IL113747A - Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof - Google Patents

Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof

Info

Publication number: IL113747A
Authority: IL; Israel
Prior art keywords: water; compound; anhydrous; hydroxybutyl; formula
Prior art date: 1994-05-18

Application number

IL11374795A

Other languages

English (en)

Other versions

IL113747A0 (en

Original Assignee

Marion Merrell Dow Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-18

Filing date

1995-05-16

Publication date

2001-05-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL113747(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-05-16 Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc

1995-05-16 Priority to IL13491795A priority Critical patent/IL134917A/en

1995-08-31 Publication of IL113747A0 publication Critical patent/IL113747A0/xx

2000-03-07 Priority to IL13491700A priority patent/IL134917A0/xx

2001-05-20 Publication of IL113747A publication Critical patent/IL113747A/en

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Peptides Or Proteins (AREA)

IL11374795A 1994-05-18 1995-05-16 Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof IL113747A (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
IL13491795A IL134917A (en)	1994-05-18	1995-05-16	Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en)	1994-05-18	2000-03-07	Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24573194A	1994-05-18	1994-05-18
US41716195A	1995-04-11	1995-04-11

Publications (2)

Publication Number	Publication Date
IL113747A0 IL113747A0 (en)	1995-08-31
IL113747A true IL113747A (en)	2001-05-20

Family

ID=26937420

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
IL11374795A IL113747A (en)	1994-05-18	1995-05-16	Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof
IL13491795A IL134917A (en)	1994-05-18	1995-05-16	Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en)	1994-05-18	2000-03-07	Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
IL13491795A IL134917A (en)	1994-05-18	1995-05-16	Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en)	1994-05-18	2000-03-07	Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Country Status (17)

Country	Link
US (12)	US20010014741A1 (de)
EP (3)	EP1178041A1 (de)
JP (7)	JPH10500134A (de)
CN (3)	CN1623985A (de)
AT (1)	ATE220667T1 (de)
AU (1)	AU693892B2 (de)
CA (3)	CA2449419C (de)
DE (1)	DE69527429T2 (de)
DK (1)	DK0766668T3 (de)
ES (1)	ES2176329T3 (de)
FI (1)	FI964565A7 (de)
HU (1)	HU227676B1 (de)
IL (3)	IL113747A (de)
MX (1)	MX9605613A (de)
NO (1)	NO315319B1 (de)
PT (1)	PT766668E (de)
WO (1)	WO1995031437A1 (de)

