IL120637A - Retinoids their preparation and pharmaceutical compositions containing them - Google Patents

Retinoids their preparation and pharmaceutical compositions containing them

Info

Publication number: IL120637A
Authority: IL; Israel
Prior art keywords: retinoids; preparation; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1996-04-15

Application number

IL12063797A

Other languages

English (en)

Other versions

IL120637A0 (en

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-15

Filing date

1997-04-10

Publication date

2000-11-21

1997-04-10 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-08-14 Publication of IL120637A0 publication Critical patent/IL120637A0/xx

2000-11-21 Publication of IL120637A publication Critical patent/IL120637A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/62—Unsaturated compounds containing ether groups, groups, groups, or groups containing rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL12063797A 1996-04-15 1997-04-10 Retinoids their preparation and pharmaceutical compositions containing them IL120637A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP96105849		1996-04-15

Publications (2)

Publication Number	Publication Date
IL120637A0 IL120637A0 (en)	1997-08-14
IL120637A true IL120637A (en)	2000-11-21

Family

ID=8222666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12063797A IL120637A (en)	1996-04-15	1997-04-10	Retinoids their preparation and pharmaceutical compositions containing them

Country Status (28)

Country	Link
US (1)	US5990329A (da)
JP (1)	JP2801589B2 (da)
KR (1)	KR100240542B1 (da)
CN (1)	CN1116270C (da)
AR (1)	AR006632A1 (da)
AT (1)	ATE187962T1 (da)
AU (1)	AU715816B2 (da)
BR (1)	BR9701790A (da)
CA (1)	CA2202228C (da)
CO (1)	CO4890844A1 (da)
CZ (1)	CZ113397A3 (da)
DE (1)	DE59700872D1 (da)
DK (1)	DK0802181T3 (da)
ES (1)	ES2141556T3 (da)
HR (1)	HRP970204B1 (da)
HU (1)	HU220112B (da)
IL (1)	IL120637A (da)
MA (1)	MA24142A1 (da)
NO (1)	NO308842B1 (da)
NZ (1)	NZ314525A (da)
PE (1)	PE42498A1 (da)
PL (1)	PL319477A1 (da)
PT (1)	PT802181E (da)
SG (1)	SG52949A1 (da)
TR (1)	TR199700297A2 (da)
TW (1)	TW442459B (da)
YU (1)	YU14997A (da)
ZA (1)	ZA972944B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL142094A0 (en)	1998-09-29	2002-03-10	Gamida Cell Ltd	Methods of controlling proliferation and differentiation of stem and progenitor cells
IL152904A0 (en)	2002-01-24	2003-06-24	Gamida Cell Ltd	Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
EP1465982A4 (en)	2002-01-25	2006-06-07	Gamida Cell Ltd	PROCESS FOR EXPANSION OF STEM AND PRESERVATIVE CELLS AND EXPANDED CELL POPULATIONS THEREWITH OBTAINED
WO2006030442A2 (en)	2004-09-16	2006-03-23	Gamida-Cell Ltd.	Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
US8846393B2 (en)	2005-11-29	2014-09-30	Gamida-Cell Ltd.	Methods of improving stem cell homing and engraftment
WO2013121426A1 (en)	2012-02-13	2013-08-22	Gamida-Cell Ltd.	Culturing of mesenchymal stem cells
US9567569B2 (en)	2012-07-23	2017-02-14	Gamida Cell Ltd.	Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en)	2012-07-23	2015-11-03	Gamida Cell Ltd.	Enhancement of natural killer (NK) cell proliferation and activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4169103A (en) *	1978-04-12	1979-09-25	Hoffmann-La Roche Inc.	Nonatetraenoic acid derivatives
DE2843901A1 (de) *	1978-10-07	1980-04-24	Basf Ag	Mittel, enthaltend all-e- oder 13-z-7, 8-dehydro-retinsaeure
CH658387A5 (de) *	1984-04-02	1986-11-14	Hoffmann La Roche	Pharmazeutische praeparate.
CZ282548B6 (cs) *	1992-01-22	1997-08-13	F. Hoffmann-La Roche Ag	Farmaceutický přípravek

