IL110913A - Method and apparatus for early embryonic in ovo injection - Google Patents

Method and apparatus for early embryonic in ovo injection

Info

Publication number: IL110913A
Authority: IL; Israel
Prior art keywords: egg; active agent; blocking member; shaft; shell
Prior art date: 1993-11-03

Application number

IL110913A

Other languages

English (en)

Other versions

IL110913A0 (en

Original Assignee

Embrex

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-03

Filing date

1994-09-09

Publication date

1998-04-05

1994-09-09 Application filed by Embrex filed Critical Embrex

1994-11-28 Publication of IL110913A0 publication Critical patent/IL110913A0/xx

1998-04-05 Publication of IL110913A publication Critical patent/IL110913A/en

Links

238000000034 method Methods 0.000 title claims abstract description 38
238000002347 injection Methods 0.000 title claims description 60
239000007924 injection Substances 0.000 title claims description 60
235000013601 eggs Nutrition 0.000 claims abstract description 147
239000013543 active substance Substances 0.000 claims abstract description 86
230000000903 blocking effect Effects 0.000 claims abstract description 74
150000001875 compounds Chemical class 0.000 claims abstract description 14
230000000149 penetrating effect Effects 0.000 claims abstract description 13
239000000853 adhesive Substances 0.000 claims abstract description 9
230000001070 adhesive effect Effects 0.000 claims abstract description 7
108010088751 Albumins Proteins 0.000 claims description 12
102000009027 Albumins Human genes 0.000 claims description 12
238000011534 incubation Methods 0.000 claims description 11
241000286209 Phasianidae Species 0.000 claims description 10
241000287828 Gallus gallus Species 0.000 claims description 7
229920002988 biodegradable polymer Polymers 0.000 claims description 5
239000004621 biodegradable polymer Substances 0.000 claims description 5
241000272517 Anseriformes Species 0.000 claims description 4
241000272534 Struthio camelus Species 0.000 claims description 4
-1 vaccines Substances 0.000 claims description 4
241000272525 Anas platyrhynchos Species 0.000 claims description 3
239000003242 anti bacterial agent Substances 0.000 claims description 3
239000002532 enzyme inhibitor Substances 0.000 claims description 3
239000005556 hormone Substances 0.000 claims description 3
229940088597 hormone Drugs 0.000 claims description 3
108090000765 processed proteins & peptides Proteins 0.000 claims description 3
229960005486 vaccine Drugs 0.000 claims description 3
239000011782 vitamin Substances 0.000 claims description 3
229940088594 vitamin Drugs 0.000 claims description 3
229930003231 vitamin Natural products 0.000 claims description 3
235000013343 vitamin Nutrition 0.000 claims description 3
229940088710 antibiotic agent Drugs 0.000 claims 2
210000000991 chicken egg Anatomy 0.000 claims 2
102000004196 processed proteins & peptides Human genes 0.000 claims 2
108010000912 Egg Proteins Proteins 0.000 abstract description 23
102000002322 Egg Proteins Human genes 0.000 abstract description 23
210000003278 egg shell Anatomy 0.000 abstract description 23
241000271566 Aves Species 0.000 abstract description 10
239000000565 sealant Substances 0.000 description 22
229920000642 polymer Polymers 0.000 description 14
238000007789 sealing Methods 0.000 description 8
239000000463 material Substances 0.000 description 7
229920000747 poly(lactic acid) Polymers 0.000 description 7
235000013330 chicken meat Nutrition 0.000 description 6
229920001577 copolymer Polymers 0.000 description 5
230000003115 biocidal effect Effects 0.000 description 4
229920006237 degradable polymer Polymers 0.000 description 4
230000008021 deposition Effects 0.000 description 4
239000012530 fluid Substances 0.000 description 4
210000004379 membrane Anatomy 0.000 description 4
239000012528 membrane Substances 0.000 description 4
244000144977 poultry Species 0.000 description 4
235000013594 poultry meat Nutrition 0.000 description 4
239000004590 silicone sealant Substances 0.000 description 4
239000000126 substance Substances 0.000 description 4
AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 3
229910000831 Steel Inorganic materials 0.000 description 3
ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 3
JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 3
239000000203 mixture Substances 0.000 description 3
229910001220 stainless steel Inorganic materials 0.000 description 3
239000010935 stainless steel Substances 0.000 description 3
239000010959 steel Substances 0.000 description 3
RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N Lactic Acid Natural products CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
229920000715 Mucilage Polymers 0.000 description 2
229920001244 Poly(D,L-lactide) Polymers 0.000 description 2
229920000954 Polyglycolide Polymers 0.000 description 2
XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
230000009286 beneficial effect Effects 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
230000001112 coagulating effect Effects 0.000 description 2
238000013270 controlled release Methods 0.000 description 2
238000012377 drug delivery Methods 0.000 description 2
239000000975 dye Substances 0.000 description 2
239000003292 glue Substances 0.000 description 2
238000010438 heat treatment Methods 0.000 description 2
210000001161 mammalian embryo Anatomy 0.000 description 2
231100000252 nontoxic Toxicity 0.000 description 2
230000003000 nontoxic effect Effects 0.000 description 2
229920001432 poly(L-lactide) Polymers 0.000 description 2
229910052710 silicon Inorganic materials 0.000 description 2
239000010703 silicon Substances 0.000 description 2
KVZLHPXEUGJPAH-UHFFFAOYSA-N 2-oxidanylpropanoic acid Chemical compound CC(O)C(O)=O.CC(O)C(O)=O KVZLHPXEUGJPAH-UHFFFAOYSA-N 0.000 description 1
241000272814 Anser sp. Species 0.000 description 1
241001379910 Ephemera danica Species 0.000 description 1
239000004831 Hot glue Substances 0.000 description 1
241000288147 Meleagris gallopavo Species 0.000 description 1
108010058846 Ovalbumin Proteins 0.000 description 1
239000002253 acid Substances 0.000 description 1
210000001643 allantois Anatomy 0.000 description 1
210000004381 amniotic fluid Anatomy 0.000 description 1
238000006065 biodegradation reaction Methods 0.000 description 1
230000004071 biological effect Effects 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
239000004568 cement Substances 0.000 description 1
239000002131 composite material Substances 0.000 description 1
239000000356 contaminant Substances 0.000 description 1
238000011109 contamination Methods 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
238000007598 dipping method Methods 0.000 description 1
230000006806 disease prevention Effects 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
229940125532 enzyme inhibitor Drugs 0.000 description 1
239000000989 food dye Substances 0.000 description 1
239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
238000007654 immersion Methods 0.000 description 1
230000001900 immune effect Effects 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000011159 matrix material Substances 0.000 description 1
235000013372 meat Nutrition 0.000 description 1
150000002894 organic compounds Chemical class 0.000 description 1
239000002245 particle Substances 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
230000001766 physiological effect Effects 0.000 description 1
229920001434 poly(D-lactide) Polymers 0.000 description 1
229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 description 1
229940065514 poly(lactide) Drugs 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
239000004633 polyglycolic acid Substances 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
239000011148 porous material Substances 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
235000008790 seltzer Nutrition 0.000 description 1
239000004945 silicone rubber Substances 0.000 description 1
239000007787 solid Substances 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000002255 vaccination Methods 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
150000003722 vitamin derivatives Chemical class 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K45/00—Other aviculture appliances, e.g. devices for determining whether a bird is about to lay
- A01K45/007—Injecting or otherwise treating hatching eggs

