IL113112A - Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them - Google Patents

Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them

Info

Publication number: IL113112A
Authority: IL; Israel
Prior art keywords: group; alkyl; cycloalkyl; thiazolidinediones; pharmaceutical compositions
Prior art date: 1994-03-28

Application number

IL11311295A

Other languages

English (en)

Other versions

IL113112A0 (en

Original Assignee

Nissan Chemical Ind Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-28

Filing date

1995-03-23

Publication date

2000-06-01

1995-03-23 Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd

1995-06-29 Publication of IL113112A0 publication Critical patent/IL113112A0/xx

2000-06-01 Publication of IL113112A publication Critical patent/IL113112A/xx

Links

JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title abstract 4
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title abstract 2
229940123464 Thiazolidinedione Drugs 0.000 title 1
239000008194 pharmaceutical composition Chemical class 0.000 title 1
150000001467 thiazolidinediones Chemical class 0.000 title 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 4
125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 3
125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
125000005865 C2-C10alkynyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
-1 alpha -naphthyl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000006267 biphenyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002218 hypoglycaemic effect Effects 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
150000003548 thiazolidines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL11311295A 1994-03-28 1995-03-23 Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them IL113112A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP5719294		1994-03-28
JP29517794		1994-11-29

Publications (2)

Publication Number	Publication Date
IL113112A0 IL113112A0 (en)	1995-06-29
IL113112A true IL113112A (en)	2000-06-01

Family

ID=26398213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11311295A IL113112A (en)	1994-03-28	1995-03-23	Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them

Country Status (19)

Country	Link
EP (1)	EP0751944B1 (cs)
KR (1)	KR100340615B1 (cs)
CN (1)	CN1045776C (cs)
AT (1)	ATE198200T1 (cs)
AU (1)	AU683739B2 (cs)
CA (1)	CA2186381A1 (cs)
CZ (1)	CZ282096A3 (cs)
DE (1)	DE69519666T2 (cs)
DK (1)	DK0751944T3 (cs)
ES (1)	ES2154727T3 (cs)
GR (1)	GR3035277T3 (cs)
HU (1)	HUT76062A (cs)
IL (1)	IL113112A (cs)
MX (1)	MX9604430A (cs)
NZ (1)	NZ282893A (cs)
PT (1)	PT751944E (cs)
RU (1)	RU2125053C1 (cs)
TW (1)	TW420669B (cs)
WO (1)	WO1995026347A1 (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK280914B6 (sk) *	1994-03-08	2000-09-12	American Home Products Corporation	Tiazolidíndiónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
ZA973850B (en) *	1996-05-06	1997-12-02	Reddy Research Foundation	Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5919782A (en) *	1996-05-06	1999-07-06	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973848B (en) *	1996-05-06	1997-12-02	Reddy Research Foundation	Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US6372750B2 (en)	1996-07-01	2002-04-16	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) *	1996-07-01	2006-09-05	Dr. Reddy's Laboratories, Limited	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
AU744518B2 (en)	1996-07-01	2002-02-28	Dr. Reddy's Laboratories Limited	Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) *	1996-07-01	2000-09-05	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6313113B1 (en)	1997-04-15	2001-11-06	Reddy-Cheminor, Inc.	Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6011031A (en) *	1997-05-30	2000-01-04	Dr. Reddy's Research Foundation	Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
US6756360B1 (en)	1998-12-24	2004-06-29	Metabasis Therapeutics, Inc.	Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes
US7563774B2 (en)	2000-06-29	2009-07-21	Metabasis Therapeutics, Inc.	Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
EA200300379A1 (ru)	2000-11-27	2003-08-28	Пфайзер Продактс Инк.	Селективные агонисты рецептора ep4 в лечении остеопороза
GB0122318D0 (en) *	2001-09-14	2001-11-07	Novartis Ag	Organic compounds
ES2309383T3 (es) *	2003-01-02	2008-12-16	Hoffmann La Roche	Pirrolil tiazoles y su empleo como agonistas inversos de receptores cb1.
US7691888B2 (en) *	2004-10-07	2010-04-06	Boehringer Ingelheim International Gmbh	Thiazolyl-dihydro-indazole
RS53981B1 (sr) *	2006-03-24	2015-10-30	Array Biopharma Inc.	Analozi 2-aminopiridina kao aktivatori glukokinaze
CN101311167B (zh) *	2007-05-25	2011-04-06	天津药物研究院	1-苯基咪唑烷-2,4-二酮类衍生物及其用途
WO2011079274A1 (en)	2009-12-23	2011-06-30	Jasco Pharmaceuticals, LLC	Aminopyrimidine kinase inhibitors
WO2012145617A2 (en)	2011-04-22	2012-10-26	Jasco Pharmaceuticals, LLC	Aminopyrimidine kinase inhibitors
BR112014010563B1 (pt)	2011-11-04	2021-01-12	Jasco Pharmaceuticals, LLC	compostos inibidores da aminopirimidina quinase
KR20160004272U (ko)	2015-06-04	2016-12-14	심명보	걸이구가 구비된 케이블행거
KR200488728Y1 (ko)	2017-06-15	2019-03-11	심명보	걸이구가 구비된 케이블행거
IL272246B2 (en)	2017-07-28	2026-01-01	Applied Therapeutics Inc	History of 2-(4-oxo/thioketone/azo-3-((substituted)benzo[d]thiazol-2-yl)methyl)- 3,4-dihydrothieno[3,4-d]pyridazin-1-yl)acetic acid for use as an aldose reductase inhibitor for the treatment of galactosemia or prevention of galactosemia-related complications
CN113840825A (zh)	2019-04-01	2021-12-24	应用治疗公司	醛糖还原酶抑制剂
MX2021013511A (es)	2019-05-07	2022-02-23	Univ Miami	Tratamiento y deteccion de neuropatias heredadas y trastornos asociados.
KR102433164B1 (ko) *	2020-06-29	2022-08-18	한국전력공사	길이와 각도 조절이 가능한 케이블 행거