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GB9400555D0 (en) *	1994-01-13	1994-03-09	Short Brothers Plc	Boundery layer control in aerodynamic low drag structures
CA2449419C (en) *	1994-05-18	2011-09-06	Aventis Pharmaceuticals Inc.	Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
EP0812195B1 (de)	1995-02-28	2002-10-30	Aventis Pharmaceuticals Inc.	Arzneizubereitungen für piperidinalkanolderivate
NZ501248A (en) *	1997-08-26	2001-06-29	Aventis Pharma Inc	Pharmaceutical composition for combination of piperidinoalkanol-decongestant
IN191492B (de) *	1999-05-25	2003-12-06	Ranbaxy Lab Ltd
US6613906B1 (en) *	2000-06-06	2003-09-02	Geneva Pharmaceuticals, Inc.	Crystal modification
CH695216A5 (de)	2001-02-23	2006-01-31	Cilag Ag	Verfahren zur Herstellung eines nicht hydratisierten Salzes eines Piperidinderivats und eine so erhältliche neue kristalline Form eines solchen Salzes.
US20030021849A1 (en) *	2001-04-09	2003-01-30	Ben-Zion Dolitzky	Polymorphs of fexofenadine hydrochloride
CZ20033019A3 (cs) *	2001-04-09	2004-07-14	Teva Pharmaceutical Industries Ltd.	Polymorfní formy chloridu fexofenadinu
US7700779B2 (en) *	2001-06-18	2010-04-20	Dr. Reddy's Laboratories Limited	Crystalline forms of fexofenadine and its hydrochloride
CA2450858C (en) *	2001-06-18	2009-04-07	Dr. Reddy's Laboratories Limited	Novel crystalline forms of 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-.alpha.,.alpha.-dimethylbenzene acetic acid and its hydrochloride
DE60225694T2 (de) *	2001-07-31	2008-06-26	Texcontor Etablissement	Neues polymorph von fexo-fenadin
US20030158227A1 (en) *	2001-11-08	2003-08-21	Barnaba Krochmal	Polymorphs of fexofenadine base
EP1474392A1 (de) *	2002-06-10	2004-11-10	Teva Pharmaceutical Industries Ltd.	Polymorphe form xvi von fexofenadin-hydrochlorid
JP3910907B2 (ja) *	2002-10-29	2007-04-25	新光電気工業株式会社	キャパシタ素子及びこの製造方法、半導体装置用基板、並びに半導体装置
CA2530193A1 (en) *	2003-07-03	2005-01-20	Teva Pharmaceutical Industries Ltd.	Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
GB0319935D0 (en)	2003-08-26	2003-09-24	Cipla Ltd	Polymorphs
KR20070007196A (ko) *	2004-04-26	2007-01-12	테바 파마슈티컬 인더스트리즈 리미티드	펙소페나딘 히드로클로라이드의 결정형 및 이의 제조 방법
ITMI20041143A1 (it) *	2004-06-08	2004-09-08	Dipharma Spa	Polimorfi di fexofenadina e procedimento per la loro preparazione
EP1616861A3 (de) *	2004-06-15	2006-02-08	Dipharma S.p.A.	Verfahren zur Herstellung von Keto-Verbindungen
ITMI20041568A1 (it) *	2004-07-30	2004-10-30	Dipharma Spa	"polimorfi di fexofenadina base"
JP2008514641A (ja) *	2004-09-28	2008-05-08	テバファーマシューティカルインダストリーズリミティド	結晶形フェキソフェナジン、およびその調製方法
DOP2006000274A (es) *	2005-12-14	2007-10-15	Sanofi Aventis Us Llc	Formulación de suspensión de fexofenadina
KR20090037930A (ko) *	2006-07-11	2009-04-16	뮤추얼 파마슈티컬 컴퍼니 아이엔씨.	조절 방출 제형
US20090076080A1 (en) *	2007-09-19	2009-03-19	Protia, Llc	Deuterium-enriched fexofenadine
EP2105134A1 (de)	2008-03-24	2009-09-30	Ranbaxy Laboratories Limited	Stabiles und amorphes Fexofenadin-Hydrochlorid
WO2010083360A2 (en) *	2009-01-16	2010-07-22	Mutual Pharmaceutical Company, Inc.	Controlled-release formulations
CN102595879B (zh)	2009-11-06	2014-08-06	巴斯夫欧洲公司	4-羟基苯甲酸和选定农药的结晶配合物
IT1400965B1 (it)	2010-06-15	2013-07-05	Dipharma Francis Srl	Polimorfi di fexofenadina
ES2403130B1 (es)	2010-06-15	2014-09-29	Chemelectiva S.R.L.	Forma polimórfica de clorhidrato de fexofenadina, compuestos intermedios y procedimiento para su preparación
US9420872B2 (en) *	2010-08-23	2016-08-23	Jason Bird	Apparatus and system for holding game-calling devices
JP2012087100A (ja) *	2010-10-21	2012-05-10	Sumitomo Chemical Co Ltd	形態ｉのフェキソフェナジン一塩酸塩の製造方法
CN104072402B (zh) *	2014-07-16	2016-08-17	昆山龙灯瑞迪制药有限公司	一种新结晶形式的盐酸非索非那定化合物及其制备方法

