ID28494A - INHIBITOR FAKTOR VIIa - Google Patents

INHIBITOR FAKTOR VIIa

Info

Publication number
ID28494A
ID28494A IDW20010598A ID20010598A ID28494A ID 28494 A ID28494 A ID 28494A ID W20010598 A IDW20010598 A ID W20010598A ID 20010598 A ID20010598 A ID 20010598A ID 28494 A ID28494 A ID 28494A
Authority
ID
Indonesia
Prior art keywords
factor viia
inhibitor factor
inhibitor
viia
factor
Prior art date
Application number
IDW20010598A
Other languages
English (en)
Indonesian (id)
Inventor
Safar Pavel
Safarova Alena
Wildgoose Peter
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID28494A publication Critical patent/ID28494A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDW20010598A 1998-09-15 1999-09-02 INHIBITOR FAKTOR VIIa ID28494A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98117506A EP0987274A1 (de) 1998-09-15 1998-09-15 Faktor VIIa Inhibitore

Publications (1)

Publication Number Publication Date
ID28494A true ID28494A (id) 2001-05-31

Family

ID=8232644

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010598A ID28494A (id) 1998-09-15 1999-09-02 INHIBITOR FAKTOR VIIa

Country Status (25)

Country Link
US (1) US6287794B1 (de)
EP (2) EP0987274A1 (de)
JP (1) JP4537581B2 (de)
KR (1) KR100665490B1 (de)
CN (1) CN1203087C (de)
AR (1) AR027814A1 (de)
AT (1) ATE460424T1 (de)
AU (1) AU760580B2 (de)
BR (1) BR9913742A (de)
CA (1) CA2344048A1 (de)
CZ (1) CZ300249B6 (de)
DE (1) DE69942123D1 (de)
HK (1) HK1040253B (de)
HU (1) HUP0103851A3 (de)
ID (1) ID28494A (de)
IL (2) IL141415A0 (de)
MY (1) MY125150A (de)
NO (1) NO328523B1 (de)
NZ (1) NZ510509A (de)
PL (1) PL203227B1 (de)
RU (1) RU2223967C2 (de)
TR (1) TR200100766T2 (de)
TW (1) TW576839B (de)
WO (1) WO2000015658A1 (de)
ZA (1) ZA200101861B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0987274A1 (de) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Faktor VIIa Inhibitore
US6472393B1 (en) 1999-01-13 2002-10-29 Genentech, Inc. Serine protease inhibitors
EP1059302A1 (de) * 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Faktor VIIa Inhibitore
HUP0203486A2 (hu) * 1999-10-01 2003-02-28 Chugai Seiyaku Kabushiki Kaisha Véralvadással összefüggő betegségek megelőzése és kezelése
EP1095933A1 (de) 1999-10-30 2001-05-02 Aventis Pharma Deutschland GmbH N-Guanidinoalkylamide, Verfahren zu ihrer Herstellung, ihre Verwendung und pharmazeutische Zusammensetzungen, die sie enthalten
EP1162194A1 (de) * 2000-06-06 2001-12-12 Aventis Pharma Deutschland GmbH Auf Faktor VIIa inhibitorisch wirkende (Thio)-Harnstoff Verbindungen, Verfahren zu deren Herstellung und deren Verwendung
GB0014134D0 (en) * 2000-06-10 2000-08-02 Astrazeneca Ab Combination therapy
NZ526003A (en) 2000-10-20 2005-09-30 Biocryst Pharm Inc Biaryl compounds as serine protease inhibitors
AU3320602A (en) 2000-12-06 2002-06-18 Aventis Pharma Gmbh Guanidine and amidine derivatives as factor xa inhibitors
EP1364960A4 (de) * 2001-02-02 2005-05-18 Chugai Pharmaceutical Co Ltd Peptidderivate
EP1270551A1 (de) * 2001-06-26 2003-01-02 Aventis Pharma Deutschland GmbH Harnstoffverbindungen mit antiproteolytischer Wirkung
EP1314733A1 (de) 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indol-2-carbonsäureamide als Faktor-Xa-Hemmer
AU2003290663A1 (en) * 2002-11-13 2004-06-03 Haematologic Technologies, Inc. Assay for tissue factor and factor viia
US7358268B2 (en) 2002-12-04 2008-04-15 Sanofi-Aventis Deutschland Gmbh Imidazole derivatives as factor Xa inhibitors
US7429581B2 (en) 2002-12-23 2008-09-30 Sanofi-Aventis Deutschland Gmbh Pyrazole-derivatives as factor Xa inhibitors
EP1479675A1 (de) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Indazolderivate als Faktor Xa-Inhibitoren
EP1479680A1 (de) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Azaindole-Derivative als Faktor Xa Hemmer
EP1479677A1 (de) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Neue Indolderivate als Faktor Xa-Inhibitoren
US7317027B2 (en) 2003-05-19 2008-01-08 Sanofi-Aventis Deutschland Gmbh Azaindole-derivatives as factor Xa inhibitors
US7741341B2 (en) 2003-05-19 2010-06-22 Sanofi-Aventis Deutschland Gmbh Benzimidazole-derivatives as factor Xa inhibitors
US7223780B2 (en) 2003-05-19 2007-05-29 Sanofi-Aventis Deutschland Gmbh Triazole-derivatives as blood clotting enzyme factor Xa inhibitors
CA2525713A1 (en) 2003-05-20 2004-12-29 Genentech, Inc. Benzofuran inhibitors of factor viia
AU2004249670A1 (en) 2003-05-20 2004-12-29 Genentech, Inc. Acylsulfamide inhibitors of factor VIIa
EP1568698A1 (de) 2004-02-27 2005-08-31 Aventis Pharma Deutschland GmbH Pyrrolderivate als faktor-xa-inhibitoren
CN1984664B (zh) * 2004-05-27 2013-07-24 巴克斯特国际公司 应用硫酸多糖治疗出血障碍的方法
WO2008107362A2 (en) * 2007-03-07 2008-09-12 Novo Nordisk Health Care Ag Stabiliser and inhibitors of factor vii
JP2010532769A (ja) 2007-07-10 2010-10-14 サノフィ−アベンティス 抗血栓作用を有するマロンアミド誘導体
CN101981050A (zh) * 2008-01-23 2011-02-23 诺沃-诺迪斯克保健股份有限公司 新的凝血因子抑制剂
US9901597B2 (en) 2011-02-04 2018-02-27 Octapharma Ag Method for inactivation/removal of coagulation factors by precipitation
KR20210062649A (ko) * 2018-09-11 2021-05-31 앤비션 에스.알.엘. 펩티드 및 이의 의학적 용도
AU2019340465B2 (en) * 2018-09-11 2025-08-14 Anbition S.R.L. Peptides and medical uses thereof
JP7775080B2 (ja) 2019-07-01 2025-11-25 トニックス ファーマ リミテッド 抗ｃｄ１５４抗体およびその使用
US20240059781A1 (en) 2021-01-06 2024-02-22 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies
GB202209228D0 (en) * 2022-06-23 2022-08-10 Univ Strathclyde Modified amino acids and uses thereof
WO2025248134A1 (en) 2024-05-31 2025-12-04 Tonix Pharma Limited Treatment methods comprising administration of modified cd154 antibodies

