ES2121817T3 - Inhibidor de la agregacion plaquetaria inducida por el colageno. - Google Patents

Inhibidor de la agregacion plaquetaria inducida por el colageno.

Info

Publication number
ES2121817T3
ES2121817T3 ES92250245T ES92250245T ES2121817T3 ES 2121817 T3 ES2121817 T3 ES 2121817T3 ES 92250245 T ES92250245 T ES 92250245T ES 92250245 T ES92250245 T ES 92250245T ES 2121817 T3 ES2121817 T3 ES 2121817T3
Authority
ES
Spain
Prior art keywords
platelet aggregation
collagen
inhibitor
aggregation induced
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92250245T
Other languages
English (en)
Inventor
Christiane Noeske-Jungblut
Bernhard Haendler
Jorn Kratzschmar
Wolf-Dieter Schleuning
Alejandro Alagon
Lourival Possani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2121817T3 publication Critical patent/ES2121817T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Insects & Arthropods (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

EL INVENTO DESCRIBE UNA PROTEINA QUE INHIBE AGREGACION DE PLAQUETA INDUCIDA DE COLAGENO DERIVADA DE TRIATOMA PALLIDIPENNIS Y DERIVADOS CONSIGUIENTES. LA PROTEINA SE UTILIZA COMO UN MEDICAMENTO PARA INHIBICION DE AGREGACION DE PLAQUETA INDUCIDA DE COLAGENO O DE CANCER CON CELULAS TUMORALES METASTATICAS.
ES92250245T 1991-09-05 1992-09-04 Inhibidor de la agregacion plaquetaria inducida por el colageno. Expired - Lifetime ES2121817T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75621191A 1991-09-05 1991-09-05
US81488491A 1991-12-31 1991-12-31
US91438392A 1992-07-17 1992-07-17

Publications (1)

Publication Number Publication Date
ES2121817T3 true ES2121817T3 (es) 1998-12-16

Family

ID=27419489

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92250245T Expired - Lifetime ES2121817T3 (es) 1991-09-05 1992-09-04 Inhibidor de la agregacion plaquetaria inducida por el colageno.

Country Status (16)

Country Link
EP (1) EP0530937B1 (es)
JP (2) JPH07506959A (es)
KR (1) KR100232683B1 (es)
AT (1) ATE169674T1 (es)
AU (1) AU672584B2 (es)
CA (1) CA2117174A1 (es)
DE (1) DE69226580T2 (es)
DK (1) DK0530937T3 (es)
ES (1) ES2121817T3 (es)
FI (1) FI112801B (es)
HU (1) HU218830B (es)
IL (4) IL119491A (es)
NO (1) NO314848B1 (es)
NZ (1) NZ244246A (es)
RU (1) RU2128705C1 (es)
WO (1) WO1993005150A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222398B1 (hu) * 1994-09-12 2003-06-28 Schering Aktiengesellschaft Eljárás pallidipin, egy módosított, kollagénindukált vérlemezke-aggregációt gátló vegyület előállítására
GB2304048A (en) * 1995-08-12 1997-03-12 John William Carson Medicament containing saliva extract
RU2199985C2 (ru) * 2000-05-26 2003-03-10 Самойлов Александр Николаевич Способ лечения гифемы
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
RU2192857C1 (ru) * 2001-04-24 2002-11-20 Институт органической химии им. Н.Д. Зелинского РАН Ингибитор агрегации тромбоцитов, обладающий антиметастатическим действием
JP3837519B2 (ja) 2002-10-02 2006-10-25 国立大学法人三重大学 血小板凝集阻害活性を有するブラジルサシガメ由来のＴｉ−３蛋白質
JP3837518B2 (ja) 2002-10-02 2006-10-25 国立大学法人三重大学 血小板凝集阻害活性を有するブラジルサシガメ由来のＴｉ−４蛋白質
AU2003227721A1 (en) * 2003-05-02 2004-11-23 Paion Gmbh Intravenous injection of non-neurotoxic plasminogen activators for the treatment of stroke
WO2004104025A1 (en) * 2003-05-21 2004-12-02 Ares Trading S.A. Method of chromatographic analysis of a protein solution
EP1760092A1 (en) * 2005-08-26 2007-03-07 Applied Research Systems ARS Holding N.V. System for screening cells for high expression of a protein of interest
CA2623565A1 (en) 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
JP5332178B2 (ja) * 2007-11-02 2013-11-06 東洋紡株式会社 多色ルシフェラーゼの検出方法
JP5747370B2 (ja) * 2009-03-31 2015-07-15 国立大学法人浜松医科大学 高病原性口腔細菌の高感度検出法
CN109125355B (zh) * 2018-08-03 2022-07-08 昆明医科大学第一附属医院 心脉隆抗血小板及抗血栓药理应用
CN112354572B (zh) * 2019-07-11 2022-02-11 北京理工大学 一种多维微流控电泳芯片及检测装置，检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3163469D1 (en) * 1980-05-12 1984-06-14 Choay Sa Oligopeptides with specific inhibiting properties of collagen induced aggregation, process for preparing the same and pharmaceutical compositions containing them
US5037808A (en) * 1988-07-20 1991-08-06 Monsanto Co. Indolyl platelet-aggregation inhibitors
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation

Also Published As

Publication number Publication date
FI941052A0 (fi) 1994-03-04
JP2003313199A (ja) 2003-11-06
EP0530937A1 (en) 1993-03-10
JPH07506959A (ja) 1995-08-03
NZ244246A (en) 1994-03-25
RU2128705C1 (ru) 1999-04-10
NO940771L (no) 1994-03-04
DE69226580T2 (de) 1999-03-04
IL119492A0 (en) 1997-01-10
IL103065A (en) 2001-11-25
IL119491A (en) 2000-11-21
ATE169674T1 (de) 1998-08-15
DE69226580D1 (de) 1998-09-17
HUT70271A (en) 1995-09-28
DK0530937T3 (da) 1999-05-10
RU94045930A (ru) 1996-07-20
NO314848B1 (no) 2003-06-02
IL103065A0 (en) 1993-02-21
EP0530937B1 (en) 1998-08-12
HU218830B (hu) 2000-12-28
KR100232683B1 (ko) 1999-12-01
WO1993005150A1 (en) 1993-03-18
IL119491A0 (en) 1997-01-10
CA2117174A1 (en) 1993-03-18
NO940771D0 (no) 1994-03-04
AU672584B2 (en) 1996-10-10
AU2502292A (en) 1993-04-05
HU9400662D0 (en) 1994-06-28
FI941052L (fi) 1994-03-04
FI112801B (fi) 2004-01-15

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