IL112098A - SULFAMIC ACID ESTERS OF PSEUDO-b-FRUCTOPYRANOSE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

SULFAMIC ACID ESTERS OF PSEUDO-b-FRUCTOPYRANOSE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number: IL112098A
Authority: IL; Israel
Prior art keywords: fructopyranose; pseudo; pharmaceutical compositions; acid esters; compositions containing
Prior art date: 1993-12-23

Application number

IL112098A

Other languages

English (en)

Other versions

IL112098A0 (en

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-23

Filing date

1994-12-21

Publication date

1997-07-13

1994-11-10 Priority claimed from US08/337,597 external-priority patent/US5498629A/en

1994-12-21 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1995-03-15 Publication of IL112098A0 publication Critical patent/IL112098A0/xx

1997-07-13 Publication of IL112098A publication Critical patent/IL112098A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical class NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
239000011593 sulfur Substances 0.000 abstract 2
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
230000001773 anti-convulsant effect Effects 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
229960003965 antiepileptics Drugs 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Steroid Compounds (AREA)
Hydrogenated Pyridines (AREA)
Confectionery (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Detergent Compositions (AREA)

IL112098A 1993-12-23 1994-12-21 SULFAMIC ACID ESTERS OF PSEUDO-b-FRUCTOPYRANOSE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL112098A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17339993A	1993-12-23	1993-12-23
US08/337,597 US5498629A (en)	1993-12-23	1994-11-10	Anticonvulsant pseudofructopyranose sulfamates

Publications (2)

Publication Number	Publication Date
IL112098A0 IL112098A0 (en)	1995-03-15
IL112098A true IL112098A (en)	1997-07-13

Family

ID=26869093

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL112098A IL112098A (en)	1993-12-23	1994-12-21	SULFAMIC ACID ESTERS OF PSEUDO-b-FRUCTOPYRANOSE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (13)

Country	Link
EP (1)	EP0736029B1 (fr)
JP (1)	JP3555032B2 (fr)
AT (1)	ATE319715T1 (fr)
AU (1)	AU695336B2 (fr)
CA (1)	CA2179733C (fr)
DE (1)	DE69434652T2 (fr)
DK (1)	DK0736029T3 (fr)
ES (1)	ES2260761T3 (fr)
IL (1)	IL112098A (fr)
NZ (1)	NZ277725A (fr)
PT (1)	PT736029E (fr)
RU (1)	RU2139875C1 (fr)
WO (1)	WO1995017406A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000061138A1 (fr) *	1999-04-08	2000-10-19	Ortho-Mcneil Pharmaceutical, Inc.	Derives anticonvulsivants utiles pour traiter des etats neurodegeneratifs chroniques
EP1204669B1 (fr)	1999-07-26	2005-11-09	Ortho-McNeil Pharmaceutical, Inc.	Derives de monosaccharide tricycliques utiles dans le traitement des maladies neurodegeneratives induites par l'ischemie aigue
DE60219961T8 (de) *	2001-02-02	2008-04-17	Ortho-Mcneil Pharmaceutical, Inc.	Behandlung von neurologischen funktionsstörungen mit fructopyranosesulfamaten und erythropoetin
WO2003039563A1 (fr) *	2001-11-06	2003-05-15	Ortho-Mcneil Pharmaceutical Inc.	Traitement et prevention de paresthesie comprenant une therapie associant des derives anticonvulsivants et du potassium
US7060725B2 (en) *	2002-05-13	2006-06-13	Janssen Pharmaceutica N.V.	Substituted sulfamate anticonvulsant derivatives
MY147767A (en)	2004-06-16	2013-01-31	Janssen Pharmaceutica Nv	Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
KR20080012360A (ko)	2005-05-20	2008-02-11	얀센 파마슈티카 엔.브이.	설파미드 유도체의 제조 방법
US8937096B2 (en)	2005-12-19	2015-01-20	Janssen Pharmaceutica Nv	Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8497298B2 (en)	2005-12-19	2013-07-30	Janssen Pharmaceutica Nv	Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8716231B2 (en)	2005-12-19	2014-05-06	Janssen Pharmaceutica Nv	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8492431B2 (en)	2005-12-19	2013-07-23	Janssen Pharmaceutica, N.V.	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8691867B2 (en)	2005-12-19	2014-04-08	Janssen Pharmaceutica Nv	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
EA200870556A1 (ru)	2006-05-19	2009-06-30	Янссен Фармацевтика Н.В.	Комбинированная терапия в лечении эпилепсии и родственных расстройств
EA018567B1 (ru)	2008-06-23	2013-08-30	Янссен Фармацевтика Нв	Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида
US8815939B2 (en)	2008-07-22	2014-08-26	Janssen Pharmaceutica Nv	Substituted sulfamide derivatives
KR101792999B1 (ko) *	2013-12-12	2017-11-02	(주)바이오팜솔루션즈	간질 예방 또는 치료용 설파메이트 유도체 화합물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3997585A (en) *	1974-12-30	1976-12-14	Ortho Pharmaceutical Corporation	Aliphatic sulfamates
US4513006A (en) *	1983-09-26	1985-04-23	Mcneil Lab., Inc.	Anticonvulsant sulfamate derivatives
US4792569A (en) *	1987-08-27	1988-12-20	Mcneilab, Inc.	Anticonvulsant phenethyl sulfamates
US5242942A (en) *	1992-04-28	1993-09-07	Mcneilab, Inc.	Anticonvulsant fructopyranose cyclic sulfites and sulfates

