IE33318L - Bile acid binding process - Google Patents
Bile acid binding processInfo
- Publication number
- IE33318L IE33318L IE691293A IE129369A IE33318L IE 33318 L IE33318 L IE 33318L IE 691293 A IE691293 A IE 691293A IE 129369 A IE129369 A IE 129369A IE 33318 L IE33318 L IE 33318L
- Authority
- IE
- Ireland
- Prior art keywords
- acid
- bile
- taurine
- resin
- acid binding
- Prior art date
Links
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 title abstract 3
- 239000003613 bile acid Substances 0.000 title abstract 3
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 abstract 7
- 229920005989 resin Polymers 0.000 abstract 3
- 239000011347 resin Substances 0.000 abstract 3
- 229960003080 taurine Drugs 0.000 abstract 3
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 abstract 2
- 102000030904 bile acid binding Human genes 0.000 abstract 2
- 108091022863 bile acid binding Proteins 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 229920002873 Polyethylenimine Polymers 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000006229 amino acid addition Effects 0.000 abstract 1
- 239000003957 anion exchange resin Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- VVIUBCNYACGLLV-UHFFFAOYSA-N hypotaurine Chemical compound [NH3+]CCS([O-])=O VVIUBCNYACGLLV-UHFFFAOYSA-N 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229920005990 polystyrene resin Polymers 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,262,556. Bile-acid binding compositions. BRISTOL-MYERS CO. 19 Sept., 1969 [20 Sept., 1968], No. 46240/69. Heading A5B. A composition for binding bile-acid in the digestive tract of a taurine/bile acid conjugatesecreting animal (or human) comprises a non- toxic, bile-acid binding anion exchange resin and taurine or a salt or a precursor thereof (e.g. cysteine, cysteine-sulphinic acid, hypotaurine and methionine). The preferred resin is cholesstyramine; others mentioned include polystyrene resins cross-linked with divinyl benzene and containing amino acid addition salt or quaternary ammonium exchange groups, certain cellulose and dextran derivatives and polyethylene imine resins. The invention also comprises the treatment of non-human animals for the above-mentioned purpose by concamitantly administering thereto the resin and taurine or taurine derivative.
[GB1262556A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76111568A | 1968-09-20 | 1968-09-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33318L true IE33318L (en) | 1970-03-20 |
| IE33318B1 IE33318B1 (en) | 1974-05-15 |
Family
ID=25061185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1293/69A IE33318B1 (en) | 1968-09-20 | 1969-09-15 | Intestinal bile acid binding process and compositions |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT296497B (en) |
| BE (1) | BE739142A (en) |
| BR (1) | BR6912543D0 (en) |
| DE (1) | DE1947670A1 (en) |
| FR (1) | FR2018540B1 (en) |
| GB (1) | GB1262556A (en) |
| IE (1) | IE33318B1 (en) |
| IL (1) | IL33008A (en) |
| PH (1) | PH9499A (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797288A (en) * | 1984-10-05 | 1989-01-10 | Warner-Lambert Company | Novel drug delivery system |
| US4804548A (en) * | 1984-10-05 | 1989-02-14 | Warner-Lambert Company | Novel sweetener delivery systems |
| US4828857A (en) * | 1984-10-05 | 1989-05-09 | Warner-Lambert Company | Novel sweetener delivery systems |
| US4818539A (en) * | 1985-02-05 | 1989-04-04 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4790991A (en) * | 1985-02-05 | 1988-12-13 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4843098A (en) * | 1985-02-05 | 1989-06-27 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4747881A (en) * | 1985-02-05 | 1988-05-31 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4851392A (en) * | 1985-02-05 | 1989-07-25 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| GB8517299D0 (en) * | 1985-07-09 | 1985-08-14 | Salim A S M | Dermatologically active substances |
| US5167965A (en) * | 1987-02-09 | 1992-12-01 | The Dow Chemical Company | Palatable cholestyramine granules, tablets and methods for preparation thereof |
-
1969
- 1969-09-15 IE IE1293/69A patent/IE33318B1/en unknown
- 1969-09-17 IL IL33008A patent/IL33008A/en unknown
- 1969-09-18 BR BR212543/69A patent/BR6912543D0/en unknown
- 1969-09-18 PH PH10734*UA patent/PH9499A/en unknown
- 1969-09-19 AT AT892869A patent/AT296497B/en not_active IP Right Cessation
- 1969-09-19 GB GB46240/69A patent/GB1262556A/en not_active Expired
- 1969-09-19 BE BE739142D patent/BE739142A/xx unknown
- 1969-09-19 FR FR696931975A patent/FR2018540B1/fr not_active Expired
- 1969-09-19 DE DE19691947670 patent/DE1947670A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PH9499A (en) | 1976-01-09 |
| BE739142A (en) | 1970-03-02 |
| AT296497B (en) | 1972-02-10 |
| FR2018540A1 (en) | 1970-05-29 |
| DE1947670A1 (en) | 1970-04-02 |
| IL33008A0 (en) | 1969-11-30 |
| IL33008A (en) | 1973-02-28 |
| BR6912543D0 (en) | 1973-05-10 |
| IE33318B1 (en) | 1974-05-15 |
| GB1262556A (en) | 1972-02-02 |
| FR2018540B1 (en) | 1973-01-12 |
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