Landscapes

Life Sciences & Earth Sciences (AREA)
Environmental Sciences (AREA)
Birds (AREA)
Animal Husbandry (AREA)
Biodiversity & Conservation Biology (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Injection Moulding Of Plastics Or The Like (AREA)
Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Consolidation Of Soil By Introduction Of Solidifying Substances Into Soil (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Percussion Or Vibration Massage (AREA)
Catching Or Destruction (AREA)
Fuel-Injection Apparatus (AREA)

IL110913A 1993-11-03 1994-09-09 Method and apparatus for early embryonic in ovo injection IL110913A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/146,977 US5438954A (en)	1993-11-03	1993-11-03	Method and apparatus for early embryonic in ovo injection

Publications (2)

Publication Number	Publication Date
IL110913A0 IL110913A0 (en)	1994-11-28
IL110913A true IL110913A (en)	1998-04-05

Family

ID=22519836

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL110913A IL110913A (en)	1993-11-03	1994-09-09	Method and apparatus for early embryonic in ovo injection

Country Status (13)

Country	Link
US (1)	US5438954A (de)
EP (1)	EP0726705B1 (de)
JP (1)	JP3288047B2 (de)
AT (1)	ATE166530T1 (de)
AU (1)	AU681189B2 (de)
BR (1)	BR9407973A (de)
CA (1)	CA2175181A1 (de)
DE (1)	DE69410630T2 (de)
DK (1)	DK0726705T3 (de)
ES (1)	ES2117299T3 (de)
IL (1)	IL110913A (de)
WO (1)	WO1995012307A1 (de)
ZA (1)	ZA947440B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997013405A1 (en) *	1995-10-13	1997-04-17	The United States Of America, Represented By The Secretary Of Agriculture	In ovo yeast treatment to diminish salmonellae populations in poultry
US5807551A (en) *	1996-04-01	1998-09-15	Iowa State University Research Foundation, Inc.	Method to provide artificial passive immunity in birds
US5897998A (en) *	1997-08-04	1999-04-27	The University Of Georgia Research Foundation, Inc.	Method for manipulating avian eggs
US6286455B1 (en)	1998-01-12	2001-09-11	Embrex, Inc.	Automated in ovo injection apparatus
GB9822150D0 (en) *	1998-10-09	1998-12-02	Dignes Roy	Ultrasound driven devices for accelerated transfer of substances across porous boundaries
US6244214B1 (en) *	1999-01-06	2001-06-12	Embrex, Inc.	Concurrent in ovo injection and detection method and apparatus
US6682754B2 (en)	1999-11-24	2004-01-27	Willmar Poultry Company, Inc.	Ovo delivery of an immunogen containing implant
US6565533B1 (en)	2000-01-21	2003-05-20	Novus International, Inc.	Inoculation apparatus and method
EP1129617A1 (de)	2000-02-15	2001-09-05	Ovo Biosciences, Inc.	Methode um ein Vogelei in der Schale zu fertilisieren
US6354242B1 (en) *	2000-03-23	2002-03-12	North Carolina State University	Methods for gamete production in birds
US6397777B1 (en)	2001-02-14	2002-06-04	University Of Georgia Research Foundation, Inc.	Method for windowing eggs
US6499428B1 (en)	2001-07-31	2002-12-31	Ideal Instruments, Inc.	Quick disconnect, disposable needle and hub assembly
EP1425386A4 (de) *	2001-08-13	2007-05-02	Embrex Inc	Verfahren zur injektion von vogeleiern
US6729265B2 (en) *	2002-06-27	2004-05-04	Arkion Life Sciences Llc	Supplemented antibody feed to enter the circulating system of newborns
US6858020B2 (en) *	2002-07-08	2005-02-22	Ideal Instrument, Inc.	Vaccinator device
US7638841B2 (en)	2003-05-20	2009-12-29	Fairchild Semiconductor Corporation	Power semiconductor devices and methods of manufacture
US7261053B2 (en) *	2004-04-03	2007-08-28	Merial Limited	Methods and apparatus for automatic jet injection of bird eggs
US7617795B2 (en) *	2004-10-13	2009-11-17	Embrex, Inc.	Methods and apparatus for injecting and sampling material through avian egg membranes
TWI297660B (en) *	2004-11-29	2008-06-11	Compact Automation Products Llc	Integrated pneumatic actuator and pump for dispensing controlled amounts of a fluid
US20060196428A1 (en) *	2005-03-03	2006-09-07	Correa Rafael S	Method for improving chick hatchability
AU2006279612B2 (en)	2005-08-15	2013-03-21	Altimmune Inc.	Immunization of avians by administration of non-replicating vectored vaccines
EP2124533B1 (de)	2007-01-10	2016-01-06	Natratec International Ltd.	Verfahren und zusammensetzungen für die verbesserung der schlupffähigkeit von brutanstalteiern
NL2003422C2 (nl) *	2009-09-02	2011-03-03	Visser S Gravendeel Holding	Werkwijze voor het prepareren van een invasieve test op een ei en voor het bepalen van de sexe van een embryo in een ei.
CN107047459A (zh) *	2017-03-28	2017-08-18	枞阳县横山生态农业有限公司	一种提升肉仔鸡生长特性的孵化方法
WO2020106224A1 (en) *	2018-11-23	2020-05-28	K Fresh Co., Ltd	Assembly for accessing coconut water in coconut
NL2024700B1 (en) *	2020-01-17	2021-09-08	In Ovo Holding B V	Egg Sampling Device
WO2025059741A1 (pt)	2023-09-19	2025-03-27	Ion - In-Ovo Nutrition Industria E Comercio De Nutricao Animal E Equipamentos Ltda	Aperfeiçoamento aplicado em dispositivo de sanitização aplicado em módulo e dispositivo de injeção intra-ovo de substâncias de interesse e sua lógica operacional
WO2025059742A1 (pt)	2023-09-19	2025-03-27	Ion - In-Ovo Nutrition Industria E Comercio De Nutricao Animal E Equipamentos Ltda	Aperfeiçoamento aplicado em perfurador de dispositivo injetor intra-ovo de substâncias de interesse, notadamente em disposição construtiva para sanitização da totalidade das áreas interna e externa da cânula de perfuração e sua lógica operacional de sanitização

