IL103065A - Isolated protein which inhibits collagen induced platelet aggregation, processes for the preparation thereof and a pharmaceutical composition containing the same - Google Patents

Isolated protein which inhibits collagen induced platelet aggregation, processes for the preparation thereof and a pharmaceutical composition containing the same

Info

Publication number
IL103065A
IL103065A IL10306592A IL10306592A IL103065A IL 103065 A IL103065 A IL 103065A IL 10306592 A IL10306592 A IL 10306592A IL 10306592 A IL10306592 A IL 10306592A IL 103065 A IL103065 A IL 103065A
Authority
IL
Israel
Prior art keywords
protein
inhibitor
collagen
dna
sequence
Prior art date
Application number
IL10306592A
Other languages
English (en)
Other versions
IL103065A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to IL11949192A priority Critical patent/IL119491A/xx
Publication of IL103065A0 publication Critical patent/IL103065A0/xx
Priority to IL11949196A priority patent/IL119491A0/xx
Publication of IL103065A publication Critical patent/IL103065A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
IL10306592A 1991-09-05 1992-09-04 Isolated protein which inhibits collagen induced platelet aggregation, processes for the preparation thereof and a pharmaceutical composition containing the same IL103065A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL11949192A IL119491A (en) 1991-09-05 1992-09-04 cDNA or DNA encoding a protein which inhibits collagen-induced platelet aggregation
IL11949196A IL119491A0 (en) 1991-09-05 1996-10-25 cDNA or DNA which inhibits collagen-induced platelet aggregation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75621191A 1991-09-05 1991-09-05
US81488491A 1991-12-31 1991-12-31
US91438392A 1992-07-17 1992-07-17

Publications (2)

Publication Number Publication Date
IL103065A0 IL103065A0 (en) 1993-02-21
IL103065A true IL103065A (en) 2001-11-25

Family

ID=27419489

Family Applications (4)

Application Number Title Priority Date Filing Date
IL10306592A IL103065A (en) 1991-09-05 1992-09-04 Isolated protein which inhibits collagen induced platelet aggregation, processes for the preparation thereof and a pharmaceutical composition containing the same
IL11949192A IL119491A (en) 1991-09-05 1992-09-04 cDNA or DNA encoding a protein which inhibits collagen-induced platelet aggregation
IL11949296A IL119492A0 (en) 1991-09-05 1996-10-25 Proteins which inhibit collagen-induced platelet aggregation DNA and cDNA coding therefor processes for its production and pharmaceutical compositions containing the same
IL11949196A IL119491A0 (en) 1991-09-05 1996-10-25 cDNA or DNA which inhibits collagen-induced platelet aggregation

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL11949192A IL119491A (en) 1991-09-05 1992-09-04 cDNA or DNA encoding a protein which inhibits collagen-induced platelet aggregation
IL11949296A IL119492A0 (en) 1991-09-05 1996-10-25 Proteins which inhibit collagen-induced platelet aggregation DNA and cDNA coding therefor processes for its production and pharmaceutical compositions containing the same
IL11949196A IL119491A0 (en) 1991-09-05 1996-10-25 cDNA or DNA which inhibits collagen-induced platelet aggregation

Country Status (16)

