IE780974L - Vaccine for immunotherapy of neoplastic disease - Google Patents
Vaccine for immunotherapy of neoplastic diseaseInfo
- Publication number
- IE780974L IE780974L IE780974A IE97478A IE780974L IE 780974 L IE780974 L IE 780974L IE 780974 A IE780974 A IE 780974A IE 97478 A IE97478 A IE 97478A IE 780974 L IE780974 L IE 780974L
- Authority
- IE
- Ireland
- Prior art keywords
- vaccine
- cells
- tissue
- immunotherapy
- neoplastic disease
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 238000009169 immunotherapy Methods 0.000 title abstract 2
- 230000001613 neoplastic effect Effects 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 210000003850 cellular structure Anatomy 0.000 abstract 2
- WAEMQWOKJMHJLA-UHFFFAOYSA-N Manganese(2+) Chemical compound [Mn+2] WAEMQWOKJMHJLA-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A process for producing a vaccine for use in the immunotherapy of neoplastic disease, said vaccine being produced by: (a) obtaining an amount of cancerous tissue from the patient to be treated and suspending said tissue in an aqueous solution of between about 100 and 150 millimolar sodium chloride and between about 5 and 15 millimolar sodium EDTA, (b) disaggregating the tissue into its component cells; (c) suspending the cells in water: (d) subjecting the suspended cells to hydrodynamic turbulence sufficient to disrupt the cells and detach therefrom the cell components possessing cancer-specific antigens; and (e) contacting and admixing the cell components obtained in step (d) with a source of manganousion to form the vaccine. [IN149012A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89812278A | 1978-04-20 | 1978-04-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE780974L true IE780974L (en) | 1979-10-20 |
| IE47736B1 IE47736B1 (en) | 1984-06-13 |
Family
ID=25408978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE974/78A IE47736B1 (en) | 1978-04-20 | 1978-05-15 | Improvements in or relating to a method of producing a vaccine for use in the immunotherapy of neoplastic disease |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS54154506A (en) |
| AU (1) | AU519008B2 (en) |
| BE (1) | BE867410A (en) |
| DE (1) | DE2822731A1 (en) |
| FR (1) | FR2423223A1 (en) |
| GB (1) | GB1603597A (en) |
| IE (1) | IE47736B1 (en) |
| IN (1) | IN149012B (en) |
| MX (1) | MX5759E (en) |
| NL (1) | NL7805501A (en) |
| PH (1) | PH14990A (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2900184A (en) * | 1983-06-10 | 1984-12-13 | Richard F. Martin | Membrane antigens generated from pooled cells and monoclonal antibodies |
| GB8321009D0 (en) * | 1983-08-04 | 1983-09-07 | New R R C | Immunological compositions |
| DE19519492A1 (en) * | 1995-05-27 | 1996-11-28 | Miele & Cie | Carrier for metal workpieces |
| CN1100569C (en) * | 1997-01-24 | 2003-02-05 | 石桂秀 | Method for preparing tumour vaccinum |
| JP2022546578A (en) * | 2019-09-04 | 2022-11-04 | ブイセル セラピューティックス，インコーポレイテッド | Vaccines for treating cancer and methods for their production by stress reprogramming |
| WO2025028658A1 (en) * | 2023-08-03 | 2025-02-06 | 国立大学法人東京農工大学 | Immunopotentiator and immunopotentiating method, and method for producing aggregate and/or assembly of protein |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3065141A (en) * | 1960-08-24 | 1962-11-20 | Albert E Gessler | Separation of nucleoproteins and nucleic acids from aqueous protein mixtures |
| DE1617865A1 (en) * | 1966-03-12 | 1971-09-02 | Karl Dr Med Theurer | Process for the manufacture of anti-cancer drugs |
| GB1193378A (en) * | 1967-04-11 | 1970-05-28 | Rand Dev Corp | Cancer Antigen Complexes |
| GB1291134A (en) * | 1970-01-21 | 1972-09-27 | Anvar | A process for the production of mammal cell anti-sera |
| US4053586A (en) * | 1971-10-08 | 1977-10-11 | Intermountain Laboratories, Inc. | Preparation for treating squamous cell carcinoma and method for making same |
| ZA782613B (en) * | 1978-05-08 | 1979-12-27 | D Mccollester | Vaccine and method for immunotherapy of neoplastic disease |
-
1978
- 1978-05-11 IN IN358/DEL/78A patent/IN149012B/en unknown
- 1978-05-11 AU AU36059/78A patent/AU519008B2/en not_active Expired
- 1978-05-12 MX MX787089U patent/MX5759E/en unknown
- 1978-05-15 IE IE974/78A patent/IE47736B1/en unknown
- 1978-05-21 PH PH21185A patent/PH14990A/en unknown
- 1978-05-22 NL NL7805501A patent/NL7805501A/en unknown
- 1978-05-23 GB GB21668/78A patent/GB1603597A/en not_active Expired
- 1978-05-24 FR FR7815458A patent/FR2423223A1/en active Granted
- 1978-05-24 BE BE187981A patent/BE867410A/en not_active IP Right Cessation
- 1978-05-24 DE DE19782822731 patent/DE2822731A1/en not_active Withdrawn
- 1978-05-24 JP JP6116378A patent/JPS54154506A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BE867410A (en) | 1978-11-24 |
| IE47736B1 (en) | 1984-06-13 |
| PH14990A (en) | 1982-03-12 |
| IN149012B (en) | 1981-08-15 |
| NL7805501A (en) | 1979-10-23 |
| FR2423223A1 (en) | 1979-11-16 |
| GB1603597A (en) | 1981-11-25 |
| AU519008B2 (en) | 1981-11-05 |
| MX5759E (en) | 1984-06-28 |
| DE2822731A1 (en) | 1979-10-31 |
| JPS54154506A (en) | 1979-12-05 |
| FR2423223B1 (en) | 1983-07-29 |
| AU3605978A (en) | 1979-11-15 |
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