IE32443B1 - Pharmaceutical compositions containing 2-aryl thiazoles - Google Patents

Pharmaceutical compositions containing 2-aryl thiazoles

Info

Publication number
IE32443B1
IE32443B1 IE121768A IE121768A IE32443B1 IE 32443 B1 IE32443 B1 IE 32443B1 IE 121768 A IE121768 A IE 121768A IE 121768 A IE121768 A IE 121768A IE 32443 B1 IE32443 B1 IE 32443B1
Authority
IE
Ireland
Prior art keywords
radical
pharmaceutical compositions
compositions containing
cooh
amide
Prior art date
Application number
IE121768A
Other versions
IE32443L (en
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of IE32443L publication Critical patent/IE32443L/en
Publication of IE32443B1 publication Critical patent/IE32443B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Novel thiazoles which have an antiinflammatory effect and which can be used as pharmaceuticals and correspond to the formula (I) <IMAGE> in which R1 is an optionally substituted carbocyclic or heterocyclic aromatic radical; R2 is a radical of the formula -CH=CH-COOH or -CH2-CH2-COOH or the radical of a salt or amide of these acids; and R3 is hydrogen or an alkyl radical with 1 to 4 carbon atoms, and their acid addition salts, with the proviso that R2 is the radical of a salt or amide of the said acid groups if R1 is an unsubstituted phenyl radical or a mono- or dimethoxyphenyl radical and R3 is a hydrogen atom, are obtained by hydrolysing the corresponding cyanoethenyl or cyanoethyl derivatives. [GB1237194A]
IE121768A 1967-10-26 1968-10-11 Pharmaceutical compositions containing 2-aryl thiazoles IE32443B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB48640/67A GB1237194A (en) 1967-10-26 1967-10-26 Pharmaceutical compositions containing 2-arylthiazoles

Publications (2)

Publication Number Publication Date
IE32443L IE32443L (en) 1969-04-26
IE32443B1 true IE32443B1 (en) 1973-08-08

Family

ID=10449369

Family Applications (1)

Application Number Title Priority Date Filing Date
IE121768A IE32443B1 (en) 1967-10-26 1968-10-11 Pharmaceutical compositions containing 2-aryl thiazoles

Country Status (9)

Country Link
JP (1) JPS4810466B1 (en)
BE (1) BE722290A (en)
CA (1) CA930740A (en)
CH (2) CH540280A (en)
DE (1) DE1804448C3 (en)
FR (2) FR7971M (en)
GB (1) GB1237194A (en)
IE (1) IE32443B1 (en)
NL (1) NL165932C (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8725475D0 (en) * 1987-10-30 1987-12-02 Amp Holland Modular jack
KR100736955B1 (en) * 2002-08-30 2007-07-09 에프. 호프만-라 로슈 아게 Novel 2-arylthiazole compounds as pparalpha and ppargamma agonists
EP1939180A1 (en) 2006-12-20 2008-07-02 sanofi-aventis Heteroarylacrylamides and their use as pharmaceuticals for the stimulation of the expression of endothelial NO synthase
EP1939181A1 (en) * 2006-12-27 2008-07-02 sanofi-aventis Heteroaryl-substituted carboxamides and use thereof for the stimulation of the expression of NO synthase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130759C (en) * 1965-10-07

Also Published As

Publication number Publication date
CH609051A5 (en) 1979-02-15
FR1587945A (en) 1970-04-03
NL165932B (en) 1981-01-15
NL6815215A (en) 1969-04-29
DE1804448A1 (en) 1969-08-14
NL165932C (en) 1981-06-15
CA930740A (en) 1973-07-24
FR7971M (en) 1970-06-01
CH540280A (en) 1973-08-15
IE32443L (en) 1969-04-26
BE722290A (en) 1969-04-14
JPS4810466B1 (en) 1973-04-03
GB1237194A (en) 1971-06-30
DE1804448B2 (en) 1980-07-03
DE1804448C3 (en) 1981-04-02

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