Country Link
EP (1) EP0530937B1 (de)
JP (2) JPH07506959A (de)
KR (1) KR100232683B1 (de)
AT (1) ATE169674T1 (de)
AU (1) AU672584B2 (de)
CA (1) CA2117174A1 (de)
DE (1) DE69226580T2 (de)
DK (1) DK0530937T3 (de)
ES (1) ES2121817T3 (de)
FI (1) FI112801B (de)
HU (1) HU218830B (de)
IL (4) IL103065A (de)
NO (1) NO314848B1 (de)
NZ (1) NZ244246A (de)
RU (1) RU2128705C1 (de)
WO (1) WO1993005150A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2199719A1 (en) * 1994-09-12 1996-03-21 Christiane Noeske-Jungblut Process for manufacture of a modified collagen-induced platelet aggregation inhibitor pallidipin
GB2304048A (en) * 1995-08-12 1997-03-12 John William Carson Medicament containing saliva extract
RU2199985C2 (ru) * 2000-05-26 2003-03-10 Самойлов Александр Николаевич Способ лечения гифемы
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
RU2192857C1 (ru) * 2001-04-24 2002-11-20 Институт органической химии им. Н.Д. Зелинского РАН Ингибитор агрегации тромбоцитов, обладающий антиметастатическим действием
JP3837519B2 (ja) 2002-10-02 2006-10-25 国立大学法人三重大学 血小板凝集阻害活性を有するブラジルサシガメ由来のＴｉ−３蛋白質
JP3837518B2 (ja) 2002-10-02 2006-10-25 国立大学法人三重大学 血小板凝集阻害活性を有するブラジルサシガメ由来のＴｉ−４蛋白質
WO2004096267A1 (de) * 2003-05-02 2004-11-11 Paion Gmbh Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall
EP1625147B1 (de) * 2003-05-21 2008-01-23 Ares Trading S.A. Verfahren zur chromatographischen analyse einer proteinlösung
EP1760092A1 (de) * 2005-08-26 2007-03-07 Applied Research Systems ARS Holding N.V. System für Screening von Zellen mit hoher Expression von einem interessierenden Protein
EP1931733A4 (de) 2005-09-28 2009-11-25 Biovascular Inc Verfahren und zusammensetzungen zum blockieren von thrombozyten- und zelladhäsion, zellmigration und entzündung
JP5332178B2 (ja) * 2007-11-02 2013-11-06 東洋紡株式会社 多色ルシフェラーゼの検出方法
JP5747370B2 (ja) * 2009-03-31 2015-07-15 国立大学法人浜松医科大学 高病原性口腔細菌の高感度検出法
CN109125355B (zh) * 2018-08-03 2022-07-08 昆明医科大学第一附属医院 心脉隆抗血小板及抗血栓药理应用
CN112354571B (zh) * 2019-07-11 2022-02-11 北京理工大学 一种多维微流控电泳芯片及检测装置，检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040149B1 (de) * 1980-05-12 1984-05-09 Choay S.A. Oligopeptide mit spezifisch hemmenden Wirkungen gegen die durch den Kollagen induzierte Aggregatbildung, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5037808A (en) * 1988-07-20 1991-08-06 Monsanto Co. Indolyl platelet-aggregation inhibitors
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation

Also Published As

Publication number Publication date
AU2502292A (en) 1993-04-05
RU2128705C1 (ru) 1999-04-10
AU672584B2 (en) 1996-10-10
IL119491A0 (en) 1997-01-10
RU94045930A (ru) 1996-07-20
EP0530937B1 (de) 1998-08-12
DE69226580T2 (de) 1999-03-04
CA2117174A1 (en) 1993-03-18
WO1993005150A1 (en) 1993-03-18
HUT70271A (en) 1995-09-28
FI941052L (fi) 1994-03-04
NZ244246A (en) 1994-03-25
HU218830B (hu) 2000-12-28
DK0530937T3 (da) 1999-05-10
DE69226580D1 (de) 1998-09-17
ES2121817T3 (es) 1998-12-16
EP0530937A1 (de) 1993-03-10
FI112801B (fi) 2004-01-15
FI941052A0 (fi) 1994-03-04
KR100232683B1 (ko) 1999-12-01
ATE169674T1 (de) 1998-08-15
NO940771L (no) 1994-03-04
IL119491A (en) 2000-11-21
HU9400662D0 (en) 1994-06-28
IL119492A0 (en) 1997-01-10
NO940771D0 (no) 1994-03-04
JP2003313199A (ja) 2003-11-06
IL103065A0 (en) 1993-02-21
JPH07506959A (ja) 1995-08-03
NO314848B1 (no) 2003-06-02

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees