IL117613A - Lower alcohol solvates of olanzapine and the preparation therefrom of technical grade olanzapine - Google Patents

Lower alcohol solvates of olanzapine and the preparation therefrom of technical grade olanzapine

Info

Publication number: IL117613A
Authority: IL; Israel
Prior art keywords: olanzapine; lower alcohol; technical grade; alcohol solvates; preparation therefrom
Prior art date: 1995-03-24

Application number

IL11761396A

Other languages

English (en)

Other versions

IL117613A0 (en

Original Assignee

Lilly Co Eli

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-24

Filing date

1996-03-22

Publication date

2000-07-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27020696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL117613(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-03-24 Priority claimed from US08/410,474 external-priority patent/US5631250A/en

1996-03-22 Application filed by Lilly Co Eli, Lilly Industries Ltd filed Critical Lilly Co Eli

1996-07-23 Publication of IL117613A0 publication Critical patent/IL117613A0/xx

2000-07-16 Publication of IL117613A publication Critical patent/IL117613A/xx

Links

KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title 2
229960005017 olanzapine Drugs 0.000 title 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
239000012453 solvate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL11761396A 1995-03-24 1996-03-22 Lower alcohol solvates of olanzapine and the preparation therefrom of technical grade olanzapine IL117613A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US40956695A	1995-03-24	1995-03-24
US08/410,474 US5631250A (en)	1995-03-24	1995-03-24	Process and solvate of 2-methyl-thieno-benzodiazepine

Publications (2)

Publication Number	Publication Date
IL117613A0 IL117613A0 (en)	1996-07-23
IL117613A true IL117613A (en)	2000-07-16

Family

ID=27020696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11761396A IL117613A (en)	1995-03-24	1996-03-22	Lower alcohol solvates of olanzapine and the preparation therefrom of technical grade olanzapine

Country Status (17)

Country	Link
EP (1)	EP0733634B1 (de)
AR (2)	AR002721A1 (de)
AT (1)	ATE197711T1 (de)
AU (1)	AU5257896A (de)
CO (1)	CO4700300A1 (de)
DE (1)	DE69611003T2 (de)
DK (1)	DK0733634T3 (de)
EG (1)	EG24221A (de)
ES (1)	ES2151991T3 (de)
GR (1)	GR3035355T3 (de)
IL (1)	IL117613A (de)
MY (1)	MY116503A (de)
PE (1)	PE38197A1 (de)
PT (1)	PT733634E (de)
SI (1)	SI0733634T1 (de)
WO (1)	WO1996030374A1 (de)
YU (1)	YU49276B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ299247B6 (cs) *	1996-09-23	2008-05-28	Eli Lilly And Company	Olanzapin dihydrát D
ZA978515B (en) *	1996-09-23	1999-03-23	Lilly Co Eli	Intermediates and process for preparing olanzapine
FR2802101B1 (fr)	1999-12-10	2003-02-28	Aventis Pharma Sa	Association de cymemazine et d'un neuroleptique atypique
US7297789B2 (en)	2002-05-31	2007-11-20	Sandoz, Inc.	Process of preparation of olanzapine form I
SI21270A (sl) *	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en)	2002-12-24	2008-01-29	Teva Pharmaceutical Industries Ltd.	Crystal forms, methods for their preparation and method for preparation of olanzapine
DE602004014264D1 (de)	2003-12-22	2008-07-17	Teva Pharma	Verfahren zur herstellung von olanzapin
EP1716154A1 (de) *	2004-02-19	2006-11-02	Neuland Laboratories Ltd	Verfahren zur herstellung der form 1 von olanzapin, die sich als antipsychotisches arzneimittel eignet
ES2253091B1 (es) *	2004-07-27	2007-02-01	Inke, S.A.	Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
PL1838716T3 (pl)	2005-01-05	2011-09-30	Lilly Co Eli	Dihydrat embonianu olanzapiny
CA2593407A1 (en) *	2007-06-22	2008-12-22	Apotex Pharmachem Inc.	Improved processes for the synthesis of olanzapine
CU20090172A6 (es)	2009-10-09	2011-10-05	Facultad De Quimica Universidad De La Habana	Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular
EP2486913A1 (de)	2011-02-14	2012-08-15	Labtec GmbH	Orale Filmformulierungen für Olanzapin mit schneller Zersetzung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4237279A (en) *	1979-07-27	1980-12-02	Eli Lilly And Company	Crystalline 3-hydroxycephalosporin solvates
US5229382A (en) *	1990-04-25	1993-07-20	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
GB9009229D0 (en) *	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
DK0582368T3 (da) *	1992-05-29	2001-02-05	Lilly Co Eli	Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet
US5439888A (en) *	1994-03-04	1995-08-08	Eli Lilly And Company	Antithrombotic agents
US5457101A (en) *	1994-06-03	1995-10-10	Eli Lilly And Company	Thieno[1,5]benzoidiazepine use

