IE38498L - Substituted benzamides - Google Patents
Substituted benzamidesInfo
- Publication number
- IE38498L IE38498L IE200473A IE200473A IE38498L IE 38498 L IE38498 L IE 38498L IE 200473 A IE200473 A IE 200473A IE 200473 A IE200473 A IE 200473A IE 38498 L IE38498 L IE 38498L
- Authority
- IE
- Ireland
- Prior art keywords
- prepared
- compounds
- compound
- benzylamino
- benzylidene
- Prior art date
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title abstract 2
- 150000003936 benzamides Chemical class 0.000 title 1
- -1 benzylamino tritylamino Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- AQOCQFLDHPSJLR-UHFFFAOYSA-N 4-amino-n-[2-(diethylamino)ethyl]-2-methoxybenzamide Chemical compound CCN(CC)CCNC(=O)C1=CC=C(N)C=C1OC AQOCQFLDHPSJLR-UHFFFAOYSA-N 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000000440 benzylamino group Chemical group [H]N(*)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- UDGSVBYJWHOHNN-UHFFFAOYSA-N n',n'-diethylethane-1,2-diamine Chemical compound CCN(CC)CCN UDGSVBYJWHOHNN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1427377 N - (Aminoalkyl) - benzamides SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE - DEFRANCE 8 Nov 1973 [9 Nov 1972] 51888/73 Heading C2C Compounds IV in which R 1 is H or alkyl, R 2 is NH 2 , NO 2 , benzylamino tritylamino or acylamino, R 3 and R 4 are H or alkyl, W is alkylene and X is H or halogen are prepared by reacting compound II in which COY represents a carboxyl group or a reactive derivative thereof with an amine R 5 R 6 C=N-W-NR 3 R 4 (in which R 5 and R 6 are each a residue of a carboxylic acid from which the terminal carboxyl group is removed) to form a novel intermediate III in which A represents or or an isomer thereof which is hydrolysed. Compounds IV (R 2 is other than NH 2 ) are converted to compound IV (R 2 =NH 2 ) by hydrogenation or hydrolysis. Compounds IV prepared are those in which R 1 is methyl, R 3 and R 4 are ethyl, W is ethylene, X is chlorine and R 2 is nitro, amino, acetylamino or benzylamino. N- (2 - diethylaminoethyl) - 2 - methoxy - 4 - aminobenzamide is also prepared and is chlorinated to give the corresponding 5-chloro compound. N - (4 - Oxo - 2 - butylidene); N - (benzylidene)- N - (2 - hydroxy - benzylidene)- and N - (1- carbethoxyethylidene)- N<SP>1</SP>,N<SP>1</SP> - diethyl - ethylenediamine are prepared by reacting N,N-diethylethylenediamine with the appropriate ketone.
[GB1427377A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11270872A JPS4970943A (en) | 1972-11-09 | 1972-11-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38498L true IE38498L (en) | 1974-05-09 |
| IE38498B1 IE38498B1 (en) | 1978-03-29 |
Family
ID=14593496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE200473A IE38498B1 (en) | 1972-11-09 | 1973-11-07 | Preparation of substituted benzamides |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS4970943A (en) |
| AR (1) | AR216036A1 (en) |
| AT (1) | AT345799B (en) |
| CA (1) | CA1001169A (en) |
| DE (1) | DE2355365A1 (en) |
| ES (1) | ES420366A1 (en) |
| FI (1) | FI59989C (en) |
| FR (1) | FR2206314B1 (en) |
| GB (1) | GB1427377A (en) |
| IE (1) | IE38498B1 (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1407055A (en) * | 1963-03-05 | 1965-07-30 | Ile De France | New process for the preparation of substituted benzamides |
-
1972
- 1972-11-09 JP JP11270872A patent/JPS4970943A/ja active Pending
-
1973
- 1973-11-06 DE DE19732355365 patent/DE2355365A1/en not_active Withdrawn
- 1973-11-07 FI FI344573A patent/FI59989C/en active
- 1973-11-07 IE IE200473A patent/IE38498B1/en unknown
- 1973-11-08 AR AR25090173A patent/AR216036A1/en active
- 1973-11-08 AT AT938773A patent/AT345799B/en not_active IP Right Cessation
- 1973-11-08 ES ES420366A patent/ES420366A1/en not_active Expired
- 1973-11-08 GB GB5188873A patent/GB1427377A/en not_active Expired
- 1973-11-08 FR FR7339739A patent/FR2206314B1/fr not_active Expired
- 1973-11-09 CA CA185,427A patent/CA1001169A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES420366A1 (en) | 1976-04-16 |
| FR2206314B1 (en) | 1978-07-13 |
| AT345799B (en) | 1978-10-10 |
| ATA938773A (en) | 1978-02-15 |
| AR216036A1 (en) | 1979-11-30 |
| CA1001169A (en) | 1976-12-07 |
| IE38498B1 (en) | 1978-03-29 |
| GB1427377A (en) | 1976-03-10 |
| DE2355365A1 (en) | 1974-05-22 |
| FI59989C (en) | 1981-11-10 |
| FI59989B (en) | 1981-07-31 |
| JPS4970943A (en) | 1974-07-09 |
| FR2206314A1 (en) | 1974-06-07 |
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