IL122011A - Human beta 2 integrin alpha subunit - Google Patents

Human beta 2 integrin alpha subunit

Info

Publication number
IL122011A
IL122011A IL12201197A IL12201197A IL122011A IL 122011 A IL122011 A IL 122011A IL 12201197 A IL12201197 A IL 12201197A IL 12201197 A IL12201197 A IL 12201197A IL 122011 A IL122011 A IL 122011A
Authority
IL
Israel
Prior art keywords
leu
ser
val
gly
ala
Prior art date
Application number
IL12201197A
Other languages
English (en)
Other versions
IL122011A0 (en
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Publication of IL122011A0 publication Critical patent/IL122011A0/xx
Publication of IL122011A publication Critical patent/IL122011A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL12201197A 1996-02-22 1997-02-24 Human beta 2 integrin alpha subunit IL122011A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/605,672 US5817515A (en) 1993-12-23 1996-02-22 Human B2 integrin alpha subunit antibodies
PCT/US1997/002713 WO1997031099A1 (en) 1996-02-22 1997-02-24 Human beta 2 integrin alpha subunit

Publications (2)

Publication Number Publication Date
IL122011A0 IL122011A0 (en) 1998-03-10
IL122011A true IL122011A (en) 2001-05-20

Family

ID=24424704

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12201197A IL122011A (en) 1996-02-22 1997-02-24 Human beta 2 integrin alpha subunit

Country Status (18)

Country Link
US (1) US5817515A (de)
EP (1) EP0835301B1 (de)
JP (1) JP2001526524A (de)
CN (1) CN1103812C (de)
AT (1) ATE293685T1 (de)
AU (1) AU723110B2 (de)
BR (1) BR9702101A (de)
CA (1) CA2218755C (de)
CZ (1) CZ287921B6 (de)
DE (1) DE69733051D1 (de)
FI (1) FI974018A7 (de)
HU (1) HU223977B1 (de)
IL (1) IL122011A (de)
NO (1) NO318764B1 (de)
PL (1) PL187013B1 (de)
RU (1) RU2183671C2 (de)
SK (1) SK283135B6 (de)
WO (1) WO1997031099A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6620915B2 (en) * 1993-12-23 2003-09-16 Icos Corporation Monoclonal antibodies specific for integrin α-d subunit
US5837478A (en) * 1993-12-23 1998-11-17 Icos Corporation Method of identifying modulators of binding between and VCAM-1
US20030055231A1 (en) * 1998-10-28 2003-03-20 Jian Ni 12 human secreted proteins
AU4574501A (en) 2000-03-17 2001-10-03 Millennium Pharm Inc Method of inhibiting stenosis and restenosis
WO2023235971A1 (en) * 2022-06-08 2023-12-14 The Regents Of The University Of California Antibodies and immunotherapies that target the active conformation of integrin beta 2

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271139A (en) * 1978-03-27 1981-06-02 Hiram Hart Scintillation proximity assay
US4568649A (en) * 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
WO1992006697A1 (en) * 1990-10-23 1992-04-30 Repligen Corporation Anti-inflammatory composition
JPH07502727A (ja) * 1991-10-01 1995-03-23 ザ・ジエネラル・ホスピタル・コーポレーシヨン 接着分子に対する抗体を用いた同種移植片拒絶の防止
AU2777092A (en) * 1991-10-04 1993-05-03 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Treatment of ocular inflammation by blockage of cell adhesion molecules
US5470953A (en) * 1993-12-23 1995-11-28 Icos Corporation Human β2 integrin α subunit
EP0757697A4 (de) * 1994-04-12 2000-05-17 Boehringer Ingelheim Pharma Verwendung von agentien, die die interzellülare wechselwirkung inhibieren, in der behandlung von viralen infektionen des atemweges

Also Published As

Publication number Publication date
HUP9901579A3 (en) 2001-10-29
HU223977B1 (hu) 2005-03-29
SK283135B6 (sk) 2003-03-04
HUP9901579A2 (hu) 1999-08-30
EP0835301A1 (de) 1998-04-15
FI974018L (fi) 1997-12-03
EP0835301B1 (de) 2005-04-20
FI974018A0 (fi) 1997-10-21
JP2001526524A (ja) 2001-12-18
AU723110B2 (en) 2000-08-17
WO1997031099A1 (en) 1997-08-28
NO974852L (no) 1997-12-19
CN1103812C (zh) 2003-03-26
RU2183671C2 (ru) 2002-06-20
US5817515A (en) 1998-10-06
ATE293685T1 (de) 2005-05-15
CZ287921B6 (cs) 2001-03-14
NO974852D0 (no) 1997-10-21
SK140997A3 (en) 1998-09-09
CA2218755C (en) 1999-08-31
DE69733051D1 (de) 2005-05-25
FI974018A7 (fi) 1997-12-03
PL323195A1 (en) 1998-03-16
CA2218755A1 (en) 1997-08-28
AU2133397A (en) 1997-09-10
IL122011A0 (en) 1998-03-10
BR9702101A (pt) 1999-07-20
CN1189851A (zh) 1998-08-05
CZ328697A3 (cs) 1998-07-15
PL187013B1 (pl) 2004-04-30
NO318764B1 (no) 2005-05-02

Similar Documents

Publication Publication Date Title
EP0686161B1 (de) Alpha untereinheit des humanen beta-2 integrins
US6432404B1 (en) Methods of inhibiting locomotor damage following spinal cord injury with α D-specific antibodies
AU740106B2 (en) Novel human beta2 integrin alpha subunit
AU2001296839A1 (en) Use of anti-human integrin alpha D antibodies to treat spinal cord injury
US6251395B1 (en) Methods of inhibiting inflammation at the site of a central nervous system injury with alphaD-specific antibodies
AU775300B2 (en) Method for inhibiting macrophage infiltration using monoclonal anti-alpha-d-antibodies
US5728533A (en) Human β2 integrin αsubunit
EP0835301B1 (de) Monoklonaler antikörper gegen ratte beta-2-integrin alpha d untereinheit und entsprechendes hybridoma
US5831029A (en) Human β2 integrin α subunit
EP2182008A2 (de) Monoklonaler anti alpha-D (ITGAD) Antikörper zur Behandlung von Inflammation
HK1011999B (en) Novel human beta2 integrin alpha subunit

Legal Events

Date Code Title Description
FF Patent granted
NE Application for restoration - patent lapsed through non-payment of renewal fees (section 60, patents law, 5727-1967)
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
ERR Corrigendum

Free format text: ADD SECOND APPLICANT DAIICHI SANKYO COMPANY, LIMITED