IE40593L - Piperazine derivatives - Google Patents

Piperazine derivatives

Info

Publication number
IE40593L
IE40593L IE750254A IE25475A IE40593L IE 40593 L IE40593 L IE 40593L IE 750254 A IE750254 A IE 750254A IE 25475 A IE25475 A IE 25475A IE 40593 L IE40593 L IE 40593L
Authority
IE
Ireland
Prior art keywords
piperazine derivatives
beta
us3919230a
chloromethylnaphthalene
derivates
Prior art date
Application number
IE750254A
Other versions
IE40593B1 (en
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of IE40593L publication Critical patent/IE40593L/en
Publication of IE40593B1 publication Critical patent/IE40593B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

beta -Naphthylmethyl piperazinyl derivates having anti-Parkinsonism activity prepared by condensation of beta -chloromethylnaphthalene with the appropriate substituted piperazine. [US3919230A]
IE254/75A 1974-02-07 1975-02-07 Novel piperazine derivatives and compositions containing them for treating parkinson's disease IE40593B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US440431A US3919230A (en) 1974-02-07 1974-02-07 {62 -Naphthylmethyl piperazinyl derivatives

Publications (2)

Publication Number Publication Date
IE40593L true IE40593L (en) 1975-08-07
IE40593B1 IE40593B1 (en) 1979-07-04

Family

ID=23748733

Family Applications (1)

Application Number Title Priority Date Filing Date
IE254/75A IE40593B1 (en) 1974-02-07 1975-02-07 Novel piperazine derivatives and compositions containing them for treating parkinson's disease

Country Status (16)

Country Link
US (1) US3919230A (en)
JP (1) JPS50108278A (en)
AU (1) AU501049B2 (en)
BE (1) BE825178A (en)
CA (1) CA1042434A (en)
CH (1) CH616678A5 (en)
DE (1) DE2505002A1 (en)
ES (1) ES434433A1 (en)
FR (1) FR2260353B1 (en)
GB (1) GB1449802A (en)
HU (1) HU171352B (en)
IE (1) IE40593B1 (en)
IL (1) IL46568A (en)
LU (1) LU71803A1 (en)
NL (1) NL7501362A (en)
ZA (1) ZA75160B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130646A (en) * 1975-07-25 1978-12-19 E. R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof
JPS52133993A (en) * 1976-04-29 1977-11-09 Takeda Chem Ind Ltd 1.2-dihydronaphthalene derivatives and method of preparing the same
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US6335343B1 (en) 1999-03-03 2002-01-01 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CN107652156B (en) * 2017-11-18 2023-11-10 辽宁科技学院 Crystallization method and device of beta-methylnaphthalene

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL127996C (en) * 1963-11-19

Also Published As

Publication number Publication date
US3919230A (en) 1975-11-11
ZA75160B (en) 1976-01-28
IL46568A0 (en) 1975-04-25
HU171352B (en) 1977-12-28
NL7501362A (en) 1975-08-11
IE40593B1 (en) 1979-07-04
FR2260353A1 (en) 1975-09-05
AU501049B2 (en) 1979-06-07
BE825178A (en) 1975-08-04
GB1449802A (en) 1976-09-15
FR2260353B1 (en) 1980-01-04
DE2505002A1 (en) 1975-08-14
CA1042434A (en) 1978-11-14
IL46568A (en) 1979-01-31
JPS50108278A (en) 1975-08-26
LU71803A1 (en) 1975-06-24
ES434433A1 (en) 1976-11-16
CH616678A5 (en) 1980-04-15
AU7784075A (en) 1976-08-05

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