1997
- 1997-04-01 TW TW086104127A patent/TW442459B/zh not_active IP Right Cessation
- 1997-04-03 US US08/832,493 patent/US5990329A/en not_active Expired - Fee Related
- 1997-04-04 NZ NZ314525A patent/NZ314525A/en unknown
- 1997-04-04 AU AU17726/97A patent/AU715816B2/en not_active Ceased
- 1997-04-07 PT PT97105715T patent/PT802181E/pt unknown
- 1997-04-07 DK DK97105715T patent/DK0802181T3/da active
- 1997-04-07 ZA ZA9702944A patent/ZA972944B/xx unknown
- 1997-04-07 AT AT97105715T patent/ATE187962T1/de not_active IP Right Cessation
- 1997-04-07 ES ES97105715T patent/ES2141556T3/es not_active Expired - Lifetime
- 1997-04-07 DE DE59700872T patent/DE59700872D1/de not_active Expired - Fee Related
- 1997-04-08 JP JP9088976A patent/JP2801589B2/ja not_active Expired - Fee Related
- 1997-04-08 SG SG1997001077A patent/SG52949A1/en unknown
- 1997-04-09 CA CA002202228A patent/CA2202228C/en not_active Expired - Fee Related
- 1997-04-10 IL IL12063797A patent/IL120637A/xx not_active IP Right Cessation
- 1997-04-11 PE PE1997000288A patent/PE42498A1/es not_active Application Discontinuation
- 1997-04-11 HU HU9700747A patent/HU220112B/hu not_active IP Right Cessation
- 1997-04-14 BR BR9701790A patent/BR9701790A/pt not_active Application Discontinuation
- 1997-04-14 AR ARP970101478A patent/AR006632A1/es active IP Right Grant
- 1997-04-14 TR TR97/00297A patent/TR199700297A2/xx unknown
- 1997-04-14 YU YU14997A patent/YU14997A/sh unknown
- 1997-04-14 NO NO971711A patent/NO308842B1/no not_active IP Right Cessation
- 1997-04-14 CZ CZ971133A patent/CZ113397A3/cs unknown
- 1997-04-14 HR HR970204A patent/HRP970204B1/xx not_active IP Right Cessation
- 1997-04-14 PL PL97319477A patent/PL319477A1/xx unknown
- 1997-04-14 KR KR1019970013571A patent/KR100240542B1/ko not_active Expired - Fee Related
- 1997-04-14 CO CO97019156A patent/CO4890844A1/es unknown
- 1997-04-15 CN CN97110367A patent/CN1116270C/zh not_active Expired - Fee Related
- 1997-04-15 MA MA24555A patent/MA24142A1/fr unknown

Also Published As

Publication number	Publication date
NO971711D0 (no)	1997-04-14
JPH1036343A (ja)	1998-02-10
AU715816B2 (en)	2000-02-10
ATE187962T1 (de)	2000-01-15
MA24142A1 (fr)	1997-12-31
JP2801589B2 (ja)	1998-09-21
CN1116270C (zh)	2003-07-30
AU1772697A (en)	1997-10-23
HK1003054A1 (en)	1998-10-09
NO308842B1 (no)	2000-11-06
CA2202228A1 (en)	1997-10-15
HU9700747D0 (en)	1997-05-28
AR006632A1 (es)	1999-09-08
NZ314525A (en)	1998-02-26
TR199700297A2 (xx)	1997-11-21
US5990329A (en)	1999-11-23
ZA972944B (en)	1997-10-15
HUP9700747A3 (en)	1998-04-28
CN1167752A (zh)	1997-12-17
SG52949A1 (en)	1998-09-28
YU14997A (sh)	1999-09-27
TW442459B (en)	2001-06-23
HU220112B (hu)	2001-11-28
IL120637A0 (en)	1997-08-14
NO971711L (no)	1997-10-16
CO4890844A1 (es)	2000-02-28
CZ113397A3 (cs)	1998-02-18
DE59700872D1 (de)	2000-01-27
HUP9700747A1 (en)	1997-12-29
CA2202228C (en)	2007-03-06
PL319477A1 (en)	1997-10-27
HRP970204A2 (en)	1998-04-30
HRP970204B1 (en)	2000-10-31
MX9702697A (es)	1997-10-31
BR9701790A (pt)	1998-11-10
DK0802181T3 (da)	2000-04-17
KR970069969A (ko)	1997-11-07
PE42498A1 (es)	1998-08-18
KR100240542B1 (ko)	2000-01-15
PT802181E (pt)	2000-05-31
ES2141556T3 (es)	2000-03-16

