IL114765A - Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their uses - Google Patents

Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their uses

Info

Publication number
IL114765A
IL114765A IL11476595A IL11476595A IL114765A IL 114765 A IL114765 A IL 114765A IL 11476595 A IL11476595 A IL 11476595A IL 11476595 A IL11476595 A IL 11476595A IL 114765 A IL114765 A IL 114765A
Authority
IL
Israel
Prior art keywords
ligand specific
alpha
rar
rxrs
compositions based
Prior art date
Application number
IL11476595A
Other languages
English (en)
Other versions
IL114765A0 (en
Original Assignee
Galderma Rech Dermatologique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Rech Dermatologique filed Critical Galderma Rech Dermatologique
Publication of IL114765A0 publication Critical patent/IL114765A0/xx
Publication of IL114765A publication Critical patent/IL114765A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Catalysts (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11476595A 1994-07-27 1995-07-27 Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their uses IL114765A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9409307A FR2722985B1 (fr) 1994-07-27 1994-07-27 Nouvelles compositions a base d'un melange synergetique entre au moins un ligand specifique des rxrs et au moins un ligand specifique de rar-x ou de vdr, et leurs utilisations

Publications (2)

Publication Number Publication Date
IL114765A0 IL114765A0 (en) 1995-11-27
IL114765A true IL114765A (en) 2000-06-01

Family

ID=9465802

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11476595A IL114765A (en) 1994-07-27 1995-07-27 Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their uses

Country Status (19)

Country Link
US (1) US5767148A (de)
EP (1) EP0694301B1 (de)
JP (1) JP2783521B2 (de)
KR (1) KR0168727B1 (de)
AT (1) ATE145134T1 (de)
AU (1) AU674479B2 (de)
BR (1) BR9502338A (de)
CA (1) CA2154730C (de)
DE (1) DE69500085T2 (de)
ES (1) ES2098164T3 (de)
FI (1) FI953567A7 (de)
FR (1) FR2722985B1 (de)
HU (1) HUT73793A (de)
IL (1) IL114765A (de)
NO (1) NO952944L (de)
NZ (1) NZ272527A (de)
PL (1) PL181061B1 (de)
RU (1) RU2120304C1 (de)
ZA (1) ZA955537B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735370B1 (fr) * 1995-06-19 1997-07-18 Cird Galderma Procede pour identifier des composes agonistes des recepteurs rxrs
FR2735367B1 (fr) * 1995-06-19 1997-07-18 Cird Galderma Utilisation de ligands specifiques des recepteurs rxrs
FR2739777B1 (fr) * 1995-10-11 1997-11-14 Cird Galderma Ligand antagoniste rar-gamma ou agoniste rar-alpha en tant qu'inhibiteur d'apoptose
US5965606A (en) * 1995-12-29 1999-10-12 Allergan Sales, Inc. Methods of treatment with compounds having RAR.sub.α receptor specific or selective activity
FR2753091B1 (fr) * 1996-09-09 2001-03-16 Oreal Utilisation d'un agoniste des recepteurs des retinoides de type rxr pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
WO1998046076A1 (en) * 1997-04-11 1998-10-22 Sidney Kimmel Cancer Center Retinoid related molecules for the inhibition of endothelin-1 overproduction in disease
EP1003493A4 (de) * 1997-07-29 2002-03-27 Bristol Myers Squibb Co Verwendung von selektion rxr agonisten zur vorbeugung chirurgischen adhäsionen
FR2779720B1 (fr) * 1998-06-12 2002-08-16 Galderma Rech Dermatologique Nouveaux composes diarylselenures et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetologie
US6436993B1 (en) * 1999-07-13 2002-08-20 The Salk Institute For Biological Studies Use of RAR antagonists as modulators of hormone mediated processes
US6904229B1 (en) * 1999-08-20 2005-06-07 Canon Kabushiki Kaisha Apparatus for recording signals on disk recording medium
JP4118675B2 (ja) * 2000-10-02 2008-07-16 エフ．ホフマン−ラ ロシュ アーゲー 気腫治療用新規レチノイド
RU2257204C2 (ru) * 2003-08-12 2005-07-27 Открытое Акционерное Общество "Фармакон" (ОАО "Фармакон") Противогрибковая гелевая фармацевтическая композиция и способ ее получения
CN100388532C (zh) * 2005-09-28 2008-05-14 浙江工业大学 一种锂二次电池的隔膜添加剂及锂二次电池隔膜

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3301328A1 (de) * 1982-02-01 1983-08-11 The Upjohn Co., 49001 Kalamazoo, Mich. Arzneimittel zur einleitenden bekaempfung von akuter oder chronischer, myelogener leukaemie
CA2114936C (en) * 1991-08-23 2004-02-10 Ronald M. Evans Use of selective ligands for treatment of disease states responsive to steroid or steroid-like hormones
BR9306284A (pt) * 1992-04-22 1998-01-13 Ligand Pharm Inc Compostos tendo seletividade pra receptores de retinóides x

Also Published As

Publication number Publication date
JPH0859511A (ja) 1996-03-05
FR2722985A1 (fr) 1996-02-02
US5767148A (en) 1998-06-16
FR2722985B1 (fr) 1996-09-13
ZA955537B (en) 1996-02-16
KR0168727B1 (ko) 1999-01-15
NO952944D0 (no) 1995-07-25
PL309772A1 (en) 1996-02-05
NZ272527A (en) 1997-01-29
ATE145134T1 (de) 1996-11-15
IL114765A0 (en) 1995-11-27
ES2098164T3 (es) 1997-04-16
AU674479B2 (en) 1996-12-19
FI953567L (fi) 1996-01-28
RU2120304C1 (ru) 1998-10-20
EP0694301B1 (de) 1996-11-13
CA2154730A1 (fr) 1996-01-28
CA2154730C (fr) 2000-02-15
NO952944L (no) 1996-01-29
DE69500085D1 (de) 1996-12-19
PL181061B1 (pl) 2001-05-31
HU9502241D0 (en) 1995-09-28
FI953567A0 (fi) 1995-07-26
BR9502338A (pt) 1996-02-27
DE69500085T2 (de) 1997-03-06
EP0694301A1 (de) 1996-01-31
KR960003721A (ko) 1996-02-23
AU2327995A (en) 1996-02-08
JP2783521B2 (ja) 1998-08-06
FI953567A7 (fi) 1996-01-28
HUT73793A (en) 1996-09-30

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees