IL117175A - Osteoclastogenesis inhibitory factor protein - Google Patents
Osteoclastogenesis inhibitory factor proteinInfo
- Publication number
- IL117175A IL117175A IL11717596A IL11717596A IL117175A IL 117175 A IL117175 A IL 117175A IL 11717596 A IL11717596 A IL 11717596A IL 11717596 A IL11717596 A IL 11717596A IL 117175 A IL117175 A IL 117175A
- Authority
- IL
- Israel
- Prior art keywords
- protein
- inhibitory factor
- antibodies
- factor protein
- produced
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5497795 | 1995-02-20 | ||
| JP20750895 | 1995-07-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117175A0 IL117175A0 (en) | 1996-06-18 |
| IL117175A true IL117175A (en) | 2005-11-20 |
Family
ID=26395808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11717596A IL117175A (en) | 1995-02-20 | 1996-02-19 | Osteoclastogenesis inhibitory factor protein |
Country Status (20)
| Country | Link |
|---|---|
| US (9) | US7125686B1 (de) |
| EP (2) | EP1528103B1 (de) |
| JP (1) | JP3502102B2 (de) |
| KR (1) | KR100381788B1 (de) |
| CN (1) | CN1218961C (de) |
| AT (2) | ATE391178T1 (de) |
| AU (1) | AU702557C (de) |
| CA (1) | CA2213469A1 (de) |
| DE (2) | DE69637486D1 (de) |
| ES (1) | ES2227579T3 (de) |
| FI (1) | FI973402A7 (de) |
| HU (1) | HU224570B1 (de) |
| IL (1) | IL117175A (de) |
| MX (1) | MX9706341A (de) |
| NO (1) | NO318898B1 (de) |
| NZ (1) | NZ301362A (de) |
| PT (1) | PT816380E (de) |
| RU (2) | RU2194714C2 (de) |
| TW (1) | TW538049B (de) |
| WO (1) | WO1996026217A1 (de) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7094564B1 (en) | 1995-03-15 | 2006-08-22 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor |
| AU2159995A (en) * | 1995-03-15 | 1996-10-02 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor |
| US8110659B1 (en) | 1995-03-15 | 2012-02-07 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like genes |
| US7078493B1 (en) | 1995-03-15 | 2006-07-18 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like genes |
| US6369027B1 (en) | 1995-12-22 | 2002-04-09 | Amgen Inc. | Osteoprotegerin |
| US7632922B1 (en) * | 1995-12-22 | 2009-12-15 | Amgen, Inc. | Osteoprotegerin |
| JPH1057071A (ja) * | 1996-08-19 | 1998-03-03 | Snow Brand Milk Prod Co Ltd | 新規dna及びそれを用いた蛋白質の製造方法 |
| AU7364696A (en) * | 1996-09-18 | 1998-04-14 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like genes |
| PT1114864E (pt) * | 1996-12-13 | 2008-10-08 | Schering Corp | Antigénios de superfície de células de mamífero, reagentes relacionados |
| US6271349B1 (en) | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
| DE69740107D1 (de) * | 1996-12-23 | 2011-03-10 | Immunex Corp | Rezeptor aktivator von nf-kappa b, rezeptor is mitglied der tnf rezeptor superfamilie |
| ES2263204T5 (es) | 1997-04-15 | 2013-10-14 | Daiichi Sankyo Company, Limited | Nueva proteína y proceso para producir la misma |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| ES2284203T5 (es) | 1997-04-16 | 2016-03-11 | Amgen Inc. | Proteínas de unión a osteoprotegerina y sus receptores |
| JP2002514078A (ja) * | 1997-04-18 | 2002-05-14 | ミレニアム ファーマシューティカルズ インク. | Fthma−070関連蛋白質ファミリーおよびt85関連蛋白質ファミリーの新規分子ならびにそれらの使用 |
| CA2288351A1 (en) * | 1997-05-01 | 1998-11-05 | Amgen Inc. | Chimeric opg polypeptides |