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US5576610A (en)	1994-07-05	1996-11-19	Motorola, Inc.	Method and apparatus for determining battery characteristics
IL134769A (en)	1995-02-28	2002-02-10	Aventis Pharma Inc	Pharmaceutical compositions of piperidinoalkanol compounds in solid unit dosage form
EP0812195B1 (de)	1995-02-28	2002-10-30	Aventis Pharmaceuticals Inc.	Arzneizubereitungen für piperidinalkanolderivate
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NZ501248A (en)	1997-08-26	2001-06-29	Aventis Pharma Inc	Pharmaceutical composition for combination of piperidinoalkanol-decongestant
US6214427B1 (en) *	1998-08-28	2001-04-10	General Electric Company	Method of making an electronic device having a single crystal substrate formed by solid state crystal conversion
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US20020177680A1 (en) *	2000-08-23	2002-11-28	Hubbell Jeffrey A.	Novel polymer compounds
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CZ20033019A3 (cs) *	2001-04-09	2004-07-14	Teva Pharmaceutical Industries Ltd.	Polymorfní formy chloridu fexofenadinu
US7700779B2 (en) *	2001-06-18	2010-04-20	Dr. Reddy's Laboratories Limited	Crystalline forms of fexofenadine and its hydrochloride
US20090211514A1 (en) *	2008-02-26	2009-08-27	Lehigh University	Single crystal conversion process

1995
- 1995-04-28 CA CA2449419A patent/CA2449419C/en not_active Expired - Lifetime
- 1995-04-28 FI FI964565A patent/FI964565A7/fi unknown
- 1995-04-28 CN CNA2003101007654A patent/CN1623985A/zh active Pending
- 1995-04-28 CA CA002189007A patent/CA2189007C/en not_active Expired - Lifetime
- 1995-04-28 AT AT95918278T patent/ATE220667T1/de active
- 1995-04-28 WO PCT/US1995/004942 patent/WO1995031437A1/en not_active Ceased
- 1995-04-28 DK DK95918278T patent/DK0766668T3/da active
- 1995-04-28 EP EP01124314A patent/EP1178041A1/de not_active Withdrawn
- 1995-04-28 PT PT95918278T patent/PT766668E/pt unknown
- 1995-04-28 AU AU24265/95A patent/AU693892B2/en not_active Expired
- 1995-04-28 ES ES95918278T patent/ES2176329T3/es not_active Expired - Lifetime
- 1995-04-28 HU HU9603167A patent/HU227676B1/hu unknown
- 1995-04-28 CN CN95193122A patent/CN1148849A/zh active Pending
- 1995-04-28 EP EP10180285A patent/EP2354125A1/de not_active Withdrawn
- 1995-04-28 CA CA2585705A patent/CA2585705C/en not_active Expired - Lifetime
- 1995-04-28 DE DE69527429T patent/DE69527429T2/de not_active Expired - Lifetime
- 1995-04-28 CN CN2006101031426A patent/CN1907967B/zh not_active Expired - Lifetime
- 1995-04-28 MX MX9605613A patent/MX9605613A/es unknown
- 1995-04-28 EP EP95918278A patent/EP0766668B1/de not_active Expired - Lifetime
- 1995-04-28 JP JP7529654A patent/JPH10500134A/ja not_active Withdrawn
- 1995-05-16 IL IL11374795A patent/IL113747A/en not_active IP Right Cessation
- 1995-05-16 IL IL13491795A patent/IL134917A/en not_active IP Right Cessation
1996
- 1996-11-15 NO NO19964859A patent/NO315319B1/no not_active IP Right Cessation
2000
- 2000-03-07 IL IL13491700A patent/IL134917A0/xx unknown
2001
- 2001-03-09 US US09/803,390 patent/US20010014741A1/en not_active Abandoned
- 2001-03-09 US US09/803,389 patent/US20010012896A1/en not_active Abandoned
- 2001-03-09 US US09/803,476 patent/US20010025106A1/en not_active Abandoned
2002
- 2002-03-01 JP JP2002055434A patent/JP4503909B2/ja not_active Expired - Lifetime
- 2002-03-01 JP JP2002055432A patent/JP4503907B2/ja not_active Expired - Lifetime
- 2002-03-01 JP JP2002055431A patent/JP2002308849A/ja active Pending
- 2002-03-01 JP JP2002055435A patent/JP2002316978A/ja not_active Withdrawn
- 2002-03-01 JP JP2002055433A patent/JP4503908B2/ja not_active Expired - Lifetime
- 2002-04-24 US US10/128,926 patent/US20020193600A1/en not_active Abandoned
- 2002-06-03 US US10/160,883 patent/US7135571B2/en not_active Expired - Fee Related
- 2002-06-03 US US10/162,011 patent/US7138524B2/en not_active Expired - Fee Related
- 2002-08-07 US US10/214,262 patent/US20030045721A1/en not_active Abandoned
2003
- 2003-03-10 US US10/386,812 patent/US20040014976A1/en not_active Abandoned
2006
- 2006-09-25 US US11/534,828 patent/US7666881B2/en not_active Expired - Fee Related
- 2006-09-25 US US11/534,839 patent/US7662835B2/en not_active Expired - Fee Related
2007
- 2007-10-30 US US11/978,669 patent/US20080167469A1/en not_active Abandoned
- 2007-10-30 US US11/978,670 patent/US20080167471A1/en not_active Abandoned
2010
- 2010-02-24 JP JP2010038971A patent/JP2010120969A/ja active Pending

