IE831267L - Compostions containing salbutamol - Google Patents
Compostions containing salbutamolInfo
- Publication number
- IE831267L IE831267L IE831267A IE126783A IE831267L IE 831267 L IE831267 L IE 831267L IE 831267 A IE831267 A IE 831267A IE 126783 A IE126783 A IE 126783A IE 831267 L IE831267 L IE 831267L
- Authority
- IE
- Ireland
- Prior art keywords
- salbutanol
- pref
- cellulose
- amt
- esp
- Prior art date
Links
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 title 1
- 229960002052 salbutamol Drugs 0.000 title 1
- 229920002678 cellulose Polymers 0.000 abstract 4
- 239000001913 cellulose Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 239000001856 Ethyl cellulose Substances 0.000 abstract 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229920001249 ethyl cellulose Polymers 0.000 abstract 1
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 1
- 239000001761 ethyl methyl cellulose Substances 0.000 abstract 1
- 235000010944 ethyl methyl cellulose Nutrition 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
- 229920013819 hydroxyethyl ethylcellulose Polymers 0.000 abstract 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 abstract 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
New medicaments are aq. dispersions of one or more cellulose derivs. contg. salbutanol and/or one or more physiologically acceptable salts of salbutanol. Suitable cellulose derivs. are those which form an optically transparent or opalescent dispersion in water. Particularly pref. are ethylcellulose, methylcellulose, ethylmethylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl methylcellulose, hydroxypropylmethylcellulose, hydroxyethyl-ethyl cellulose and carboxymethyl cellulose and its salts. The cellulose deriv. is pref. used in a total amt. of at least 0.1% w/v. For oral formulations, the cellulose deriv. is pref. present in an amt. such as to give a viscosity of 5-10000 (esp. 10-100) cPs. Salbutanol or its salt is pref. present in an amt. of 1-4 (esp.2) mg. per 5 ml., expressed as salbutanol free base. The prepn. pref. has a pH of 3.5. Salbutanol is a beta-stimulant with improved stability.
[FR2527442A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8215502 | 1982-05-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE831267L true IE831267L (en) | 1983-11-27 |
| IE55139B1 IE55139B1 (en) | 1990-06-06 |
Family
ID=10530673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1267/83A IE55139B1 (en) | 1982-05-27 | 1983-05-27 | Compositions containing salbutamol |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPH0629181B2 (en) |
| AT (1) | AT390191B (en) |
| AU (1) | AU567675B2 (en) |
| BE (1) | BE896870A (en) |
| CA (1) | CA1203176A (en) |
| CH (1) | CH656308A5 (en) |
| DE (1) | DE3319356C2 (en) |
| DK (1) | DK167558B1 (en) |
| ES (1) | ES8502336A1 (en) |
| FI (1) | FI81257C (en) |
| FR (1) | FR2527442B1 (en) |
| GR (1) | GR82681B (en) |
| IE (1) | IE55139B1 (en) |
| IL (1) | IL68805A0 (en) |
| IT (1) | IT1174759B (en) |
| LU (1) | LU84828A1 (en) |
| MY (1) | MY8700275A (en) |
| NL (1) | NL192663C (en) |
| NO (1) | NO163166C (en) |
| NZ (1) | NZ204385A (en) |
| PH (1) | PH19601A (en) |
| PT (1) | PT76773B (en) |
| SE (1) | SE454946B (en) |
| ZA (1) | ZA833854B (en) |
| ZW (1) | ZW11883A1 (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3624213A (en) * | 1963-10-30 | 1971-11-30 | Merck & Co Inc | Method of sterilizing aqueous pharmaceutical solutions employing propylene oxide and entrained air |
| GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
| GB1453034A (en) * | 1972-12-15 | 1976-10-20 | Boehringer Sohn Ingelheim | Pharmaceutical composition for treating spasticity |
| JPS5831210B2 (en) * | 1973-04-09 | 1983-07-05 | 武田薬品工業株式会社 | antennae |
| DE2714065A1 (en) * | 1977-03-30 | 1978-10-12 | Boehringer Mannheim Gmbh | INSTILLATION PREPARATION |
-
1983
- 1983-05-20 CH CH2779/83A patent/CH656308A5/en not_active IP Right Cessation
- 1983-05-24 GR GR71454A patent/GR82681B/el unknown
- 1983-05-26 NO NO831875A patent/NO163166C/en not_active IP Right Cessation
- 1983-05-26 FR FR8308722A patent/FR2527442B1/en not_active Expired
- 1983-05-27 FI FI831893A patent/FI81257C/en not_active IP Right Cessation
- 1983-05-27 CA CA000429095A patent/CA1203176A/en not_active Expired
- 1983-05-27 PH PH28974A patent/PH19601A/en unknown
- 1983-05-27 NL NL8301900A patent/NL192663C/en not_active IP Right Cessation
- 1983-05-27 PT PT76773A patent/PT76773B/en unknown
- 1983-05-27 DK DK241783A patent/DK167558B1/en not_active IP Right Cessation
- 1983-05-27 ZA ZA833854A patent/ZA833854B/en unknown
- 1983-05-27 LU LU84828A patent/LU84828A1/en unknown
- 1983-05-27 IT IT48384/83A patent/IT1174759B/en active Protection Beyond IP Right Term
- 1983-05-27 AT AT0195283A patent/AT390191B/en not_active IP Right Cessation
- 1983-05-27 ZW ZW118/83A patent/ZW11883A1/en unknown
- 1983-05-27 JP JP58093896A patent/JPH0629181B2/en not_active Expired - Lifetime
- 1983-05-27 AU AU15039/83A patent/AU567675B2/en not_active Expired
- 1983-05-27 IE IE1267/83A patent/IE55139B1/en not_active IP Right Cessation
- 1983-05-27 NZ NZ204385A patent/NZ204385A/en unknown
- 1983-05-27 IL IL68805A patent/IL68805A0/en not_active IP Right Cessation
- 1983-05-27 BE BE0/210866A patent/BE896870A/en not_active IP Right Cessation
- 1983-05-27 SE SE8303012A patent/SE454946B/en not_active IP Right Cessation
- 1983-05-27 ES ES522752A patent/ES8502336A1/en not_active Expired
- 1983-05-27 DE DE3319356A patent/DE3319356C2/en not_active Expired - Lifetime
-
1987
- 1987-12-30 MY MY275/87A patent/MY8700275A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |