IL102929A - Serum-free medium for mammalian cells - Google Patents

Serum-free medium for mammalian cells

Info

Publication number: IL102929A
Authority: IL; Israel
Prior art keywords: thrombin; medium according; medium; production; insulin
Prior art date: 1992-08-24

Application number

IL10292992A

Other languages

English (en)

Other versions

IL102929A0 (en

Original Assignee

Interpharm Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-08-24

Filing date

1992-08-24

Publication date

1996-11-14

1992-08-24 Application filed by Interpharm Lab Ltd filed Critical Interpharm Lab Ltd

1992-08-24 Priority to IL10292992A priority Critical patent/IL102929A/en

1993-01-31 Publication of IL102929A0 publication Critical patent/IL102929A0/xx

1993-08-23 Priority to CA 2104643 priority patent/CA2104643C/en

1993-08-23 Priority to JP20805393A priority patent/JP4124493B2/ja

1993-08-24 Priority to AT00117026T priority patent/ATE348147T1/de

1993-08-24 Priority to EP19930113502 priority patent/EP0584788B1/de

1993-08-24 Priority to AT93113502T priority patent/ATE226632T1/de

1993-08-24 Priority to DE69332430T priority patent/DE69332430T2/de

1993-08-24 Priority to DE1993634097 priority patent/DE69334097T2/de

1993-08-24 Priority to PT93113502T priority patent/PT584788E/pt

1993-08-24 Priority to ES00117026T priority patent/ES2274756T3/es

1993-08-24 Priority to ES93113502T priority patent/ES2185618T3/es

1993-08-24 Priority to US08/111,428 priority patent/US5641647A/en

1993-08-24 Priority to AU44871/93A priority patent/AU670957B2/en

1993-08-24 Priority to DK93113502T priority patent/DK0584788T3/da

1993-08-24 Priority to EP20000117026 priority patent/EP1045023B1/de

1993-08-24 Priority to DK00117026T priority patent/DK1045023T3/da

1993-08-24 Priority to ZA936192A priority patent/ZA936192B/xx

1993-08-24 Priority to PT00117026T priority patent/PT1045023E/pt

1996-11-14 Publication of IL102929A publication Critical patent/IL102929A/en

2007-02-09 Priority to CY0700004A priority patent/CY2572B1/xx

Links

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210000004962 mammalian cell Anatomy 0.000 title claims abstract description 16
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5412—IL-6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes

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Microbiology (AREA)
General Engineering & Computer Science (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL10292992A 1992-08-24 1992-08-24 Serum-free medium for mammalian cells IL102929A (en)

Priority Applications (19)

Application Number	Priority Date	Filing Date	Title
IL10292992A IL102929A (en)	1992-08-24	1992-08-24	Serum-free medium for mammalian cells
CA 2104643 CA2104643C (en)	1992-08-24	1993-08-23	Serum free medium
JP20805393A JP4124493B2 (ja)	1992-08-24	1993-08-23	無血清培地
PT00117026T PT1045023E (pt)	1992-08-24	1993-08-24	Meio isento de soro
PT93113502T PT584788E (pt)	1992-08-24	1993-08-24	Meio livre de soro para celulas de mamiferos
AU44871/93A AU670957B2 (en)	1992-08-24	1993-08-24	Serum free medium
AT93113502T ATE226632T1 (de)	1992-08-24	1993-08-24	Serumfreies medium für säugetierzellen
DE69332430T DE69332430T2 (de)	1992-08-24	1993-08-24	Serumfreies Medium für Säugetierzellen
DE1993634097 DE69334097T2 (de)	1992-08-24	1993-08-24	Serumfreies Medium für Säugetierzellen
AT00117026T ATE348147T1 (de)	1992-08-24	1993-08-24	Serumfreies medium
ES00117026T ES2274756T3 (es)	1992-08-24	1993-08-24	Medio sin suero.
ES93113502T ES2185618T3 (es)	1992-08-24	1993-08-24	Medio exento de suero para celulas de mamifero.
US08/111,428 US5641647A (en)	1992-08-24	1993-08-24	Serum free medium
EP19930113502 EP0584788B1 (de)	1992-08-24	1993-08-24	Serumfreies Medium für Säugetierzellen
DK93113502T DK0584788T3 (da)	1992-08-24	1993-08-24	Serumfrit medium til mammale celler
EP20000117026 EP1045023B1 (de)	1992-08-24	1993-08-24	Serumfreies Medium
DK00117026T DK1045023T3 (da)	1992-08-24	1993-08-24	Serumfrit medium
ZA936192A ZA936192B (en)	1992-08-24	1993-08-24	Serum free medium.
CY0700004A CY2572B1 (en)	1992-08-24	2007-02-09	Serum free medium

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL10292992A IL102929A (en)	1992-08-24	1992-08-24	Serum-free medium for mammalian cells

Publications (2)

Publication Number	Publication Date
IL102929A0 IL102929A0 (en)	1993-01-31
IL102929A true IL102929A (en)	1996-11-14

Family

ID=11063947

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL10292992A IL102929A (en)	1992-08-24	1992-08-24	Serum-free medium for mammalian cells

Country Status (13)

Country	Link
US (1)	US5641647A (de)
EP (2)	EP0584788B1 (de)
JP (1)	JP4124493B2 (de)
AT (2)	ATE226632T1 (de)
AU (1)	AU670957B2 (de)
CA (1)	CA2104643C (de)
CY (1)	CY2572B1 (de)
DE (2)	DE69332430T2 (de)
DK (2)	DK0584788T3 (de)
ES (2)	ES2274756T3 (de)
IL (1)	IL102929A (de)
PT (2)	PT584788E (de)
ZA (1)	ZA936192B (de)

Families Citing this family (20)

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SE9303601D0 (sv) *	1993-11-01	1993-11-01	Kabi Pharmacia Ab	Improved cell cultivation method and medium
AU4330597A (en) *	1996-08-30	1998-03-19	Life Technologies, Inc.	Serum-free mammalian cell culture medium, and uses thereof
US6692961B1 (en) *	1996-10-11	2004-02-17	Invitrogen Corporation	Defined systems for epithelial cell culture and use thereof
WO1998026084A1 (en) *	1996-12-09	1998-06-18	Wolfgang Andreas Renner	Expression of active interferon beta 1 using recombinant rna replicons
SE9700983D0 (sv) *	1997-03-18	1997-03-18	Ascendia Ab	Stimulering, odling och preservation av pankreas- och andra celler
EP2295540A1 (de) *	1998-11-19	2011-03-16	Organogenesis, Inc.	Biotechnisch konstruiertes Gewebe und Verfahren zu dessen Produktion und Benutzung
UA74557C2 (en)	1999-09-03	2006-01-16	Applied Research Systems	A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
EP1754784A3 (de) *	1999-09-03	2007-02-28	Applied Research Systems ARS Holding N.V.	Verfahren zur Produktion eines heterologen sezernierten Proteins aus auf Mikroträgern gewachsenen Cho-Zellen
US7445924B2 (en)	2000-11-23	2008-11-04	Bavarian Nordic A/S	Modified Vaccinia Ankara virus variant and cultivation method
US6506576B2 (en)	2001-03-14	2003-01-14	Board Of Trustees Of The University Of Arkansas	Serum-and steroid-free culture media for cerebellar granule neurons
ES2305514T5 (es)	2002-09-05	2019-06-14	Bavarian Nordic As	Método para la amplificación de un poxvirus en condiciones exentas de suero
WO2007103447A2 (en) *	2006-03-06	2007-09-13	Humagene, Inc.	A method for the preparation of recombinant human thrombin
US8415094B2 (en) *	2007-12-21	2013-04-09	Jaffar Ali bin M. Abdullah	Protein-free gamete and embryo handling and culture media products
CN103898123B (zh) *	2012-12-28	2019-03-15	北京韩美药品有限公司	重组人IFN-β-1a及其生产和纯化方法
AU2014225272B2 (en)	2013-03-08	2015-10-22	Neuclone Biologics Pty Ltd	A cell expression system
AU2014225273A1 (en) *	2013-03-08	2015-09-24	Neuclone Biologics Pty Ltd	Cell culture media composition and methods of producing thereof
CN103484426B (zh) *	2013-10-15	2014-11-26	齐鲁制药有限公司	一种无动物源的低蛋白培养基
US9534026B2 (en)	2013-10-31	2017-01-03	China National Research Institute Of Food & Fermentation Industries	Corn active peptide additive for cell culture medium
CN104593318B (zh) *	2013-10-31	2018-05-04	中国食品发酵工业研究院	一种用于细胞培养基的玉米活性肽添加剂
JP7521738B2 (ja) *	2020-05-18	2024-07-24	キヤノン株式会社	目的細胞の生産方法、目的細胞による生産物の生産方法、および無血清培地

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AU621972B2 (en) *	1988-12-14	1992-03-26	United States of America, as represented by the Secretary, U.S. Department of Commerce, The	Cell culture medium for human liver epithelial cell line
CA2010424A1 (en) *	1989-02-27	1990-08-27	Walter F. Prouty	Tissue culture method
GB9022545D0 (en) *	1990-10-17	1990-11-28	Wellcome Found	Culture medium
US5256766A (en) *	1991-02-19	1993-10-26	The Regents Of The University Of California	Recombinant thrombin receptor and related pharmaceuticals