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5564586A (en) *	1978-11-09	1980-05-15	Takeda Chem Ind Ltd	Thiazolidine derivative
FI904414A7 (fi) *	1988-03-08	1990-09-07	Pfizer	Tiatsolidiinidioni-hypoglykeemisesti vaikuttavat aineet
WO1989008651A1 (en) *	1988-03-08	1989-09-21	Pfizer Inc.	Hypoglycemic thiazolidinedione derivatives
JPH065228A (ja) *	1992-06-18	1994-01-14	Mitsubishi Electric Corp	偏向デバイス
TW245716B (cs) *	1992-12-28	1995-04-21	Takeda Pharm Industry Co
KR960002625A (ko) *	1994-06-17	1996-01-26	제임스 조셉 드롱	다층 레지스트의 플라즈마 에칭을 위한 방법 및 장치

1995
- 1995-03-23 IL IL11311295A patent/IL113112A/xx not_active IP Right Cessation
- 1995-03-23 TW TW084102837A patent/TW420669B/zh not_active IP Right Cessation
- 1995-03-27 CA CA002186381A patent/CA2186381A1/en not_active Abandoned
- 1995-03-27 CZ CZ962820A patent/CZ282096A3/cs unknown
- 1995-03-27 RU RU96119770A patent/RU2125053C1/ru not_active IP Right Cessation
- 1995-03-27 MX MX9604430A patent/MX9604430A/es unknown
- 1995-03-27 DK DK95913343T patent/DK0751944T3/da active
- 1995-03-27 DE DE69519666T patent/DE69519666T2/de not_active Expired - Fee Related
- 1995-03-27 AT AT95913343T patent/ATE198200T1/de not_active IP Right Cessation
- 1995-03-27 CN CN95192264A patent/CN1045776C/zh not_active Expired - Fee Related
- 1995-03-27 WO PCT/JP1995/000560 patent/WO1995026347A1/en not_active Ceased
- 1995-03-27 EP EP95913343A patent/EP0751944B1/en not_active Expired - Lifetime
- 1995-03-27 ES ES95913343T patent/ES2154727T3/es not_active Expired - Lifetime
- 1995-03-27 PT PT95913343T patent/PT751944E/pt unknown
- 1995-03-27 NZ NZ282893A patent/NZ282893A/en unknown
- 1995-03-27 AU AU20833/95A patent/AU683739B2/en not_active Ceased
- 1995-03-27 HU HU9602645A patent/HUT76062A/hu unknown
- 1995-03-27 KR KR1019960705283A patent/KR100340615B1/ko not_active Expired - Fee Related
2001
- 2001-01-18 GR GR20010400094T patent/GR3035277T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU9602645D0 (en)	1996-11-28
MX9604430A (es)	1997-12-31
ES2154727T3 (es)	2001-04-16
CN1045776C (zh)	1999-10-20
DE69519666D1 (de)	2001-01-25
NZ282893A (en)	1997-07-27
DK0751944T3 (da)	2001-01-08
GR3035277T3 (en)	2001-04-30
PT751944E (pt)	2001-03-30
HUT76062A (en)	1997-06-30
ATE198200T1 (de)	2001-01-15
EP0751944B1 (en)	2000-12-20
AU2083395A (en)	1995-10-17
EP0751944A1 (en)	1997-01-08
KR970701716A (ko)	1997-04-12
CN1144526A (zh)	1997-03-05
KR100340615B1 (ko)	2002-10-18
CZ282096A3 (en)	1997-03-12
AU683739B2 (en)	1997-11-20
CA2186381A1 (en)	1995-10-05
RU2125053C1 (ru)	1999-01-20
IL113112A0 (en)	1995-06-29
DE69519666T2 (de)	2001-04-26
TW420669B (en)	2001-02-01
WO1995026347A1 (en)	1995-10-05

Legal Events

Date	Code	Title	Description
2000-11-21	FF	Patent granted
2006-01-15	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL113112A0 (en)	1995-06-29	Pyridine type thiazolidines
AU583651B2 (en)	1989-05-04	Novel nitromethylene derivatives
HU907896D0 (en)	1991-08-28	Amine derivatives
MX9709951A (es)	1998-03-29	Derivados de benzamida y su uso como antagonistas de vasopresina.
TW200420542A (en)	2004-10-16	A compound having TGF β inhibition activity and a medicinal composition containing the same
HU9700030D0 (en)	1997-02-28	2-(1',2',4'-triazol-3'-yloxymethylene)-anilides and their use as pestcontrol agents
NZ332658A (en)	2000-05-26	Halo-substituted bis-indolylmaleimide derivatives and pharmaceutical compositions
GB9408185D0 (en)	1994-06-15	New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
ES8103070A1 (es)	1981-02-16	Un procedimiento para preparar un compuesto de guanidinotia-zol
EP1022272A4 (en)	2002-07-17	SUBSTITUTED CONDENSED HETEROCYCLIC COMPOUNDS
EP0712398A1 (en)	1996-05-22	BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
KR960706476A (ko)	1996-12-09	인터류킨-1 활성 억제제로서의 신규한 벤젠설포닐아민 유도체(Novel benzen-esulfonylimine derivatives as inhibitors of lL-1 action)
IL125926A0 (en)	1999-04-11	Compounds related to the amidinium family pharmaceutical compositions containing them and uses thereof
ATE104661T1 (de)	1994-05-15	Thioformamid-derivate.
HUT59560A (en)	1992-06-29	Insecticide and acaricide composition containing heterocyclic active component and process for producing intermediates for the active components
IL66239A0 (en)	1982-11-30	Synergistic compositions and method for selectively combating weeds,especially in cereal crops
ES2024332A6 (es)	1992-02-16	Procedimiento para la obtencion de nuevas sulfonamidas.
EP0293839A3 (en)	1989-10-25	Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient
AU653019B2 (en)	1994-09-15	New urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
AU1287892A (en)	1992-09-24	Method of inhibiting the progressive development of diabetes mellitus
JPS55167206A (en)	1980-12-26	Industrial bactericidal and fungicidal agent
MX9603868A (es)	1997-03-29	Composicion farmaceutica de derivados de indeno para la regulacion de la apoptosis.
IL91359A (en)	1997-03-18	S-(n-substituted) aminomethyl isothiourea derivatives, useful as intermediates for 1,3,5 - thiadiazine-4-one derivatives
ATE44741T1 (de)	1989-08-15	2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.