1996
- 1996-03-12 EG EG25396A patent/EG24221A/xx active
- 1996-03-22 AR ARP960101881A patent/AR002721A1/es not_active Application Discontinuation
- 1996-03-22 AT AT96301999T patent/ATE197711T1/de active
- 1996-03-22 SI SI9630280T patent/SI0733634T1/xx unknown
- 1996-03-22 IL IL11761396A patent/IL117613A/xx not_active IP Right Cessation
- 1996-03-22 ES ES96301999T patent/ES2151991T3/es not_active Expired - Lifetime
- 1996-03-22 AU AU52578/96A patent/AU5257896A/en not_active Abandoned
- 1996-03-22 CO CO96014565A patent/CO4700300A1/es unknown
- 1996-03-22 EP EP96301999A patent/EP0733634B1/de not_active Expired - Lifetime
- 1996-03-22 YU YU17696A patent/YU49276B/sh unknown
- 1996-03-22 DK DK96301999T patent/DK0733634T3/da active
- 1996-03-22 AR ARP960101882A patent/AR004169A1/es active IP Right Grant
- 1996-03-22 WO PCT/US1996/003854 patent/WO1996030374A1/en not_active Ceased
- 1996-03-22 MY MYPI96001068A patent/MY116503A/en unknown
- 1996-03-22 PT PT96301999T patent/PT733634E/pt unknown
- 1996-03-22 PE PE1996000202A patent/PE38197A1/es not_active IP Right Cessation
- 1996-03-22 DE DE69611003T patent/DE69611003T2/de not_active Expired - Lifetime
2001
- 2001-02-02 GR GR20010400180T patent/GR3035355T3/el unknown

Also Published As

Publication number	Publication date
EP0733634B1 (de)	2000-11-22
PE38197A1 (es)	1997-10-16
DE69611003D1 (de)	2000-12-28
DE69611003T2 (de)	2001-05-10
PT733634E (pt)	2001-04-30
EG24221A (en)	2008-11-10
AU5257896A (en)	1996-10-16
SI0733634T1 (en)	2001-06-30
AR004169A1 (es)	1998-11-04
ATE197711T1 (de)	2000-12-15
AR002721A1 (es)	1998-04-29
YU17696A (sh)	1998-07-10
DK0733634T3 (da)	2000-12-11
ES2151991T3 (es)	2001-01-16
YU49276B (sh)	2005-03-15
MY116503A (en)	2004-02-28
GR3035355T3 (en)	2001-05-31
CO4700300A1 (es)	1998-12-29
EP0733634A1 (de)	1996-09-25
IL117613A0 (en)	1996-07-23
WO1996030374A1 (en)	1996-10-03

Legal Events

Date	Code	Title
2000-11-21	FF	Patent granted
2006-06-18	KB	Patent renewed
2010-10-31	KB	Patent renewed
2014-11-30	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
EG20992A (en)	2000-08-30	Container and method of making the same
GB2347867B (en)	2002-08-21	Flushable release liners and methods of making the same
HUP9802824A3 (en)	2000-01-28	Novel crystal form of the 2-methyl-4-(4-methyl-1-piprezinyl)-10h-thieno[2,3-b][1,5]benzodiazepine and process for its preparation
GB9526560D0 (en)	1996-02-28	Use of 2-Amino-Heterocycles
EP0940138A4 (de)	2001-03-21	Gleitmittel und verfahren zur herstellung des darin verwendeten stearinsäureethylesters
EP0741159A3 (de)	1997-10-01	Verfahren zur Herstellung von Polysiloxanen
IL117613A (en)	2000-07-16	Lower alcohol solvates of olanzapine and the preparation therefrom of technical grade olanzapine
IL122844A0 (en)	1998-08-16	Macrolides their preparation and use
NZ300198A (en)	1999-02-25	Preparation of n-arylhydroxylamines and n-hetarylhydroxylamines
IL111186A0 (en)	1994-12-29	Process for the preparation of microspheres and microspheres made thereby
HU9603447D0 (en)	1997-02-28	Liquid absorbent article and method for making thereof
GB9011841D0 (en)	1990-07-18	Tissue dispenser and method of making the same
ZA96725B (en)	1996-08-20	Use of phenyclyclohexylcarboxamides
ZA964981B (en)	1997-01-24	Isolation of naturally occurring isoflavonone and some clinical uses thereof
EP0934488A4 (de)	1999-12-08	Integrierter strahlformer und entsprechendes herstellungsverfahren
GB9611420D0 (en)	1996-08-07	Use of salicyclic acid-glucosyl transferase
NZ307236A (en)	1998-12-23	Preparation of streptogramins
EP0830336A4 (de)	2000-04-05	Verfahren zur herstellung von tertiären aminocarbonaten und aminoethern
HUP9801983A3 (en)	1999-08-30	Preparation of cis-4-o-protected-2-cyclopentenol and cyclopentanol derivatives
SG48489A1 (en)	1998-04-17	Fluid containers and methods of manufacture thereof
IL117844A0 (en)	1996-08-04	Use of (s)-adenosyl-l-methionine
GB9104489D0 (en)	1991-04-17	Tissue dispenser and method of making the same
AU126744S (en)	1996-05-22	Set of containers
ZA962440B (en)	1996-10-01	Destressing of railtracks
GB9519169D0 (en)	1995-11-22	Packaging and methods of manufacture