IL105874A - Genomic dna sequences encoding human bssl/cel - Google Patents

Genomic dna sequences encoding human bssl/cel

Info

Publication number
IL105874A
IL105874A IL10587493A IL10587493A IL105874A IL 105874 A IL105874 A IL 105874A IL 10587493 A IL10587493 A IL 10587493A IL 10587493 A IL10587493 A IL 10587493A IL 105874 A IL105874 A IL 105874A
Authority
IL
Israel
Prior art keywords
cel
human
bssl
gene
vector
Prior art date
Application number
IL10587493A
Other languages
English (en)
Other versions
IL105874A0 (en
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9201809A external-priority patent/SE9201809D0/xx
Priority claimed from SE9201826A external-priority patent/SE9201826D0/xx
Priority claimed from SE9202088A external-priority patent/SE9202088D0/xx
Priority claimed from SE9300902A external-priority patent/SE9300902D0/xx
Application filed by Astra Ab filed Critical Astra Ab
Publication of IL105874A0 publication Critical patent/IL105874A0/xx
Publication of IL105874A publication Critical patent/IL105874A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Animal Husbandry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
IL10587493A 1992-06-11 1993-06-01 Genomic dna sequences encoding human bssl/cel IL105874A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9201809A SE9201809D0 (sv) 1992-06-11 1992-06-11 New dna sequences
SE9201826A SE9201826D0 (sv) 1992-06-12 1992-06-12 New dna sequences ii
SE9202088A SE9202088D0 (sv) 1992-07-03 1992-07-03 New dna sequences iii
SE9300902A SE9300902D0 (sv) 1993-03-19 1993-03-19 New dna sequences iv

Publications (2)

Publication Number Publication Date
IL105874A0 IL105874A0 (en) 1993-10-20
IL105874A true IL105874A (en) 1998-12-27

Family

ID=27484751

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10587493A IL105874A (en) 1992-06-11 1993-06-01 Genomic dna sequences encoding human bssl/cel

Country Status (31)

Country Link
US (2) US5616483A (de)
EP (1) EP0651793B1 (de)
JP (1) JP4231105B2 (de)
KR (1) KR100357670B1 (de)
CN (1) CN1071791C (de)
AP (1) AP411A (de)
AT (1) ATE447012T1 (de)
AU (1) AU670598B2 (de)
CA (1) CA2137815C (de)
CZ (1) CZ288677B6 (de)
DE (1) DE69334298D1 (de)
DK (1) DK0651793T3 (de)
ES (1) ES2335626T3 (de)
FI (1) FI945793A7 (de)
HR (1) HRP930935A2 (de)
HU (1) HU220338B (de)
IL (1) IL105874A (de)
IS (1) IS4029A (de)
MA (1) MA22905A1 (de)
MX (1) MX9303439A (de)
NO (1) NO944715L (de)
NZ (1) NZ253391A (de)
PH (1) PH31680A (de)
PT (1) PT651793E (de)
RU (1) RU2128708C1 (de)
SG (1) SG52580A1 (de)
SI (1) SI9300319A (de)
SK (1) SK286993B6 (de)
TN (1) TNSN93067A1 (de)
UA (1) UA41322C2 (de)
WO (1) WO1993025669A1 (de)

