IL113365A - 5-Heterocyclo-1,5-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them - Google Patents

5-Heterocyclo-1,5-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number: IL113365A
Authority: IL; Israel
Prior art keywords: preparation; heterocyclo; pharmaceutical compositions; compositions containing; benzodiazepine derivatives
Prior art date: 1994-04-14

Application number

IL11336595A

Other languages

English (en)

Other versions

IL113365A0 (en

Original Assignee

Glaxo Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-14

Filing date

1995-04-13

Publication date

1999-11-30

1994-04-14 Priority claimed from GB9407433A external-priority patent/GB9407433D0/en

1994-10-14 Priority claimed from GB9420783A external-priority patent/GB9420783D0/en

1995-04-13 Application filed by Glaxo Inc filed Critical Glaxo Inc

1995-07-31 Publication of IL113365A0 publication Critical patent/IL113365A0/xx

1999-11-30 Publication of IL113365A publication Critical patent/IL113365A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Emergency Medicine (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

IL11336595A 1994-04-14 1995-04-13 5-Heterocyclo-1,5-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them IL113365A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9407433A GB9407433D0 (en)	1994-04-14	1994-04-14	Heterocyclic derivatives
GB9420783A GB9420783D0 (en)	1994-10-14	1994-10-14	Heterocyclic derivatives

Publications (2)

Publication Number	Publication Date
IL113365A0 IL113365A0 (en)	1995-07-31
IL113365A true IL113365A (en)	1999-11-30

Family

ID=26304703

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11336595A IL113365A (en)	1994-04-14	1995-04-13	5-Heterocyclo-1,5-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them

Country Status (25)

Country	Link
EP (1)	EP0756602B1 (de)
JP (1)	JPH09511223A (de)
KR (1)	KR970702274A (de)
CN (1)	CN1176646A (de)
AT (1)	ATE181737T1 (de)
AU (1)	AU697349B2 (de)
BR (1)	BR9507381A (de)
CA (1)	CA2186900A1 (de)
CZ (1)	CZ286764B6 (de)
DE (1)	DE69510545T2 (de)
DK (1)	DK0756602T3 (de)
ES (1)	ES2135722T3 (de)
FI (1)	FI964045L (de)
GR (1)	GR3031335T3 (de)
HU (1)	HUT76135A (de)
IL (1)	IL113365A (de)
IS (1)	IS4367A (de)
MX (1)	MX9604765A (de)
NO (1)	NO964348L (de)
NZ (1)	NZ283929A (de)
PL (1)	PL180026B1 (de)
RU (1)	RU2152939C1 (de)
SK (1)	SK281433B6 (de)
TW (1)	TW369529B (de)
WO (1)	WO1995028419A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9307833D0 (en) *	1993-04-15	1993-06-02	Glaxo Inc	Modulators of cholecystokinin and gastrin
PE27497A1 (es) *	1994-04-15	1997-08-07	Glaxo Inc	Derivados de 1,5 benzodiazepina
PT945445E (pt) *	1996-12-10	2004-01-30	Zeria Pharm Co Ltd	Derivados de 1,5-benzodiazepina
US7910548B2 (en) *	1997-06-06	2011-03-22	Amylin Pharmaceuticals, Inc.	Methods for treating obesity
EP1123928A4 (de) *	1998-10-20	2005-02-16	Takeda Pharmaceutical	1,5-benzodiazepin-verbindungen, verfahren zu ihrer herstellung und eine medizin
JP4535350B2 (ja) *	1998-11-17	2010-09-01	クミアイ化学工業株式会社	ピリミジニルベンズイミダゾール誘導体及び農園芸用殺菌剤
ATE402700T1 (de) *	2002-08-27	2008-08-15	Merck Patent Gmbh	Glycinamid-derivate als raf-kinase-hemmer
AP2006003768A0 (en)	2004-05-25	2006-10-31	Pfizer Prod Inc	TetraazabenzoÄeÜazulene derivatives and analogs tehereof
RU2303597C1 (ru) *	2006-05-12	2007-07-27	Иващенко Андрей Александрович	Фармацевтическая композиция, способы ее получения и применения
JP6207399B2 (ja)	2012-01-13	2017-10-04	日本ケミファ株式会社	Ｐ２ｘ４受容体拮抗剤
IL287136B2 (en)	2016-02-05	2023-09-01	Denali Therapeutics Inc	Receptor inhibitors - interacting with protein kinase 1
JP7208137B2 (ja)	2016-12-09	2023-01-18	デナリセラピューティクスインコーポレイテッド	化合物、組成物および方法
KR20220150270A (ko)	2019-10-07	2022-11-10	칼리오페, 인크.	Gpr119 효능제
TW202140440A (zh)	2020-02-28	2021-11-01	美商克力歐普股份有限公司	Gpr40激動劑
TW202334164A (zh)	2022-01-12	2023-09-01	美商戴納立製藥公司	（Ｓ）－５－苄基－Ｎ－（５－甲基－４－側氧基－２，３，４，５－四氫吡啶並［３，２－ｂ］［１，４］氧氮呯－３－基）－４Ｈ－１，２，４－三唑－３－甲醯胺的晶型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2641280B1 (fr) *	1988-12-29	1994-01-21	Roussel Uclaf	Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments
GB9201180D0 (en) *	1992-01-21	1992-03-11	Glaxo Group Ltd	Chemical compounds
GB9307833D0 (en) *	1993-04-15	1993-06-02	Glaxo Inc	Modulators of cholecystokinin and gastrin

