IE34433B1 - Modified allergens and a process for their preparation - Google Patents

Modified allergens and a process for their preparation

Info

Publication number
IE34433B1
IE34433B1 IE100170A IE100170A IE34433B1 IE 34433 B1 IE34433 B1 IE 34433B1 IE 100170 A IE100170 A IE 100170A IE 100170 A IE100170 A IE 100170A IE 34433 B1 IE34433 B1 IE 34433B1
Authority
IE
Ireland
Prior art keywords
pref
preparation
carbodiimide
allergy
modified allergens
Prior art date
Application number
IE100170A
Other versions
IE34433L (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB23853/70A external-priority patent/GB1282163A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IE34433L publication Critical patent/IE34433L/en
Publication of IE34433B1 publication Critical patent/IE34433B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)

Abstract

The allergy producing properties of the material are lowered by inter and/or intra molecular action. Pref. the material is reacted with a polyaldehyde, polyketone, carbodiimide, epihalohydrin, or inorganic cyanate in acid medium, to give a modified material insoluble or barely soluble in water. Cpds. esp. used are glutaraldehyde, phenylglyoxal, 2-nitroindane-1,3-dione at pH 4-8 or, 1-cyclohexyl-3-(2-morpholino-ethyl)-carbodiimide metho-p-toluenesulphonate, or KCN at pH is approx. 5. Pref. the allergy inducing material is pollen(s). [DE2039223A1]
IE100170A 1969-08-06 1970-08-04 Modified allergens and a process for their preparation IE34433B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB3928969 1969-08-06
GB23853/70A GB1282163A (en) 1969-08-06 1969-08-06 Modified allergens and a process for their preparation
GB2362170 1970-05-15

Publications (2)

Publication Number Publication Date
IE34433L IE34433L (en) 1971-02-06
IE34433B1 true IE34433B1 (en) 1975-05-14

Family

ID=27258241

Family Applications (1)

Application Number Title Priority Date Filing Date
IE100170A IE34433B1 (en) 1969-08-06 1970-08-04 Modified allergens and a process for their preparation

Country Status (12)

Country Link
JP (1) JPS4935413B1 (en)
AT (1) AT297930B (en)
BE (1) BE754523A (en)
CA (1) CA950358A (en)
CH (2) CH569743A5 (en)
DE (1) DE2039223C3 (en)
DK (1) DK127954B (en)
ES (1) ES382486A1 (en)
IE (1) IE34433B1 (en)
NL (1) NL168419C (en)
NO (1) NO135015C (en)
SE (1) SE396694B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1492973A (en) * 1974-02-16 1977-11-23 Beecham Group Ltd Process for preparing injectable compositions
US4234569A (en) * 1978-10-04 1980-11-18 The Johns Hopkins University Production of aldehyde-treated allergen-containing substances
DE19543592C1 (en) * 1995-11-23 1997-02-20 Gsf Forschungszentrum Umwelt Pollen test medium contains pollen slurry in soln. of L-sugars contg. boron cpds.
DK0876140T3 (en) * 1996-01-25 2003-12-15 Schering Ag Improved contrast agent solutions for intravasal use
IT1391559B1 (en) * 2008-09-01 2012-01-11 Lofarma Spa ALLERGOIDS DERIVED FROM ALLERGENS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098693A (en) * 1960-05-27 1963-07-23 Little Inc A Treatment of protein and peptide materials to form amide linkages

Also Published As

Publication number Publication date
SE396694B (en) 1977-10-03
BE754523A (en) 1971-02-08
NO135015C (en) 1977-01-26
NL168419B (en) 1981-11-16
NL168419C (en) 1982-04-16
DE2039223C3 (en) 1981-04-30
CH570418A5 (en) 1975-12-15
AT297930B (en) 1972-04-10
ES382486A1 (en) 1974-06-16
CA950358A (en) 1974-07-02
DK127954B (en) 1974-02-11
IE34433L (en) 1971-02-06
JPS4935413B1 (en) 1974-09-21
NL7011548A (en) 1971-02-09
DE2039223B2 (en) 1980-08-07
DE2039223A1 (en) 1971-02-18
CH569743A5 (en) 1975-11-28
NO135015B (en) 1976-10-18

Similar Documents

Publication Publication Date Title
FR2068465A1 (en) Desensitized allergy inducing material
ES420488A1 (en) Process of making porous polyester granules
KR860001007A (en) Method for preparing silica and silica colloid
GB1218277A (en) Dry water-dispersible aluminium hydroxide gels
IE34433B1 (en) Modified allergens and a process for their preparation
IE37861L (en) Enzyme preparation
GB1348002A (en) Production of platelet silica gel
Askne et al. Determination of strong acid in precipitation, lake-water and air-borne matter
ES376742A1 (en) Process for the production of nitric acid with a concentration of over 70 percent by weight
ES378692A1 (en) A METHOD TO INCREASE THE STABILITY OF AN ENZYME.
ES341964A1 (en) Alkaline conversion of green tea
US3810819A (en) Anti-tumor substance from hemolytic streptococci and process for producing the same using ammonium sulfate
GB1380135A (en) Cold water soluble tea
FI853095A0 (en) FOERFARANDE FOER AOTERVINNING AV EN GELBILDANDE POLYSACKARID, AOTERVUNNEN POLYSACKARID OCH GEL BILDAD DAERMED.
GB1432713A (en) Porous inorganic support materials
ES448571A1 (en) Stable clumping factor for the identification of fibrinogen and fibrin cleavage products and process for preparing it
GB1301468A (en)
FR2060402A1 (en) Molecular sieve with silica binder
FI50125C (en) Process for the preparation of therapeutically useful / 1,1-dithenyl-1-hydroxy-propyl- (3) [/] -phenyl-alkyl] -amines and their salts.
Damle et al. Studies on glycolytic enzymes in relation to cancer. 3. Clinical significance of serum phosphohexose isomerase and aldolase in cancer of the prostate. A comparative study with serum acid phosphatase and serum alkaline phosphatase
GB1218278A (en) Stabilised aluminium hydroxide suspensions
GB1452648A (en) Cholera toxoid
FR2187312A1 (en) Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan
ES377424A1 (en) Process for grouting employing an ironhydroxide polyol setting agent
GB1349498A (en) Water-insoluble bound enzyme