IE45244L - Dibenzopyran derivatives - Google Patents
Dibenzopyran derivativesInfo
- Publication number
- IE45244L IE45244L IE771386A IE138677A IE45244L IE 45244 L IE45244 L IE 45244L IE 771386 A IE771386 A IE 771386A IE 138677 A IE138677 A IE 138677A IE 45244 L IE45244 L IE 45244L
- Authority
- IE
- Ireland
- Prior art keywords
- cis
- hydroxy
- compounds
- gb1582564a
- cyclohexadiene
- Prior art date
Links
- ILAHWRKJUDSMFH-UHFFFAOYSA-N boron tribromide Chemical compound BrB(Br)Br ILAHWRKJUDSMFH-UHFFFAOYSA-N 0.000 abstract 2
- WTEOIRVLGSZEPR-UHFFFAOYSA-N boron trifluoride Chemical compound FB(F)F WTEOIRVLGSZEPR-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 abstract 2
- 125000000081 (C5-C8) cycloalkenyl group Chemical group 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 229910015900 BF3 Inorganic materials 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 229910021627 Tin(IV) chloride Inorganic materials 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
dl-6a,10a-cis-1-Hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a- hexahydro-9H-dibenzo[b,d]pyran-9-ones of the formula <IMAGE> in which R represents C5-C10-alkyl, C5-C10-alkenyl, C5-C8-cycloalkyl or C5-C8-cycloalkenyl, where the hydrogen atoms present in the positions 6a and 10a are arranged in the cis-position to one another. These compounds are obtained by reacting a 1-alkoxy-4-(1-hydroxy-1-methylethyl)-1,4-cyclohexadiene with a resorcinol containing the radical R in the 5-position in the presence of a catalyst from the group consisting of boron tribromide, boron trifluoride, or tin(IV) chloride in an inert organic solvent. The compounds obtained can be used as medicaments for the treatment of anxiety states and depressions.
[GB1582564A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70280676A | 1976-07-06 | 1976-07-06 | |
| US70280976A | 1976-07-06 | 1976-07-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE45244L true IE45244L (en) | 1978-01-06 |
| IE45244B1 IE45244B1 (en) | 1982-07-14 |
Family
ID=27107024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1386/77A IE45244B1 (en) | 1976-07-06 | 1977-07-05 | Dibenzopyrans |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5943466B2 (en) |
| AR (1) | AR213440A1 (en) |
| AT (1) | AT351531B (en) |
| AU (1) | AU511627B2 (en) |
| BG (1) | BG28063A3 (en) |
| CH (1) | CH633786A5 (en) |
| CS (1) | CS193580B2 (en) |
| DD (1) | DD131469A5 (en) |
| DE (1) | DE2729817C2 (en) |
| DK (1) | DK145100C (en) |
| FR (1) | FR2357555A1 (en) |
| GB (1) | GB1582564A (en) |
| GR (1) | GR66415B (en) |
| HU (1) | HU176954B (en) |
| IE (1) | IE45244B1 (en) |
| IL (1) | IL52425A (en) |
| NL (1) | NL7707464A (en) |
| NZ (1) | NZ184528A (en) |
| PL (1) | PL108319B1 (en) |
| SE (1) | SE428018B (en) |
| SU (1) | SU772483A3 (en) |
| YU (1) | YU163477A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4171315A (en) * | 1978-03-31 | 1979-10-16 | Eli Lilly And Company | Preparation of cis-hexahydrodibenzopyranones |
| US4395560A (en) * | 1982-05-24 | 1983-07-26 | Eli Lilly And Company | Preparation of 6a,10a-trans-hexahydrodibenzopyranones |
| CA2638940C (en) * | 2008-08-28 | 2009-09-15 | Dalton Chemical Laboratories Inc. | Improved synthesis of hexahydrodibenzopyranones |
-
1977
- 1977-06-29 GB GB27112/77A patent/GB1582564A/en not_active Expired
- 1977-06-30 IL IL52425A patent/IL52425A/en unknown
- 1977-06-30 NZ NZ184528A patent/NZ184528A/en unknown
- 1977-06-30 SE SE7707631A patent/SE428018B/en not_active IP Right Cessation
- 1977-07-01 AU AU26682/77A patent/AU511627B2/en not_active Expired
- 1977-07-01 YU YU01634/77A patent/YU163477A/en unknown
- 1977-07-01 DE DE2729817A patent/DE2729817C2/en not_active Expired
- 1977-07-01 BG BG036780A patent/BG28063A3/en unknown
- 1977-07-04 AR AR268308A patent/AR213440A1/en active
- 1977-07-04 JP JP52081486A patent/JPS5943466B2/en not_active Expired
- 1977-07-04 CH CH819177A patent/CH633786A5/en not_active IP Right Cessation
- 1977-07-04 PL PL1977199361A patent/PL108319B1/en unknown
- 1977-07-04 SU SU772499310A patent/SU772483A3/en active
- 1977-07-05 HU HU77EI753A patent/HU176954B/en unknown
- 1977-07-05 DK DK301377A patent/DK145100C/en not_active IP Right Cessation
- 1977-07-05 NL NL7707464A patent/NL7707464A/en not_active Application Discontinuation
- 1977-07-05 DD DD7700199897A patent/DD131469A5/en unknown
- 1977-07-05 IE IE1386/77A patent/IE45244B1/en unknown
- 1977-07-05 GR GR53877A patent/GR66415B/el unknown
- 1977-07-05 FR FR7720642A patent/FR2357555A1/en active Granted
- 1977-07-06 CS CS774516A patent/CS193580B2/en unknown
- 1977-07-06 AT AT483477A patent/AT351531B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AR213440A1 (en) | 1979-01-31 |
| ATA483477A (en) | 1979-01-15 |
| SE428018B (en) | 1983-05-30 |
| BG28063A3 (en) | 1980-02-25 |
| IL52425A (en) | 1980-09-16 |
| PL199361A1 (en) | 1978-04-10 |
| DK145100B (en) | 1982-08-30 |
| CH633786A5 (en) | 1982-12-31 |
| IL52425A0 (en) | 1977-08-31 |
| AT351531B (en) | 1979-07-25 |
| DD131469A5 (en) | 1978-06-28 |
| JPS5943466B2 (en) | 1984-10-22 |
| DE2729817A1 (en) | 1978-01-12 |
| JPS537678A (en) | 1978-01-24 |
| PL108319B1 (en) | 1980-04-30 |
| FR2357555B1 (en) | 1980-02-01 |
| IE45244B1 (en) | 1982-07-14 |
| DE2729817C2 (en) | 1982-05-27 |
| SU772483A3 (en) | 1980-10-15 |
| NZ184528A (en) | 1978-09-20 |
| CS193580B2 (en) | 1979-10-31 |
| AU511627B2 (en) | 1980-08-28 |
| GR66415B (en) | 1981-03-20 |
| SE7707631L (en) | 1978-01-07 |
| YU163477A (en) | 1982-06-30 |
| AU2668277A (en) | 1979-01-04 |
| GB1582564A (en) | 1981-01-14 |
| DK145100C (en) | 1983-01-31 |
| FR2357555A1 (en) | 1978-02-03 |
| DK301377A (en) | 1978-01-07 |
| HU176954B (en) | 1981-06-28 |
| NL7707464A (en) | 1978-01-10 |
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