IL109645A - Synthetic aglucodalbaheptide antibiotics their preparation and pharmaceutical compositions comprising them - Google Patents

Synthetic aglucodalbaheptide antibiotics their preparation and pharmaceutical compositions comprising them

Info

Publication number: IL109645A
Authority: IL; Israel
Prior art keywords: pct; synthetic; preparation; pharmaceutical compositions; group
Prior art date: 1993-05-19

Application number

IL10964594A

Other languages

English (en)

Other versions

IL109645A0 (en

Inventor

Adriano Malabarba

Romeo Ciabatti

Original Assignee

Biosearch Italia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-19

Filing date

1994-05-12

Publication date

2000-06-01

1994-05-12 Application filed by Biosearch Italia Spa filed Critical Biosearch Italia Spa

1994-08-26 Publication of IL109645A0 publication Critical patent/IL109645A0/xx

2000-06-01 Publication of IL109645A publication Critical patent/IL109645A/xx

Links

239000003242 anti bacterial agent Substances 0.000 title abstract 2
229940088710 antibiotic agent Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compounds Of Unknown Constitution (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

IL10964594A 1993-05-19 1994-05-12 Synthetic aglucodalbaheptide antibiotics their preparation and pharmaceutical compositions comprising them IL109645A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP93108139		1993-05-19

Publications (2)

Publication Number	Publication Date
IL109645A0 IL109645A0 (en)	1994-08-26
IL109645A true IL109645A (en)	2000-06-01

Family

ID=8212919

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL10964594A IL109645A (en)	1993-05-19	1994-05-12	Synthetic aglucodalbaheptide antibiotics their preparation and pharmaceutical compositions comprising them

Country Status (17)

Country	Link
US (1)	US5674840A (de)
EP (1)	EP0698041B1 (de)
JP (1)	JP3503066B2 (de)
KR (1)	KR100298136B1 (de)
AT (1)	ATE159533T1 (de)
AU (1)	AU683881B2 (de)
CA (1)	CA2159728A1 (de)
DE (1)	DE69406441T2 (de)
DK (1)	DK0698041T3 (de)
ES (1)	ES2108444T3 (de)
GR (1)	GR3025446T3 (de)
HU (1)	HUT69700A (de)
IL (1)	IL109645A (de)
RU (1)	RU2126419C1 (de)
SI (1)	SI0698041T1 (de)
WO (1)	WO1994026780A1 (de)
ZA (1)	ZA943426B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE134379T1 (de) *	1990-12-05	1996-03-15	Lepetit Spa	38-decarboxy-38-hydroxymethylderivate von teicoplaninantibiotika, und verfahren zu deren herstellung
DK0912604T3 (da)	1996-04-23	2002-03-25	Biosearch Italia Spa	Forbedret kemisk fremgangsmåde til fremstilling af amidderivater af A 40926 antibiotikum
EP1095058A4 (de) *	1998-07-14	2003-07-16	Univ Princeton	Glykopeptidantibiotika, kombinatorische bibliotheken von glykopeptidantibiotika und verfahren zu ihrer herstellung
AU5141900A (en) *	1999-05-19	2000-12-05	Princeton University	Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4711877A (en) *	1985-09-18	1987-12-08	Smithkline Beckman Corporation	6-pen-vasopressin compounds
ES2110401T3 (es) *	1989-07-18	1998-02-16	Biosearch Italia Spa	Antibioticos pentapeptidicos derivados de dalbaheptidos.
DK0561827T3 (da) *	1990-12-10	1995-07-03	Lepetit Spa	Tetrapeptider stammende fra dalbaheptidantibiotika
US5438117A (en) *	1990-12-20	1995-08-01	Gruppo Lepetit S.P.A.	Hexapeptides deriving from aglucoteicoplanin and a process for preparing them

1994
- 1994-04-14 AU AU65689/94A patent/AU683881B2/en not_active Ceased
- 1994-04-14 AT AT94913599T patent/ATE159533T1/de not_active IP Right Cessation
- 1994-04-14 CA CA002159728A patent/CA2159728A1/en not_active Abandoned
- 1994-04-14 KR KR1019950705160A patent/KR100298136B1/ko not_active Expired - Fee Related
- 1994-04-14 SI SI9430101T patent/SI0698041T1/xx not_active IP Right Cessation
- 1994-04-14 DE DE69406441T patent/DE69406441T2/de not_active Expired - Fee Related
- 1994-04-14 DK DK94913599.0T patent/DK0698041T3/da active
- 1994-04-14 US US08/532,629 patent/US5674840A/en not_active Expired - Fee Related
- 1994-04-14 ES ES94913599T patent/ES2108444T3/es not_active Expired - Lifetime
- 1994-04-14 EP EP94913599A patent/EP0698041B1/de not_active Expired - Lifetime
- 1994-04-14 JP JP52485294A patent/JP3503066B2/ja not_active Expired - Fee Related
- 1994-04-14 WO PCT/EP1994/001154 patent/WO1994026780A1/en not_active Ceased
- 1994-04-14 RU RU95122178A patent/RU2126419C1/ru not_active IP Right Cessation
- 1994-04-14 HU HU9401939A patent/HUT69700A/hu unknown
- 1994-05-12 IL IL10964594A patent/IL109645A/xx not_active IP Right Cessation
- 1994-05-18 ZA ZA943426A patent/ZA943426B/xx unknown
1997
- 1997-11-19 GR GR970403091T patent/GR3025446T3/el unknown

Also Published As

Publication number	Publication date
DK0698041T3 (da)	1997-12-08
EP0698041A1 (de)	1996-02-28
DE69406441T2 (de)	1998-03-26
ES2108444T3 (es)	1997-12-16
KR960702475A (ko)	1996-04-27
JPH08510215A (ja)	1996-10-29
GR3025446T3 (en)	1998-02-27
HU9401939D0 (en)	1995-02-28
EP0698041B1 (de)	1997-10-22
AU683881B2 (en)	1997-11-27
DE69406441D1 (de)	1997-11-27
SI0698041T1 (en)	1998-02-28
WO1994026780A1 (en)	1994-11-24
RU2126419C1 (ru)	1999-02-20
AU6568994A (en)	1994-12-12
US5674840A (en)	1997-10-07
IL109645A0 (en)	1994-08-26
KR100298136B1 (ko)	2001-10-24
CA2159728A1 (en)	1994-11-24
HUT69700A (en)	1995-09-28
JP3503066B2 (ja)	2004-03-02
ATE159533T1 (de)	1997-11-15
ZA943426B (en)	1995-01-20

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Legal Events

Date	Code	Title
2000-11-21	FF	Patent granted
2001-04-30	KB	Patent renewed
2005-07-25	MM9K	Patent not in force due to non-payment of renewal fees