| US6346388B1 (en) | 1997-08-13 | 2002-02-12 | Smithkline Beecham Corporation | Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2 |
| JP4268684B2 (ja) * | 1997-09-24 | 2009-05-27 | 第一三共株式会社 | 骨代謝異常症の診断方法 |
| US6297022B1 (en) | 1997-10-08 | 2001-10-02 | Smithkline Beecham Corporation | Method of identifying agonists and antagonists for tumor necrosis related receptor TR1 |
| US6087555A (en) * | 1997-10-15 | 2000-07-11 | Amgen Inc. | Mice lacking expression of osteoprotegerin |
| JPH11155420A (ja) * | 1997-12-02 | 1999-06-15 | Snow Brand Milk Prod Co Ltd | トランスジェニック動物 |
| AU762574B2 (en) | 1998-05-14 | 2003-06-26 | Immunex Corporation | Method of inhibiting osteoclast activity |
| WO2000021554A1 (en) * | 1998-10-09 | 2000-04-20 | Sankyo Company, Limited | Preventives or remedies for cachexia |
| HUP0104126A3 (en) * | 1998-10-28 | 2004-07-28 | Sankyo Company Ltd Chuo Ku | Remedies for bone metabolic errors |
| AUPQ167599A0 (en) * | 1999-07-19 | 1999-08-12 | St. Vincent's Institute Of Medical Research | Inhibitor of osteoclast precursor formation |
| AU7720600A (en) * | 1999-09-27 | 2001-04-30 | Eli Lilly And Company | Osteoprotegerin regulatory region |
| JP2001103964A (ja) * | 1999-10-05 | 2001-04-17 | Teijin Ltd | 破骨細胞形成抑制方法または骨吸収抑制方法 |
| WO2002062990A1 (fr) * | 2001-02-07 | 2002-08-15 | Sankyo Company, Limited | Anticorps et utilisation de cet anticorps |
| WO2002064782A2 (en) * | 2001-02-09 | 2002-08-22 | Maxygen Holdings Ltd. | Rank ligand-binding polypeptides |
| CN1238379C (zh) * | 2001-03-21 | 2006-01-25 | 中国科学院上海生命科学研究院 | 新的破骨细胞形成抑制因子、其编码序列及用途 |
| EP1377610A2 (de) * | 2001-04-03 | 2004-01-07 | Société des Produits Nestlé S.A. | Osteoprotegerin in milch |
| US7064189B2 (en) | 2001-05-25 | 2006-06-20 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
| EP2295081B1 (de) | 2001-06-26 | 2018-10-31 | Amgen Inc. | Antikörper gegen OPGL |
| EP1270015A3 (de) * | 2001-06-29 | 2004-02-25 | Sankyo Company Limited | Ein Komplex enthaltend OCIF und einem Polysaccharid |
| JP4336467B2 (ja) * | 2001-10-15 | 2009-09-30 | 株式会社林原生物化学研究所 | 破骨細胞形成抑制因子の産生を調節し得る物質のスクリーニング方法 |
| EP1482978A1 (de) * | 2002-03-01 | 2004-12-08 | Sankyo Company, Limited | Pharmazeutische zusammensetzung enthaltend osteoklastogenesishemmungsfaktor |
| US7718776B2 (en) | 2002-04-05 | 2010-05-18 | Amgen Inc. | Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors |
| US20050014264A1 (en) * | 2002-12-11 | 2005-01-20 | University Of Massachusetts | Method of introducing siRNA into adipocytes |
| RU2323227C2 (ru) * | 2003-03-24 | 2008-04-27 | Санкио Компани Лимитед | Полимерные модификаторы и фармацевтические композиции |
| RU2359270C2 (ru) * | 2003-07-29 | 2009-06-20 | Зольвай Фармасьютиклз Гмбх | Способ анализа панкреатита и содержащих его композиций |
| US7740861B2 (en) * | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
| TWI364458B (en) * | 2004-08-27 | 2012-05-21 | Wyeth Res Ireland Ltd | Production of tnfr-lg |
| AU2005284727A1 (en) | 2004-09-17 | 2006-03-23 | University Of Massachusetts | Compositions and their uses for lysosomal enzyme deficiencies |
| ES2525096T3 (es) * | 2005-04-19 | 2014-12-17 | Kings College London | Uso de bip contra la pérdida ósea y osteoporosis |
| RU2354662C2 (ru) * | 2005-07-21 | 2009-05-10 | Андрей Георгиевич Зарайский | Способ блокирования активности activin с помощью ноггин2 |
| ATE526991T1 (de) * | 2005-10-24 | 2011-10-15 | Univ Massachusetts | Zusammensetzungen und ihre verwendungen für die gentherapeutische behandlung von knochenerkrankungen |
| ES2649983T3 (es) * | 2005-11-23 | 2018-01-16 | Acceleron Pharma, Inc. | Antagonistas de activina-ActRIIa en su uso para promover el crecimiento óseo |
| US10741034B2 (en) | 2006-05-19 | 2020-08-11 | Apdn (B.V.I.) Inc. | Security system and method of marking an inventory item and/or person in the vicinity |
| BRPI0818437B8 (pt) * | 2007-10-11 | 2021-05-25 | Daiichi Sankyo Co Ltd | anticorpo ou fragmento funcional do anticorpo, composição farmacêutica, uso de pelo menos um dos anticorpos ou fragmentos funcionais dos anticorpos, e, hibridoma |
| EP2222283A2 (de) * | 2007-10-29 | 2010-09-01 | University of Massachusetts | Zur freisetzung von nukleinsäuren (sirna) mit hefe-zellwandproteinen verkapselte mehrlagige nanopatikel |
| MX343049B (es) | 2009-04-09 | 2016-10-21 | Daiichi Sankyo Co Ltd | Anticuerpo anti-lectina similar a inmunoglobulina de union a acido sialico-15. |
| MX2013003828A (es) | 2010-10-05 | 2013-06-28 | Daiichi Sankyo Co Ltd | Anticuerpo dirigido a la proteina lectina tipo inmunoglobulina de union a acido sialico-15 relacionada con osteoclastos. |
| CN102011025A (zh) * | 2010-10-11 | 2011-04-13 | 宁波市鄞州品达电器焊料有限公司 | 一种耐超高温的无铅焊锡 |
| MX2014011828A (es) | 2012-03-30 | 2014-12-10 | Daiichi Sankyo Co Ltd | Anticuerpo anti-siglec-15 con region determinante de complementariedad modificada. |
| US9963740B2 (en) * | 2013-03-07 | 2018-05-08 | APDN (B.V.I.), Inc. | Method and device for marking articles |
| WO2015054188A1 (en) | 2013-10-07 | 2015-04-16 | Apdn (B.V.I), Inc. | Multimode image and spectral reader |
| US10745825B2 (en) | 2014-03-18 | 2020-08-18 | Apdn (B.V.I.) Inc. | Encrypted optical markers for security applications |
| CN106103121B (zh) | 2014-03-18 | 2019-12-06 | 亚普蒂恩(B.V.I.)公司 | 用于安全应用的加密光学标记物 |
| JP6339855B2 (ja) * | 2014-05-14 | 2018-06-06 | 住友ゴム工業株式会社 | エアレスタイヤ及びその製造方法 |
| CN109070130B (zh) | 2016-04-11 | 2022-03-22 | 亚普蒂恩(B V I)公司 | 用于标记纤维素产品的方法 |
| US10995371B2 (en) | 2016-10-13 | 2021-05-04 | Apdn (B.V.I.) Inc. | Composition and method of DNA marking elastomeric material |
| US10920274B2 (en) | 2017-02-21 | 2021-02-16 | Apdn (B.V.I.) Inc. | Nucleic acid coated submicron particles for authentication |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US33535A (en) * | 1861-10-22 | Improvement in machines for making bricks | ||
| US100069A (en) * | 1870-02-22 | Geokge h | ||
| US175840A (en) * | 1876-04-11 | Improvement in circular-knitting machines | ||
| US45456A (en) * | 1864-12-13 | Improved apparatus for carbureting air | ||
| US150989A (en) * | 1874-05-19 | Improvement in pin and dowel machines | ||
| US208045A (en) * | 1878-09-17 | Improvement in ether-meters for refrigerating-machines | ||
| US166097A (en) * | 1875-07-27 | Improvement in buttons for wearing apparel | ||
| US181418A (en) * | 1876-08-22 | Improvement in gas apparatus | ||
