IE32961L - 2-alkoxy-3, 5-dihalobenzene alkylaminoalkyl ethers - Google Patents
2-alkoxy-3, 5-dihalobenzene alkylaminoalkyl ethersInfo
- Publication number
- IE32961L IE32961L IE690173A IE17369A IE32961L IE 32961 L IE32961 L IE 32961L IE 690173 A IE690173 A IE 690173A IE 17369 A IE17369 A IE 17369A IE 32961 L IE32961 L IE 32961L
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- alkoxy
- acid
- acetylating
- monoether
- Prior art date
Links
- -1 alkylaminoalkyl ethers Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001348 alkyl chlorides Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940066768 systemic antihistamines aminoalkyl ethers Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Insulating Bodies (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,251,695. Aminoalkyl ethers of 2-(alkoxy) - 3,5-dihalobenzenes. SOC. D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE. 13 Feb., 1969 [16 Feb., 1968; 10 May, 1968], No. 7933/69. HeadingC2C. Novel compounds of the Formula (I) and their acid-addition salts with a mineral or organic acid and their quaternary ammonium salts, wherein n and m each is 0, 1 or 2, R, R l and R 2 each is H or C 1-5 alkyl, R 3 is C 1-5 alkyl, or the group NR 1 R 2 represents a heterocyclic radical, and X and Y are halogens, are obtained by acetylating a monoether of pyrocatechol, then halogenating the product, de-acetylating the halogenated product and treating the dihalo-pyrocatechol monoether with an appropriate (substituted amino) alkyl chloride, and optionally forming acid or quaternary ammonium salts. Pharmaceutical compositions, useful as spasmogenie agents, contain compounds of Formula (I) above as active ingredients, and may be formulated as tablets or solutions.
[GB1251695A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR140294 | 1968-02-16 | ||
| FR151632A FR7615M (en) | 1968-05-10 | 1968-05-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32961L true IE32961L (en) | 1969-08-16 |
| IE32961B1 IE32961B1 (en) | 1974-02-06 |
Family
ID=26181810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE173/69A IE32961B1 (en) | 1968-02-16 | 1969-02-11 | New dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzene and process for the preparation thereof |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS4934669B1 (en) |
| BE (1) | BE728221A (en) |
| BG (1) | BG15205A3 (en) |
| BR (1) | BR6906462D0 (en) |
| CA (1) | CA928299A (en) |
| CH (1) | CH490328A (en) |
| CS (1) | CS155198B2 (en) |
| DK (1) | DK125020B (en) |
| ES (1) | ES363662A1 (en) |
| FI (1) | FI50789C (en) |
| GB (1) | GB1251695A (en) |
| IE (1) | IE32961B1 (en) |
| IL (1) | IL31594A (en) |
| LU (1) | LU58009A1 (en) |
| MC (1) | MC809A1 (en) |
| NL (1) | NL138921B (en) |
| NO (1) | NO128958B (en) |
| OA (1) | OA03885A (en) |
| SE (1) | SE367184B (en) |
| YU (1) | YU33793B (en) |
| ZM (1) | ZM969A1 (en) |
-
1969
- 1969-02-10 OA OA53502A patent/OA03885A/en unknown
- 1969-02-10 FI FI690407A patent/FI50789C/en active
- 1969-02-11 ZM ZM9/69A patent/ZM969A1/en unknown
- 1969-02-11 IL IL31594A patent/IL31594A/en unknown
- 1969-02-11 BE BE728221D patent/BE728221A/xx not_active IP Right Cessation
- 1969-02-11 IE IE173/69A patent/IE32961B1/en unknown
- 1969-02-13 MC MC808A patent/MC809A1/en unknown
- 1969-02-13 GB GB1251695D patent/GB1251695A/en not_active Expired
- 1969-02-13 YU YU332/69A patent/YU33793B/en unknown
- 1969-02-13 CH CH219269A patent/CH490328A/en not_active IP Right Cessation
- 1969-02-14 DK DK82569AA patent/DK125020B/en not_active IP Right Cessation
- 1969-02-14 JP JP44011462A patent/JPS4934669B1/ja active Pending
- 1969-02-14 NL NL696902401A patent/NL138921B/en not_active IP Right Cessation
- 1969-02-14 CA CA043022A patent/CA928299A/en not_active Expired
- 1969-02-14 LU LU58009D patent/LU58009A1/xx unknown
- 1969-02-14 ES ES363662A patent/ES363662A1/en not_active Expired
- 1969-02-14 BR BR206462/69A patent/BR6906462D0/en unknown
- 1969-02-14 SE SE02048/69A patent/SE367184B/xx unknown
- 1969-02-14 NO NO00599/69A patent/NO128958B/no unknown
- 1969-02-17 CS CS106069A patent/CS155198B2/cs unknown
- 1969-11-10 BG BG011634A patent/BG15205A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1906551B2 (en) | 1975-07-17 |
| NL138921B (en) | 1973-05-15 |
| NL6902401A (en) | 1969-08-19 |
| OA03885A (en) | 1975-08-14 |
| FI50789C (en) | 1976-07-12 |
| BG15205A3 (en) | 1972-05-20 |
| LU58009A1 (en) | 1969-09-18 |
| JPS4934669B1 (en) | 1974-09-17 |
| IL31594A0 (en) | 1969-04-30 |
| SE367184B (en) | 1974-05-20 |
| YU33793B (en) | 1978-05-15 |
| ZM969A1 (en) | 1969-11-17 |
| IL31594A (en) | 1973-02-28 |
| BR6906462D0 (en) | 1973-01-16 |
| ES363662A1 (en) | 1971-01-01 |
| DE1906551A1 (en) | 1969-08-21 |
| YU33269A (en) | 1977-10-31 |
| CA928299A (en) | 1973-06-12 |
| MC809A1 (en) | 1970-07-30 |
| CS155198B2 (en) | 1974-05-30 |
| DK125020B (en) | 1972-12-18 |
| CH490328A (en) | 1970-05-15 |
| FI50789B (en) | 1976-03-31 |
| GB1251695A (en) | 1971-10-27 |
| IE32961B1 (en) | 1974-02-06 |
| NO128958B (en) | 1974-02-04 |
| BE728221A (en) | 1969-08-11 |
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