ATE220667T1 - Verfahren zur herstellung von wasserfreien und hydrat-formen von antihistaminischen piperinderivaten, polymerphe und pseudomorphe davon - Google Patents

Verfahren zur herstellung von wasserfreien und hydrat-formen von antihistaminischen piperinderivaten, polymerphe und pseudomorphe davon

Info

Publication number
ATE220667T1
ATE220667T1 AT95918278T AT95918278T ATE220667T1 AT E220667 T1 ATE220667 T1 AT E220667T1 AT 95918278 T AT95918278 T AT 95918278T AT 95918278 T AT95918278 T AT 95918278T AT E220667 T1 ATE220667 T1 AT E220667T1
Authority
AT
Austria
Prior art keywords
pseudomorphos
polymerphs
anthistaminic
hydrate forms
producing anhydrous
Prior art date
Application number
AT95918278T
Other languages
English (en)
Inventor
Daniel R Henton
Frederick J Mccarty
Susan I Tripp
Jill E Dewitt
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE220667(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of ATE220667T1 publication Critical patent/ATE220667T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT95918278T 1994-05-18 1995-04-28 Verfahren zur herstellung von wasserfreien und hydrat-formen von antihistaminischen piperinderivaten, polymerphe und pseudomorphe davon ATE220667T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24573194A 1994-05-18 1994-05-18
US41716195A 1995-04-11 1995-04-11
PCT/US1995/004942 WO1995031437A1 (en) 1994-05-18 1995-04-28 Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof

Publications (1)

Publication Number Publication Date
ATE220667T1 true ATE220667T1 (de) 2002-08-15

Family

ID=26937420

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95918278T ATE220667T1 (de) 1994-05-18 1995-04-28 Verfahren zur herstellung von wasserfreien und hydrat-formen von antihistaminischen piperinderivaten, polymerphe und pseudomorphe davon

Country Status (17)

Country Link
US (12) US20010012896A1 (de)
EP (3) EP2354125A1 (de)
JP (7) JPH10500134A (de)
CN (3) CN1623985A (de)
AT (1) ATE220667T1 (de)
AU (1) AU693892B2 (de)
CA (3) CA2189007C (de)
DE (1) DE69527429T2 (de)
DK (1) DK0766668T3 (de)
ES (1) ES2176329T3 (de)
FI (1) FI964565A0 (de)
HU (1) HU227676B1 (de)
IL (3) IL134917A (de)
MX (1) MX9605613A (de)
NO (1) NO315319B1 (de)
PT (1) PT766668E (de)
WO (1) WO1995031437A1 (de)

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DE69624559T2 (de) 1995-02-28 2003-07-10 Aventis Pharmaceuticals Inc., Bridgewater Arzneizubereitungen für piperidinalkanolderivate
EP0998272B1 (de) * 1997-08-26 2003-05-02 Aventis Pharmaceuticals Inc. Arzneimittel für die kombination piperidinoalkanol-dekongestivum
IN191492B (de) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
US6613906B1 (en) 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
CH695216A5 (de) 2001-02-23 2006-01-31 Cilag Ag Verfahren zur Herstellung eines nicht hydratisierten Salzes eines Piperidinderivats und eine so erhältliche neue kristalline Form eines solchen Salzes.
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
MXPA03009259A (es) * 2001-04-09 2004-06-03 Teva Pharma Polimorfos de clorhidrato de fexofenadina.
US7700779B2 (en) 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
BR0117054A (pt) * 2001-06-18 2004-07-27 Reddys Lab Ltd Dr Formas cristalinas do ácido 4-[4-[4-hidroxidifenilmetil)-1-piperidinil]-1-hidroxibuti l]-alfa, alfa-dimetilbenzeno acético e seu cloridrato
ATE389405T1 (de) * 2001-07-31 2008-04-15 Texcontor Ets Fexofenadine hydrochlorid polymorph
US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
WO2003104197A1 (en) * 2002-06-10 2003-12-18 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
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GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
WO2005102999A2 (en) * 2004-04-26 2005-11-03 Teva Pharmaceutical Industries Ltd. Crystalline forms of fexofenadine hydrochloride and processes for their preparation
ITMI20041143A1 (it) 2004-06-08 2004-09-08 Dipharma Spa Polimorfi di fexofenadina e procedimento per la loro preparazione
EP1616861A3 (de) * 2004-06-15 2006-02-08 Dipharma S.p.A. Verfahren zur Herstellung von Keto-Verbindungen
ITMI20041568A1 (it) * 2004-07-30 2004-10-30 Dipharma Spa "polimorfi di fexofenadina base"
EP1685106A2 (de) * 2004-09-28 2006-08-02 Teva Pharmaceutical Industries, Inc. Fexofendadin-kristallform und verfahren zu deren herstellung
DOP2006000274A (es) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
CA2658170A1 (en) * 2006-07-11 2008-01-17 Mutual Pharmaceutical Company, Inc. Controlled-release formulations
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
US20090306135A1 (en) 2008-03-24 2009-12-10 Mukesh Kumar Sharma Stable amorphous fexofenadine hydrochloride
WO2010083360A2 (en) * 2009-01-16 2010-07-22 Mutual Pharmaceutical Company, Inc. Controlled-release formulations
WO2011054741A2 (en) 2009-11-06 2011-05-12 Basf Se Crystalline complexes of 4-hydroxy benzoic acid and selected pesticides
WO2011158262A1 (en) 2010-06-15 2011-12-22 Chemelectiva S.R.L. Polymorphic form of fexofenadine hydrochloride, intermediates and process for its preparation
IT1400965B1 (it) 2010-06-15 2013-07-05 Dipharma Francis Srl Polimorfi di fexofenadina
US9420872B2 (en) * 2010-08-23 2016-08-23 Jason Bird Apparatus and system for holding game-calling devices
JP2012087100A (ja) * 2010-10-21 2012-05-10 Sumitomo Chemical Co Ltd 形態ｉのフェキソフェナジン一塩酸塩の製造方法
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Also Published As

