IE44862L - Cinnamides - Google Patents

Cinnamides

Info

Publication number
IE44862L
IE44862L IE770212A IE21277A IE44862L IE 44862 L IE44862 L IE 44862L IE 770212 A IE770212 A IE 770212A IE 21277 A IE21277 A IE 21277A IE 44862 L IE44862 L IE 44862L
Authority
IE
Ireland
Prior art keywords
formula
acid
compounds
image
cinnamides
Prior art date
Application number
IE770212A
Other versions
IE44862B1 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE44862L publication Critical patent/IE44862L/en
Publication of IE44862B1 publication Critical patent/IE44862B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

The compounds of the formula I are prepared by reacting a compound of the formula III R.NH.W, in which W denotes hydrogen or a group which can be eliminated, with an acid of the formula II <IMAGE> . Instead of the free acid, an active derivative of this acid can be used. The substituents in the formulae have the meanings given in Claim 1. The compounds of the formula I possess useful pharmacological properties. <IMAGE> [GB1568401A]
IE212/77A 1976-02-03 1977-02-02 Biologically active amides IE44862B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB4168/76A GB1568401A (en) 1976-02-03 1976-02-03 Biologically active amides
GB417076 1976-02-03
GB416976 1976-02-03
US71213476A 1976-08-06 1976-08-06
US71231876A 1976-08-06 1976-08-06
US71213576A 1976-08-06 1976-08-06

Publications (2)

Publication Number Publication Date
IE44862L true IE44862L (en) 1977-08-03
IE44862B1 IE44862B1 (en) 1982-04-21

Family

ID=27546490

Family Applications (1)

Application Number Title Priority Date Filing Date
IE212/77A IE44862B1 (en) 1976-02-03 1977-02-02 Biologically active amides

Country Status (20)

Country Link
JP (1) JPS6056700B2 (en)
AR (1) AR218865A1 (en)
AT (1) AT363926B (en)
BE (1) BE851020A (en)
CA (1) CA1109076A (en)
CH (1) CH634551A5 (en)
CS (2) CS245756B2 (en)
DD (1) DD130349A5 (en)
DE (1) DE2704365C2 (en)
DK (1) DK43177A (en)
FI (1) FI69625C (en)
FR (1) FR2340303A1 (en)
GB (1) GB1568401A (en)
GR (1) GR66474B (en)
HU (1) HU175435B (en)
IE (1) IE44862B1 (en)
IL (1) IL51373A (en)
NL (1) NL7701088A (en)
PL (2) PL119314B1 (en)
SE (2) SE436870B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0714871B2 (en) * 1989-02-02 1995-02-22 大正製薬株式会社 Muscle relaxant
DE19931116A1 (en) * 1999-07-06 2001-01-11 Bayer Ag Process for the production of phenethylamines and new chemical compounds
CN104513172B (en) * 2013-09-30 2018-02-02 天士力医药集团股份有限公司 Acid amides alkaloid, preparation method and its medicinal usage containing trifluoromethyl
CN104432097B (en) * 2014-12-16 2016-08-17 广州渔夫堡医药科技有限公司 A kind of natural enriching substance of alleviating physical fatigue

Also Published As

Publication number Publication date
CH634551A5 (en) 1983-02-15
NL7701088A (en) 1977-08-05
SE7701107L (en) 1977-08-04
DK43177A (en) 1977-08-04
AR218865A1 (en) 1980-07-15
SE8300432D0 (en) 1983-01-28
IE44862B1 (en) 1982-04-21
HU175435B (en) 1980-07-28
IL51373A0 (en) 1977-04-29
GB1568401A (en) 1980-05-29
CS245758B2 (en) 1986-10-16
SE436870B (en) 1985-01-28
FR2340303B1 (en) 1979-04-13
AT363926B (en) 1981-09-10
FI69625C (en) 1986-03-10
ATA65277A (en) 1981-02-15
DE2704365C2 (en) 1986-03-20
PL119716B1 (en) 1982-01-30
SE8300432L (en) 1983-01-28
CS245756B2 (en) 1986-10-16
GR66474B (en) 1981-03-23
FI770365A7 (en) 1977-08-04
FI69625B (en) 1985-11-29
PL119314B1 (en) 1981-12-31
CA1109076A (en) 1981-09-15
BE851020A (en) 1977-08-02
JPS6056700B2 (en) 1985-12-11
IL51373A (en) 1981-12-31
DE2704365A1 (en) 1977-08-04
JPS52116437A (en) 1977-09-29
FR2340303A1 (en) 1977-09-02
PL195740A1 (en) 1979-05-07
DD130349A5 (en) 1978-03-22

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