (22)

Country Link
US (1) US6528538B1 (id)
EP (1) EP1098893B1 (id)
JP (1) JP2002520407A (id)
KR (1) KR20010070966A (id)
CN (1) CN1309655A (id)
AT (1) ATE235485T1 (id)
AU (1) AU753287B2 (id)
BR (1) BR9912138A (id)
CA (1) CA2337481A1 (id)
DE (1) DE69906303T2 (id)
DK (1) DK1098893T3 (id)
ES (1) ES2192853T3 (id)
FR (1) FR2781222A1 (id)
HK (1) HK1039615A1 (id)
HU (1) HUP0103411A3 (id)
ID (1) ID27854A (id)
NO (1) NO20010266L (id)
PL (1) PL345397A1 (id)
PT (1) PT1098893E (id)
SK (1) SK482001A3 (id)
WO (1) WO2000004011A1 (id)
ZA (1) ZA200101303B (id)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
RS20100015A (sr) 2001-01-26 2010-12-31 Schering Corporation Kombinacija aktivatora receptora aktiviranog peroksizom- proliferatorom (ppar) fenofibrata sa inhibitorom apsorpcije sterola ezetimibom za vaskularne indikacije
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
PT1355644E (pt) 2001-01-26 2006-11-30 Schering Corp Utilização de compostos azetidinona substituídos para o tratamento de sitosterolemia
TWI311133B (en) 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
EP1452521A4 (en) 2001-08-17 2007-03-14 Eisai R&D Man Co Ltd CYCLIC COMPOUND AND AGONIST OF PPAR RECEPTOR
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
EP1429756B1 (en) 2001-09-21 2006-11-22 Schering Corporation Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors
JP2006508188A (ja) 2002-11-06 2006-03-09 シェーリング コーポレイション 脱髄の処置のためのコレステロール吸収インヒビター
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CN1756756A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
CN1756755A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
DE602004016123D1 (de) 2003-03-07 2008-10-09 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
AU2004233863B2 (en) * 2003-04-24 2010-06-17 Incyte Holdings Corporation Aza spiro alkane derivatives as inhibitors of metalloproteases
CN1930152A (zh) * 2004-01-09 2007-03-14 卡地拉健康护理有限公司 用于治疗i.a.肥胖症和糖尿病的1,3-二噁烷衍生物及其类似物
WO2006018855A1 (en) * 2004-08-20 2006-02-23 Cadila Healthcare Limited Novel antidiabetic compounds
CN100389112C (zh) * 2004-12-16 2008-05-21 中国石油化工股份有限公司 一类环状缩醛和缩酮化合物及其应用
WO2007099553A2 (en) * 2006-02-27 2007-09-07 Cadila Healthcare Limited 1,3-dioxane carboxylic acids
KR20090010035A (ko) * 2006-05-18 2009-01-28 웰스태트 테러퓨틱스 코포레이션 물질대사 장애의 치료용 화합물
US7910108B2 (en) * 2006-06-05 2011-03-22 Incyte Corporation Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases
WO2016056031A1 (en) 2014-10-08 2016-04-14 Council Of Scientific & Industrial Research Novel diol compounds synthesis and its use for formal synthesis of (2r, 3 s)-3-hydroxypipecolic acid
US9637575B2 (en) * 2014-12-31 2017-05-02 W. R. Grace & Co. -Conn. Catalyst system, olefin polymerization catalyst components comprising at least an internal electron donor compound, and methods of making and using the same
CN114867702A (zh) * 2019-12-13 2022-08-05 罗地亚经营管理公司 苯衍生物的生产

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032536A (en) 1976-07-22 1977-06-28 Janssen Pharmaceutica N.V. (1h-benzimidazol-2-yl)carbamates
US5179216A (en) * 1990-08-16 1993-01-12 American Home Products Corporation N,n', n'-trisubstituted-5-bisaminomethylene-1,3-dioxane-4,6-dione inhibitors of acyl-coa:cholesterol-acyl transferase
TW209868B (id) * 1991-04-04 1993-07-21 Yoshitomi Pharmaceutical
DE19637840A1 (de) * 1996-09-17 1998-03-19 Henkel Kgaa Verwendung von geminalen Dialkoxyalkansäureestern zur Herstellung von desodorierenden Körperpflegemitteln

Also Published As

Publication number Publication date
KR20010070966A (ko) 2001-07-28
EP1098893B1 (en) 2003-03-26
ES2192853T3 (es) 2003-10-16
SK482001A3 (en) 2001-09-11
US6528538B1 (en) 2003-03-04
HK1039615A1 (zh) 2002-05-03
CA2337481A1 (en) 2000-01-27
ZA200101303B (en) 2002-05-15
FR2781222A1 (fr) 2000-01-21
DE69906303D1 (de) 2003-04-30
NO20010266D0 (no) 2001-01-16
AU5034799A (en) 2000-02-07
BR9912138A (pt) 2001-04-10
PL345397A1 (en) 2001-12-17
DK1098893T3 (da) 2003-07-07
HUP0103411A3 (en) 2002-08-28
AU753287B2 (en) 2002-10-17
DE69906303T2 (de) 2003-12-11
JP2002520407A (ja) 2002-07-09
ATE235485T1 (de) 2003-04-15
HUP0103411A2 (hu) 2002-04-29
NO20010266L (no) 2001-01-16
CN1309655A (zh) 2001-08-22
EP1098893A1 (en) 2001-05-16
WO2000004011A1 (en) 2000-01-27
PT1098893E (pt) 2003-08-29

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