1995
- 1995-04-12 RU RU96121555/04A patent/RU2152939C1/ru active
- 1995-04-12 FI FI964045A patent/FI964045L/fi unknown
- 1995-04-12 SK SK1300-96A patent/SK281433B6/sk unknown
- 1995-04-12 ES ES95915540T patent/ES2135722T3/es not_active Expired - Lifetime
- 1995-04-12 AU AU22390/95A patent/AU697349B2/en not_active Ceased
- 1995-04-12 CZ CZ19962972A patent/CZ286764B6/cs not_active IP Right Cessation
- 1995-04-12 DK DK95915540T patent/DK0756602T3/da active
- 1995-04-12 MX MX9604765A patent/MX9604765A/es unknown
- 1995-04-12 DE DE69510545T patent/DE69510545T2/de not_active Expired - Fee Related
- 1995-04-12 KR KR1019960705732A patent/KR970702274A/ko not_active Ceased
- 1995-04-12 NZ NZ283929A patent/NZ283929A/en unknown
- 1995-04-12 CN CN95193582A patent/CN1176646A/zh active Pending
- 1995-04-12 EP EP95915540A patent/EP0756602B1/de not_active Expired - Lifetime
- 1995-04-12 BR BR9507381A patent/BR9507381A/pt unknown
- 1995-04-12 HU HU9602835A patent/HUT76135A/hu unknown
- 1995-04-12 PL PL95316870A patent/PL180026B1/pl unknown
- 1995-04-12 AT AT95915540T patent/ATE181737T1/de not_active IP Right Cessation
- 1995-04-12 JP JP7516406A patent/JPH09511223A/ja active Pending
- 1995-04-12 WO PCT/US1995/004163 patent/WO1995028419A1/en not_active Ceased
- 1995-04-12 TW TW084103539A patent/TW369529B/zh active
- 1995-04-12 CA CA002186900A patent/CA2186900A1/en not_active Abandoned
- 1995-04-13 IL IL11336595A patent/IL113365A/xx not_active IP Right Cessation
1996
- 1996-09-30 IS IS4367A patent/IS4367A/is unknown
- 1996-10-11 NO NO964348A patent/NO964348L/no not_active Application Discontinuation
1999
- 1999-09-28 GR GR990402437T patent/GR3031335T3/el unknown

Also Published As

Publication number	Publication date
DE69510545D1 (de)	1999-08-05
TW369529B (en)	1999-09-11
CA2186900A1 (en)	1995-10-26
GR3031335T3 (en)	1999-12-31
HU9602835D0 (en)	1996-12-30
IS4367A (is)	1996-09-30
WO1995028419A1 (en)	1995-10-26
SK130096A3 (en)	1997-08-06
KR970702274A (ko)	1997-05-13
ES2135722T3 (es)	1999-11-01
PL180026B1 (pl)	2000-12-29
CN1176646A (zh)	1998-03-18
CZ286764B6 (en)	2000-06-14
NO964348D0 (no)	1996-10-11
NO964348L (no)	1996-12-02
AU2239095A (en)	1995-11-10
HUT76135A (en)	1997-06-30
FI964045A0 (fi)	1996-10-09
PL316870A1 (en)	1997-02-17
DK0756602T3 (da)	2000-01-31
FI964045A7 (fi)	1996-10-09
EP0756602B1 (de)	1999-06-30
JPH09511223A (ja)	1997-11-11
CZ297296A3 (en)	1997-09-17
ATE181737T1 (de)	1999-07-15
BR9507381A (pt)	1997-09-23
IL113365A0 (en)	1995-07-31
RU2152939C1 (ru)	2000-07-20
FI964045L (fi)	1996-10-09
SK281433B6 (sk)	2001-03-12
EP0756602A1 (de)	1997-02-05
DE69510545T2 (de)	2000-01-13
AU697349B2 (en)	1998-10-01
NZ283929A (en)	1998-02-26
MX9604765A (es)	1998-05-31

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Legal Events

Date	Code	Title
2000-06-01	FF	Patent granted
2000-08-31	KB	Patent renewed
2001-07-24	KB	Patent renewed
2006-02-05	MM9K	Patent not in force due to non-payment of renewal fees