Also Published As

Publication number	Publication date
CA2585705A1 (en)	1995-11-23
CN1148849A (zh)	1997-04-30
NO315319B1 (no)	2003-08-18
AU693892B2 (en)	1998-07-09
FI964565A0 (fi)	1996-11-14
US20040014976A1 (en)	2004-01-22
US20080167471A1 (en)	2008-07-10
IL134917A0 (en)	2001-05-20
CA2449419A1 (en)	1995-11-23
JP4503909B2 (ja)	2010-07-14
JP2002308850A (ja)	2002-10-23
PT766668E (pt)	2002-11-29
JP2002316978A (ja)	2002-10-31
MX9605613A (es)	1998-05-31
US7135571B2 (en)	2006-11-14
FI964565L (fi)	1996-11-14
NO964859L (no)	1996-11-15
HK1137742A1 (en)	2010-08-06
CN1907967B (zh)	2012-07-04
HU9603167D0 (en)	1997-01-28
HU227676B1 (en)	2011-11-28
DK0766668T3 (da)	2002-10-28
NO964859D0 (no)	1996-11-15
ATE220667T1 (de)	2002-08-15
JP2010120969A (ja)	2010-06-03
IL134917A (en)	2001-07-24
DE69527429D1 (de)	2002-08-22
EP1178041A1 (de)	2002-02-06
JP4503908B2 (ja)	2010-07-14
US7666881B2 (en)	2010-02-23
US20010025106A1 (en)	2001-09-27
US20070021462A1 (en)	2007-01-25
EP0766668A1 (de)	1997-04-09
US20030045721A1 (en)	2003-03-06
AU2426595A (en)	1995-12-05
CN1907967A (zh)	2007-02-07
US20010014741A1 (en)	2001-08-16
US20070021461A1 (en)	2007-01-25
JP2002255935A (ja)	2002-09-11
JP4503907B2 (ja)	2010-07-14
US20020193601A1 (en)	2002-12-19
ES2176329T3 (es)	2002-12-01
CA2585705C (en)	2012-04-17
CA2189007C (en)	2004-03-02
US20020193603A1 (en)	2002-12-19
CA2449419C (en)	2011-09-06
HUT76134A (en)	1997-06-30
FI964565A7 (fi)	1996-11-14
CA2189007A1 (en)	1995-11-23
US20020193600A1 (en)	2002-12-19
DE69527429T2 (de)	2003-03-20
US20010012896A1 (en)	2001-08-09
US7662835B2 (en)	2010-02-16
EP0766668B1 (de)	2002-07-17
IL113747A0 (en)	1995-08-31
HK1098467A1 (en)	2007-07-20
CN1623985A (zh)	2005-06-08
JPH10500134A (ja)	1998-01-06
US20080167469A1 (en)	2008-07-10
US7138524B2 (en)	2006-11-21
EP2354125A1 (de)	2011-08-10
JP2002308849A (ja)	2002-10-23
JP2002255936A (ja)	2002-09-11
WO1995031437A1 (en)	1995-11-23

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