Legal Events

Date	Code	Title
2001-04-30	FF	Patent granted
2001-07-24	KB	Patent renewed
2004-01-04	RH1	Patent not in force

Publication	Publication Date	Title
IL121236A0 (en)	1998-01-04	Cycloalkano-pyridines their preparation and pharmaceutical compositions containing them
IL117860A0 (en)	1996-08-04	Substituted 1-phenyl-3-pyrazolecarboxamides their preparation and pharmaceutical compositions containing them
IL114622A0 (en)	1995-11-27	Heteroaryl-oxazolidinones and pharmaceutical compositions containing them
IL119078A (en)	2003-11-23	Substituted benzylaminopiperidine compounds and pharmaceutical compositions comprising them
IL122293A0 (en)	1998-04-05	Substituted 4-phenylaminothiazoles their preparation and pharmaceutical compositions containing them
IL116851A (en)	2000-06-01	3-arylidene-2-oxindole derivatives and pharmaceutical compositions containing them
HUP0003761A3 (en)	2001-04-28	Substituted alkanohydroxamic acids and pharmaceutical compositions containing them
HUP9900424A2 (hu)	1999-05-28	Tiazolil-benzfurán-származékok és a vegyületeket tartalmazó gyógyászati készítmények
HUP0001309A3 (en)	2000-12-28	1-phenyl-4-benzylpiperazines and pharmaceutical compositions containing them
IL122618A0 (en)	1998-08-16	Substituted imidazolylacetonitrile compounds their preparation and pharmaceutical compositions containing them
IL114925A0 (en)	1995-12-08	Glycinamide derivatives their preparation and pharmaceutical compositions containing them
IL125710A0 (en)	1999-04-11	Arylglycinamide derivatives their preparation and pharmaceutical compositions containing them
IL115905A0 (en)	1996-01-31	Sordarin derivatives their preparation and pharmaceutical compositions containing them
IL119559A0 (en)	1997-02-18	Purin -6- one derivatives their preparation and pharmaceutical compositions containing them
IL117554A0 (en)	1996-07-23	Imidazoquinazolines their preparation and pharmaceutical compositions containing them
HUP9901452A3 (en)	2001-02-28	Bicyclic-aromatic compounds and pharmaceutical compositions containing them
IL112889A (en)	1999-06-20	Beta-lactams their preparation and pharmaceutical compositions containing them
IL123322A0 (en)	1998-09-24	Tetrahydroquinolines their preparation and pharmaceutical compositions containing them
IL125998A0 (en)	1999-04-11	Taxoids preparation thereof and pharmaceutical compositions containing them
HUP0000460A3 (en)	2001-04-28	Imidazopyridazines and pharmaceutical compositions thereof
IL114623A0 (en)	1995-11-27	Substituted triazolylmethylphenylnaph-thyridones their preparation and pharmaceutical compositions containing them
IL118672A0 (en)	1996-10-16	Benzisothiazolyl-substituted aminomethylchromans their preparation and pharmaceutical compositions containing them
IL119371A0 (en)	1997-01-10	Sulfonylaminopyrimidines their preparation and pharmaceutical compositions containing them
IL120637A0 (en)	1997-08-14	Retinoids their preparation and pharmaceutical compositions containing them
IL118141A0 (en)	1996-09-12	Tetralines their preparation and pharmaceutical compositions containing them