IE43917L - 4-(9, 10-DIHYDRO-4H-BENZO [4,5] CYCLOHEPTA [1,2-b]¹THIOPHEN-4-YLIDENE) PIPERIDINES - Google Patents

4-(9, 10-DIHYDRO-4H-BENZO [4,5] CYCLOHEPTA [1,2-b]¹THIOPHEN-4-YLIDENE) PIPERIDINES

Info

Publication number
IE43917L
IE43917L IE761353A IE135376A IE43917L IE 43917 L IE43917 L IE 43917L IE 761353 A IE761353 A IE 761353A IE 135376 A IE135376 A IE 135376A IE 43917 L IE43917 L IE 43917L
Authority
IE
Ireland
Prior art keywords
ylidene
dihydro
benzo
1thiophen
cyclohepta
Prior art date
Application number
IE761353A
Other versions
IE43917B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH817475A external-priority patent/CH613204A5/en
Priority claimed from CH817375A external-priority patent/CH615927A5/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE43917L publication Critical patent/IE43917L/en
Publication of IE43917B1 publication Critical patent/IE43917B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Case 100-4362 n4-(9,10-Dihydro-4H-Benzo4,5!Cyclcohepta1,2-b!Thiophen- 4-Ylidene)Piperidine Compounds This invention provides new compounds of formula I, (I) wherein R1 is hydrogen or alkyl, and R2 is alkyl, useful as analgesics. Case 100-4362 n4-(9,10-Dihydro-4H-Benzo¢4,5!Cyclcohepta¢1,2-b!Thiophen- 4-Ylidene)Piperidine Compounds This invention provides new compounds of formula I, (I) wherein R1 is hydrogen or alkyl, and R2 is alkyl, useful as analgesics. [CA1085403A]
IE1353/76A 1975-06-24 1976-06-22 4-(9,10-dihydro-4h-benzo/4,5/cyclohepta/1,2-b/thiophen-4-ylidine piperidines IE43917B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH817475A CH613204A5 (en) 1975-06-24 1975-06-24 Process for the preparation of novel benzocycloheptathiophene derivatives
CH817375A CH615927A5 (en) 1975-06-24 1975-06-24 Process for the preparation of novel benzocycloheptathiophene derivatives

Publications (2)

Publication Number Publication Date
IE43917L true IE43917L (en) 1976-12-24
IE43917B1 IE43917B1 (en) 1981-07-01

Family

ID=25702907

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1353/76A IE43917B1 (en) 1975-06-24 1976-06-22 4-(9,10-dihydro-4h-benzo/4,5/cyclohepta/1,2-b/thiophen-4-ylidine piperidines

Country Status (17)

Country Link
JP (1) JPS523075A (en)
AU (1) AU508585B2 (en)
CA (1) CA1085403A (en)
DE (1) DE2626583A1 (en)
DK (1) DK267976A (en)
ES (1) ES449099A1 (en)
FI (1) FI761721A7 (en)
FR (1) FR2316949A1 (en)
GB (1) GB1554427A (en)
IE (1) IE43917B1 (en)
IL (1) IL49862A (en)
NL (1) NL7606700A (en)
NO (1) NO762085L (en)
NZ (1) NZ181236A (en)
PH (1) PH14805A (en)
PT (1) PT65264B (en)
SE (1) SE7606877L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597963B2 (en) * 1977-06-28 1984-02-22 沖電気工業株式会社 Circular interpolation circuit in numerical control
EP0047226B1 (en) * 1980-09-02 1985-05-15 Sandoz Ag Piperidylidene derivatives, their production and pharmaceutical compositions containing them
JPS63205706A (en) * 1987-02-23 1988-08-25 Yaskawa Electric Mfg Co Ltd Arc machining control method
KR20010005791A (en) * 1997-04-03 2001-01-15 아베르그, 에이. 케이 Benzocycloheptathiophene compounds
NZ587050A (en) * 2008-01-30 2012-08-31 Nippon Zoki Pharmaceutical Co Compounds featuring a tricyclic group double bonded to a piperidine group, as an antihistamine
JP5083989B2 (en) * 2008-11-20 2012-11-28 日本臓器製薬株式会社 Medicaments containing piperidine derivatives
CN113227037A (en) * 2018-09-30 2021-08-06 北京生命科学研究所 Monohalogen or methyl substituted 5-HT2B antagonists with increased activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1437412A (en) * 1963-12-19 1966-05-06 Sandoz Sa New benzo-cyclohepta-thiophenes and their preparation

Also Published As

Publication number Publication date
AU1520376A (en) 1978-01-05
NO762085L (en) 1976-12-28
PT65264A (en) 1976-07-01
PH14805A (en) 1981-12-14
NL7606700A (en) 1976-12-28
FR2316949A1 (en) 1977-02-04
IL49862A0 (en) 1976-08-31
FI761721A7 (en) 1976-12-25
DK267976A (en) 1976-12-25
ES449099A1 (en) 1978-03-01
CA1085403A (en) 1980-09-09
PT65264B (en) 1978-03-24
NZ181236A (en) 1978-06-20
GB1554427A (en) 1979-10-24
DE2626583A1 (en) 1977-01-13
IL49862A (en) 1980-11-30
SE7606877L (en) 1976-12-25
JPS523075A (en) 1977-01-11
IE43917B1 (en) 1981-07-01
AU508585B2 (en) 1980-03-27
FR2316949B1 (en) 1979-10-12

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