IE41673L - Fused pyrimidines - Google Patents
Fused pyrimidinesInfo
- Publication number
- IE41673L IE41673L IE740781A IE78174A IE41673L IE 41673 L IE41673 L IE 41673L IE 740781 A IE740781 A IE 740781A IE 78174 A IE78174 A IE 78174A IE 41673 L IE41673 L IE 41673L
- Authority
- IE
- Ireland
- Prior art keywords
- alkoxy
- alkyl
- composition
- fused pyrimidines
- gb1458205a
- Prior art date
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 methylenedioxy Chemical group 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 239000000150 Sympathomimetic Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 208000006218 bradycardia Diseases 0.000 abstract 1
- 230000036471 bradycardia Effects 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1458205 Pharmaceutical compositions PFIZER Inc 3 Dec 1973 [13 April 1973] 55900/73 Heading A5B [Also in Division C2] Compounds I, II, III, IV and their cationic salts in which R‹ is OH, alkoxy, NH 2 or NHOH, R 1 is H, alkyl or phenyl and each of R 2 , R 3 , R 4 and R 5 is H, halogen, alkyl or alkoxy and in addition R 2 and R 3 or R 3 and R 4 may be methylenedioxy or ethylenedioxy have anti-allergy properties and from with a carrier a pharmaceutical composition which may be administered orally, parenterally or by inhalation. The composition may also contain theophylline or sympathomimetic amines. Ethyl 7, 8-dimethoxy- 4 - oxo - 3H pyrimido[4, 5 -6 ]- quinoline-2-carboxylate causes hypertension and bradycardia in dogs.
[GB1458205A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35102573A | 1973-04-13 | 1973-04-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41673L true IE41673L (en) | 1974-10-13 |
| IE41673B1 IE41673B1 (en) | 1980-02-27 |
Family
ID=23379271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE781/74A IE41673B1 (en) | 1973-04-13 | 1974-04-11 | Fused pyrimidines and preparation thereof |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5018481A (en) |
| AR (3) | AR205556A1 (en) |
| AT (1) | AT342596B (en) |
| BE (1) | BE813571A (en) |
| BG (1) | BG25988A3 (en) |
| CA (1) | CA1027945A (en) |
| CH (1) | CH619950A5 (en) |
| DD (1) | DD111207A5 (en) |
| DE (1) | DE2418498A1 (en) |
| DK (1) | DK142621B (en) |
| ES (1) | ES425238A1 (en) |
| FI (1) | FI55658C (en) |
| FR (1) | FR2225166B1 (en) |
| GB (1) | GB1458205A (en) |
| HU (1) | HU171157B (en) |
| IE (1) | IE41673B1 (en) |
| IL (1) | IL44569A (en) |
| LU (1) | LU69855A1 (en) |
| NL (1) | NL170285C (en) |
| NO (1) | NO139735C (en) |
| RO (1) | RO64918A (en) |
| YU (1) | YU36960B (en) |
| ZA (1) | ZA742351B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4011324A (en) * | 1976-01-20 | 1977-03-08 | Pfizer Inc. | Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents |
| DE2757915A1 (en) * | 1976-12-28 | 1978-07-06 | Mitsubishi Yuka Pharma | PYRIMIDOCHINOXALINE DERIVATIVES, METHOD FOR MANUFACTURING THE SAME AND MEDICINAL PRODUCTS FOR THE TREATMENT OF ALLERGIC ASTHMA |
| JPS59210071A (en) * | 1982-12-30 | 1984-11-28 | バイオメジヤ−・インコ−ポレ−テツド | Antiviral compound |
| ES2058527T3 (en) * | 1988-06-16 | 1994-11-01 | Smith Kline French Lab | CONDENSED DERIVATIVES OF PIRIMIDINE PROCEDURE AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. |
| FR2682378B1 (en) * | 1991-10-10 | 1995-04-07 | Bellon Laboratoires | NOVEL DERIVATIVES OF FLUOROQUINOLEINE ACID CARBOXYLIC-3 AND THEIR PREPARATION. |
