IE42564L - Thieno-benzodiazepine derivatives - Google Patents

Thieno-benzodiazepine derivatives

Info

Publication number
IE42564L
IE42564L IE752565A IE256575A IE42564L IE 42564 L IE42564 L IE 42564L IE 752565 A IE752565 A IE 752565A IE 256575 A IE256575 A IE 256575A IE 42564 L IE42564 L IE 42564L
Authority
IE
Ireland
Prior art keywords
thieno
benzodiazepine derivatives
piperazino
benzodiazepines
amino
Prior art date
Application number
IE752565A
Other versions
IE42564B1 (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE42564(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to IE1607/79A priority Critical patent/IE42565B1/en
Publication of IE42564L publication Critical patent/IE42564L/en
Publication of IE42564B1 publication Critical patent/IE42564B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Thieno1,5!benzodiazepines having useful CNS activity containing the novel tricyclic ring system : the 10-position being substituted by an amino, preferably a piperazino, group. Thieno¢1,5!benzodiazepines having useful CNS activity containing the novel tricyclic ring system : the 10-position being substituted by an amino, preferably a piperazino, group. [CA1075687A]
IE2565/75A 1974-11-26 1975-11-25 Benzodiazepine derivatives IE42564B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1607/79A IE42565B1 (en) 1974-11-26 1975-11-25 Thieno (1,5) benzodiazepine intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
IE42564L true IE42564L (en) 1976-05-26
IE42564B1 IE42564B1 (en) 1980-09-10

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2565/75A IE42564B1 (en) 1974-11-26 1975-11-25 Benzodiazepine derivatives

Country Status (30)

Country Link
JP (1) JPS6044314B2 (en)
AR (1) AR221203A1 (en)
AT (1) AT351547B (en)
AU (1) AU506340B2 (en)
BE (1) BE835932A (en)
BG (1) BG29573A3 (en)
CA (1) CA1075687A (en)
CH (2) CH613454A5 (en)
CS (1) CS236753B2 (en)
DD (1) DD123343A5 (en)
DE (1) DE2552403C2 (en)
DK (1) DK146887C (en)
ES (1) ES443011A1 (en)
FR (1) FR2292479A1 (en)
GB (1) GB1533235A (en)
HK (1) HK58681A (en)
HU (1) HU172493B (en)
IE (1) IE42564B1 (en)
IL (1) IL48502A (en)
KE (1) KE3163A (en)
MY (1) MY8200149A (en)
NL (1) NL186088C (en)
NZ (1) NZ179335A (en)
PH (2) PH11669A (en)
PL (1) PL100135B1 (en)
RO (1) RO69912A (en)
SE (2) SE421209B (en)
SU (2) SU629879A3 (en)
YU (1) YU298375A (en)
ZA (1) ZA757344B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
DE69329887T2 (en) * 1992-05-29 2001-05-23 Eli Lilly And Co., Ltd. Thienobenzodiazepine derivatives for the treatment of disorders of the central nervous system
WO1997016430A1 (en) * 1995-11-01 1997-05-09 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
AU739385B2 (en) * 1997-09-02 2001-10-11 Mitsubishi Pharma Corporation Condensed thiophene compounds and pharmaceutical use thereof
RU2185383C1 (en) * 2001-05-22 2002-07-20 Институт молекулярной генетики РАН 2-methyl-4-(4-methyl-1-piperazinyl)-10h-thieno-[2,3-b][1,5]benzodiazepine high-labeled with tritium
PL199016B1 (en) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Method of manufacture of alanzapine, new derivative of n-demethyl olanzapine and method of manufacture of new derivative of n-demethyl olanzapine
SI21270A (en) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Crystal forms of olanzapine and procedures for their preparation
DE10301923B3 (en) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Process and intermediates for the production of olanzapine
EP1720885A1 (en) * 2004-01-27 2006-11-15 Synthon B.V. A process for making olanzapine in a polymorph form i
AR048272A1 (en) 2004-03-18 2006-04-12 Lek Pharmaceuticals SYNTHESIS OF 2 METHYL - 4- (4- METHYL -1- PIPERAZINIL) - 10 H- TIENO (2,3-B) (1,5) BENZODIAZEPIN AND ITS SALTS, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING IT AND ITS USE IN THE MANUFACTURE OF MEDICINES FOR THE TREATMENT OF MENTAL DISEASES.
KR101216984B1 (en) * 2004-06-30 2013-01-02 아더시스 인코포레이티드 Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
NL7513833A (en) 1976-05-31
AU8685875A (en) 1977-05-26
JPS5176296A (en) 1976-07-01
GB1533235A (en) 1978-11-22
HK58681A (en) 1981-12-04
DK146887B (en) 1984-01-30
DK524175A (en) 1976-05-27
SU629879A3 (en) 1978-10-25
AT351547B (en) 1979-07-25
CH613455A5 (en) 1979-09-28
CA1075687A (en) 1980-04-15
ATA898275A (en) 1979-01-15
SE7812194L (en) 1978-11-27
NL186088B (en) 1990-04-17
ES443011A1 (en) 1977-07-01
AU506340B2 (en) 1979-12-20
YU298375A (en) 1982-10-31
CH613454A5 (en) 1979-09-28
BE835932A (en) 1976-05-25
DE2552403C2 (en) 1986-06-19
PH24534A (en) 1990-08-03
AR221203A1 (en) 1981-01-15
CS236753B2 (en) 1985-05-15
NZ179335A (en) 1978-11-13
RO69912A (en) 1980-08-15
FR2292479A1 (en) 1976-06-25
HU172493B (en) 1978-09-28
SE421209B (en) 1981-12-07
PH11669A (en) 1978-05-19
MY8200149A (en) 1982-12-31
KE3163A (en) 1981-10-16
FR2292479B1 (en) 1978-07-28
BG29573A3 (en) 1980-12-12
DE2552403A1 (en) 1976-08-12
IL48502A0 (en) 1976-01-30
DD123343A5 (en) 1976-12-12
ZA757344B (en) 1976-11-24
IL48502A (en) 1980-01-31
PL100135B1 (en) 1978-09-30
NL186088C (en) 1990-09-17
DK146887C (en) 1984-07-09
SE429045B (en) 1983-08-08
IE42564B1 (en) 1980-09-10
SU626702A3 (en) 1978-09-30
SE7513185L (en) 1976-05-27
JPS6044314B2 (en) 1985-10-02