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CA2184688A1 (en) * 1994-03-09 1995-09-14 Pedro Antonio Prieto Transgenic animals producing oligosaccharides and glycoconjugates
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
AU750891B2 (en) 1996-12-06 2002-08-01 Aventis Pharmaceuticals Inc. Polypeptides encoded by a human lipase-like gene, compositions and methods
US7008776B1 (en) * 1996-12-06 2006-03-07 Aventis Pharmaceuticals Inc. Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
FR2763958A1 (fr) * 1997-05-29 1998-12-04 Transgene Sa Produit de combinaison associant un acide nucleique a une substance desorganisant la matrice extracellulaire pour la therapie genique
US20020088019A1 (en) * 1997-09-02 2002-07-04 Oron Yacoby-Zeevi Methods of and pharmaceutical compositions for improving implantation of embryos
US6699672B1 (en) 1997-09-02 2004-03-02 Insight Biopharmaceuticals Ltd. Heparanase specific molecular probes and their use research and medical applications
US6177545B1 (en) * 1997-09-02 2001-01-23 Insight Strategy & Marketing Ltd. Heparanase specific molecular probes and their use in research and medical applications
US20040213789A1 (en) * 1997-09-02 2004-10-28 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies
US20010006630A1 (en) * 1997-09-02 2001-07-05 Oron Yacoby-Zeevi Introducing a biological material into a patient
SE9801424D0 (sv) 1998-04-22 1998-04-22 Astra Ab Expression methods
US20030217375A1 (en) * 1998-08-31 2003-11-20 Eyal Zcharia Transgenic animals expressing heparanase and uses thereof
EP1157118A4 (de) * 1999-03-01 2002-07-17 Insight Strategy & Marketing POLYNUKLEOTID, DAS FüR EIN POLYPEPTID MIT HEPARANASE-AKTIVäT KODIERT, UND DESSEN EXPRESSION IN GENETISCH VERäNDERTEN ZELLEN
EP1175503A1 (de) * 1999-04-09 2002-01-30 Human Genome Sciences, Inc. 49 humane sekretierte proteine
AU5032600A (en) * 1999-05-19 2001-12-03 Barnes-Jewish Hospital Enhanced triglyceride digestion in a deficiency of bile salts
WO2002010217A2 (en) 2000-08-02 2002-02-07 The Johns Hopkins University Endothelial cell expression patterns
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US20100268658A1 (en) * 2001-05-14 2010-10-21 Prolacta Bioscience Method for collecting, testing and distributing milk
US20020182243A1 (en) * 2001-05-14 2002-12-05 Medo Elena Maria Method of producing nutritional products from human milk tissue and compositions thereof
US6671189B2 (en) * 2001-11-09 2003-12-30 Minebea Co., Ltd. Power converter having primary and secondary side switches
US20030213007A1 (en) * 2002-03-27 2003-11-13 Slattery Charles Wilbur Human milk produced by human mammary tissue implanted in non-human host animals and uses thereof
US20060269552A1 (en) * 2003-06-09 2006-11-30 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monclonal antibody and other anti-heparanase antibodies
WO2007035870A2 (en) 2005-09-20 2007-03-29 Prolacta Bioscience, Inc. A method for testing milk
WO2007089133A1 (en) * 2006-02-03 2007-08-09 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing interactions between dc-sign and dc-sign ligands
WO2008067486A2 (en) * 2006-11-29 2008-06-05 Prolacta Bioscience, Inc. Human milk compositions and methods of making and using same
ES2396571T3 (es) 2006-12-08 2013-02-22 Prolacta Bioscience, Inc. Composiciones de lípidos humanos y procedimientos de preparación y utilización de los mismos
PT2079445E (pt) 2007-02-20 2016-02-29 Allergan Pharmaceuticals Internat Ltd Composições de enzimas digestivas estáveis
WO2009109856A2 (en) 2008-03-07 2009-09-11 Axcan Pharma Inc. Method for detecting infectious parvovirus in pharmaceutical preparations
EP2370084B1 (de) 2008-12-02 2014-10-22 Prolacta Bioscience, Inc. Muttermilchpermeatzusammensetzungen sowie verfahren zu ihrer herstellung und verwendung
EA029101B1 (ru) 2010-10-01 2018-02-28 Апталис Фарма Лимитид Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием
JP5850940B2 (ja) * 2010-10-21 2016-02-03 スウェディッシュ オーファン バイオビトラム パブリーク アクチエボラグ ヒト乳児の発育速度を増大させる方法
AU2010362575A1 (en) * 2010-10-21 2013-04-11 Swedish Orphan Biovitrum Ab (Publ) Method to increase the absorption of unsaturated fatty acids by human infants
CN103987265B (zh) 2011-08-03 2017-05-24 普罗莱克塔生物科学公司 减少细菌污染的人乳微滤
CA2843556A1 (en) 2011-08-08 2013-02-14 Aptalis Pharma Ltd. Method for dissolution testing of solid compositions containing digestive enzymes
CN103088000A (zh) * 2012-03-23 2013-05-08 北京济福霖生物技术有限公司 在哺乳动物乳腺中过表达胆盐激活脂酶的方法
KR20150037968A (ko) * 2012-07-12 2015-04-08 프로큐알 테라퓨틱스 엔.브이. 살아있는 세포 내에 존재하는 목적 rna 분자의 서열을 변화시키기 위한 올리고뉴클레오타이드
ES2843254T3 (es) 2013-03-13 2021-07-16 Prolacta Bioscience Inc Productos de leche humana rica en grasas
EP3639846B1 (de) 2013-08-09 2022-09-28 Allergan Pharmaceuticals International Limited Verdauungsenzymzusammensetzung zur enteralen verabreichung
EP3157568A1 (de) 2014-06-19 2017-04-26 Aptalis Pharma Limited Verfahren zur entfernung von viralen verunreinigungen aus pankreatischen extrakten
IL260327B2 (en) 2015-12-30 2023-10-01 Prolacta Bioscience Inc Human milk products used before and after active treatment
AU2020354581A1 (en) 2019-09-24 2022-03-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases

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US3256150A (en) * 1964-04-20 1966-06-14 Dairyland Food Lab Method for treating malabsorption syndrome
GB1509866A (en) * 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions
US4873316A (en) * 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US4944944A (en) * 1987-11-19 1990-07-31 Oklahoma Medical Research Foundation Dietary compositions and methods using bile salt-activated lipase
US5200183A (en) * 1987-11-19 1993-04-06 Oklahoma Medical Research Foundation Recombinant bile salt activated lipases
SU1573026A1 (ru) * 1988-07-22 1990-06-23 Институт Биохимии И Физиологии Микроорганизмов Ан Ссср Рекомбинантна плазмидна ДНК pBG М3, определ юща синтез эндонуклеазы рестрикции С @ BI
US5173408A (en) * 1989-11-13 1992-12-22 Lange Louis George Iii Mammalian pancreatic cholesterol esterase
WO1991015534A1 (en) * 1990-03-30 1991-10-17 Allied-Signal Inc. Electrically conductive poly(aromatic vinylenes) and poly(heteroaromatic vinylenes)
SE9001985D0 (sv) * 1990-06-01 1990-06-01 Astra Ab New chemical products

Also Published As

Publication number Publication date
AU670598B2 (en) 1996-07-25
AP411A (en) 1995-09-28
IS4029A (is) 1993-12-12
HUT71789A (en) 1996-02-28
DE69334298D1 (de) 2009-12-10
PT651793E (pt) 2010-01-20
AU4366793A (en) 1994-01-04
KR100357670B1 (ko) 2003-04-11
SG52580A1 (en) 1998-09-28
RU94046360A (ru) 1997-06-10
NO944715D0 (no) 1994-12-07
CA2137815C (en) 2010-11-09
US5616483A (en) 1997-04-01
FI945793L (fi) 1995-02-09
FI945793A0 (fi) 1994-12-09
NZ253391A (en) 1996-01-26
HU9403536D0 (en) 1995-02-28
CZ288677B6 (cs) 2001-08-15
IL105874A0 (en) 1993-10-20
JP4231105B2 (ja) 2009-02-25
CN1086262A (zh) 1994-05-04
SI9300319A (en) 1994-03-31
ES2335626T3 (es) 2010-03-30
SK148694A3 (en) 1995-08-09
RU2128708C1 (ru) 1999-04-10
US5716817A (en) 1998-02-10
MX9303439A (es) 1994-04-29
EP0651793B1 (de) 2009-10-28
CZ309194A3 (en) 1995-07-12
WO1993025669A1 (en) 1993-12-23
MA22905A1 (fr) 1993-12-31
CN1071791C (zh) 2001-09-26
CA2137815A1 (en) 1993-12-23
HRP930935A2 (en) 1994-12-31
FI945793A7 (fi) 1995-02-09
PH31680A (en) 1999-01-18
EP0651793A1 (de) 1995-05-10
JPH07507687A (ja) 1995-08-31
UA41322C2 (uk) 2001-09-17
TNSN93067A1 (fr) 1994-03-17
DK0651793T3 (da) 2010-03-15
NO944715L (no) 1995-02-07
AP9300538A0 (en) 1993-07-31
SK286993B6 (sk) 2009-09-07
HU220338B (hu) 2001-12-28
ATE447012T1 (de) 2009-11-15

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