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US2734482A (en) *		1956-02-14		The method of controlling the sex of
US1756453A (en) *	1927-10-10	1930-04-29	Davey Tree Expert Company	Method of treating trees and apparatus therefor
US2477752A (en) *	1947-04-08	1949-08-02	William A Weiss	Method of treating eggs to produce chicks having coloeed down
US3136314A (en) *	1960-08-01	1964-06-09	Kravitz Harvey	Vaccinating devices
US3256856A (en) *	1964-08-19	1966-06-21	Francis C Moore	Method of introducing small controlled amounts of treatment materials into avian eggs
US3377989A (en) *	1966-08-08	1968-04-16	American Cyanamid Co	Automatic egg inoculating unit
US4040388A (en) *	1976-02-27	1977-08-09	Agrimatic Corporation	Method and apparatus for automatic egg injection
US4966159A (en) *	1981-12-14	1990-10-30	Maganias Nicholas H	Allergy test strip
US4593646A (en) *	1982-06-01	1986-06-10	Agrimatic Corporation	Egg injection method and apparatus
US4755173A (en) *	1986-02-25	1988-07-05	Pacesetter Infusion, Ltd.	Soft cannula subcutaneous injection set
US4903635A (en) *	1986-07-02	1990-02-27	Embrex, Inc.	High speed automated injection system for avian embryos
US4681063A (en) *	1986-07-02	1987-07-21	Embrex Inc.	High speed automated injection system for avian embryos
US4928628A (en) *	1988-06-13	1990-05-29	Iowa State University Research Foundation, Inc.	Egg inoculation device and method of using same
US4928629A (en) *	1988-06-13	1990-05-29	Iowa State University Research Foundation, Inc.	Egg inoculation method
US5056454A (en) *	1989-06-22	1991-10-15	Turner Lance H	Utility locator
US5056464A (en) *	1990-01-18	1991-10-15	Embrex, Inc.	Automated injection system for avian embryos with advanced fluid delivery system
US5136979A (en) *	1991-09-25	1992-08-11	Embrex, Inc.	Modular injection system for avian embryos
US5176648A (en) *	1991-12-13	1993-01-05	Unisurge, Inc.	Introducer assembly and instrument for use therewith