| US216297A (en) * | 1879-06-10 | Improvement in ironing-stands | ||
| US139325A (en) * | 1873-05-27 | Improvement in carriage-springs | ||
| US176647A (en) * | 1876-04-25 | Improvement in car-couplings | ||
| US127637A (en) * | 1872-06-04 | Improvement in couplings for divided axles | ||
| US100488A (en) * | 1870-03-01 | Improved tire-xjfsetting machine | ||
| US81720A (en) * | 1868-09-01 | Isaac williams | ||
| US169117A (en) * | 1875-10-26 | Improvement in revolution-indicators | ||
| US104485A (en) * | 1870-06-21 | Improvement in sleeping-cars | ||
| US86827A (en) * | 1869-02-09 | Improved rubber boot | ||
| US86826A (en) * | 1869-02-09 | Improvement in mechanical movement | ||
| US144480A (en) * | 1873-11-11 | Improvement in cutting attachments for sewing-machines | ||
| US207827A (en) * | 1878-09-10 | Improvement in siphon-condensers | ||
| US103978A (en) * | 1870-06-07 | Improvement in bee-hives | ||
| US886826A (en) * | 1907-12-14 | 1908-05-05 | Reece Button Hole Machine Co | Button-sewing machine. |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4710473A (en) | 1983-08-10 | 1987-12-01 | Amgen, Inc. | DNA plasmids |
| EP0192658A4 (de) | 1984-07-30 | 1987-07-13 | Salk Inst For Biological Studi | Retrovirale gentransfervektoren. |
| US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| JP2604135B2 (ja) | 1986-02-28 | 1997-04-30 | ライオン株式会社 | 口腔骨疾患治療剤 |
| US5266683A (en) * | 1988-04-08 | 1993-11-30 | Stryker Corporation | Osteogenic proteins |
| JPH04502854A (ja) * | 1988-10-24 | 1992-05-28 | カターソン,ブルース | 変形性関節症の初期段階の診断、モニタリングならびに治療の方法および組成物 |
| JP2877509B2 (ja) | 1989-05-19 | 1999-03-31 | アムジエン・インコーポレーテツド | メタロプロテイナーゼ阻害剤 |
| RU2018840C1 (ru) * | 1989-12-11 | 1994-08-30 | Российский научный центр "Восстановительная травматология и ортопедия" им.акад.Г.А.Илизарова | Способ моделирования стимуляции репаративного костеобразования в условиях дистракционного остеосинтеза |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| WO1992009697A1 (en) | 1990-11-30 | 1992-06-11 | Celtrix Laboratories, Inc. | USE OF A BONE MORPHOGENETIC PROTEIN IN SYNERGISTIC COMBINATION WITH TGF-β FOR BONE REPAIR |
| US5118667A (en) | 1991-05-03 | 1992-06-02 | Celtrix Pharmaceuticals, Inc. | Bone growth factors and inhibitors of bone resorption for promoting bone formation |
| CA2068389A1 (en) | 1991-05-13 | 1992-11-14 | Masahiko Sato | Method for inhibiting bone resorption |
| TW318142B (de) * | 1991-06-03 | 1997-10-21 | Mitsubishi Chemicals Co Ltd | |
| MX9204303A (es) | 1991-07-23 | 1993-11-01 | Rhone Poulenc Rorer Int | Factor regulador del crecimiento de osteoclasto. |
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| US5366859A (en) * | 1991-10-31 | 1994-11-22 | Mitsubishi Petrochemical Co., Ltd. | Radioimmunoassay method |
| US5447851B1 (en) | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
| US5427954A (en) * | 1992-04-29 | 1995-06-27 | Shriner's Hospitals For Crippled Children | Compositions and methods for detection and treatment of human osteoarthritis |
| ATE188610T1 (de) | 1992-04-30 | 2000-01-15 | Amgen Inc | Methoden zur behandlung von interleukin- 1 und - tumor - nekrose - faktor - verursachten krankheiten |
| US5585479A (en) | 1992-07-24 | 1996-12-17 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human ELAM-I RNA |
| US5578569A (en) | 1993-03-12 | 1996-11-26 | Tam; Cherk S. | Method of increasing bone growth |
| US5457035A (en) | 1993-07-23 | 1995-10-10 | Immunex Corporation | Cytokine which is a ligand for OX40 |
| ATE202571T1 (de) | 1993-09-14 | 2001-07-15 | Merck & Co Inc | Humane protein-tyrosinphosphatase decodierende cdna |
| US6268212B1 (en) | 1993-10-18 | 2001-07-31 | Amgen Inc. | Tissue specific transgene expression |
| RU2074193C1 (ru) * | 1994-06-21 | 1997-02-27 | Игорь Эдуардович Есиповский | Способ очистки альфа-фетопротеина человека |
| US6046033A (en) * | 1994-06-27 | 2000-04-04 | Snow Brand Milk Products Co., Ltd. | Basic osteoblast growth factor II (bOGF-II) |
| AU4440496A (en) | 1995-02-10 | 1996-08-22 | Smithkline Beecham Corporation | Use of src SH2 specific compounds to treat a bone resorption disease |
| US6001349A (en) | 1995-02-22 | 1999-12-14 | Therion Biologics Corporation | Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof |
| US20030166097A1 (en) | 1995-03-15 | 2003-09-04 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor |
| WO1996028546A1 (en) * | 1995-03-15 | 1996-09-19 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor |
| US7094564B1 (en) | 1995-03-15 | 2006-08-22 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor |
| US5843901A (en) | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
| AU5985996A (en) | 1995-06-07 | 1997-01-15 | Osteosa Inc. | Osteoclast growth regulatory factor |
| AU6090896A (en) | 1995-06-07 | 1997-01-15 | Osteosa Inc. | Osteoclast growth regulatory factor |
| US20030207827A1 (en) | 1995-12-22 | 2003-11-06 | William J. Boyle | Osteoprotegerin |
| US6613544B1 (en) | 1995-12-22 | 2003-09-02 | Amgen Inc. | Osteoprotegerin |
| US6369027B1 (en) | 1995-12-22 | 2002-04-09 | Amgen Inc. | Osteoprotegerin |
| JPH1057071A (ja) | 1996-08-19 | 1998-03-03 | Snow Brand Milk Prod Co Ltd | 新規dna及びそれを用いた蛋白質の製造方法 |
| US5830850A (en) * | 1996-08-28 | 1998-11-03 | Mount Sinai School Of Medicine Of The City Of New York | Methods for the treatment of bone resorption disorders, including osteoporosis |
| PT1114864E (pt) * | 1996-12-13 | 2008-10-08 | Schering Corp | Antigénios de superfície de células de mamífero, reagentes relacionados |
| WO1998028423A2 (en) | 1996-12-20 | 1998-07-02 | Board Of Regents, The University Of Texas System | Compositions and methods of use for osteoclast inhibitory factors |
| DE69740107D1 (de) | 1996-12-23 | 2011-03-10 | Immunex Corp | Rezeptor aktivator von nf-kappa b, rezeptor is mitglied der tnf rezeptor superfamilie |
| US6271349B1 (en) * | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
| ES2263204T5 (es) | 1997-04-15 | 2013-10-14 | Daiichi Sankyo Company, Limited | Nueva proteína y proceso para producir la misma |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| ES2284203T5 (es) | 1997-04-16 | 2016-03-11 | Amgen Inc. | Proteínas de unión a osteoprotegerina y sus receptores |
| US5843678A (en) | 1997-04-16 | 1998-12-01 | Amgen Inc. | Osteoprotegerin binding proteins |
| US6656508B2 (en) | 1997-04-17 | 2003-12-02 | Amgen Inc. | Sustained-release alginate gels |
| CA2288351A1 (en) | 1997-05-01 | 1998-11-05 | Amgen Inc. | Chimeric opg polypeptides |