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
AU4338689A (en) * 1988-09-23 1990-04-18 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
CA2008116C (en) * 1989-02-23 2001-11-20 Thomas Weller Glycine derivatives
US5190919A (en) * 1989-11-13 1993-03-02 Board Of Regents, The University Of Texas System Antihemostatic factor vii peptides
HU206372B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same
US5506134A (en) 1990-10-22 1996-04-09 Corvas International, Inc. Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
US5788965A (en) 1991-02-28 1998-08-04 Novo Nordisk A/S Modified factor VII
US5833982A (en) 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
CN1125450A (zh) * 1993-06-18 1996-06-26 哈夫思伦·尼卡姆德公司 因子vii衍生的肽
US5849510A (en) * 1994-04-26 1998-12-15 Selectide Corporation Factor Xa inhibitors
AU707653B2 (en) * 1994-04-26 1999-07-15 Selectide Corporation Factor Xa inhibitors
RU2097033C1 (ru) * 1994-09-30 1997-11-27 Московская государственная академия тонкой химической технологии им.М.В.Ломоносова Имидазолсодержащие ингибиторы катепсин g-индуцированной агрегации тромбоцитов
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
EP0892780B1 (de) * 1996-02-22 2002-11-20 Bristol-Myers Squibb Pharma Company M-amidinophenyl-analoga als faktor-xa-inhibitoren
EP0987274A1 (de) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Faktor VIIa Inhibitore

Also Published As

Publication number Publication date
AU5972399A (en) 2000-04-03
JP2002524571A (ja) 2002-08-06
WO2000015658A1 (en) 2000-03-23
HUP0103851A3 (en) 2002-05-28
HK1040253A1 (en) 2002-05-31
DE69942123D1 (de) 2010-04-22
HK1040253B (zh) 2005-09-02
NO20011293L (no) 2001-05-04
CZ300249B6 (cs) 2009-04-01
BR9913742A (pt) 2001-06-05
ATE460424T1 (de) 2010-03-15
IL141415A0 (en) 2002-03-10
PL203227B1 (pl) 2009-09-30
MY125150A (en) 2006-07-31
TW576839B (en) 2004-02-21
CA2344048A1 (en) 2000-03-23
JP4537581B2 (ja) 2010-09-01
NZ510509A (en) 2002-09-27
ZA200101861B (en) 2001-10-22
EP0987274A1 (de) 2000-03-22
IL141415A (en) 2006-09-05
CN1318069A (zh) 2001-10-17
US6287794B1 (en) 2001-09-11
PL346781A1 (en) 2002-02-25
KR20010075130A (ko) 2001-08-09
EP1114061B1 (de) 2010-03-10
KR100665490B1 (ko) 2007-01-10
RU2223967C2 (ru) 2004-02-20
NO20011293D0 (no) 2001-03-14
EP1114061A1 (de) 2001-07-11
CZ2001914A3 (en) 2001-06-13
NO328523B1 (no) 2010-03-08
AR027814A1 (es) 2003-04-16
AU760580B2 (en) 2003-05-15
TR200100766T2 (tr) 2001-10-22
CN1203087C (zh) 2005-05-25
HUP0103851A2 (hu) 2002-04-29

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