IE38551L - Imidazole derivatives. - Google Patents
Imidazole derivatives.Info
- Publication number
- IE38551L IE38551L IE215473A IE215473A IE38551L IE 38551 L IE38551 L IE 38551L IE 215473 A IE215473 A IE 215473A IE 215473 A IE215473 A IE 215473A IE 38551 L IE38551 L IE 38551L
- Authority
- IE
- Ireland
- Prior art keywords
- imidazole derivatives
- dec
- compounds
- formula
- novel
- Prior art date
Links
- 150000002460 imidazoles Chemical class 0.000 title abstract 3
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1421787 Imidazole derivatives BEECHAM GROUP Ltd 12 Dec 1973 [1 Dec 1972 23 Feb 1973] 55506/72 and 9134/73 Heading C2C Novel imidazole derivatives of the formula wherein R 1 is acetyl or propionyl and R 2 is C 1-12 alkyl, C 2-12 alkenyl, C 3-6 cycloalkyl, C 5-6 cycloalkenyl or aromatic groups containing 1 or 2 nitrogen, sulphur or oxygen atoms, are prepared by acylating the corresponding compounds of the above formula in which R 1 is H. Pharmaceutical compositions suitable for oral or parenteral administration, contain the above novel compounds together with pharmaceutically acceptable carriers. The compounds possess anti-inflammatory activity.
[GB1421787A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5550672 | 1972-12-01 | ||
| GB913473A GB1421787A (en) | 1972-12-01 | 1973-02-23 | Substituted imidazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38551L true IE38551L (en) | 1974-06-01 |
| IE38551B1 IE38551B1 (en) | 1978-04-12 |
Family
ID=26242727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE215473A IE38551B1 (en) | 1972-12-01 | 1973-11-28 | Substituted imidazoles |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS4986367A (en) |
| DE (1) | DE2358509A1 (en) |
| FR (1) | FR2208667B1 (en) |
| GB (1) | GB1421787A (en) |
| IE (1) | IE38551B1 (en) |
| NL (1) | NL7316385A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100538958B1 (en) * | 1999-09-20 | 2005-12-26 | 닛뽕소다 가부시키가이샤 | Processes for the preparation of 4(5)-amino-5(4)-carboxamidoimidazoles and intermediates thereof |
-
1973
- 1973-02-23 GB GB913473A patent/GB1421787A/en not_active Expired
- 1973-11-23 DE DE19732358509 patent/DE2358509A1/en active Pending
- 1973-11-28 IE IE215473A patent/IE38551B1/en unknown
- 1973-11-28 FR FR7342295A patent/FR2208667B1/fr not_active Expired
- 1973-11-29 NL NL7316385A patent/NL7316385A/xx unknown
- 1973-12-01 JP JP48135990A patent/JPS4986367A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2208667B1 (en) | 1977-11-04 |
| GB1421787A (en) | 1976-01-21 |
| NL7316385A (en) | 1974-06-05 |
| IE38551B1 (en) | 1978-04-12 |
| DE2358509A1 (en) | 1974-06-06 |
| FR2208667A1 (en) | 1974-06-28 |
| JPS4986367A (en) | 1974-08-19 |
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