1993
- 1993-11-03 US US08/146,977 patent/US5438954A/en not_active Expired - Lifetime
1994
- 1994-08-29 DK DK94927256T patent/DK0726705T3/da active
- 1994-08-29 JP JP51319695A patent/JP3288047B2/ja not_active Expired - Fee Related
- 1994-08-29 ES ES94927256T patent/ES2117299T3/es not_active Expired - Lifetime
- 1994-08-29 WO PCT/US1994/009696 patent/WO1995012307A1/en not_active Ceased
- 1994-08-29 EP EP94927256A patent/EP0726705B1/de not_active Expired - Lifetime
- 1994-08-29 AT AT94927256T patent/ATE166530T1/de not_active IP Right Cessation
- 1994-08-29 DE DE69410630T patent/DE69410630T2/de not_active Expired - Fee Related
- 1994-08-29 AU AU76759/94A patent/AU681189B2/en not_active Ceased
- 1994-08-29 BR BR9407973A patent/BR9407973A/pt not_active Application Discontinuation
- 1994-08-29 CA CA002175181A patent/CA2175181A1/en not_active Abandoned
- 1994-09-09 IL IL110913A patent/IL110913A/en not_active IP Right Cessation
- 1994-09-23 ZA ZA947440A patent/ZA947440B/xx unknown

Also Published As

Publication number	Publication date
AU7675994A (en)	1995-05-23
ATE166530T1 (de)	1998-06-15
DK0726705T3 (da)	1999-03-01
DE69410630D1 (de)	1998-07-02
AU681189B2 (en)	1997-08-21
WO1995012307A1 (en)	1995-05-11
ZA947440B (en)	1995-05-16
BR9407973A (pt)	1996-12-03
EP0726705A1 (de)	1996-08-21
DE69410630T2 (de)	1999-01-07
JPH09505994A (ja)	1997-06-17
US5438954A (en)	1995-08-08
CA2175181A1 (en)	1995-05-11
EP0726705B1 (de)	1998-05-27
ES2117299T3 (es)	1998-08-01
IL110913A0 (en)	1994-11-28
JP3288047B2 (ja)	2002-06-04

Legal Events

Date	Code	Title
1998-10-30	FF	Patent granted
1999-03-12	KB	Patent renewed
2001-06-14	RH	Patent void

Publication	Publication Date	Title
US5438954A (en)	1995-08-08	Method and apparatus for early embryonic in ovo injection
AU681697B2 (en)	1997-09-04	Method of introducing material into eggs during early embryonic development
AU678147B2 (en)	1997-05-22	Gene transfer in birds by introduction of DNA into muscle in ovo
US6682754B2 (en)	2004-01-27	Ovo delivery of an immunogen containing implant
EP1122997B1 (de)	2004-06-23	Verfahren zur lokalisierung von allantoisflüssigkeit in geflügeleiern
US5206015A (en)	1993-04-27	Introduction of bacteria in ovo
EP1737294A2 (de)	2007-01-03	Verfahren und vorrichtung zur automatischen jet-injektion von vogeleiern
IL94445A (en)	1996-10-16	Method of inducing an immature bird to gain weight
EP0628307A2 (de)	1994-12-14	Verfahren zur Verabreichung biologischer Stoffe sowie Mikropartikeln zur Verwendung in diesen und weiteren Verfahren