Publication number Publication date
JP2002316978A (ja) 2002-10-31
US20080167471A1 (en) 2008-07-10
HUT76134A (en) 1997-06-30
CN1623985A (zh) 2005-06-08
CN1148849A (zh) 1997-04-30
US20010014741A1 (en) 2001-08-16
US7138524B2 (en) 2006-11-21
US7666881B2 (en) 2010-02-23
JP2010120969A (ja) 2010-06-03
DE69527429T2 (de) 2003-03-20
US20020193603A1 (en) 2002-12-19
EP0766668B1 (de) 2002-07-17
PT766668E (pt) 2002-11-29
FI964565L (fi) 1996-11-14
US20040014976A1 (en) 2004-01-22
DE69527429D1 (de) 2002-08-22
EP1178041A1 (de) 2002-02-06
EP2354125A1 (de) 2011-08-10
JP2002308849A (ja) 2002-10-23
CA2189007C (en) 2004-03-02
IL134917A0 (en) 2001-05-20
JP4503907B2 (ja) 2010-07-14
JP4503909B2 (ja) 2010-07-14
HK1098467A1 (en) 2007-07-20
NO964859L (no) 1996-11-15
US20080167469A1 (en) 2008-07-10
ES2176329T3 (es) 2002-12-01
JP2002255936A (ja) 2002-09-11
EP0766668A1 (de) 1997-04-09
CA2585705C (en) 2012-04-17
CA2189007A1 (en) 1995-11-23
US7662835B2 (en) 2010-02-16
CA2585705A1 (en) 1995-11-23
AU693892B2 (en) 1998-07-09
US20010012896A1 (en) 2001-08-09
JP4503908B2 (ja) 2010-07-14
US20010025106A1 (en) 2001-09-27
US20070021461A1 (en) 2007-01-25
IL113747A (en) 2001-05-20
US20030045721A1 (en) 2003-03-06
HK1137742A1 (en) 2010-08-06
CA2449419A1 (en) 1995-11-23
CN1907967A (zh) 2007-02-07
FI964565A7 (fi) 1996-11-14
US20070021462A1 (en) 2007-01-25
JPH10500134A (ja) 1998-01-06
JP2002308850A (ja) 2002-10-23
IL113747A0 (en) 1995-08-31
NO964859D0 (no) 1996-11-15
AU2426595A (en) 1995-12-05
MX9605613A (es) 1998-05-31
HU9603167D0 (en) 1997-01-28
US7135571B2 (en) 2006-11-14
DK0766668T3 (da) 2002-10-28
JP2002255935A (ja) 2002-09-11
IL134917A (en) 2001-07-24
WO1995031437A1 (en) 1995-11-23
CN1907967B (zh) 2012-07-04
CA2449419C (en) 2011-09-06
FI964565A0 (fi) 1996-11-14
US20020193600A1 (en) 2002-12-19
NO315319B1 (no) 2003-08-18
US20020193601A1 (en) 2002-12-19
HU227676B1 (en) 2011-11-28

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