IE34465L - Thiazole substituted urea derivatives - Google Patents
Thiazole substituted urea derivativesInfo
- Publication number
- IE34465L IE34465L IE701057A IE105770A IE34465L IE 34465 L IE34465 L IE 34465L IE 701057 A IE701057 A IE 701057A IE 105770 A IE105770 A IE 105770A IE 34465 L IE34465 L IE 34465L
- Authority
- IE
- Ireland
- Prior art keywords
- urea derivatives
- substituted urea
- thiazole substituted
- chcl3
- herbicidal
- Prior art date
Links
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical group C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 title 1
- 150000003672 ureas Chemical class 0.000 title 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 4
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 230000002363 herbicidal effect Effects 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- OCBFFGCSTGGPSQ-UHFFFAOYSA-N [CH2]CC Chemical compound [CH2]CC OCBFFGCSTGGPSQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- -1 thiazolyl ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Herbicidal thiazolyl ureas Cpds. of formula (I) (where X id Cl, Br, or I; R4 is CH3 or C2H5; R5 is H or CH3; R6 is CH3 or when R4 and R5 are both CH3; R6 can be C2H5 or n-C3H7) and their acid addn. salts are useful as pre- and post-emergence hercibides when applied at a rate of pref. 0.5-20 kg/ha. Herbicidal effects persist during a period of from several weeks to several months. In an example (I; X=Br, R4=R6=CH3, R5=H) was prepd. by addition of bromine in CHCl3 to a soln. of (I; R4=R6=CH3; R5=X=H) in CHCl3 with ice-cooling.
[FR2063138A1]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4086869 | 1969-08-15 | ||
| GB348870 | 1970-01-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34465L true IE34465L (en) | 1971-02-15 |
| IE34465B1 IE34465B1 (en) | 1975-05-14 |
Family
ID=26238346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1057/70A IE34465B1 (en) | 1969-08-15 | 1970-08-13 | Thiazole derivatives |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE754783A (en) |
| CA (1) | CA932335A (en) |
| CH (1) | CH525611A (en) |
| DD (1) | DD102055A5 (en) |
| DE (1) | DE2040580A1 (en) |
| FR (1) | FR2063138A1 (en) |
| IE (1) | IE34465B1 (en) |
| IL (1) | IL35109A0 (en) |
| NL (1) | NL7011738A (en) |
| OA (1) | OA03551A (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59112978A (en) * | 1982-12-21 | 1984-06-29 | Shionogi & Co Ltd | Propynylaminothiazole derivative |
| GB9823873D0 (en) * | 1998-10-30 | 1998-12-30 | Pharmacia & Upjohn Spa | 2-ureido-thiazole derivatives,process for their preparation,and their use as antitumour agents |
| AU2003243921B2 (en) | 2002-06-27 | 2009-05-07 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
| BRPI0506662B8 (en) | 2004-01-06 | 2021-05-25 | Novo Nordisk As | glucokinase activating compounds |
| EP1904438B1 (en) | 2005-07-08 | 2012-02-29 | Novo Nordisk A/S | Dicycloalkylcarbamoyl ureas as glucokinase activators |
| EP1904467B1 (en) | 2005-07-14 | 2013-05-01 | Novo Nordisk A/S | Urea glucokinase activators |
| EP2118083A1 (en) | 2007-01-09 | 2009-11-18 | Novo Nordisk A/S | Urea glucokinase activators |
| JP5226008B2 (en) | 2007-01-11 | 2013-07-03 | ノボ・ノルデイスク・エー／エス | Urea glucokinase activator |
| CN112040945A (en) | 2018-06-12 | 2020-12-04 | Vtv治疗有限责任公司 | Therapeutic use of a glucokinase activator in combination with insulin or insulin analogs |
| US12391658B2 (en) | 2020-02-18 | 2025-08-19 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
-
0
- BE BE754783D patent/BE754783A/en unknown
-
1970
- 1970-08-07 NL NL7011738A patent/NL7011738A/xx unknown
- 1970-08-11 OA OA54007A patent/OA03551A/en unknown
- 1970-08-13 IL IL35109A patent/IL35109A0/en unknown
- 1970-08-13 IE IE1057/70A patent/IE34465B1/en unknown
- 1970-08-13 CA CA090755A patent/CA932335A/en not_active Expired
- 1970-08-14 DE DE19702040580 patent/DE2040580A1/en active Pending
- 1970-08-14 CH CH1221370A patent/CH525611A/en unknown
- 1970-08-14 FR FR7030078A patent/FR2063138A1/en active Granted
- 1970-08-17 DD DD149542A patent/DD102055A5/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD102055A5 (en) | 1973-12-05 |
| FR2063138B1 (en) | 1973-01-12 |
| CH525611A (en) | 1972-07-31 |
| NL7011738A (en) | 1971-02-17 |
| BE754783A (en) | 1971-02-12 |
| OA03551A (en) | 1971-03-30 |
| FR2063138A1 (en) | 1971-07-09 |
| IE34465B1 (en) | 1975-05-14 |
| DE2040580A1 (en) | 1971-04-22 |
| IL35109A0 (en) | 1970-10-30 |
| CA932335A (en) | 1973-08-21 |
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