IL117315A - Prokinetic piperidine substituted oxadiazole derivatives their preparation and pharmaceutical compositions containing them - Google Patents

Prokinetic piperidine substituted oxadiazole derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number: IL117315A
Authority: IL; Israel
Prior art keywords: prokinetic; preparation; pharmaceutical compositions; compositions containing; oxadiazole derivatives
Prior art date: 1995-03-01

Application number

IL11731596A

Other languages

English (en)

Other versions

IL117315A0 (en

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-01

Filing date

1996-02-29

Publication date

2000-07-26

1996-02-29 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1996-06-18 Publication of IL117315A0 publication Critical patent/IL117315A0/xx

2000-07-26 Publication of IL117315A publication Critical patent/IL117315A/xx

Links

150000004866 oxadiazoles Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000003386 piperidinyl group Chemical group 0.000 title 1
NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nutrition Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IL11731596A 1995-03-01 1996-02-29 Prokinetic piperidine substituted oxadiazole derivatives their preparation and pharmaceutical compositions containing them IL117315A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP95200501		1995-03-01

Publications (2)

Publication Number	Publication Date
IL117315A0 IL117315A0 (en)	1996-06-18
IL117315A true IL117315A (en)	2000-07-26

Family

ID=8220055

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11731596A IL117315A (en)	1995-03-01	1996-02-29	Prokinetic piperidine substituted oxadiazole derivatives their preparation and pharmaceutical compositions containing them

Country Status (25)

Country	Link
US (1)	US5854261A (de)
EP (1)	EP0812321B1 (de)
JP (1)	JP3980056B2 (de)
KR (1)	KR100443554B1 (de)
CN (1)	CN1092656C (de)
AR (1)	AR003932A1 (de)
AT (1)	ATE384716T1 (de)
AU (1)	AU702932B2 (de)
BR (1)	BR9607316A (de)
CA (1)	CA2212893C (de)
CZ (1)	CZ286992B6 (de)
DE (1)	DE69637412T2 (de)
EA (1)	EA001084B1 (de)
ES (1)	ES2301166T3 (de)
FI (1)	FI973562A0 (de)
HU (1)	HUP9702395A3 (de)
IL (1)	IL117315A (de)
MY (1)	MY113584A (de)
NO (1)	NO309425B1 (de)
NZ (1)	NZ301699A (de)
PL (1)	PL183712B1 (de)
TR (1)	TR199700876T1 (de)
TW (1)	TW360653B (de)
WO (1)	WO1996026937A1 (de)
ZA (1)	ZA961652B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9603755D0 (en) *	1996-02-22	1996-04-24	Pfizer Ltd	Therapeutic agents
US6107313A (en) *	1998-10-02	2000-08-22	Combichem, Inc.	Dopamine receptor antagonists
US7332508B2 (en) *	2002-12-18	2008-02-19	Novo Nordisk A/S	Substituted homopiperidine, piperidine or pyrrolidine derivatives
GB0910667D0 (en) *	2009-06-19	2009-08-05	Glaxo Wellcome Mfg Pte Ltd	Novel compounds
PT2758394E (pt) *	2011-09-19	2015-04-22	Suven Life Sciences Ltd	Compostos heteroarilo como ligandos de recetores 5-ht4
JP2019533022A (ja) *	2016-10-24	2019-11-14	ユマニティセラピューティクス，インコーポレーテッド	化合物及びその使用
EP3566055B1 (de)	2017-01-06	2025-03-12	Janssen Pharmaceutica NV	Scd-hemmer zur behandlung von neurologischen erkrankungen
CA3083000A1 (en)	2017-10-24	2019-05-02	Yumanity Therapeutics, Inc.	Compounds and uses thereof
WO2019183587A1 (en)	2018-03-23	2019-09-26	Yumanity Therapeutics, Inc.	Compounds and uses thereof
WO2020154571A1 (en)	2019-01-24	2020-07-30	Yumanity Therapeutics, Inc.	Compounds and uses thereof
EA202192047A1 (ru)	2019-11-13	2021-12-08	Юманити Терапьютикс, Инк.	Соединения и их применение

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1183847A (en) *	1981-10-01	1985-03-12	Georges Van Daele	N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5374637A (en) *	1989-03-22	1994-12-20	Janssen Pharmaceutica N.V.	N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
GB9005014D0 (en) *	1990-03-06	1990-05-02	Janssen Pharmaceutica Nv	N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
EP0596933A1 (de) *	1991-08-03	1994-05-18	Smithkline Beecham Plc	5-HT4 Rezeptor - Antigonisten
GB9202797D0 (en)	1992-02-11	1992-03-25	Milsom Jonathan	Glazed units
EP0664805A1 (de) *	1992-10-13	1995-08-02	Smithkline Beecham Plc	Heterozyklische karbonsäure-estern oder amide verwendbar als 5-ht4 rezeptor antagonisten
MX9306311A (es) *	1992-10-13	1994-04-29	Smithkline Beecham Plc	Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
EP0667867A1 (de) *	1992-11-05	1995-08-23	Smithkline Beecham Plc	Piperidinderivate als 5-ht4 rezeptor antagonisten
JPH06157518A (ja) *	1992-11-27	1994-06-03	Yamanouchi Pharmaceut Co Ltd	新規なオキサジアゾール誘導体又はその塩
AU6856094A (en) *	1994-06-01	1995-12-21	Yamanouchi Pharmaceutical Co., Ltd.	Oxadiazole derivative and medicinal composition thereof