1994
- 1994-12-15 CA CA002179733A patent/CA2179733C/fr not_active Expired - Fee Related
- 1994-12-15 PT PT95904333T patent/PT736029E/pt unknown
- 1994-12-15 AU AU13067/95A patent/AU695336B2/en not_active Ceased
- 1994-12-15 NZ NZ277725A patent/NZ277725A/en not_active IP Right Cessation
- 1994-12-15 WO PCT/US1994/014591 patent/WO1995017406A1/fr not_active Ceased
- 1994-12-15 DK DK95904333T patent/DK0736029T3/da active
- 1994-12-15 ES ES95904333T patent/ES2260761T3/es not_active Expired - Lifetime
- 1994-12-15 AT AT95904333T patent/ATE319715T1/de not_active IP Right Cessation
- 1994-12-15 DE DE69434652T patent/DE69434652T2/de not_active Expired - Fee Related
- 1994-12-15 EP EP95904333A patent/EP0736029B1/fr not_active Expired - Lifetime
- 1994-12-15 JP JP51752695A patent/JP3555032B2/ja not_active Expired - Fee Related
- 1994-12-15 RU RU96115166A patent/RU2139875C1/ru not_active IP Right Cessation
- 1994-12-21 IL IL112098A patent/IL112098A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
RU2139875C1 (ru)	1999-10-20
CA2179733A1 (fr)	1995-06-29
WO1995017406A1 (fr)	1995-06-29
EP0736029A1 (fr)	1996-10-09
CA2179733C (fr)	2007-03-27
DE69434652D1 (de)	2006-05-04
AU695336B2 (en)	1998-08-13
ES2260761T3 (es)	2006-11-01
DK0736029T3 (da)	2006-05-15
NZ277725A (en)	1998-04-27
ATE319715T1 (de)	2006-03-15
EP0736029B1 (fr)	2006-03-08
JP3555032B2 (ja)	2004-08-18
PT736029E (pt)	2006-05-31
IL112098A0 (en)	1995-03-15
DE69434652T2 (de)	2007-03-01
JPH09507070A (ja)	1997-07-15
AU1306795A (en)	1995-07-10

Legal Events

Date	Code	Title
1998-02-08	FF	Patent granted
1998-04-05	KB	Patent renewed
2009-07-20	KB	Patent renewed
2013-08-29	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL112098A (en)	1997-07-13	SULFAMIC ACID ESTERS OF PSEUDO-b-FRUCTOPYRANOSE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA2203942A1 (fr)	1993-02-21	Derive de pyrrolidylthiocarbapeneme
BG101460A (bg)	1998-08-31	Естери на 2-цианакрилова киселина
HU9502811D0 (en)	1995-11-28	N-acyl-sulfamic acid esters (or thioesters), n-acyl-sulfonamides and n-sulfonyl-carbamic-acid-esters (or thioesters) as hypercholesterolemic agents
CA2086175A1 (fr)	1993-06-27	Poly(tetramethylxylylenecarbodiimide)
GB9300366D0 (en)	1993-03-03	Compositions and uses thereof
IE791895L (en)	1980-04-23	Alkanoyl prolines.
EP0322182A3 (fr)	1992-01-02	Composés azabicycliques, procédé pour leur préparation et compositions pharmaceutiques les contenant
MY113732A (en)	2002-05-31	Arylthio compounds
CA2188283A1 (fr)	1995-11-02	1,3-oxathiolanes substituees a proprietes antivirales
JPS568361A (en)	1981-01-28	Pyroglutamic acid derivative and analogue
HUT46313A (en)	1988-10-28	Process for producing 3/2h/-pyridazine derivatives and pharmaceutical compositions containing them as active components
IL105111A (en)	1997-03-18	SEMI-SYNTHETIC GLYCOSAMINOGLYCANS CONTAINING a-L- GALACTURONIC ACID SUBSTITUTED WITH NUCLEOPHILIC RADICALS IN POSITION 3 AND THEIR PREPARATION
CA2151149A1 (fr)	1994-07-07	Nouveaux monomeres pour l'ouverture de cycles
ES2044781A1 (es)	1994-01-01	Procedimiento para la preparacion de nuevas amidas con accion inhibidora de la fosfolipasa a2
ES8605810A1 (es)	1986-04-01	Un procedimiento para la preparacion de compuestos de beta-lactama
AU2177997A (en)	1997-10-29	Anticachectic composition
IE781926L (en)	1979-04-03	Peptides analgesics
GR3007460T3 (fr)	1993-07-30
ES467697A1 (es)	1979-07-01	Procedimiento para la obtencion de protectores contra la in-flamacion a base de derivados del acido fosfonocarboxilico
CA2247946A1 (fr)	1997-10-16	Composition anticachexique
HU9503090D0 (en)	1995-12-28	Novel bisoxadiazolidine derivative
ZA912618B (en)	1992-01-29	3-aminochroman derivatives,process for preparing these and pharmaceutical compositions containing them
ES8400109A1 (es)	1983-10-16	"un procedimiento para preparar esteres de acido 3-metilflavon-8-carboxilico".
ES8206457A1 (es)	1982-08-16	Un procedimiento para la preparacion de compuestos n-acil-n- (cicloalquil) aminoacidos.