1992
- 1992-08-24 IL IL10292992A patent/IL102929A/en not_active IP Right Cessation
1993
- 1993-08-23 CA CA 2104643 patent/CA2104643C/en not_active Expired - Lifetime
- 1993-08-23 JP JP20805393A patent/JP4124493B2/ja not_active Expired - Lifetime
- 1993-08-24 PT PT93113502T patent/PT584788E/pt unknown
- 1993-08-24 DK DK93113502T patent/DK0584788T3/da active
- 1993-08-24 AT AT93113502T patent/ATE226632T1/de active
- 1993-08-24 AT AT00117026T patent/ATE348147T1/de active
- 1993-08-24 US US08/111,428 patent/US5641647A/en not_active Expired - Lifetime
- 1993-08-24 ES ES00117026T patent/ES2274756T3/es not_active Expired - Lifetime
- 1993-08-24 DE DE69332430T patent/DE69332430T2/de not_active Expired - Lifetime
- 1993-08-24 AU AU44871/93A patent/AU670957B2/en not_active Expired
- 1993-08-24 ZA ZA936192A patent/ZA936192B/xx unknown
- 1993-08-24 DE DE1993634097 patent/DE69334097T2/de not_active Expired - Lifetime
- 1993-08-24 EP EP19930113502 patent/EP0584788B1/de not_active Expired - Lifetime
- 1993-08-24 EP EP20000117026 patent/EP1045023B1/de not_active Expired - Lifetime
- 1993-08-24 PT PT00117026T patent/PT1045023E/pt unknown
- 1993-08-24 ES ES93113502T patent/ES2185618T3/es not_active Expired - Lifetime
- 1993-08-24 DK DK00117026T patent/DK1045023T3/da active
2007
- 2007-02-09 CY CY0700004A patent/CY2572B1/xx unknown

Also Published As

Publication number	Publication date
JP4124493B2 (ja)	2008-07-23
ATE348147T1 (de)	2007-01-15
DE69334097T2 (de)	2007-07-12
CA2104643A1 (en)	1994-02-25
EP0584788A3 (de)	1995-01-18
DK0584788T3 (da)	2003-02-24
JPH06153931A (ja)	1994-06-03
CY2572B1 (en)	2008-07-02
DE69332430T2 (de)	2003-07-17
PT584788E (pt)	2003-02-28
ZA936192B (en)	1994-03-22
AU4487193A (en)	1994-03-03
EP0584788A2 (de)	1994-03-02
ES2274756T3 (es)	2007-06-01
DE69334097D1 (de)	2007-01-25
DK1045023T3 (da)	2007-03-12
ATE226632T1 (de)	2002-11-15
EP1045023A1 (de)	2000-10-18
AU670957B2 (en)	1996-08-08
EP0584788B1 (de)	2002-10-23
EP1045023B1 (de)	2006-12-13
ES2185618T3 (es)	2003-05-01
US5641647A (en)	1997-06-24
DE69332430D1 (de)	2002-11-28
PT1045023E (pt)	2007-02-28
IL102929A0 (en)	1993-01-31
CA2104643C (en)	2009-07-21

Legal Events

Date	Code	Title
1997-04-15	FF	Patent granted
1997-07-13	KB	Patent renewed
1998-12-27	KB	Patent renewed
2002-09-12	KB	Patent renewed
2006-10-04	KB	Patent renewed
2010-11-30	KB	Patent renewed
2013-04-30	EXP	Patent expired

Publication	Publication Date	Title
EP1045023B1 (de)	2006-12-13	Serumfreies Medium
US6667034B2 (en)	2003-12-23	Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture, methods for assaying the effect of substances on lineage-specific cell production, and cell compositions produced by these cultures
AU780791B2 (en)	2005-04-14	Medium for the protein-free and serum-free cultivation of cells
KR100496356B1 (ko)	2005-11-25	포유동물세포배양으로생산되는단백질의시알릴화조절방법
EP0422186B1 (de)	1998-12-09	Verwendung von oncostatin m zur suppression von mhc antigenen
EP0412149B1 (de)	1995-11-08	Verwendung von il-7 bei arzneimitteln zur steigerung der plättchenherstellung
Migliaccio et al.	1988	Human embryonic hemopoiesis: control mechanisms underlying progenitor differentiation in vitro
KR20020013481A (ko)	2002-02-20	인자 ⅷ을 위한 발현 시스템
US20040170604A1 (en)	2004-09-02	IL-6 receptor IL-6 direct fusion protein
CA2342859A1 (en)	2000-03-16	Production of human erythropoietin
Kadouri et al.	1992	Dynamic changes in cytokine secretion by stromal cells during prolonged maintenance under protein‐free conditions
Hosoi et al.	1991	Optimization of cell culture conditions for production of biologically active proteins
EP1094081B1 (de)	2005-09-21	Fusionsprotein mit direkter verknüpfung des il-6-rezeptors mit il-6
JP2751325B2 (ja)	1998-05-18	蛋白質の産生方法
Laouar et al.	1994	Protease‐catalyzed conversion of insulin‐like growth factor‐1 and interleukin‐6 into high‐molecular‐mass species through the sequential action of hematopoietic surface‐associated cathepsin G and γ‐glutamyl transpeptidase‐related activities
EP1318198B1 (de)	2006-03-22	Verfahren zur Herstellung eines rekombinanten Polypeptids unter Hinzufügung eines Chymotrypsinhemmstoffes zum Zellkulturmedium
WO1994018310A1 (en)	1994-08-18	Growth enhancing media supplement for the culture of mammalian cells
Okaloe-Kado et al.	2008	Protein factors that regulate the growth and differentiation of mouse myeloid leukaemia cells