1996
- 1996-02-15 TW TW085101860A patent/TW360653B/zh not_active IP Right Cessation
- 1996-02-21 ES ES96903000T patent/ES2301166T3/es not_active Expired - Lifetime
- 1996-02-21 CZ CZ19972723A patent/CZ286992B6/cs not_active IP Right Cessation
- 1996-02-21 BR BR9607316A patent/BR9607316A/pt not_active Application Discontinuation
- 1996-02-21 JP JP52601096A patent/JP3980056B2/ja not_active Expired - Lifetime
- 1996-02-21 AT AT96903000T patent/ATE384716T1/de not_active IP Right Cessation
- 1996-02-21 KR KR1019970705701A patent/KR100443554B1/ko not_active Expired - Fee Related
- 1996-02-21 US US08/894,340 patent/US5854261A/en not_active Expired - Lifetime
- 1996-02-21 WO PCT/EP1996/000784 patent/WO1996026937A1/en not_active Ceased
- 1996-02-21 HU HU9702395A patent/HUP9702395A3/hu unknown
- 1996-02-21 CN CN96192300A patent/CN1092656C/zh not_active Expired - Fee Related
- 1996-02-21 TR TR97/00876T patent/TR199700876T1/xx unknown
- 1996-02-21 CA CA002212893A patent/CA2212893C/en not_active Expired - Lifetime
- 1996-02-21 AU AU47188/96A patent/AU702932B2/en not_active Ceased
- 1996-02-21 EA EA199700205A patent/EA001084B1/ru not_active IP Right Cessation
- 1996-02-21 DE DE69637412T patent/DE69637412T2/de not_active Expired - Lifetime
- 1996-02-21 EP EP96903000A patent/EP0812321B1/de not_active Expired - Lifetime
- 1996-02-21 PL PL96322019A patent/PL183712B1/pl not_active IP Right Cessation
- 1996-02-21 NZ NZ301699A patent/NZ301699A/en not_active IP Right Cessation
- 1996-02-29 ZA ZA9601652A patent/ZA961652B/xx unknown
- 1996-02-29 MY MYPI96000748A patent/MY113584A/en unknown
- 1996-02-29 AR ARP960101592A patent/AR003932A1/es unknown
- 1996-02-29 IL IL11731596A patent/IL117315A/xx not_active IP Right Cessation
1997
- 1997-08-19 NO NO973808A patent/NO309425B1/no not_active IP Right Cessation
- 1997-08-29 FI FI973562A patent/FI973562A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
BR9607316A (pt)	1997-12-30
ATE384716T1 (de)	2008-02-15
EP0812321B1 (de)	2008-01-23
DE69637412T2 (de)	2009-01-22
CA2212893A1 (en)	1996-09-06
HUP9702395A3 (en)	1999-10-28
NO973808L (no)	1997-08-19
PL183712B1 (pl)	2002-07-31
CA2212893C (en)	2007-01-16
FI973562A7 (fi)	1997-08-29
PL322019A1 (en)	1998-01-05
NO309425B1 (no)	2001-01-29
EP0812321A1 (de)	1997-12-17
TR199700876T1 (xx)	1998-02-21
CN1092656C (zh)	2002-10-16
AR003932A1 (es)	1998-09-30
CN1177352A (zh)	1998-03-25
FI973562A0 (fi)	1997-08-29
MY113584A (en)	2002-04-30
AU702932B2 (en)	1999-03-11
CZ272397A3 (cs)	1998-02-18
US5854261A (en)	1998-12-29
EA001084B1 (ru)	2000-10-30
MX9706622A (es)	1997-11-29
WO1996026937A1 (en)	1996-09-06
IL117315A0 (en)	1996-06-18
NO973808D0 (no)	1997-08-19
NZ301699A (en)	1998-02-26
JP3980056B2 (ja)	2007-09-19
AU4718896A (en)	1996-09-18
JPH11501021A (ja)	1999-01-26
CZ286992B6 (en)	2000-08-16
DE69637412D1 (de)	2008-03-13
ES2301166T3 (es)	2008-06-16
TW360653B (en)	1999-06-11
KR19980702304A (ko)	1998-07-15
EA199700205A1 (ru)	1998-02-26
HUP9702395A2 (hu)	1999-09-28
KR100443554B1 (ko)	2004-10-06
ZA961652B (en)	1997-09-11

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Legal Events

Date	Code	Title
2000-12-06	FF	Patent granted
2006-04-10	KB	Patent renewed
2010-12-30	MM9K	Patent not in force due to non-payment of renewal fees