Similar Documents

Publication Publication Date Title
CA1007200A (en) Bottle carrier
IE42109L (en) Benzimidazole-2-carbamate derivatives.
SE7513185L (en) PROCEDURE FOR THE PREPARATION OF TIENOBENSODIAZEPINES
IE43567L (en) Tricyclic n-containing derivatives.
AU475718B2 (en) 9-(SUBSTITUTED AMINO) IMIDAZO [4,5-f] QUINOLINES
IE40141L (en) Benzimidazole-2-carbamate derivatives
IE38942L (en) DIBENZO [a,d] CYCLOHEPTENE DERIVATIVES
AU473160B2 (en) 9-(SUBSTITUTED AMINO) IMIDAZO [4,5-f] QUINOLINE
CA1007199A (en) Bottle carrier
ZA743647B (en) 5h-<1> benzopyrano <3,4-d> pyridines
YU39716B (en) Process for obtaining thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine derivatives
CA1013357A (en) Tricyclic arylalkylene lactamimides
IE40051B1 (en) 7-(-(cyanomethyl-aryl)-acteamido)-cephalosporins
AU528706B2 (en) 7,8,9,10-tetrahydrothieno(3,2-e)pyrido(4,3-b)indole derivatives
AU6700674A (en) Method for the preparation of phthalazino [2,3-b] phthalazine-5 (14h), 12(7h)-dione
AU478296B2 (en) SUBSTITUTED DIBENZO [b,f] THIEPINS
AU488550B2 (en) Novel 4h-s-triazolo [4,3-a] [1,5] benzodiazepin-5-ones
AU457549B2 (en) 4h-s-triazalo 4,3-2 [1,4] benzodiazepines
AU513593B2 (en) Thermoplastic parison with annular, integral supporting ring
AU461960B2 (en) 1,3-DIMETHYL-5-METHYLAMINO-8-PHENYL-PYRAZOLO [4,3-e][1,4] DIAZEPINE
AU485253B2 (en) 11H-PYRIMIDO [4,5-b][1,4] BENZODIAZEPINES
AU488547B2 (en) Sulphur ring compounds
AU481064B2 (en) 5h-[1] benzopyrano [3,4-d] pyridines
CA1020553A (en) Processes for purification of derivatives of 1,4-benzodiazepin-2-one
CA1016944A (en) Method for the preparation of phthalazino (2,3,-b) phthalazine-5(14h), 12(7h)-dione