| AU7705098A (en) | 1997-05-29 | 1998-12-30 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like protein 8 |
| JP4268684B2 (ja) | 1997-09-24 | 2009-05-27 | 第一三共株式会社 | 骨代謝異常症の診断方法 |
| US6297022B1 (en) * | 1997-10-08 | 2001-10-02 | Smithkline Beecham Corporation | Method of identifying agonists and antagonists for tumor necrosis related receptor TR1 |
| US6087555A (en) | 1997-10-15 | 2000-07-11 | Amgen Inc. | Mice lacking expression of osteoprotegerin |
| US6790823B1 (en) | 1998-04-23 | 2004-09-14 | Amgen Inc. | Compositions and methods for the prevention and treatment of cardiovascular diseases |
| AU762574B2 (en) | 1998-05-14 | 2003-06-26 | Immunex Corporation | Method of inhibiting osteoclast activity |
| HUP0104126A3 (en) | 1998-10-28 | 2004-07-28 | Sankyo Company Ltd Chuo Ku | Remedies for bone metabolic errors |
| AU6078500A (en) | 1999-07-09 | 2001-01-30 | Amgen, Inc. | Combination therapy for conditions leading to bone loss |
| IL142900A0 (en) | 1999-09-03 | 2002-04-21 | Amgen Inc | Compositions and methods for the prevention or treatment of cancer and bone loss associated with cancer |
| US20030144187A1 (en) | 1999-09-03 | 2003-07-31 | Colin R. Dunstan | Opg fusion protein compositions and methods |
| WO2001044472A1 (en) | 1999-12-16 | 2001-06-21 | Amgen, Inc. | Tnfr/opg-like molecules and uses thereof |
| US20030103978A1 (en) | 2000-02-23 | 2003-06-05 | Amgen Inc. | Selective binding agents of osteoprotegerin binding protein |
| EP2295081B1 (de) | 2001-06-26 | 2018-10-31 | Amgen Inc. | Antikörper gegen OPGL |
| EP1270015A3 (de) | 2001-06-29 | 2004-02-25 | Sankyo Company Limited | Ein Komplex enthaltend OCIF und einem Polysaccharid |
| EP1482978A1 (de) | 2002-03-01 | 2004-12-08 | Sankyo Company, Limited | Pharmazeutische zusammensetzung enthaltend osteoklastogenesishemmungsfaktor |
| EP1963515B1 (de) | 2005-12-23 | 2014-05-28 | Synthetic Genomics, Inc. | Installation von genomen oder teilweisen genomen in zellen oder zellähnlichen systemen |
-
1996
- 1996-02-19 IL IL11717596A patent/IL117175A/xx active IP Right Review Request
- 1996-02-20 RU RU97115710/04A patent/RU2194714C2/ru not_active IP Right Cessation
- 1996-02-20 DE DE69637486T patent/DE69637486D1/de not_active Expired - Lifetime
- 1996-02-20 AU AU46773/96A patent/AU702557C/en not_active Revoked
- 1996-02-20 PT PT96902484T patent/PT816380E/pt unknown
- 1996-02-20 EP EP04076464A patent/EP1528103B1/de not_active Expired - Lifetime
- 1996-02-20 DE DE69633225T patent/DE69633225T2/de not_active Expired - Lifetime
- 1996-02-20 AT AT04076464T patent/ATE391178T1/de not_active IP Right Cessation
- 1996-02-20 RU RU2002120050A patent/RU2238948C2/ru not_active IP Right Cessation
- 1996-02-20 NZ NZ301362A patent/NZ301362A/xx not_active IP Right Cessation
- 1996-02-20 JP JP52555396A patent/JP3502102B2/ja not_active Expired - Fee Related
- 1996-02-20 WO PCT/JP1996/000374 patent/WO1996026217A1/ja not_active Ceased
- 1996-02-20 CN CNB96192019XA patent/CN1218961C/zh not_active Expired - Lifetime
- 1996-02-20 KR KR1019970705767A patent/KR100381788B1/ko not_active Ceased
- 1996-02-20 AT AT96902484T patent/ATE274580T1/de not_active IP Right Cessation
- 1996-02-20 CA CA002213469A patent/CA2213469A1/en not_active Withdrawn
- 1996-02-20 HU HU9900422A patent/HU224570B1/hu not_active IP Right Cessation
- 1996-02-20 EP EP96902484A patent/EP0816380B1/de not_active Expired - Lifetime
- 1996-02-20 ES ES96902484T patent/ES2227579T3/es not_active Expired - Lifetime
- 1996-02-20 FI FI973402A patent/FI973402A7/fi unknown
- 1996-07-03 TW TW085108022A patent/TW538049B/zh active
-
1997
- 1997-08-19 NO NO19973801A patent/NO318898B1/no not_active Application Discontinuation
- 1997-08-20 US US08/915,004 patent/US7125686B1/en not_active Expired - Fee Related
- 1997-08-20 MX MX9706341A patent/MX9706341A/es not_active IP Right Cessation
-
1998
- 1998-04-17 US US09/062,113 patent/US7205397B2/en not_active Expired - Fee Related
-
2002
- 2002-09-03 US US10/232,858 patent/US6855808B2/en not_active Expired - Fee Related
-
2004
- 2004-02-25 US US10/785,114 patent/US7276344B2/en not_active Expired - Fee Related
- 2004-02-25 US US10/785,109 patent/US20040142426A1/en not_active Abandoned
- 2004-08-31 US US10/929,958 patent/US20050014229A1/en not_active Abandoned
- 2004-08-31 US US10/929,748 patent/US7468268B2/en not_active Expired - Fee Related
- 2004-11-03 US US10/979,303 patent/US20050118682A1/en not_active Abandoned
- 2004-11-03 US US10/979,654 patent/US20050124054A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL117175A (en) | Osteoclastogenesis inhibitory factor protein | |
| HUP9900920A2 (hu) | Eljárás emlőssejt-tenyészetekben termelt proteinek szializációjának szabályozására | |
| GEP20063830B (en) | Nogo Receptor-Mediated Blockade of Axonal Growth | |
| CA2066370A1 (en) | Yield when disulfide-bonded proteins are secreted | |
| ATE113982T1 (de) | Verzweigungsenzym und dessen verwendung. | |
| ATE239494T1 (de) | Heparin-binding protein zur behandlung von sepsis | |
| EP1070758A4 (de) | Neues protein und verfahren zu dessen herstellung | |
| KR960703943A (ko) | 신규단백질 및 그 제조방법 | |
| Wagner | NIF (neurite-inducing factor): a novel peptide inducing neurite formation in PC12 cells | |
| Fireman et al. | Low Molecular Weight γ-Globulins of Urine and Plasma and their Relation to 7 S γ2-Globulin | |
| JPH0725798B2 (ja) | TGF−β制御糖タンパク質 | |
| AU4315396A (en) | Monoclonal antibody | |
| KR970009339B1 (en) | Tpa from scolopendra subepinpes multilans and its purification method | |
| ATE250126T1 (de) | Methode zur herstellung rekombinanter proteine und dafür verwendete wirtszellen | |
| DE69126379D1 (de) | Verfahren zur herstellung und reinigung des carboxyterminalen fragments der dna-polymerase i von streptococcus pneumoniae | |
| FAUVEL et al. | Application of HPLC to the Separation of Glycoproteins from Endothelial Cell Culture Medium | |
| KR880701735A (ko) | 골 유도 조성물 | |
| TW363080B (en) | Process for preparing acarviosyl transferase and for using it in the conversion of acarbose homologues into acarbose, for the preparation of acarbose homologues | |
| IT1276765B1 (it) | Gene del cromosoma x umano e proteina codificata da detto gene. | |
| MX9604953A (es) | Proteina que une heparina, para el tratamiento de sepsis y procesos para su preparacion. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| ME | Application for patent revocation filed |