IS4029A - DNA-raðir notaðar við framleiðslu á endurröðuðum mennskum gallsaltahvötuðum lípasa - Google Patents

DNA-raðir notaðar við framleiðslu á endurröðuðum mennskum gallsaltahvötuðum lípasa

Info

Publication number
IS4029A
IS4029A IS4029A IS4029A IS4029A IS 4029 A IS4029 A IS 4029A IS 4029 A IS4029 A IS 4029A IS 4029 A IS4029 A IS 4029A IS 4029 A IS4029 A IS 4029A
Authority
IS
Iceland
Prior art keywords
production
dna sequences
recombinant human
sequences used
bile salt
Prior art date
Application number
IS4029A
Other languages
English (en)
Inventor
Gunnar Bjursell Karl
Nils Ivar Carlsson Peter
Sven Magnus Enerbäck Curt
Lennart Hansson Stig
Fredrik Pontus Lidberg Ulf
Annika Nilsson Jeanette
Birger Fredrik Törnell Jan
Original Assignee
Ab Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9201809A external-priority patent/SE9201809D0/xx
Priority claimed from SE9201826A external-priority patent/SE9201826D0/xx
Priority claimed from SE9202088A external-priority patent/SE9202088D0/xx
Priority claimed from SE9300902A external-priority patent/SE9300902D0/xx
Application filed by Ab Astra filed Critical Ab Astra
Publication of IS4029A publication Critical patent/IS4029A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278Knock-in vertebrates, e.g. humanised vertebrates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/20Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/15Humanized animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/01Animal expressing industrially exogenous proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
IS4029A 1992-06-11 1993-06-07 DNA-raðir notaðar við framleiðslu á endurröðuðum mennskum gallsaltahvötuðum lípasa IS4029A (is)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9201809A SE9201809D0 (sv) 1992-06-11 1992-06-11 New dna sequences
SE9201826A SE9201826D0 (sv) 1992-06-12 1992-06-12 New dna sequences ii
SE9202088A SE9202088D0 (sv) 1992-07-03 1992-07-03 New dna sequences iii
SE9300902A SE9300902D0 (sv) 1993-03-19 1993-03-19 New dna sequences iv

Publications (1)

Publication Number Publication Date
IS4029A true IS4029A (is) 1993-12-12

Family

ID=27484751

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4029A IS4029A (is) 1992-06-11 1993-06-07 DNA-raðir notaðar við framleiðslu á endurröðuðum mennskum gallsaltahvötuðum lípasa

Country Status (31)

Country Link
US (2) US5616483A (is)
EP (1) EP0651793B1 (is)
JP (1) JP4231105B2 (is)
KR (1) KR100357670B1 (is)
CN (1) CN1071791C (is)
AP (1) AP411A (is)
AT (1) ATE447012T1 (is)
AU (1) AU670598B2 (is)
CA (1) CA2137815C (is)
CZ (1) CZ288677B6 (is)
DE (1) DE69334298D1 (is)
DK (1) DK0651793T3 (is)
ES (1) ES2335626T3 (is)
FI (1) FI945793A7 (is)
HR (1) HRP930935A2 (is)
HU (1) HU220338B (is)
IL (1) IL105874A (is)
IS (1) IS4029A (is)
MA (1) MA22905A1 (is)
MX (1) MX9303439A (is)
NO (1) NO944715L (is)
NZ (1) NZ253391A (is)
PH (1) PH31680A (is)
PT (1) PT651793E (is)
RU (1) RU2128708C1 (is)
SG (1) SG52580A1 (is)
SI (1) SI9300319A (is)
SK (1) SK286993B6 (is)
TN (1) TNSN93067A1 (is)
UA (1) UA41322C2 (is)
WO (1) WO1993025669A1 (is)

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US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
ATE291080T1 (de) 1996-12-06 2005-04-15 Aventis Pharma Inc Von humanem lipase-ähnlichem gen kodierte polypeptide, sowie zusammensetzungen und methoden
US7008776B1 (en) * 1996-12-06 2006-03-07 Aventis Pharmaceuticals Inc. Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
FR2763958A1 (fr) * 1997-05-29 1998-12-04 Transgene Sa Produit de combinaison associant un acide nucleique a une substance desorganisant la matrice extracellulaire pour la therapie genique
US20010006630A1 (en) * 1997-09-02 2001-07-05 Oron Yacoby-Zeevi Introducing a biological material into a patient
US20040213789A1 (en) * 1997-09-02 2004-10-28 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies
US20020088019A1 (en) * 1997-09-02 2002-07-04 Oron Yacoby-Zeevi Methods of and pharmaceutical compositions for improving implantation of embryos
US6177545B1 (en) * 1997-09-02 2001-01-23 Insight Strategy & Marketing Ltd. Heparanase specific molecular probes and their use in research and medical applications
US6699672B1 (en) 1997-09-02 2004-03-02 Insight Biopharmaceuticals Ltd. Heparanase specific molecular probes and their use research and medical applications
SE9801424D0 (sv) * 1998-04-22 1998-04-22 Astra Ab Expression methods
US20030217375A1 (en) * 1998-08-31 2003-11-20 Eyal Zcharia Transgenic animals expressing heparanase and uses thereof
EP1157118A4 (en) * 1999-03-01 2002-07-17 Insight Strategy & Marketing POLYNUCLEOTID ENCODING A POLYPEPTIDE WITH HEPARANASE ACTIVITY AND ITS EXPRESSION IN GENETICALLY MODIFIED CELLS
AU4074400A (en) * 1999-04-09 2000-11-14 Human Genome Sciences, Inc. 49 human secreted proteins
AU5032600A (en) * 1999-05-19 2001-12-03 Barnes-Jewish Hospital Enhanced triglyceride digestion in a deficiency of bile salts
US7402660B2 (en) 2000-08-02 2008-07-22 The Johns Hopkins University Endothelial cell expression patterns
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US20020182243A1 (en) * 2001-05-14 2002-12-05 Medo Elena Maria Method of producing nutritional products from human milk tissue and compositions thereof
US20100268658A1 (en) * 2001-05-14 2010-10-21 Prolacta Bioscience Method for collecting, testing and distributing milk
US6671189B2 (en) * 2001-11-09 2003-12-30 Minebea Co., Ltd. Power converter having primary and secondary side switches
US20030213007A1 (en) * 2002-03-27 2003-11-13 Slattery Charles Wilbur Human milk produced by human mammary tissue implanted in non-human host animals and uses thereof
US20060269552A1 (en) * 2003-06-09 2006-11-30 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monclonal antibody and other anti-heparanase antibodies
WO2007035870A2 (en) * 2005-09-20 2007-03-29 Prolacta Bioscience, Inc. A method for testing milk
WO2007089133A1 (en) * 2006-02-03 2007-08-09 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing interactions between dc-sign and dc-sign ligands
EP3485742B1 (en) * 2006-11-29 2021-09-01 Prolacta Bioscience, Inc. Human milk compositions and methods of making and using same
WO2008073888A2 (en) 2006-12-08 2008-06-19 Prolacta Bioscience, Inc. Compositions of human lipids and methods of making and using same
DK2079445T3 (en) 2007-02-20 2016-02-15 Allergan Pharmaceuticals Internat Ltd Stable digestive compositions
WO2009109856A2 (en) 2008-03-07 2009-09-11 Axcan Pharma Inc. Method for detecting infectious parvovirus in pharmaceutical preparations
US8927027B2 (en) 2008-12-02 2015-01-06 Prolacta Bioscience Human milk permeate compositions and methods of making and using same
KR20140019292A (ko) 2010-10-01 2014-02-14 아프탈리스 파르마 리미티드 장용 코팅된 저 강도 췌장 리파제 제제
JP5800907B2 (ja) 2010-10-21 2015-10-28 スウェディッシュ オーファン バイオビトラム パブリーク アクチエボラグ ヒト乳児による不飽和脂肪酸の吸収を増大させる方法
WO2012052060A1 (en) * 2010-10-21 2012-04-26 Swedish Orphan Biovitrum Ab (Publ) Method to increase the growth velocity of human infants
ES2655019T3 (es) 2011-08-03 2018-02-16 Prolacta Bioscience, Inc. Microfiltración de leche humana para reducir la contaminación bacteriana
ES2558756T3 (es) 2011-08-08 2016-02-08 Aptalis Pharma Limited Método para la prueba de disolución de composiciones sólidas que contienen enzimas digestivas
CN103088000A (zh) * 2012-03-23 2013-05-08 北京济福霖生物技术有限公司 在哺乳动物乳腺中过表达胆盐激活脂酶的方法
US9605255B2 (en) * 2012-07-12 2017-03-28 Proqr Therapeutics Ii B.V. Oligonucleotides for making a change in the sequence of a target RNA molecule present in a living cell
BR112015022059B1 (pt) 2013-03-13 2021-06-08 Prolacta Bioscience, Inc composições de nata de leite humano pasteurizada com alto teor de gordura e método para fabricar uma composição de nata de leite humano pasteurizada com alto teor de gordura
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RU2679832C2 (ru) 2013-08-09 2019-02-13 Аллерган Фармасьютикалз Интернэйшнл Лимитед Композиция пищеварительных ферментов, подходящая для энтерального введения
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Also Published As

Publication number Publication date
JPH07507687A (ja) 1995-08-31
IL105874A0 (en) 1993-10-20
ATE447012T1 (de) 2009-11-15
HU220338B (hu) 2001-12-28
EP0651793A1 (en) 1995-05-10
US5616483A (en) 1997-04-01
HU9403536D0 (en) 1995-02-28
HUT71789A (en) 1996-02-28
RU94046360A (ru) 1997-06-10
ES2335626T3 (es) 2010-03-30
FI945793L (fi) 1995-02-09
FI945793A7 (fi) 1995-02-09
CZ309194A3 (en) 1995-07-12
CA2137815A1 (en) 1993-12-23
WO1993025669A1 (en) 1993-12-23
AU4366793A (en) 1994-01-04
SG52580A1 (en) 1998-09-28
SI9300319A (en) 1994-03-31
AP9300538A0 (en) 1993-07-31
DK0651793T3 (da) 2010-03-15
TNSN93067A1 (fr) 1994-03-17
EP0651793B1 (en) 2009-10-28
SK148694A3 (en) 1995-08-09
KR100357670B1 (ko) 2003-04-11
IL105874A (en) 1998-12-27
FI945793A0 (fi) 1994-12-09
UA41322C2 (uk) 2001-09-17
CN1086262A (zh) 1994-05-04
NZ253391A (en) 1996-01-26
CA2137815C (en) 2010-11-09
NO944715D0 (no) 1994-12-07
CN1071791C (zh) 2001-09-26
HRP930935A2 (en) 1994-12-31
CZ288677B6 (cs) 2001-08-15
JP4231105B2 (ja) 2009-02-25
US5716817A (en) 1998-02-10
MX9303439A (es) 1994-04-29
PT651793E (pt) 2010-01-20
NO944715L (no) 1995-02-07
SK286993B6 (sk) 2009-09-07
RU2128708C1 (ru) 1999-04-10
AP411A (en) 1995-09-28
DE69334298D1 (de) 2009-12-10
AU670598B2 (en) 1996-07-25
MA22905A1 (fr) 1993-12-31
PH31680A (en) 1999-01-18

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