| FR2703681B1 (en) * | 1993-04-08 | 1995-05-12 | Bellon Labor Sa Roger | PROCESS FOR PREPARING FLUORO-6-HALOGENO-2 QUINOLEINE |
| AU2003284217A1 (en) * | 2002-10-16 | 2004-05-04 | Smithkline Beecham Corporation | Chemical compounds |
| WO2021065250A1 (en) * | 2019-09-30 | 2021-04-08 | 富士フイルム株式会社 | Colored resin particle dispersion, ink, ink set, method for inkjet textile printing, method for producing oil-soluble dye, and textile-printed article |
-
1973
- 1973-12-03 GB GB5590073A patent/GB1458205A/en not_active Expired
-
1974
- 1974-01-01 AR AR257178A patent/AR205556A1/en active
- 1974-01-01 AR AR257177A patent/AR207459A1/en active
- 1974-01-01 AR AR253237A patent/AR205342A1/en active
- 1974-04-04 IL IL44569A patent/IL44569A/en unknown
- 1974-04-04 NO NO741231A patent/NO139735C/en unknown
- 1974-04-10 NL NLAANVRAGE7404894,A patent/NL170285C/en not_active IP Right Cessation
- 1974-04-10 DK DK200974AA patent/DK142621B/en not_active IP Right Cessation
- 1974-04-10 YU YU1016/74A patent/YU36960B/en unknown
- 1974-04-10 FI FI1095/74A patent/FI55658C/en active
- 1974-04-10 ES ES425238A patent/ES425238A1/en not_active Expired
- 1974-04-11 CH CH511074A patent/CH619950A5/en not_active IP Right Cessation
- 1974-04-11 CA CA197,461A patent/CA1027945A/en not_active Expired
- 1974-04-11 DD DD177859A patent/DD111207A5/xx unknown
- 1974-04-11 DE DE2418498A patent/DE2418498A1/en not_active Ceased
- 1974-04-11 ZA ZA00742351A patent/ZA742351B/en unknown
- 1974-04-11 IE IE781/74A patent/IE41673B1/en unknown
- 1974-04-11 BE BE1005874A patent/BE813571A/en not_active IP Right Cessation
- 1974-04-12 LU LU69855A patent/LU69855A1/xx unknown
- 1974-04-12 FR FR7413092A patent/FR2225166B1/fr not_active Expired
- 1974-04-12 HU HU74PI00000413A patent/HU171157B/en unknown
- 1974-04-13 JP JP49041582A patent/JPS5018481A/ja active Pending
- 1974-04-13 BG BG026410A patent/BG25988A3/en unknown
- 1974-04-13 RO RO7478412A patent/RO64918A/en unknown
- 1974-04-16 AT AT315174A patent/AT342596B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE813571A (en) | 1974-10-11 |
| NO139735C (en) | 1979-05-02 |
| NO741231L (en) | 1974-10-15 |
| RO64918A (en) | 1980-01-15 |
| AR205556A1 (en) | 1976-05-14 |
| FR2225166B1 (en) | 1977-06-03 |
| ES425238A1 (en) | 1976-05-16 |
| AR205342A1 (en) | 1976-04-30 |
| YU36960B (en) | 1984-08-31 |
| FR2225166A1 (en) | 1974-11-08 |
| AU6750074A (en) | 1975-10-09 |
| DK142621B (en) | 1980-12-01 |
| YU101674A (en) | 1982-06-18 |
| DE2418498A1 (en) | 1974-11-07 |
| GB1458205A (en) | 1976-12-08 |
| ATA315174A (en) | 1977-08-15 |
| ZA742351B (en) | 1975-04-30 |
| DK142621C (en) | 1981-08-03 |
| IL44569A (en) | 1979-05-31 |
| CA1027945A (en) | 1978-03-14 |
| FI55658C (en) | 1979-09-10 |
| IE41673B1 (en) | 1980-02-27 |
| NL170285B (en) | 1982-05-17 |
| AT342596B (en) | 1978-04-10 |
| BG25988A3 (en) | 1979-01-12 |
| IL44569A0 (en) | 1974-06-30 |
| NL7404894A (en) | 1974-10-15 |
| CH619950A5 (en) | 1980-10-31 |
| HU171157B (en) | 1977-11-28 |
| NO139735B (en) | 1979-01-22 |
| JPS5018481A (en) | 1975-02-26 |
| DD111207A5 (en) | 1975-02-05 |
| LU69855A1 (en) | 1974-11-21 |
| NL170285C (en) | 1982-10-18 |
| FI55658B (en) | 1979-05-31 |
| AR207459A1 (en) | 1976-10-08 |
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