IL115300A - POLYSUBSTITUTED [1,2,4] TRIAZOLO [4,3-a] QUINOXALIN-4(5H)-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

POLYSUBSTITUTED [1,2,4] TRIAZOLO [4,3-a] QUINOXALIN-4(5H)-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IL115300A
IL115300A IL11530095A IL11530095A IL115300A IL 115300 A IL115300 A IL 115300A IL 11530095 A IL11530095 A IL 11530095A IL 11530095 A IL11530095 A IL 11530095A IL 115300 A IL115300 A IL 115300A
Authority
IL
Israel
Prior art keywords
compound
formula
defined above
alkoxy
triazolo
Prior art date
Application number
IL11530095A
Other languages
English (en)
Other versions
IL115300A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL115300A0 publication Critical patent/IL115300A0/xx
Publication of IL115300A publication Critical patent/IL115300A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL11530095A 1994-09-16 1995-09-14 POLYSUBSTITUTED [1,2,4] TRIAZOLO [4,3-a] QUINOXALIN-4(5H)-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL115300A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK106594 1994-09-16

Publications (2)

Publication Number Publication Date
IL115300A0 IL115300A0 (en) 1995-12-31
IL115300A true IL115300A (en) 2001-06-14

Family

ID=8100599

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11530095A IL115300A (en) 1994-09-16 1995-09-14 POLYSUBSTITUTED [1,2,4] TRIAZOLO [4,3-a] QUINOXALIN-4(5H)-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (23)

Country Link
US (1) US6001832A (de)
EP (1) EP0783504B1 (de)
JP (1) JPH10505601A (de)
CN (1) CN1083842C (de)
AT (1) ATE190616T1 (de)
AU (1) AU706737B2 (de)
CA (1) CA2200055A1 (de)
CZ (1) CZ285248B6 (de)
DE (1) DE69515680T2 (de)
DK (1) DK0783504T3 (de)
ES (1) ES2146769T3 (de)
FI (1) FI971075L (de)
GR (1) GR3033642T3 (de)
HU (1) HUT76810A (de)
IL (1) IL115300A (de)
NO (1) NO308796B1 (de)
NZ (1) NZ292107A (de)
PL (1) PL319176A1 (de)
PT (1) PT783504E (de)
RU (1) RU2149162C1 (de)
SK (1) SK282635B6 (de)
WO (1) WO1996008492A1 (de)
ZA (1) ZA957795B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9651198A (en) 1997-11-11 1999-05-31 Ono Pharmaceutical Co. Ltd. Fused pyrazine compounds
WO2008072779A1 (ja) * 2006-12-13 2008-06-19 Aska Pharmaceutical Co., Ltd. キノキサリン誘導体
BRPI1009287A2 (pt) 2009-03-05 2019-09-24 Astellas Pharma Inc composto de quinoxalina
WO2012033101A1 (ja) 2010-09-07 2012-03-15 アステラス製薬株式会社 キノキサリン化合物
US9181264B2 (en) * 2010-09-16 2015-11-10 Hutchison Medipharma Limited Fused heteroaryls and their uses

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
DD228811A1 (de) * 1984-04-17 1985-10-23 Hydrierwerk Rodleben Veb Verfahren zur herstellung von neuen triazolopyrimidinen
GB8512163D0 (en) * 1985-05-14 1985-06-19 Fujisawa Pharmaceutical Co Oxothiazolidine compound
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
WO1993020077A1 (fr) * 1992-04-03 1993-10-14 Yamanouchi Pharmaceutical Co., Ltd. Derive de quinoxalinone fondue et composition pharmaceutique le contenant
DK31093D0 (de) * 1993-03-19 1993-03-19 Novo Nordisk As
KR100304177B1 (ko) * 1993-05-06 2001-11-22 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 (1,2,4)트리아졸로(4,3-a)퀴녹살린화합물,이의제조방법및이를함유하는약제학적조성물_

Also Published As

Publication number Publication date
EP0783504B1 (de) 2000-03-15
RU2149162C1 (ru) 2000-05-20
CZ75497A3 (en) 1997-08-13
AU3380795A (en) 1996-03-29
SK282635B6 (sk) 2002-10-08
CA2200055A1 (en) 1996-03-21
CN1193974A (zh) 1998-09-23
ZA957795B (en) 1996-05-14
ES2146769T3 (es) 2000-08-16
CN1083842C (zh) 2002-05-01
FI971075A7 (fi) 1997-05-13
DE69515680D1 (de) 2000-04-20
JPH10505601A (ja) 1998-06-02
WO1996008492A1 (en) 1996-03-21
NO308796B1 (no) 2000-10-30
DE69515680T2 (de) 2000-10-19
AU706737B2 (en) 1999-06-24
SK33597A3 (en) 1998-02-04
ATE190616T1 (de) 2000-04-15
NZ292107A (en) 1999-02-25
CZ285248B6 (cs) 1999-06-16
FI971075L (fi) 1997-05-13
NO971186D0 (no) 1997-03-14
EP0783504A1 (de) 1997-07-16
US6001832A (en) 1999-12-14
HUT76810A (en) 1997-11-28
PT783504E (pt) 2000-08-31
IL115300A0 (en) 1995-12-31
PL319176A1 (en) 1997-08-04
DK0783504T3 (da) 2000-08-14
FI971075A0 (fi) 1997-03-14
NO971186L (no) 1997-05-15
GR3033642T3 (en) 2000-10-31

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed