IL116617A - Monoclonal antibody 4g9, 2g6 or bh4, or an antigen binding fragment thereof reactive with in vivo produced advanced glycosylation endproducts - Google Patents

Monoclonal antibody 4g9, 2g6 or bh4, or an antigen binding fragment thereof reactive with in vivo produced advanced glycosylation endproducts

Info

Publication number
IL116617A
IL116617A IL11661795A IL11661795A IL116617A IL 116617 A IL116617 A IL 116617A IL 11661795 A IL11661795 A IL 11661795A IL 11661795 A IL11661795 A IL 11661795A IL 116617 A IL116617 A IL 116617A
Authority
IL
Israel
Prior art keywords
age
monoclonal antibody
ages
antibody
binding fragment
Prior art date
Application number
IL11661795A
Other languages
English (en)
Other versions
IL116617A0 (en
Original Assignee
Alteon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/367,507 external-priority patent/US5744318A/en
Application filed by Alteon Inc filed Critical Alteon Inc
Publication of IL116617A0 publication Critical patent/IL116617A0/xx
Publication of IL116617A publication Critical patent/IL116617A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL11661795A 1994-12-30 1995-12-29 Monoclonal antibody 4g9, 2g6 or bh4, or an antigen binding fragment thereof reactive with in vivo produced advanced glycosylation endproducts IL116617A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/367,507 US5744318A (en) 1994-12-30 1994-12-30 Monoclonal antibody for the detection of advanced glycosylation endproducts in biological samples
US08/483,186 US5698197A (en) 1994-12-30 1995-06-07 Monoclonal antibody specific for advanced glycosylation endproducts in biological samples
US08/581,724 US5892000A (en) 1994-12-30 1995-12-29 Monoclonal antibodies specific for advanced glycosylation endproducts in biological samples

Publications (2)

Publication Number Publication Date
IL116617A0 IL116617A0 (en) 1996-09-12
IL116617A true IL116617A (en) 2001-09-13

Family

ID=27408819

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11661795A IL116617A (en) 1994-12-30 1995-12-29 Monoclonal antibody 4g9, 2g6 or bh4, or an antigen binding fragment thereof reactive with in vivo produced advanced glycosylation endproducts

Country Status (10)

Country Link
US (2) US5892000A (de)
EP (1) EP0801658B1 (de)
JP (1) JP2002514888A (de)
AT (1) ATE245169T1 (de)
AU (1) AU693992B2 (de)
CA (1) CA2208411A1 (de)
DE (1) DE69531311T2 (de)
ES (1) ES2203651T3 (de)
IL (1) IL116617A (de)
WO (1) WO1996020958A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1431397A (en) * 1995-12-29 1997-07-28 Alteon Inc. 6-(n-carboxymethylamino)caproate, salts thereof and methods of use therefor
US7071298B2 (en) * 1997-02-05 2006-07-04 Fox Chase Cancer Center Compounds and methods for treating glycogen storage disease and other pathological conditions resulting from formation of age-proteins
JPH11258238A (ja) * 1998-03-10 1999-09-24 Tokuyama Corp 免疫学的凝集測定用試薬キット
JP2002517224A (ja) * 1998-06-09 2002-06-18 アルテオン インコーポレーテッド 生体サンプル内におけるグアニジノ基由来進行グリコシル化最終生成物に特異的なモノクローナル抗体
FR2798735B1 (fr) * 1999-09-17 2001-11-23 Serobiologiques Lab Sa Procede d'evaluation et de suivi du vieillissement tissulaire
HUE031902T2 (en) * 2008-05-23 2017-08-28 Siwa Corp Procedures and Preparations to Promote Regeneration
US9649376B2 (en) 2010-09-27 2017-05-16 Siwa Corporation Selective removal of age-modified cells for treatment of atherosclerosis
US8721571B2 (en) 2010-11-22 2014-05-13 Siwa Corporation Selective removal of cells having accumulated agents
CA2961603C (en) 2014-09-19 2021-07-13 Siwa Corporation Anti-age antibodies for treating inflammation and auto-immune disorders
US10358502B2 (en) 2014-12-18 2019-07-23 Siwa Corporation Product and method for treating sarcopenia
US9993535B2 (en) 2014-12-18 2018-06-12 Siwa Corporation Method and composition for treating sarcopenia
KR102786111B1 (ko) 2016-02-19 2025-03-26 시와 코퍼레이션 고급 당화 최종 산물(age)에 대한 항체를 사용하여 암을 치료하고, 전이성 암 세포를 사멸시키고, 암 전이를 예방하기 위한 방법 및 조성물
AU2017250301A1 (en) 2016-04-15 2018-11-15 Siwa Corporation Anti-age antibodies for treating neurodegenerative disorders
WO2017222535A1 (en) 2016-06-23 2017-12-28 Siwa Corporation Vaccines for use in treating various diseases and disorders
US10858449B1 (en) 2017-01-06 2020-12-08 Siwa Corporation Methods and compositions for treating osteoarthritis
US10995151B1 (en) 2017-01-06 2021-05-04 Siwa Corporation Methods and compositions for treating disease-related cachexia
US10961321B1 (en) 2017-01-06 2021-03-30 Siwa Corporation Methods and compositions for treating pain associated with inflammation
US10925937B1 (en) 2017-01-06 2021-02-23 Siwa Corporation Vaccines for use in treating juvenile disorders associated with inflammation
EP3609923A1 (de) 2017-04-13 2020-02-19 Siwa Corporation Humanisierter monoklonaler advanced-glycation-endproduct-antikörper
US11518801B1 (en) 2017-12-22 2022-12-06 Siwa Corporation Methods and compositions for treating diabetes and diabetic complications
CN110208543A (zh) * 2019-06-06 2019-09-06 威海威高生物科技有限公司 血管内皮生长因子检测试剂盒及其使用方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869534A (en) * 1992-05-21 1999-02-09 The Picower Institute For Medical Research Glycosylation of lipids and lipid-containing particles, and diagnostic and therapeutic methods and materials derived therefrom
US5624804A (en) * 1991-12-20 1997-04-29 The Rockefeller University Immunochemical detection of In vivo advanced glycosylation end products

Also Published As

Publication number Publication date
EP0801658A1 (de) 1997-10-22
DE69531311D1 (de) 2003-08-21
CA2208411A1 (en) 1996-07-11
AU4648396A (en) 1996-07-24
US5892000A (en) 1999-04-06
AU693992B2 (en) 1998-07-09
USRE39138E1 (en) 2006-06-20
WO1996020958A1 (en) 1996-07-11
EP0801658B1 (de) 2003-07-16
JP2002514888A (ja) 2002-05-21
DE69531311T2 (de) 2004-04-22
IL116617A0 (en) 1996-09-12
ATE245169T1 (de) 2003-08-15
ES2203651T3 (es) 2004-04-16

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees